Role Description The Client Director (Strategic Accounts) is the owner of Complexio's most important enterprise relationships post signature. Your primary mandate is customer success — accountable for value realisation, adoption, retention, and long-term partnership growth, with every renewal earned by outcomes already delivered. You also serve as the technical translator and feedback loop between the customer and Complexio's Product and Engineering teams, and when the situation requires it, you can run a full commercial cycle independently — but this is a supporting capability, not the centre of the role. You will shadow both Co-CEOs in strategic customer meetings and represent Complexio at C-suite level with full authority and credibility. - Senior owner of a portfolio of strategic enterprise accounts — multi-threaded relationships from day-to-day users through to C-suite, accountable for retention, health, and long-term partnership growth - Drive value realisation with the customer — co-define success metrics, drive adoption of the full Complexio platform (Event Knowledge Graph, Context Broker, Stevie, Enterprise Automator) against clear use cases, and maintain a customer-signed value narrative refreshed every QBR - Own account health and on-time renewals — track leading indicators, run structured recovery plans on at-risk accounts, and treat every renewal as earned by outcomes delivered - Own account revenue across renewal, upsell, and cross-sell — accountable for retained ARR and Net Revenue Retention; capable of running renewal and expansion cycles end to end, including procurement, legal, and contracting - Act as the technical translator between customer and Complexio Product/Engineering — hold credible architecture, integration, and security conversations with customer CTOs and IT teams without escalating every question, and convert operational requirements into structured Product input - Voice of the customer inside Complexio — feed prioritised, actionable feedback into Product Management on what works, what's friction, and what's missing - Lead executive engagement at C-suite level — represent Complexio independently, shadow Co-CEOs in strategic meetings, and orchestrate internal teams (Solution Engineering, Delivery, Product, Support) around shared account priorities Qualifications - 7+ years in a senior post-sale role — Customer Success, Account Management, Client Partner, or equivalent — managing strategic enterprise accounts in B2B SaaS or enterprise software, with a track record of driving Net Revenue Retention through documented value delivery - Executive presence and commercial capability — credible at C-suite level (alongside or in place of Co-CEO leadership), able to run renewal and expansion cycles independently including procurement and contracting - Technically fluent without being an engineer — able to translate between customer and Complexio Product/Engineering, hold credible architecture and security conversations, and convert operational requirements into structured Product input - Highly organised and proactive — disciplined enough to manage multiple high-complexity accounts simultaneously, calm under pressure, and energised by scale-up environments Requirements - Sector background in maritime, shipping, energy, or industrial - Experience with AI, data platforms, or knowledge graphs - Enterprise accounts in the $500k–$5M+ ACV range - Ability to step into a hunter role when situations have called for it Benefits - Senior individual contributor role with strategic influence over Complexio's most important customer relationships - Competitive base + performance component tied to retention, value realisation, and expansion outcomes - Direct access to the Co-CEO and senior leadership team - Opportunity to shape Complexio's customer success frameworks as the company scales

Role Description J.S. Held is seeking a senior seller-doer, either as an individual or a small established team, to join and help scale our Environmental, Health & Safety practice across the UK and the wider EMEA region. This is a rare opportunity to play a leading role in expanding a global professional services firm within one of Europe’s most mature and influential EH&S consulting markets. You will have the autonomy to shape UK strategy, the support of a global advisory platform, and the mandate to build and grow a high-impact EH&S practice. The successful candidate will combine strong commercial origination with hands-on technical leadership across EH&S disciplines, alongside trusted adviser credentials. You will be responsible for driving revenue growth, leading complex engagements, and expanding J.S. Held’s footprint in the UK. Job Responsibilities - Commercial Leadership & Business Development - Originate, develop and secure large, complex Health, Safety & Environment consulting engagements with multinational and upper mid-market clients across the UK and EMEA. - Build and maintain long-term relationships with C-suite and senior operational leaders. - Drive revenue growth, delivering ambitious individual and practice-level targets. - Collaborate closely with J.S. Held’s global practices to support cross-border and cross-disciplinary opportunities. - Represent J.S. Held externally at industry forums, conferences and client events across UK and European markets. - Client Delivery & Technical Leadership - Act as engagement lead and senior adviser on complex, high-risk and high-profile Health, Safety & Environment engagements across the UK. - Provide end-to-end HSE leadership and strategic guidance across the full HSE lifecycle, including: - Health & Safety - Development of H&S strategy and implementation of Occupational Health and Safety Management Systems, including policies, processes and tools. - H&S assurance and compliance activities, including audit experience and familiarity with UK H&S legislation and regulatory requirements, as well as statutory reporting obligations. - Site-based experience gained through industry or consulting, with familiarity in operational H&S risk assessments, site routines and practices at high-risk environments across industrial, construction, manufacturing, energy and utilities sectors. - Experience delivering safety culture and leadership programmes, with an understanding of human performance principles. - Experience in incident investigation, root cause analysis, and the development of corrective and preventative actions. - Environmental - Development and implementation of environmental strategy, including the design and deployment of Environmental Management Systems, along with supporting policies, processes, governance frameworks and tools. - Environmental assurance and compliance activities, including experience with permitting, regulatory compliance, liaison with UK regulators, and statutory environmental reporting requirements. - Operational environmental risk management, including waste management, pollution prevention, and control of environmental risks across industrial, manufacturing, energy, utilities and infrastructure sites. - Experience supporting environmental due diligence, liability assessments, and advisory work in relation to transactions, investments, divestments and disputes. - Delivery of ESG-related environmental risk, governance and performance improvement initiatives, including baseline assessments, gap analysis and programme development. Qualifications - Extensive experience in EH&S consulting within a professional services or advisory environment. - Demonstrated track record as a seller-doer, with consistent origination, development and successful conversion of new business opportunities. - Experience operating at Partner, Director or Principal level, with accountability for both revenue growth and client delivery. - Strong commercial acumen, with the ability to balance business growth, technical quality and delivery excellence. - Proven experience advising multinational clients and leading cross-border engagements. - Established credibility as an industry leader or subject matter expert, demonstrated through client relationships, professional affiliations, publications and speaking engagements. - Fluent in English, with the ability to operate confidently at executive, client and regulatory levels. Requirements - Compensation: J.S. Held offers a highly competitive base salary for this role. The level offered will vary depending on a range of factors, including (but not limited to) experience, skills, qualifications, location, and the scope of the role. - In addition to base salary, J.S. Held offers a highly rewarding annual bonus scheme. Equity participation is also available, subject to eligibility. Further details regarding these incentive plans will be discussed during the interview process. - Location: This role can be fully remote from anywhere within the UK. Frequent travel will be required. Benefits - We welcome applications from individuals with disabilities. If you require a reasonable adjustment in relation to any part of the recruitment process, please email [email protected], including “Applicant Adjustment” in the subject line, together with details of your request and contact information.

