Agios Pharmaceuticals

Title: Patient Support Manager, Market Access (Florida) Location: United States Job Description: Patient Support Manager, Market Access (Florida) Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture - one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion - because our differences shape how we hire, collaborate, and innovate. Our team's proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific - it's deeply personal, grounded in the meaningful connections we have built. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Patient Support Manager (PSM) to join our growing Market Access team. We want someone who cares about this important work, and who's driven to connect to our mission of helping Sickle Cell patients. The Sickle Cell Patient Support Manager is responsible for coordinating comprehensive care for patients living with sickle cell disease. This role focuses on improving patient outcomes through education, care coordination, access support, and collaboration with healthcare providers and community resources. The Patient Support Manager serves as a key advocate for patients, ensuring timely access to treatment, adherence to care plans, and a high-quality patient experience. The Patient Support Manager will report to the regional Senior Manager Patient Access and Reimbursement Services. What you will do: - Contribute to the success of a best-in-class patient services program to support Agios' Commercial Vision Mission - Maintain long-term relationships with patients, caregivers, families, and HCPs to proactively identify and address new and ongoing barriers to access an ultra-rare drug - Fosters collaborative relationships with Agios field-based and home-office teams to ensure One Agios unified approach to supporting patient access and brand strategy - Exceed in delivering positive patient experience by assessing patient needs and develop action plans that identify and troubleshoot future access barriers to support treatment initiation and ensure continuation of the patient's treatment journey - Help patients make connections with other patients and serve as the "face of Agios" at patient meetings and industry conferences - Effectively shares reimbursement and other knowledge with customers and internal team members through collaboration and consultation for complex patient case studies - Maintains comprehensive understanding of the access process, navigation of health care systems, insurance plans, payer trends, and internal/external patient and financial assistance programs - Apply program business rules and work instructions to deliver uniform, consistent and sustainable service experience for patients - Maintain confidentiality of patient health information and act in compliance with all laws, regulations and Agios policies. - Demonstrates and maintains a high level of business acumen, understanding of Agios' business model, and the role of the patient support manager in commercializing the business and driving initiatives to meet company goals - Consistently leverages CRM reporting tools and data analytics to make strategic decisions about their territory and prioritize patient and customer needs - Is proficient in the use of Customer Relationship Management tool - Approaches patient and caregiver interactions with empathy, cultural humility, and an understanding of the lived experience and historical challenges faced by individuals with a rare disease - Applies a trauma‑informed approach to patient engagement, recognizing the impact of chronic pain, repeated healthcare interactions, and historical inequities on patient trust and decision‑making - Exceed in delivering a positive, dignified patient experience by building trust, actively listening, and addressing patient needs with compassion and urgency What you bring: - Bachelor's degree required. Health Care/Social Work/Nursing (or related field) a plus. - Minimum of five (5) years of experience directly related to patient service or market access (e.g., case management) in the healthcare or pharmaceutical/biotech industry. Ultra-rare disease experience a plus. - Knowledge of private payer, Medicare Part D and Medicaid structure, systems, and reimbursement process - Knowledge of benefit verification and prior authorization process for oral products - Experience and proficiency in working with a Customer Relationship Management System, such as Salesforce.com - Ability to proficiently use Microsoft Excel, Outlook, and Word - Ability to work independently and manage competing priorities - Experience working in cross-functional teams and effective in influencing without authority - Possess strong written and verbal communication skills, exceptional listening, critical thinking, and problem solving - This position may require ability to travel within the US up to 15% Preferred Qualifications - Rare, ultra rare, or genetic disease experience - Located in the Mid South region Concerned that you don't check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other's differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you're excited about this role but your previous experience doesn't align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee''s individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description.. