• Responsible for leadership and/or technical oversight of an assigned Information Technology (IT) segment within the organization • Creating and rolling out policies and procedures associated with assigned IT segment • Act as point of contact and full accountability for high degree of redundancy and reliability of assigned IT segment • Identifies best practices for service offerings of IT segment • Maintains in-depth knowledge of departmental workflows • Responsible for vendor management, including contract negotiations, invoice reconciliation, release updates, issues lists and new product evaluations • Reviews work of lower level personnel to ensure satisfaction of service offerings • Performs personnel review and evaluation function for salary administration, training and promotion • Prepares periodic budget and adherence for the department • Monitors compliance with Information Systems procedures and policies • Presents issues and concerns to IT leadership along with potential solutions when appropriate • Works with departmental and division management to develop and implement Information Technology strategies • Establish and monitor operational KPIs, including productivity standards • Develops and administers IT budget for responsible area • Practices fiscally sound budget management to ensure spending is held to allocated funds

Role Description The Lead, Tech Portfolio Management is responsible for aligning the Tech portfolio and demand with enterprise strategy in close partnership with business and Tech leadership. This role serves as a strategic advisor to senior executives, driving the development of portfolio roadmaps, managing cross-team dependencies, and ensuring effective execution across initiatives. The position provides leadership in prioritizing investments, optimizing delivery performance, and governing financials, including Total Cost of Ownership (TCO) and resource allocation. This role addresses complex portfolio challenges, delivers actionable insights through metrics and reporting, and ensures initiatives are executed in alignment with scope, timeline, cost, and value outcomes. This is a primarily remote (work-from-home) position. However, candidates must be based in or near one of the following primary markets: Louisville, Nashville, Tampa, Fort Lauderdale, or Dallas. Secondary consideration may be given to candidates located in Chicago or Washington, D.C. Key Responsibilities: - Align portfolio priorities with organizational strategy in partnership with business and Tech leaders, including Lean Portfolio Management (LPM) expectations. - Serve as a trusted advisor to Tech Partners on Segment strategy, including roadmap, risks, and dependencies. - Develop and maintain integrated portfolio roadmaps and delivery plans across teams, ensuring alignment on scope, timing, and outcomes. - Prioritize initiatives based on strategic value, funding, capacity, and evolving business needs. - Manage cross-team dependencies and monitor delivery performance (e.g., actual vs. forecast, story points), identifying risks and driving corrective actions. - Lead monthly portfolio reviews to evaluate execution, ensuring alignment to scope, schedule, cost, and value delivered. - Track and report on delivery trends, financial performance, and initiative changes, including scope and timeline adjustments. - Assess vendor performance and impacts to delivery milestones and portfolio outcomes. - Communicate insights and recommendations to senior leadership, while fostering continuous improvement and adaptability across the portfolio. Qualifications - Bachelor’s degree in Information Technology, Business, or a related field. - 8+ years of experience in IT, portfolio management, or related technical environments. - Proven experience leading projects or programs, driving execution across multiple concurrent initiatives. - Strong expertise in Agile ways of working, including Lean Portfolio Management (LPM) principles. - Hands-on experience with portfolio management tools, including Jira Align. - Experience managing large-scale, highly visible programs involving multiple project teams. - Advanced analytical and organizational skills, with ability to synthesize complex data into actionable insights and reporting. - Excellent communication and presentation skills, with experience influencing senior leadership and stakeholders. Requirements - MBA or other advanced degree. - SAFe Lean Portfolio Management Certification. - Background in insurance or healthcare industry portfolio management. Benefits - Health benefits effective day 1. - Paid time off, holidays, volunteer time and jury duty pay. - Recognition pay. - 401(k) retirement savings plan with employer match. - Tuition assistance. - Scholarships for eligible dependents. - Parental and caregiver leave. - Employee charity matching program. - Network Resource Groups (NRGs). - Career development opportunities.

• Translate program strategy into integrated timelines, milestones, and deliverables, ensuring coordination across all contributing functions • Provide Project Management expertise and support to advance Kyverna’s novel engineered T cell therapy programs • Manage one or more highly complex R&D programs and/or high-profile partnerships • Results-oriented accountability for achievement of program timeline and deliverables • Effectively communicate with project team members, Senior Leadership Team, Functional Heads, and key stakeholders • Track and monitor key milestones and decision points to drive delivery of project objectives • Contribute to PMO LT to develop tools for project governance and program timelines, as well as the communication of program KPIs, risks and achievements • Manage the interfaces between functional areas and ensure effective handoff and communication between department functions to execute on important project milestones • Lead cross-functional program management activities supporting autoimmune clinical development programs. • Develop and maintain integrated clinical development plans, timelines, milestones, budgets, and risk management strategies across multiple functional areas. • Drive execution and alignment across Clinical Development, Clinical Operations, Medical Affairs, Biometrics, Safety/Pharmacovigilance, Regulatory Affairs, Manufacturing, and Quality. • Partner with Clinical and Medical leadership to support development strategy, indication prioritization, and lifecycle planning for assigned programs. • Ensure program activities support regulatory milestones including INDs, protocol amendments, global health authority interactions, and potential BLA/MAA submissions. • Partner with Clinical Operations to proactively identify enrollment, operational, and site-performance risks and implement mitigation strategies. • Ensure seamless coordination between clinical and CMC activities supporting cell therapy manufacturing, supply planning, patient scheduling, and treatment logistics. • Facilitate governance meetings, cross-functional team meetings, and executive program reviews. • Collaborate with Clinical Research Scientists and Medical Directors on protocol strategy, clinical endpoints, efficacy measures, biomarkers, and patient-reported outcomes relevant to autoimmune studies. • Support competitive intelligence activities and maintain awareness of evolving autoimmune treatment landscapes, clinical trial designs, and emerging therapies. • Partner with Regulatory and Medical Writing teams to support preparation of briefing documents, regulatory submissions, investigator brochures, and clinical study reports. • Establish and maintain program dashboards, KPIs, risk registers, and governance frameworks to ensure transparency and accountability. • Drive continuous improvement of program management processes, tools, and reporting capabilities. • Support budget forecasting, scenario planning, and resource prioritization across clinical programs. • Mentor and develop program management staff and contribute to building scalable development operations infrastructure.

• Maintain and manage the PCI DSS scope, including periodic scoping exercises and CDE boundary reviews • Coordinate and conduct an annual external assessment with a QSA • Define and manage the vendor/third-party assessment process for entities that handle or touch cardholder data (SAQ collection, contractual requirements) • Ensure systems, applications and internal processes comply with latest PCI DSS requirements • Work cross-functionally to identify, mitigate and manage security risks related to payment card data • Provide status reports for findings and provide relevant recommendations for remediation • Own the PCI DSS impact assessment process for new products, features, and infrastructure changes, providing sign-off before launch • Create and maintain relevant documentation and policies as required by PCI DSS • Facilitate cross functional team coordination to ensure controls are operating effectively and help identify areas for improvement • Develop and deliver PCI DSS awareness training for relevant internal teams • Leverage automated compliance tooling to monitor control health, track remediation, and generate reporting for leadership • Own preparation of PCI DSS status reporting for management and audit committee meetings