Director, Biostatistics Location: Remote, United States Director, Biostatistics Primary Work Location Remote - US Job Code2417 # of openings1 Job Description: Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Director, Biostatistics, to join our growing Biometrics team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The Director will serve as the lead statistician for assigned clinical development programs, leading the development and implementation of statistical solutions to support all phases of clinical trials, regulatory filing and facilitating decision-making. The Director will supervise study-level statisticians both in-house and at Contract Research Organizations (CROs), ensuring accountability for all biostatistics deliverables. What you will do: - Contribute to the development of clinical development plans and ensure that clinical development programs meet scientific, regulatory, and quality requirements. - Lead the biometrics team in all aspects associated with regulatory interactions/submission and develop strategies to address health authorities' inquiries pertaining to biometrics. - Provide scientifically rigorous statistical input and review for protocols, statistical analysis plans, interpretation of statistical results, and scientific publications. - Ensure delivery of high-quality, effective, and timely study- or program-level statistical deliverables for assigned projects. - Develop and/or implement innovative statistical approaches to enhance study design, analysis and data exploration methodologies. - Manage and/or mentor junior statisticians to foster their professional growth. - Promote effective collaborations with internal and external stakeholders. - Ensure compliance with relevant regulatory requirements and Agios standards across all study or program-level statistical activities. - Support establishment and maintenance of biometrics standards at Agios. - Serve as a comprehensive resource for clinical development and statistical matters. What you bring: - PhD in Biostatistics or related discipline with 7+ years biopharmaceutical industry experience - Experience in a program/lead statistician role (3+ years) - Experience with regulatory submissions - Experience representing biostatistics in interactions with health authorities - Fluent with statistical software including SAS, R, EAST, and nQuery - Excellent oral and written communication skills Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance of our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate with the above job description. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $183,000 and $275,000 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

• Define and execute the scientific vision and R&D roadmap aligned with company milestones • Lead the development of XtRNA Bio’s dual tRNA platform (elevation and suppression modalities) • Translate cutting-edge RNA biology into therapeutic strategies with clinical relevance • Oversee lead preclinical programs in focus indications (tRNA elevation in neuromuscular diseases, particularly CMT2D, and tRNA suppression in respiratory diseases, particularly CF) • Guide optimization of AAV-tRNA constructs, including vector design, capsid selection, and delivery strategies • Drive development of synthetic tRNA delivery systems to the respiratory tract • Supervise in vivo and in vitro studies, including rodent and NHP models, biomarker development, and functional endpoints • Drive IND-enabling studies, including biodistribution, toxicology, and dose-finding • Identify and characterize potential clinical applications of the XtRNA platform • Further develop and optimize our delivery modalities • Engage with relevant academic partners for PoC studies • Develop and nurture a dedicated Scientific Advisory Board • Partner with teams in CMC and vector manufacturing, regulatory and clinical strategy, intellectual property and business development • Align scientific execution with fundraising, partnerships, and corporate milestones • Establish a culture of scientific excellence, rigor, and innovation • Interface with external collaborators, KOLs, and Scientific Advisory Board members • Build, mentor, and inspire a high-performing multidisciplinary R&D team in the long term • Present scientific progress to investors, partners, and scientific conferences • Contribute to publications, patents, and company visibility