• Translate program strategy into integrated timelines, milestones, and deliverables, ensuring coordination across all contributing functions • Provide Project Management expertise and support to advance Kyverna’s novel engineered T cell therapy programs • Manage one or more highly complex R&D programs and/or high-profile partnerships • Results-oriented accountability for achievement of program timeline and deliverables • Effectively communicate with project team members, Senior Leadership Team, Functional Heads, and key stakeholders • Track and monitor key milestones and decision points to drive delivery of project objectives • Contribute to PMO LT to develop tools for project governance and program timelines, as well as the communication of program KPIs, risks and achievements • Manage the interfaces between functional areas and ensure effective handoff and communication between department functions to execute on important project milestones • Lead cross-functional program management activities supporting autoimmune clinical development programs. • Develop and maintain integrated clinical development plans, timelines, milestones, budgets, and risk management strategies across multiple functional areas. • Drive execution and alignment across Clinical Development, Clinical Operations, Medical Affairs, Biometrics, Safety/Pharmacovigilance, Regulatory Affairs, Manufacturing, and Quality. • Partner with Clinical and Medical leadership to support development strategy, indication prioritization, and lifecycle planning for assigned programs. • Ensure program activities support regulatory milestones including INDs, protocol amendments, global health authority interactions, and potential BLA/MAA submissions. • Partner with Clinical Operations to proactively identify enrollment, operational, and site-performance risks and implement mitigation strategies. • Ensure seamless coordination between clinical and CMC activities supporting cell therapy manufacturing, supply planning, patient scheduling, and treatment logistics. • Facilitate governance meetings, cross-functional team meetings, and executive program reviews. • Collaborate with Clinical Research Scientists and Medical Directors on protocol strategy, clinical endpoints, efficacy measures, biomarkers, and patient-reported outcomes relevant to autoimmune studies. • Support competitive intelligence activities and maintain awareness of evolving autoimmune treatment landscapes, clinical trial designs, and emerging therapies. • Partner with Regulatory and Medical Writing teams to support preparation of briefing documents, regulatory submissions, investigator brochures, and clinical study reports. • Establish and maintain program dashboards, KPIs, risk registers, and governance frameworks to ensure transparency and accountability. • Drive continuous improvement of program management processes, tools, and reporting capabilities. • Support budget forecasting, scenario planning, and resource prioritization across clinical programs. • Mentor and develop program management staff and contribute to building scalable development operations infrastructure.

• Maintain and manage the PCI DSS scope, including periodic scoping exercises and CDE boundary reviews • Coordinate and conduct an annual external assessment with a QSA • Define and manage the vendor/third-party assessment process for entities that handle or touch cardholder data (SAQ collection, contractual requirements) • Ensure systems, applications and internal processes comply with latest PCI DSS requirements • Work cross-functionally to identify, mitigate and manage security risks related to payment card data • Provide status reports for findings and provide relevant recommendations for remediation • Own the PCI DSS impact assessment process for new products, features, and infrastructure changes, providing sign-off before launch • Create and maintain relevant documentation and policies as required by PCI DSS • Facilitate cross functional team coordination to ensure controls are operating effectively and help identify areas for improvement • Develop and deliver PCI DSS awareness training for relevant internal teams • Leverage automated compliance tooling to monitor control health, track remediation, and generate reporting for leadership • Own preparation of PCI DSS status reporting for management and audit committee meetings

• Proactively examines, experiments, and measures improvements to design operational model, processes, and ways of working (e.g. automating tasks, improving workflows, developing repeatable methodologies), working closely with the Design Operations team and leadership to balance competing priorities to effectively and efficiently deliver impact. • Possesses a proven track record of collaborating with and influencing product design leadership and cross-functional partners. • Strong capacity for leading change, dealing with ambiguity and proactively recommending, driving, and measuring operational process improvements, from inception of solution to delivery. Requires minimal to no supervision. • Develops and implements structured communications plan for programs. Owns driving towards clarity for initiatives, including proactively anticipating questions to address and developing clear responses. • Oversees and manages program status and health, mitigating risks, removing barriers efficiently and effectively to support team, and escalating when necessary. • Assesses changes in scope and impact to budget and timeline, communicating effectively with both internal and external partners. • Provides status reports and timelines to cross-functional leadership teams and drive clear action towards goals and objectives. • Defines and measures impact of program both quantitively and qualitatively— sharing best practices to strengthen design operations. • Facilitate collaboration and continuous improvement of processes and methodologies to strengthen ways of working across cross-functional teams • Evaluate & implement the industry’s best tools with other design program managers, researchers, designers and cross-functional partners to solve our growing need to collaborate globally. • Proactively seek to turn ambiguous opportunities into tangible initiatives and structured projects. • Highly organized with strong writing, influencing skills and impeccable attention to detail.

• Lead and work with a talented and high-performing team on challenging projects. • Effectively manage complex scientific/research projects. • Manage the budget and juggle multiple priorities. • Organize processes and oversee successful execution from concept to deliverables. • Coordinate among management and technical professionals as the ultimate leader of the project and the consortium.