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $110,029 and $165,044 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We're continuously looking to improve the inclusivity of our workforce. - Commitment to community. We're an active participant in the communities that surround us - the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Patient Advocacy Liaison Location: United States Job Description: Patient Advocacy Liaison (West) Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture - one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion - because our differences shape how we hire, collaborate, and innovate. Our team's proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific - it's deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Patient Advocacy Liaison to join our growing patient advocacy team. We want someone who cares about this important work, and who's driven to connect to our mission of helping these patient communities. The Patient Advocacy Liaison is a field-based position and will be responsible for responsible for catalyzing broader engagement with patients, caregivers, and patient advocacy organizations at a grassroots level. By building and managing these critical relationships, you will learn and gather deeper insights into the needs of the rare hemolytic anemia disease communities we serve. We are looking for a passionate and impact-focused person interested in joining an innovative patient advocacy team, who will partner with patients to bring about meaningful change. This position will report to the Senior Director of Patient Advocacy and focus on building Agios' profile in hemolytic anemias, such as thalassemia and sickle cell disease. The West territory will include Washington, Oregon, California, Nevada, New Mexico, Arizona and Colorado. What you will do: - Identify opportunities to build and strengthen relationships with local patients, patient support groups, advocacy organizations, and multicultural centers to ensure we better understand the needs of the patient communities. - Provide quarterly and annual business plans and contribute to developing the company's local community engagement plan. - Represent Agios at key patient-facing events to better understand the community's perspectives and needs, as well as to collect and share insights to enrich company strategy. - Identify disease education opportunities and collaborate with internal colleagues, including Agios Clinical Educators and Medical Affairs staff to deliver the right information in the most impactful manner. - Provide weekly updates to Patient Advocacy team members and cross-functional colleagues, ensuring a one-team mindset to support patients. - Serve as a liaison between the patient community and internal Agios teams, compliantly communicating key information from Agios programs to relevant stakeholders on a local level. - Share insights regarding on-the-ground issues, which will feed into Governmental Affairs programing and inform broader company objectives. - Adhere to Agios' policies and standard operating procedures and those regulatory and other ethical guidelines relevant to this role. - Embrace and demonstrate the Agios culture of absolute integrity, focused execution, incisive leadership, collaborative spirit and pursuit of excellence and innovation. - Meet/exceed agreed goals, delivering successful outcomes for both Agios and the patient communities we serve. What you bring: - Bachelor's degree in science, social science, or a related field. - Minimum of 3 years of patient advocacy experience, with 8+ years of progressive experience in a healthcare / biopharma setting. - Proven track record of working collaboratively and with flexibility in a fast-paced, multi-tasking environment, while maintaining operational quality. - Ability to think critically, strategically, and cross functionally. - Goal oriented, self-starter with a strong ability to self -manage. - Innovative mindset and a proven ability to challenge the status quo. - Ability to connect and build trusted relationships with patients, caregivers, and local advocacy organizations. - Strong understanding of the patient and caregiver experience in rare diseases. - Team-minded and able to react constructively in a high-energy and fast paced environment. - Excellent interpersonal skills, including oral and written communication skills and strong presentation skills. - Ability to build and sustain relationships with advocacy groups, government officials, and community leaders. - Ability to relate with a diverse group of individuals and develop rapport quickly. - Previous work with patients and advocacy groups in thalassemia, sickle cell disease or other rare diseases is preferred. - Proficient in basic computer skills and Microsoft Word systems. - Valid driver''''s license and clean driving record. - Ability and willingness to travel a minimum of 50% of the time. Concerned that you don't check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other's differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you're excited about this role but your previous experience doesn't align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Specific - Field/Remote: This is a remote based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We're continuously looking to improve the inclusivity of our workforce. - Commitment to community. We're an active participant in the communities that surround us - the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Title: Associate Director, Medical Review Lead, MSRM Job Description: Primary Work LocationRemote - US or Hybrid - Cambridge, MA Job Code2475 # of openings1 Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is seeking an Associate Director, Medical Review Lead to join the Medical Risk Management organization within Medical Safety & Risk Management (MSRM). This role provides oversight of medical review for Individual Case Safety Reports (ICSRs) across investigational and marketed products, ensuring medical accuracy, regulatory compliance, and high-quality safety data to support pharmacovigilance and risk management activities. Reporting to the Sr. Director, Head of Medical Risk Management, the Medical Review Lead serves as the primary point of contact for medical review and partners closely with Global Safety Leads, Pharmacovigilance Operations, and external vendors. This role bridges ICSR medical review and case processing with broader safety surveillance and risk management activities across the product lifecycle. The