• Considered as the primary point of contact for the investigative site • High level of competency or experience in providing contextual information on the clinical trials, connects stakeholder to the investigative sites and strengthens AbbVie’s positioning • Aligns, trains and motivates the site staff and principal investigator on the goals of the clinical trial program, protocol and patient treatment principles for the trial ensuring a trusted partnership • Conducts site evaluation, site training, routine, and site closure monitoring activities with compliance to the protocol and monitoring plans, in accordance with applicable regulations, Good Clinical Practices (GCPs), ICH Guidelines, AbbVie Standard Operating Procedures (SOPs), and quality standards, ensuring safety and protection of study subjects • Advanced understanding of site engagement and ability to customize site engagement strategy for assigned study (ies) • Gather local/site insights and utilize site engagement tools such as the Customer Relationship Management (CRM) tool, to report/track progress and measure impact of that strategy • Advanced level of competency connecting the study protocol, scientific principles and clinical trial requirements to the day-to-day clinical trial execution activities • Evaluate and ensure effective recruitment and retention techniques/plans based on the patient disease journey • Develop solid knowledge of therapeutic area, asset and clinical landscape / patient journey to enable successful patient recruitment and overall protocol compliance • Possesses experienced level of competency to mentor and train less experienced CRAs on various aspects of work and provides input into their development • May participate in global/local task forces and initiatives • Responsible for activities as assigned by manager • Responsible for continuous risk-assessment proactively, and in collaboration with Central Monitoring team, monitor activities conducted by clinical sites to detect early overall study performance or patient safety issues • Advanced ability to think critically to resolve site risk signals while having robust understanding of site processes to drive study execution • Ensures preventative and corrective action plans are put into place, as needed, to mitigate risk and promote compliance using a customer centric approach • Identifies, evaluates and recommends new/potential investigators/sites on an on going basis • Ensures quality of data submitted from study sites and assures timely submission of data, including appropriate reporting and follow-up for all safety events by site personnel • Ensures audit and regulatory inspection readiness at assigned clinical site at all times • Manages investigator payments as per executed contract obligations, as applicable

• Monitors clinical trials and observational studies ensuring protocol adherence, managing site activities, and overseeing data collection and integrity. • Ensures sites are conducting the study(ies) and reporting study data as required by applicable regulations and guidelines, and sponsor requirements. • Mentors and trains junior level CRAs. • Performs remote and on-site monitoring in accordance with project specific timelines. • Completes travel scheduling in accordance with project specific and UBC travel policy. • Submits expense reports within UBC requirements. • Attends project team meetings, department meetings and one-to-one meetings with the manager. • Completes site monitoring reports and letters per UBC and/or sponsor SOPs requiring minimal corrections. • Ensures follow-up of site issues and action items per UBC/sponsor timelines. • Enters site visits, site monitoring reports, follow-up letter sent date and site contacts into UBC’s Clinical Trial Management System (CTMS). • Monitors within Electronic Data Capture (EDC) data entry, if applicable, and assists sites with electronic Case Report Form (eCRF) resolution. • Reviews Investigator Site File and performs Investigational Product reconciliation. • Maintains regular contact with assigned sites per study requirements. • Completes all SOP review, training assessments and documentation within requested timelines. • Assists Project Manager (PM) and management team by mentoring, training and assessing junior CRAs. • Assists with preparation and/or delivery of presentations for UBC CRA training, departmental training and/or sponsor specific training. • Assists PM and/or Lead CRA with additional tasks as needed. • Completes Site Management and Monitoring activities in accordance with project specific plans and timelines. • Assists with other duties as assigned, which may align with other departments at UBC.

Title: Research Assistant I Location: East Lansing, Michigan, United States Work Type: Hybrid, Full Time Job ID: 1144172 Job Description: - Small Animal Clinical Sciences 10046764 - Area of Interest: Research/Scientific - Area of Interest: Veterinary/Animal Care - Full Time/Part Time: Full Time (90-100%) - Group: Administrative Professionals- AP - Remote Work: Remote-Friendly - Union/Non-Union: Union Position Summary The Hume and Mansfield Labs study DNA damage and cancer, and the links between the gut and chronic disease. The position starts in Summer 2026 and may be renewed for a second year, based on funding availability. The Research Assistant will contribute to data collection, processing, visualization, analysis, interpretation, and dissemination of results. The position will also include other experimental and research support. Minimum Requirements Knowledge equivalent to that which normally would be acquired by completing a four-year college degree program in Biomedical Science or other related science fields; one to three years of related and progressively more responsible or expansive work experience in standard laboratory procedures and safety requirements and performing analytical and research techniques in an area related to research being performed; Will require Basic computer skills (MS Office, Email, WWW searches and data analysis programs; or an equivalent combination of education and experience. Desired Qualifications - Must be able to work independently as well as in a team environment while paying close attention to details and meeting concurrent deadlines regularly - Excellent oral and written communication skills - Strong attention to detail - Strong interpersonal skills - Strong commitment to experimental goals while using sound judgment - Experience working with laboratory mouse colonies and animal handling - Will be required to take the necessary training courses at MSU in animal handling and care, chemical waste and other general laboratory safety courses - Research experience using basic molecular techniques including but not limited to but not limited to protein, RNA, and DNA extraction; real-time PCR; mammalian cell culture; cell-function assays; ELISA; flow cytometry; immunofluorescence staining and microscopy Work Hours STANDARD 8-5 Description of End Date This is an off date position funded for one year from date of hire with possible extension contingent upon funding renewal. Summary of Health Risks Works with animals and unfixed animal tissue. Remote Work Statement MSU strives to provide a flexible work environment and this position has been designated as remote-friendly. Remote-friendly means some or all of the duties can be performed remotely as mutually agreed upon.

• Coordinate the identification, feasibility assessment, and selection of investigators and sites to undertake the trial. • Complete all monitoring activities per the Monitoring Plan along with completing monitoring visit reports, accurately and within the predetermined timeframe. • Prepare, plan, organize, and conduct site evaluation visits and report on these visits to assist in site selection. • Prepare, submit, and/or liaise with regulatory specialist colleagues, regarding the preparation of regulatory packages, importation/exportation requirements, and updates of Ethics Committee packages. • Negotiate site budgets, coordinate for site contract execution, track invoicing, and ensure timely site payments. • Prepare, plan, organize, and conduct site initiation visits. • Develop and maintain appropriate monitoring tools and project-specific documents. • Motivate and train investigators to ensure that the trial site personnel have a good understanding of the protocol, investigational product, and requirements of the trial so they can fulfill their obligations to conduct the trial accurately and to deadlines. • Collect, review, and approve essential documents from trial sites, to ensure quality and compliance, and code documents for Trial Master File (TMF) filing. • Reconcile contents of in-house TMF and site’s Investigator Site Files. • Coordinate distribution, tracking, handling, and destruction of investigational product and other trial supplies per site/trial requirements. • Maintain trial information using the clinical trial management system and any other tracking and reporting tools for the trial. • Support strategies to boost recruitment efforts.