• Provide strategic oversight and end-to-end operational leadership for global Phase 3 asthma studies and related development activities. • Translate program strategy into comprehensive, executable operational plans aligned with regulatory, scientific, and corporate objectives. • Accountable for study timelines, budgets, resource allocation, quality metrics, and overall delivery. • Lead scenario planning, risk forecasting, and mitigation strategies at the program level. • Partner with Clinical Development leadership to inform portfolio-level planning and decision-making. • Directly manage and develop Clinical Operations staff (e.g., Clinical Trial Leads and/or Clinical Trial Managers). • Recruit, hire, onboard, and retain top talent to support late-stage clinical development. • Set performance expectations, conduct evaluations, provide coaching, and support career development. • Build a culture of accountability, collaboration, and operational excellence. • Lead multidisciplinary study teams across Clinical Operations, Data Management, Biostatistics, Safety, Regulatory, Medical, Quality, and CMC. • Act as a primary point of accountability across internal stakeholders, CRO partners, and external vendors. • Enable effective decision-making, timely escalation, and transparent communication across teams. • Oversee global study startup, site strategy, enrollment execution, monitoring approaches, and patient engagement initiatives. • Ensure compliance with ICH-GCP, global regulatory requirements, and internal SOPs. • Provide oversight of study budgets, vendor performance, and quality metrics. • Establish performance metrics and drive continuous improvement across external partnerships. • Lead inspection readiness strategy and support regulatory inspections. • Drive proactive issue identification, risk management, and CAPA oversight. • Contribute to Clinical Operations strategy, infrastructure development, and process optimization. • Champion innovation in trial execution, including digital tools, decentralized approaches, and patient-focused strategies. • Share best practices and help define standards across the clinical operations organization.

City/State Virginia Beach, VA Work Shift First (Days) Overview: Sentara is hiring a Patient & Digital Experience Domain Architect This position is fully remote. Overview We are seeking an experienced Patient & Digital Experience Domain Architect to join our Clinical Systems Domain Architecture team. This highly visible role is responsible for shaping and advancing the digital front door and end-to-end patient experience across Sentara. The Architect will partner closely with executive, clinical, operational, and technical leaders to design and drive a cohesive, patient-centered technology strategy that improves access, engagement, and experience. This role focuses on thoughtful architectural design across scheduling, registration, referrals, authorizations, communications, and digital engagement tools - ensuring solutions are intuitive, scalable, and aligned with organizational goals. About the Role The Patient & Digital Experience Domain Architect supports enterprise architecture strategy by designing and governing domain-level architecture and driving the long-term technology roadmap for patient-facing and digital experience platforms. The role provides architectural leadership and solution guidance, helping ensure digital experiences reduce friction, improve access, and create a consistent experience for patients across all channels. Domains & Technologies in Scope Epic Patient Experience Platforms : Welcome Interconnect Digital Front Door Capabilities : Online scheduling and registration Referrals and prior authorizations Patient communications and outreach Chatbots and conversational tools AI-assisted digital workflows Integration & Enablement : FHIR, APIs, interoperability patterns Experience continuity across systems and touchpoints Key Responsibilities Lead domain-level architecture strategy for Patient and Digital Experience technologies Design and drive the digital front door roadmap, focused on access, engagement, and patient experience Architect seamless workflows across scheduling, registration, referrals, and authorizations Provide architectural guidance for MyChart, chatbots, AI-assisted tools, and digital engagement platforms Partner with executive, clinical, operational, and technical leaders to align digital experience strategy with enterprise goals Serve as a contributor in Architecture Review Board (ARB) discussions related to patient-facing technologies Establish standards and patterns that promote usability, accessibility, consistency, and scalability Evaluate emerging technologies that improve patient self-service, communication, and personalization Required Qualifications Preferred Qualifications Background with Epic eMPA and prior authorization workflows Experience with additional Epic digital tools such as Welcome and Interconnect Demonstrated experience designing or improving digital front door capabilities Familiarity with chatbots, conversational interfaces, or AI-assisted digital tools Knowledge of FHIR, APIs, and interoperability patterns Experience contributing to enterprise architecture governance or participating in ARB Exposure to accessibility, usability, or service design principles Talroo-IT . Benefits: Caring For Your Family and Your Career • Medical, Dental, Vision plans • Adoption, Fertility and Surrogacy Reimbursement up to $10,000 • Paid Time Off and Sick Leave • Paid Parental & Family Caregiver Leave • Emergency Backup Care • Long-Term, Short-Term Disability, and Critical Illness plans • Life Insurance • 401k/403B with Employer Match • Tuition Assistance – $5,250/year and discounted educational opportunities through Guild Education • Student Debt Pay Down – $10,000 • Reimbursement for certifications and free access to complete CEUs and professional development • Pet Insurance • Legal Resources Plan • Colleagues may have the opportunity to earn an annual discretionary bonus if established system and employee eligibility criteria is met Sentara Independence provides quality outpatient services to the surrounding community. The facility includes an ambulance-accessible emergency room that is supported by board-certified physicians. Sentara Independence houses state-of-the-art medical equipment and highly-skilled physicians and staff.  Sentara Independence is now an extension of the quality services at Sentara Virginia Beach General Hospital including advanced imaging and physical therapy. Sentara Health is an equal opportunity employer and prides itself on the diversity and inclusiveness of its close to an almost 30,000-member workforce. Diversity, inclusion, and belonging is a guiding principle of the organization to ensure its workforce reflects the communities it serves. In support of our mission “to improve health every day,” this is a tobacco-free environment. For positions that are available as remote work, Sentara Health employs associates in the following states: Alabama, Delaware, Florida, Georgia, Idaho, Indiana, Kansas, Louisiana, Maine, Maryland, Minnesota, Nebraska, Nevada, New Hampshire, North Carolina, North Dakota, Ohio, Oklahoma, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Washington, West Virginia, Wisconsin, and Wyoming.

