• Build, manage, and develop a team of 15+ data scientists across Growth, Risk, Core Product and business expansion to help Mercury make better decisions informed by data. • Influence data analytics and data engineering culture and rigor across different levels, from executives to individual product and operations teams. • Guide the strategy, architecture, and tooling of Mercury’s data infrastructure to enable the entire company to use data effectively.

• The Associate Director/ Director of Health Economics and Outcomes Research (Early Stage Pipeline) will be responsible for defining and executing early evidence generation strategies and deliverables across multiple programs. • Support HEOR/COA endpoint strategy from Phase 1 to 3 clinical studies ensuring inclusion of patient-centric, clinically meaningful, and economically relevant outcomes. • Contribute to commercial and global market access strategy to influence trial designs that meet expectations from multiple stakeholders. • Lead development of HTA-grade cost-effectiveness and budget-impact models to support early decision-making, identify value drivers, pricing, value dossiers, and individual country-specific submissions. • Partner with Global/US Market Access and Regulatory to ensure pivotal studies capture relevant endpoints.

• Own the development and execution of integrated U.S. payer strategies across the Ionis commercial portfolio. • Establish long-range access vision, coverage objectives, and reimbursement strategies aligned with brand and corporate priorities. • Shape and implement enterprise-level access frameworks that can scale across current and future launches. • Identify, quantify, and proactively mitigate access risks and reimbursement barriers. • Provide forward-looking analysis of payer landscape shifts, policy changes, and competitive access dynamics. • Lead U.S. access readiness strategy from pre-launch planning through lifecycle optimization. • Oversee development of payer-facing and field access materials. • Ensure alignment of clinical and economic evidence generation with payer requirements in partnership with HEOR and Medical Affairs. • Influence economic modeling, value frameworks, and budget impact strategies to support coverage negotiations. • Oversee pull-through strategies to accelerate coverage adoption and minimize patient access friction. • Lead and develop a high-performing U.S. Value & Access organization and drive team execution to achieve measurable access outcomes. • Establish clear strategic priorities and ensure alignment of resources against enterprise objectives. • Build scalable capabilities to support portfolio expansion and future product launches. • Foster a culture of collaboration, accountability, and continuous improvement. • Partner closely with Brand, Medical Affairs, HEOR, Regulatory, Government Affairs, Pricing, Field Access, and Sales leadership to ensure cohesive execution. • Integrate payer insights into brand planning, evidence strategies, and lifecycle investment decisions. • Provide executive-level recommendations to senior leadership on reimbursement strategy and payer engagement.

• Lead end-to-end implementation efforts from contract execution through go-live and transition to steady-state operations • Drive the transformation and standardization of implementation methodologies, tools, templates, and governance models • Identify and implement improvements to reduce implementation cycle time, risk, and cost while improving quality and client satisfaction • Establish scalable implementation frameworks that support growth across multiple states and programs • Partner closely with Sales leadership to manage the implementation pipeline, demand forecasting, and delivery readiness • Serve as a senior implementation leader for key clients, ensuring alignment on scope, timelines, risks, and success criteria • Coordinate cross-functional teams including Technology, Data Management, Operations, Analytics, Product, and Shared Services • Lead, mentor, and develop implementation managers, project managers, and delivery staff • Establish implementation governance, escalation paths, and delivery assurance processes • Monitor implementation performance through KPIs, milestones, and risk indicators