successful candidate will work cross-functionally and externally to ensure alignment with company policies, contractual obligations, and global regulatory requirements. This role requires strong medical and operational expertise in case processing and medical review, as well as the ability to effectively guide and oversee vendor performance in a dynamic and evolving environment. What you will do - Serve as the primary MSRM point of contact for ICSR medical review, partnering with Global Safety Leads, PV Operations, and vendors to ensure high-quality, compliant safety case assessment. - Provide medical oversight of ICSR review for investigational and marketed products, ensuring accuracy, consistency, and scientific rigor of medical assessments. - Review and approve key medical components of ICSRs, including narratives, coding, seriousness, expectedness, and company causality, based on source documentation. - Perform and oversee quality control (QC) of medical review activities, providing feedback and driving vendor accountability to quality and performance standards. - Ensure timely and compliant review of ICSR to ensure, including performing medical review activities directly when needed. - Partner cross-functionally to support safety surveillance, risk management activities, and development of clinical and regulatory documents. - Contribute to operational excellence through KPI/KQI monitoring, SOP development, training, and participation in system and process improvement. - Support inspection readiness by identifying quality issues, contributing to CAPAs, and representing MSRM for medical review and case management activities. What you bring: - MD/DO with a minimum of 3 years of relevant drug safety/pharmacovigilance Medical Review experience. - Minimum 1-2 years of vendor oversight in the biotechnology / pharmaceutical industry. - Expertise with MedDRA and WhoDD dictionary coding. - Expertise with software-based drug safety systems (ARGUS, ARISg, or equivalent) - Solid understanding of expedited safety reporting. - Solid knowledge of ICH and global regulations for clinical development and post-market activities pertaining to safety data collection, processing and reporting. - Excellent communication and interpersonal skills including the ability to interact effectively and collaboratively in cross-functional teams. - Excellent written and spoken English. - Strong computer skills (MS Office). - Ability to successfully prioritize and multi-task. Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $185,369 and $308,948 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Title: Senior Manager, Patient Access & Reimbursement Services, Market Access (East) Location: Eastern or Central time zones USA Job Description: Remote Job Code2433 # of openings1 Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Senior Manager, Patient Access and Reimbursement Services to join our growing Patient Access team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping Sickle Cell Disease patient communities. The Senior Manager, Patient Access and Reimbursement Services is a unique leadership opportunity, providing day-to-day oversight for two of our geographic regions (Northeast and Southeast). Each Senior Manager will lead a team of 6 Patient Support Managers (PSMs), who interact directly with Sickle Cell Disease patients, caregivers and healthcare professionals. This individual will lead all aspects of the regions day-to-day activities – accountable for performance coaching and development, case review and metrics, in the spirit of continuous improvement. The Senior Manager will report to the Director Patient Access and Reimbursement Services. What you will do: - Manage day-to-day patient access operations, including decision-making, and guidance on case escalations. - Collaborate with hub vendor, specialty pharmacies, and internal stakeholders to ensure seamless patient access. - Lead a team of PSM’s to deliver exceptional customer service for enrolled patients, caregivers, and healthcare professionals. - Coach and mentor direct reports through in depth coaching sessions, one-on-ones to ensure talent development and growth. - Collaborate with regional Sales leaders to ensure PSM responsibilities are clear within regional engagement and optimization plans and goals embodying the One Agios spirit. - Evaluate operational processes for efficiencies, providing recommendations to continually leverage technology and people for increased effectiveness and value. - Foster collaborative relationships with both internal and external partners with minimal guidance including but not limited to field sales, clinical nurse educators, national accounts, commercial operations/analytics and medical. - Partner with training and co-facilitate new hire and refresher training for new and existing PSMs. - Attend industry conferences and represent Agios, as needed. - Ensure compliance with all corporate and industry policies in collaboration with Agios Legal, Regulatory and Compliance. What you bring: - Bachelor’s Degree required. Health Care/Social Work (or related field) a plus. - Minimum 5 years + of work experience in healthcare/pharmaceuticals and 1 year of supervisory/management experience, or the equivalent combination of education and experience. - Experience and proficiency in working with a Customer Relationship Management System, such as Salesforce.com. - Demonstrated ability to motivate, coach, and inspire a team. - Desire to innovate and work in a fast-paced, flexible, and energetic environment. - Strong communication skills and interpersonal skills to guide others internally/externally. - Ability to communicate and execute company and commercial goals. - Possess strong written and verbal communication skills, exceptional listening, critical thinking, problem solving, negotiation and mediation skills. - Ability to navigate difficult conversations and