• The Clinical Go-To: Act as the primary People Ops partner for Clinical Operations pods. You will attend various cross-functional meetings, listen to challenges, and translate those needs into efficient People Ops workflows • Operational Bridge: Serve as the functional operational lead for clinical-specific initiatives. You understand the clinical lifecycle and ensure the broader People Ops team has the context needed to execute flawlessly • Enablement & Solutions: Identify friction points in how clinical employees interact with our systems (onboarding, access, job changes) and jump in to provide the operational expertise required to solve complex issues • Operational Thought Partner: Serve as a key collaborator on clinical-specific people strategies, including the analysis and action planning for engagement surveys and the development of data-driven retention initiatives • Recruiting & Onboarding Alignment: Lead the synchronization between Clinical Recruiting, People Ops, and Clinical Ops, ensuring that high-volume hiring translates into a seamless day one and beyond experience • Partner with Employee Relations (ER) and Legal as the main People Operations Compliance lead, helping to build the People Ops compliance enablement roadmap for the entire U.S. population across the clinical and non-clinical space • Lead the maintenance and refresh of our Employee Handbooks to ensure that policies for both our clinical and non-clinical populations are accurate, compliant, and easy for employees to access and navigate • Manage the annual EEO-1 reporting process for the clinical and non-clinical population • Lead recurring audits of our People Operations processes to ensure we remain 100% audit-ready • Manage labor law poster refreshes and state-specific notices, ensuring they are accessible to all employees in the office and working remotely

• Line management of Clinical Operations staff • Manage staff by establishing goals that will increase knowledge and skill levels • Review workload for all staff in reporting chain • Provide expert operational oversight and guidance to support prioritization of activities • Assist in recruiting new staff • Ensure quality and adherence to Standard Operating Procedures • Work closely within appropriate business unit/region to ensure staff performance on studies • Develop and oversee training plans to address performance deficiencies • Organize and chair clinical staff meetings at regular intervals • Facilitate and support project and team/country reviews