Role Description This person will: - Lead discovery pharmacology strategy and execution from target concept through candidate nomination and IND-enabling entry, with modality-informed approaches for small molecules, peptides, small biologics, and antisense oligonucleotides. - Design, execute, troubleshoot, and interpret biochemical, biophysical, cell-based, functional, and mechanism-of-action assays that establish potency, efficacy, selectivity, target engagement, drug-like properties, and biological relevance using a 100% external model with CROs and academic collaborators. - Own the pharmacology work needed to link exposure, target engagement, pharmacodynamic response, tolerability, early look at translational biomarkers, and early regulatory expectations into a clear rationale for advancing discovery programs. - Mentor and develop scientific talent while fostering a culture of rigorous experimental design, cross-functional collaboration, accountability, and continuous learning. Responsibilities - Generate, analyze, and synthesize pharmacology datasets to characterize drug-like properties, establish proof of concept, define liabilities and/or optimization opportunities, and recommend next experiments, using a 100% externalized model. - Support or lead early in vivo or ex vivo proof-of-concept studies when needed, ensuring that study design is tied to the pharmacology hypothesis and stage-appropriate decision criteria. - Apply experience across therapeutic modalities, including small molecules, peptides, small biologics, and antisense oligonucleotides, to select appropriate assay formats and interpretation frameworks. - Conduct deep scientific diligence on new targets to develop target rationale and experimental paradigm. - Partner closely with toxicology, bioanalytical, translational biology, and clinical pharmacology colleagues to connect pharmacology readouts with exposure, target engagement, and early developability considerations. - Manage and direct CROs, academic collaborators, and external partners. - Prepare concise scientific updates, program/project/study summaries, decision memos, and recommendations for project teams and leadership, with emphasis on data-driven early discovery choices. - Mentor junior scientists and research associates while remaining directly engaged in experimental strategy, data review, and problem solving. Qualifications - PhD in Toxicology, Pharmacology, Molecular or Cell Biology, or a related science with 4 years industry experience; or Masters with 6 years industry experience; or BSci with 10 years industry experience. - Must have at least 2 years working in small biotech to be considered, previous remote work is highly desirable. - Demonstrated experience developing and executing pharmacology and early proof of concept studies to support drug discovery, candidate selection, IND-enabling studies, regulatory submissions, and clinical development. - Experience authoring, reviewing, and contributing to scientific publications and scientific experimental summary documents. - Demonstrated ability to interpret complex biology, physiology, and biochemical data into a drug-product specific mechanism of action. - Experienced leading external CROs, consultants, and sponsored research agreements to successfully deliver nonclinical development objectives in tight timelines. - Demonstrated success working in cross-functional teams. - Strong and independent organizational skills, with excellent written, verbal, and presentation abilities to effectively communicate scientific concepts to diverse audiences including executive leadership. - Can travel domestically/internationally up to 20-25%. Work Location and Conditions - At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan, and Tennessee. - You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested. - You must have access to work in a setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location. Compensation The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity. Estimated Pay Range: $186,000 — $209,000 USD Equal Opportunity Employer Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