handle sensitive issues with opposing opinions. - Highly passionate and enthusiastic about Agios core competencies. - This position may require ability to travel within United States up to 20%. Preferred Qualifications - Rare, ultra-rare, or genetically defined disease experience - Located in Eastern or Central time zones Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $131,035 and $196,553 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Title: Good Manufacturing Practice Job Description: Manager, GMP Quality Assurance - Clinical, QA Job Code 2484 # of openings 1 Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture - one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion - because our differences shape how we hire, collaborate, and innovate. Our team's proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific - it's deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Manager, GMP Quality Assurance - Clinical to join our growing QA team. We want someone who cares about this important work, and who's driven to connect to our mission of helping these patient communities. The Manager, GMP Quality Assurance, Clinical will be responsible for responsible for supporting and maintaining high quality levels on Agios Drug Substance and Drug Product by Contract Manufacturing Organizations (CMOs). This Quality Assurance professional must possess strong leadership skills in order to provide support to the QA Clinical team, and will assure the company, its affiliates and/or contractors associated with the manufacture testing, and release of products used for investigational clinical trials through Phase III/Validation comply with cGMPs and standards as well as regulations of applicable authorities. Reporting to the Associate Director, GMP Quality Assurance and being a member of the GMP clinical group. What you will do: - Conduct product release activities for drug substance and drug product for all phases of development including review and approval of master batch records and executed batch records. - Provide back-up support for clinical finished goods release on as-needed basis - Represent Agios QA on external CMOs project teams. Manage relationships with CMOs, which may include providing onsite oversight/monitoring of manufacturing campaigns as appropriate. - Coordinate QP release as appropriate. - Work collaboratively with key stakeholders on drug substance and drug product manufacturing strategies and plans to ensure investigational product releases within timelines. - Effectively interact with external contract manufacturers and testing laboratories as well as work as part of an internal multidisciplinary team to support manufacturing, testing, and product complaint investigations. - Assist in preparing or reviewing CMC sections of regulatory submissions. - Manage and address associated Investigations, CAPAs, Change Controls, Material Review Boards, OOS, etc. - Implement necessary Quality Agreements. - Conduct audits of CMOs, Testing Laboratories - Provide QA expertise in the development of Agios quality systems, processes, and procedures - Both domestic and international travel may be required (up to 10%) What you bring: - Bachelor's degree in biology, chemistry, life sciences or a related field - Minimum 6 years of Quality Assurance experience in a cGMP manufacturing environment. Experience related to oligonucleotide manufacture and/or process validation is a plus. - Strong knowledge of cGMP regulations, practices and trends pertaining to pharmaceutical product development, manufacturing, testing, and clinical operations - Experience working in virtual manufacturing and vendor management is a plus - Exercises judgment within broadly defined practices and policies in determining solutions and actions. - Demonstrates ability to identify and recognize critical decisions that will result in delays in schedule or operations that may jeopardize overall business activities. - Knowledge of drug substance, drug product solid dosage and fill/finish manufacturing principles, equipment, and processes. Concerned that you don't check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other's differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you're excited about this role but your previous experience doesn't align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee''''s individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description.. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexible. We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $110,029 and $165,044 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We're continuously looking to improve the inclusivity of our workforce. - Commitment to community. We're an active participant in the communities that surround us - the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Director, Regulatory Strategy (Pediatrics) Location: Remote United States Job Description: Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture - one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion - because our differences shape how we hire, collaborate, and innovate. Our team's proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific - it's deeply personal, grounded in the meaningful connections we have built. