Role Description As VP of Growth, you'll be charged with identifying, building the business case for, and driving new revenue-generating initiatives and partnerships. Over the next 3–5 years, this role is expected to contribute $25–50M in new revenue to the business. This is fundamentally a new business development role in the truest sense — less "manage a sales team," more "find the opportunity, build the case, go get it done." What you'll do: - Identify and evaluate new growth initiatives, partnerships, and market opportunities - Build rigorous business cases and ROI/financial analyses to prioritize and pitch initiatives - Lead and execute on selected initiatives from concept through revenue generation - Develop and negotiate strategic partnerships — potentially including technology partnerships, OEM relationships, or white-label arrangements where outside technology is packaged and resold - Operate as a strategic, analytical thinker as much as a relationship-driven dealmaker - Work closely with executive leadership as a key driver of the company's growth strategy Qualifications - Strong analytical/business case background — MBA or MBA-equivalent skill set preferred (financial modeling, ROI analysis, strategic case-building) - A track record of building and closing new business development initiatives or strategic partnerships — not just managing an existing book of business - Experience in technology, software, marketplace, or platform businesses; aviation industry experience is not required - Ideally, experience structuring partnership, OEM, or white-label deals that drove meaningful new revenue - Comfort operating in ambiguity — this role has the scope to grow significantly as the company scales Benefits - A genuinely new, high-impact role with room to define and expand its own scope - Direct line of sight to company leadership - Opportunity to shape a growth function from the ground up rather than inherit an existing playbook - Strong, competitive compensation package (base + bonus + potential long-term incentive)

• Lead the overall clinical development strategy for oncology programs with primary focus on cholangiocarcinoma and hepatocellular carcinoma from early development through late-stage and registration-enabling studies • Develop and execute integrated clinical development plans aligned with regulatory objectives including study protocol design, execution, and data analysis/interpretation, in conjunction with other relevant functional leaders • Direct study design, protocol development, and execution for Phase 1-3 clinical trials, including pivotal registrational cancer studies • Provide expert oversight of clinical data analysis and interpretation, ensuring data are robust, clinically meaningful, and suitable to support regulatory decision-making • Contribute to pipeline strategy and diligence for new internal and external oncology opportunities, providing senior clinical and regulatory development input • Serve as a clinical development lead for global regulatory interactions, working in close partnership with Regulatory Affairs to define strategy and messaging • Lead and actively participate in meetings with regulatory agencies (e.g., FDA, EMA, MHRA), including scientific advice, End-of-Phase, pre-NDA/BLA, and ad hoc regulatory interactions, from a clinical development perspective • Provide senior clinical oversight and direction for the review of NDA and/or BLA clinical components, including clinical summaries, integrated analyses, and supporting study documentation • Lead the clinical development contribution to responses to health authority questions, including written responses to information requests, major review questions, and post-submission clarifications • Ensure that clinical strategy, trial design, and data presentation are aligned with evolving regulatory guidance and agency feedback throughout the product lifecycle • Ensure the quality, consistency, and regulatory readiness of all clinical documents, including Investigators’ Brochures, protocols, CSRs, safety narratives, and submission-critical documents • Provide senior scientific and clinical input into study-related documentation, including ICFs, CRFs, SAPs, clinical pharmacology analysis plans, and data interpretation narratives

• The Area Vice-President, Sales is a first-line sales leader responsible for launching the NEXCHANGE KIT, Osteal’s lead investigational therapy for periprosthetic joint infection, which has received FDA Breakthrough Therapy, Fast Track, Orphan Drug, and Qualified Infectious Disease designations. This role builds the regional Account Manager team, owns launch execution, surgeon adoption, and translates national strategy into account-level plans. • The AVP partners across Marketing, Market Access, Medical Affairs and Training to deliver an aligned go-to-market strategy and serves as the voice of the field in shaping commercial strategy. • The role demands an entrepreneurial builder with prior launch leadership, deep credibility in orthopedics and the operating room, and the resilience to drive results in a fast-moving, pre-commercial environment. As Osteal builds the commercial organization, this leader will have the opportunity to shape the future field structure, including recruiting and developing District Managers, and growing into broader second-line leadership responsibilities over time.

• Recruit, develop, and lead a high-performing team of Account Managers. • Provide field-based coaching through joint calls and in-hospital support. • Own regional sales forecasting, pipeline management, and performance reporting: conduct ongoing performance management and provide input on compensation plan design and quota setting. • Translate national strategy into actionable regional, territory and account level plans aligned to launch objectives. • Drive regional launch execution including site activation, surgeon adoption, and achievement of quarterly revenue and unit goals. • Identify, develop, and cultivate regional KOLs and centers of excellence in orthopedic infection management. • Partner cross-functionally with Marketing, Market Access, Medical Affairs, Training and Operations to drive aligned execution. • Serve as the voice of the field, bringing insights that inform strategy and decision-making. • Ensure team adherence to all applicable laws, regulations, and company policies.