LIHTC Underwriter - Senior Associate remote type Flex locations Washington, DC time type Full time job requisition id JR2615 Playing an essential role in the U.S. economy, Fannie Mae is foundational to housing finance. Here, your expertise can help fuel purpose-driven innovation that expands access to homeownership and affordable rental housing across the country. Join Fannie Mae to grow your career and help people find a place to call home. Job Description As a valued colleague on our Low-Income Housing Tax Credit (LIHTC) team, you will provide expert advice on overseeing customer network development and customer support activities, as well as supporting customer engagement opportunities. Since restarting its LIHTC platform in 2018, Fannie Mae has been a significant investor in proprietary and multi-investor funds. As a valued contributor on our dynamic team, you will help the LIHTC team originate new proprietary and multi-investor fund LIHTC investments through our syndicator partners. Additionally, you will be responsible for assigned operational activities for the team with the help of executives and staff managers. THE IMPACT YOU WILL MAKE The LIHTC Underwriter, Senior Associate role will offer you the flexibility to make each day your own, while working alongside people who care so that you can deliver on the following responsibilities: - Develop customer relationships by working with the LIHTC team’s Senior Director, Director, Advisors and syndicator partners to communicate investment parameters, manage pipeline, and screen, model, price and negotiate letters of intent (LOIs) for multifamily LIHTC investments. - Support the LIHTC team’s business activities by assisting with the underwriting and closing of proprietary and multi-investor fund investments, including negotiating proprietary fund agreements, under the direction of the Senior Director, Director and Advisors. Also periodically assist the Head of Underwriting with the underwriting and closing of lower tier proprietary investments. - Identify and assess the risk profile of LIHTC investments to ensure risk is mitigated and objectives are met within appropriate credit, investment and regulatory guidelines. - Coordinate with internal and external teams to develop key milestones to achieve a seamless execution of LOIs and secure investments. - Assist the Senior Director, Director, Chief Operating Officer and Vice President in managing and updating processes related to internal stakeholders such as multifamily legal, risk, operations, finance, accounting and audit. - Partner with management to recommend business solutions based on analysis of internal and market data. - Actively participate on special projects as needed. - Travel on a limited basis to visit prospective investments and markets. THE EXPERIENCE YOU BRING TO THE TEAM Minimum Required Experience - 2 years of relevant experience with a track record underwriting LIHTC proprietary fund investments while maintaining product and credit quality. - Demonstrated experience in modeling and structuring LIHTC investments and managing critical projects, as well as tight and changing timelines. - Skilled in managing multiple and competing priorities to help the Senior Director and Director maintain a robust pipeline of prospective investments shown by syndicator partners. - Highly motivated self-starter with good attention to detail. - Team player with excellent interpersonal skills who is energized by working in a collaborative, dynamic and evolving team environment. - Strong analytical, verbal, written and presentation communication skills. - Ability to influence through negotiating, persuading others, facilitating meetings, and resolving conflict. - Ability to successfully manage and engage stakeholders, customers, and vendors and build relationship networks. - Experience gathering accurate information to clearly explain concepts and answer critical questions. - Proven ability to work respectfully and cooperatively with individuals across diverse functional areas to achieve shared goals. - Skilled in Microsoft Office suite products with particular focus on Excel, Word and PowerPoint. - Curiosity and adaptability learning and responsibly applying new techniques, including artificial intelligence, to reimagine how we work Desired Experience - Bachelor’s degree or equivalent. - Experience with equity or debt portfolio management software/systems such as MRI, Salesforce, and Yardi. - Ability to navigate multiple systems, manage data and create reports. Multifamily Family Customer Engagement - Customer and Partner Management - Senior Associate #LI-NL1 - Hybrid Qualifications Education: Bachelor's Level Degree (Required) The future is what you make it to be. Discover compelling opportunities at Fanniemae.com/careers. For most roles, employees are expected to work onsite on a regular basis at their designated office location. In-office work cadence is determined by your manager. Proximity within a reasonable commute to your designated office location is preferred unless the job is noted as open to remote. Fannie Mae is an equal opportunity employer and considers qualified applicants for employment without regard to race, color, religion, sex, national origin, disability, age, sexual orientation, gender identity/gender expression, marital or parental status, or any other protected factor. Fannie Mae is committed to providing reasonable accommodations to qualified individuals with disabilities who are employees or applicants for employment, unless to do so would cause undue hardship to the company. If you need assistance using our online system and/or you need a reasonable accommodation related to the hiring/application process, please complete this form. The hiring range for this role is set forth below. Final salaries will generally vary within that range based on factors that include but are not limited to, skill set, depth of experience, certifications, and other relevant qualifications. This position is eligible to participate in a Fannie Mae incentive program (subject to the terms of the program). As part of our comprehensive benefits package, Fannie Mae offers a broad range of Health, Life, Voluntary Lifestyle, and other benefits and perks that enhance an employee's physical, mental, emotional, and financial well-being. See more here. Requisition compensation: 96000 to 124000

• Define a unified strategy spanning self-serve education, scaled training, and customer-facing team enablement. • Build a multi-year roadmap tied to adoption and retention outcomes. • Establish metrics that demonstrate education's impact on adoption, retention, support deflection, and Services revenue. • Represent customer education and enablement in executive and cross-functional forums. • Lead Help Center, knowledge base, onboarding, and in-app education strategy. • Define content architecture, editorial standards, and quality benchmarks. • Oversee the global strategy for live and on-demand customer training. • Manage LMS strategy, governance, and long-term evolution. • Coordinate the enablement of customer-facing teams on platform and product knowledge. • Partner with Services and CS leadership on scoping, renewals, and expansion. • Drive cross-functional launch-readiness standards so every release ships education-ready. • Guide the technology and AI roadmap for customer education and enablement.

Role Description As the Global head of Risk GTM Lead, you will play a pivotal role in driving the execution of go-to-market (GTM) strategies for the Risk portfolio. Reporting directly to the Global Head of CISO Solutions, you will act as a key contributor to business growth, customer engagement, and operational excellence. This role is ideal for a results-oriented professional with a passion for customer-centric innovation and cross-functional collaboration. - Engage directly with strategic customers to understand needs, drive adoption, and ensure satisfaction. - Serve as a practitioner and advocate for customer-centricity, maintaining feedback loops to inform GTM decisions. - Collaborate with the Risk BU to develop and refine GTM strategies, including influencing pricing, packaging, and market positioning. - Integrate customer and market feedback to continuously improve offerings. - Architect and design sales motions that maximize pipeline generation, progression, and new net annual contract value (NNACV). - Work closely with sales, product, and marketing teams to ensure cohesive execution. - Elevate, simplify, and transform solution messaging in partnership with Product Solution Marketing (PSM), ensuring clarity and impact across all channels. - Drive integration of GTM initiatives across GPC, CEG, PSM, Industry, and GTM Field Practitioners to ensure scalability and performance tracking. - Measure, analyze, and refine business KPIs and BU OKRs to track performance and drive continuous improvement. - Provide actionable insights to leadership and stakeholders. - Stay ahead of market trends, competitive shifts, and emerging technologies to inform GTM strategy and positioning. - Represent the company at industry events, panels, and executive forums. - Foster a culture of innovation, collaboration, and continuous improvement. Qualifications - 7+ years of experience in GTM strategy, business operations, or customer success, with at least 3 years in a senior role. - Proven track record of driving strategic initiatives and operational execution in complex, matrixed environments. - Deep experience engaging with senior stakeholders and influencing executive decision-making. - Strong analytical, communication, and storytelling skills. - Experience in SaaS, cloud, or enterprise technology preferred. - MBA or equivalent advanced degree is a plus. Benefits - Senior leader level visibility and impact. - A dynamic, collaborative environment with top-tier talent. - Competitive compensation and benefits. - Opportunities for growth and leadership across the organization.