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Director, Regulatory Strategy to join our growing Regulatory Strategy team. We want someone who cares about this important work, and who's driven to connect to our mission of helping these patient communities. The Director, Regulatory Strategy will be responsible for developing regulatory strategies to support pediatric clinical development plans, working cross-functionally across the organization. This individual will lead cross-functional teams in preparing and overseeing development of compliant, high quality, nonclinical and clinical global regulatory submissions to support development, registration, or life cycle management activities. What you will do: - Develop and execute global regulatory pediatric strategy including the potential to accommodate expedited development needs - Provide global regulatory expertise in support of the development, review, and approval of cross-functionally developed strategies and documents intended to enable clinical trials and marketing authorizations for pediatric programs. - Plan, lead, develop, and review regulatory submissions, such as clinical trial applications, marketing applications, and life-cycle management submissions for pediatric programs. - Plan and lead health authority interactions, as needed, including the development and/or review of associated documents - Engage with Regulatory Authorities on project-related matters - Ensure adherence to current regulations associated with regulatory activities What you bring: - Bachelor's degree in life-sciences or related scientific discipline required; advanced degree (PhD, PharmD, or MS) preferred - 10+ years of experience in Regulatory Affairs within the biopharmaceutical industry - 7+ years of experience with pediatric plans (both in US and EU) - Experience leading preparations for health authority interactions and development of briefing documents - Strong knowledge of drug development, FDA, EMA and ICH guidelines and regulations - Excellent organizational and communication skills, both written and verbal - Ability to work independently as well as part of a team environment - Positive attitude, energetic and proactive - Proven ability to manage multiple projects, identify and resolve regulatory issues - Strong interpersonal skills and the ability to effectively work with others Concerned that you don't check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other's differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you're excited about this role but your previous experience doesn't align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee''s individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description.. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best. - Flexibility. We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $183,549 and $275,324 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We're continuously looking to improve the inclusivity of our workforce. - Commitment to community. We're an active participant in the communities that surround us - the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked

Title: Senior Manager, GCP & GVP, QA Location: United States Job Description: Senior Manager, GCP & GVP, QA Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture - one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion - because our differences shape how we hire, collaborate, and innovate. Our team's proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific - it's deeply personal, grounded in the meaningful connections we have built. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Sr. Manager, GCP & GVP Quality Assurance (QA) to join our growing GCP & GVP Quality team. We want someone who cares about this important work, and who's driven to connect to our mission of helping these patient communities. The Sr. Manager, GCP & GVP QA will be responsible for ensuring quality assurance and compliance of Agios Pharmacovigilance (PV) System and Agios sponsored interventional and non-interventional clinical trials in accordance with applicable Good Pharmacovigilance Practices (GVP) and Good Clinical Practice (GCP) regulatory requirements (e.g., FDA, ex-US, country specific), ICH GCP/GVP Guidelines, Agios Standard Operating Procedures (SOPs), and current industry standards and practices. They support, maintain and ensure effectiveness of quality programs and documentation to assure compliance with GVP and GCP and inspection readiness. What you will do: Responsible for collaborating cross-functionally to develop risk-based GCP/GVP internal and external audit program and annual audit plans. Conduct and/or oversee consultant auditors in the conduct of GCP/GVP audits of clinical trial internal and PV processes, GCP/GVP vendors, clinical investigator sites, clinical study documents and trial master files in accordance with annual audit plans. Provide timely GCP/GVP quality guidance and partner with key stakeholders to resolve compliance issues and support functions in the quality event management process, protocol deviations, risk management, issue escalation and CAPA development. Actively participate in the Clinical Trial Working Groups (CTWG) as the Quality Representative and serve as liaison to other GxP Quality teams as needed. Advise teams on controlled document development to ensure adherence to ICH and GCP/GVP guidelines and alignment with Agios Quality Policy and QMS. Support preparation, coordination and management of Health Authority inspections including Sponsor and Investigator Site Inspections. What you bring: Bachelor's degree in a scientific discipline preferred or Associate's degree with commensurate experience; advanced degree preferred Minimum 4-6+ years of progressive experience working within a clinical, regulatory or quality environment in the pharmaceutical or biotechnology industry Must have applied experience in quality assurance auditing and applicable regulations Prior experience in regulatory inspections preferred Ability to establish collaborative working relationships with internal and external stakeholders Self-motivated and able to effectively prioritize and manage multiple projects Excellent time and project management skills Effective written and verbal communication skills with the ability to communicate clearly and concisely Ability to take ownership of specific projects, and to effectively lead and work with team members on projects as required Ability to travel (~25%) domestically and internationally Concerned that you don't check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other's differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you're excited about this role but your previous experience doesn't align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employees individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description.. What we will give you: Deliberate Development. Your professional growth as one of our top priorities. Flexibility. We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best. Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. The current base salary range for this position is expected to be between $131,035 and $196,553 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We're continuously looking to improve the inclusivity of our workforce. Commitment to community. We're an active participant in the communities that surround us - the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Title: Associate Director, HEOR, Patient-Centered Research Location: Remote - US or Hybrid - Cambridge, MA Job Code2399 # of openings: 1 Job Description: Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture - one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion - because our differences shape how we hire, collaborate, and innovate. Our team's proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific - it's deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Associate Director, HEOR, Patient Centered Research to join our growing HEOR team who will lead Patient-Centered Research activities across all GDD programs, including but not limited to pyruvate kinase deficiency, thalassemia, and sickle cell disease. The HEOR team at Agios focuses on three pillars of activities: - Clinical development program support (e.g. patient-reported outcomes [PRO] strategies for clinical trials); - Real-world evidence generation (e.g. studies of natural history, burden of illness, treatment patterns, etc. using a variety of data sources including EMR, claims data, registries, chart reviews, and qualitative research); and, - Market access support (e.g. cost-effectiveness and budget impact modeling, AMCP and global value dossiers). We want someone who cares about this important work, and who's driven to connect to our mission of helping these patient communities. The Associate Director, HEOR will be largely focused on clinical development program support and PRO-related real-world evidence generation activities. They are expected to have expertise in clinical outcomes assessment (COA) strategy and analysis (including PROs) and strong qualitative research skills. They will be accountable for designing and conducting superior quality research that is medically relevant, scientifically valid, and aligned with the evidence generation and communication needs of our programs. This role will report to the Senior Director of Health Economics & Outcomes Research within Global Medical Affairs. What you will do: - Design and execution of quantitative and qualitative research (including PROs, preference studies, patient interviews, etc) to incorporate patient perspectives into clinical research and real-world evidence studies across the product lifecycle to support regulatory approval, product labeling, value demonstration, and market access activities; - Understanding patient insights and experiences with disease and treatment, through the measurement of outcomes that matter most to patients, including symptoms of disease, effects of treatment, and their impact on how patients feel and function; - Execution of gap analyses, patient interviews, and/or reviews of the literature and PRO labels, to select and/or develop appropriate patient-reported measures or other COAs for clinical trials in accordance with FDA and EMA guidance; - Collaboration with cross-functional partners on COA endpoint strategy; - Leading the preparation of the COA components of regulatory briefing books, clinical trial protocols, statistical analysis plans, clinical study reports, regulatory filing documents, and HTA submissions; - Collaboration with study statisticians on the analysis and interpretation of COA data, including assessments of clinically meaningful change; - Development and execution of publication plans (abstract, posters, and manuscripts) and preparation of internal and external-facing presentations of patient-centered research findings; - Ad hoc support of HEOR indication leads with real-word evidence generation activities such as natural history, burden of illness, treatment patterns, or other outcomes research studies; - Management of relationships and budgets with vendors to ensure timely completion of high quality projects; - Building strong relationships with internal partners and ensuring continuous and consistent communication regarding HEOR projects; - Compliance with all applicable laws, Agios policies, regulations and regulatory guidelines governing commercial and scientific interactions with healthcare professionals, payers, advocacy and other business partners. What you bring: - Master's or doctoral degree in health services research, sociology, psychology, psychometrics, public health, or related field; - At least 7 years of pharmaceutical/biotechnology industry, consulting, or academic experience, at least 5 years of which has been specifically focused on patient-centered research; - Demonstrated technical and strategic excellence in designing, conducting, and interpreting quantitative and qualitative patient-centered research; - Knowledge of the drug development process, PRO label claims, and regulatory guidance as it relates to patient-centered research, including the FDA's patient-focused drug development (PFDD) initiative; - Strong knowledge of the process for developing and validating outcome measures, methods for determination of clinically meaningful change thresholds, and clinical trial endpoint strategy; - Ability to lead multiple projects simultaneously across a variety of therapeutic areas; - Excellent written and oral communication skills; - Strong interpersonal skills and ability to collaborate on cross-functional teams; - Ability to interface with multiple external stakeholders, including patients, caregivers, clinicians, regulators, and payers; - Ability to navigate ambiguous, complex, and difficult situations; - Ability to travel approximately 10% of the time Concerned that you don't check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other's differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you're excited about this role but your previous experience doesn't align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employees individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. The current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We're continuously looking to improve the inclusivity of our workforce. - Commitment to community. We're an active participant in the communities that surround us - the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Title: Sr. Manager, Patient Advocacy & Engagement Location: Remote - US or Hybrid - Cambridge, MA Job Description: Sr. Manager, Patient Advocacy & Engagement Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture - one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion - because our differences shape how we hire, collaborate, and innovate. Our team's proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific - it's deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Sr. Manager, Patient Advocacy & Engagement to join our growing team. We want someone who cares about this important work, and who's driven to connect to our mission of helping these patient communities. The Sr. Manager, Patient Advocacy & Engagement role is ideal for someone motivated to work within a passionate, innovative function that partners closely with patients to drive meaningful change. The successful candidate will bring a strong blend of project management, strategic thinking and operational excellence. Reporting into and supporting the Associate Director, Strategy, Patient Advocacy & Engagement, this individual will play a key role in translating patient advocacy strategy into impactful materials and initiatives, ensuring consistent alignment between strategic objectives and execution. Success in this position requires excellent communication and organizational skills, with the ability to thrive in a fast-paced environment. The ideal candidate will be a creative problem solver who can think strategically as well as execute effectively, building strong relationships with external stakeholders and cross-functional internal teams. What you will do: - Support the translation of patient advocacy strategy into execution, ensuring initiatives, materials, and activities are aligned with overarching objectives and deliver meaningful patient impact. - Provide strategic, project management, and coordination support across key patient advocacy initiatives, working closely with Compliance and external vendors to ensure effective and compliant delivery. - Support the planning and execution of patient advisory boards, including agenda development, logistics, and stakeholder coordination. - Contribute to the development and management of patient-facing channels, including the Instagram and podcast initiatives, ensuring alignment with strategy and patient insights. - Partner with Corporate Communications to support integrated internal and external initiatives, including disease awareness campaigns, social media, and patient-focused engagement activities. - Support the delivery of patient advocacy activities at key conferences across PK deficiency, thalassemia, and sickle cell disease, including coordination of materials, approvals, and cross-functional inputs. - Maintain a strategic view of the patient advocacy congress landscape, identifying high-impact opportunities and coordinating appropriate internal representation. - Coordinate patient speaker engagements, ensuring alignment with broader objectives and supporting impactful integration of the patient voice across the organization. - Build and sustain strong relationships with external stakeholders, including patient organizations, advocacy groups, and vendors, contributing to long-term partnership value and collaboration. - Collaborate with operations to facilitate effective ways of working, including meeting coordination, action tracking, and innovative ways to incorporate AI into the work. What you bring: - Established project management and business operations skills - Minimum 5 years' work experience, including 3+ years in the pharmaceutical or biotechnology industry - Bachelor's degree or equivalent work experience - Prior experience in patient advocacy is desirable but not essential; enthusiasm and passion for making a difference are most important - Genuine interest in patient advocacy, with the ability to bring energy, sound judgement, and discretion to the role - Positive, adaptable, and empathetic working style, with the ability to act with urgency in a complex environment - Excellent communication, organizational, and prioritization skills, with the ability to manage competing deadlines and stakeholders - Strong attention to detail, with experience managing documentation, systems, and workflows (e.g. SharePoint, databases, or portals) - Strong problem-solving skills, with a proactive, solutions-oriented approach - Proven ability to work collaboratively across cross-functional teams and with external partners - Comfortable using approved AI tools to support organization, drafting, planning, and operational efficiency, in line with company policy and compliance requirements - Strong interpersonal skills, with the ability to build trusted relationships with internal and external stakeholders - Experience with Veeva and VisionTracker a plus Concerned that you don't check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other's differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you're excited about this role but your previous experience doesn't align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Agnostic: Work location for this role is based on employee''''s individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description.. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - We're all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you're at your best, we're at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $131,035 and $196,553 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We're continuously looking to improve the inclusivity of our workforce. - Commitment to community. We're an active participant in the communities that surround us - the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

AD, Field Access Management (Southeast) Primary Work Location Remote - US Job Code 2457 # of openings 1 Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic AD, Field Access Manager to join our growing team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The AD, Field Access Manager will be responsible for ensuring patients can access Agios therapies within the pharmacy benefit by navigating payer coverage and specialty pharmacy fulfillment pathways. The FAM is a regional expert in interpreting PBM/health plan policies and utilization management requirements (e.g., formulary status, PA criteria, step edits, quantity limits) and translating them into actionable guidance to remove access barriers in a compliant manner. This role involves investing time on-site with HCPs, assessing their access needs and facilitating collaboration with various stakeholders What you will do: - Serve as the regional subject-matter expert on payer/PBM coverage policies and access requirements for Agios products (formulary status, PA criteria, exceptions/appeals, step edits, distribution, and patient support pathways). - Educate stakeholders, HCPs, office staff, PA departments, on pharmacy benefit access processes and requested documentation to help reduce time to therapy. - Establish relationships with regional hematology centers as well as targeted community practices. - Partner with Patient Services on case escalations and barrier resolution, with clear handoffs and compliant documentation. - Collaborate with Specialty Pharmacy partners to support efficient triage/fulfillment and resolve access-related issues; share trends and improvement opportunities. - Coordinate with the National Accounts Payer Team to monitor and interpret PBM/health plan policy changes and utilization management criteria; share field insights and support consistent deployment of payer tools/resources. - Coordinate with Sales on account priorities and stakeholder engagement; provide compliant, non-promotional access information. - Identify access barriers and trends; share insights and support improvements to field tools, resources, and processes. - Document activities and outcomes in required systems; protect patient information and maintain data integrity. - Maintain current knowledge of relevant regulations, payer practices, and Agios policies, complete required training. Collaboration - Partner with Specialty Pharmacy, the National Accounts Payer Team, Patient Services, Sales, and Field Medical to align on stakeholder needs, share insights, and execute coordinated (non-promotional) access strategies. - Use established escalation pathways to resolve patient access barriers, clarify coverage requirements, and address operational issues impacting triage, fulfillment, and time to therapy. - Communicate payer/PBM policy changes, utilization management criteria, and access trends—and their field implications—to inform training, tools, and cross-functional action plans. Agios Values & Expected Behaviors - Aim High: Setting high standards and striving for excellence. - Come Together: Working collaboratively to achieve common goals. - Embrace Differences: Valuing diversity and inclusion in the workplace. - Bring Your Whole Self: Encouraging personal contributions and engagement. - Blaze New Trails: Taking bold steps and innovative approaches to problem-solving. These values foster a culture of collaboration, contribution, and high regard for others' perspectives, which is essential for their mission of developing innovative treatments for rare diseases What you bring: Requirements - - Bachelor’s degree or equivalent relevant experience. - Experience working in a field-based role with provider offices and/or with patient support HUB services - Working knowledge of pharmacy benefit access pathways including benefits investigation, prior authorization, exceptions, appeals, and PBM/health plan coverage decision-making. - Demonstrated ability to collaborate cross-functionally and influence without authority. - Strong communication, organization, and problem-solving skills; ability to manage multiple priorities across a territory. - Proficiency with CRM and case management/documentation tools (or similar systems). - Ability to travel within the assigned territory as required. Preferred Qualifications - Prior field access or managed care experience supporting specialty products. - Existing experience and/or relationships within the hematology space, including key regional hematology centers, i.e. Mount Sinai Center for Sickle Cell Disease (New York, NY), Aflac Cancer and Blood Disorders Center (Atlanta, GA), Duke University Health System, (Durham, NC), and Southwestern Health Resources (multiple locations, North Texas, TX). - Experience working directly with including providing next steps to provider offices, specialty pharmacies and hubs/patient support programs. - Relevant managed care experience with prior authorizations, appeals processes, and medical necessity for both established and new products entering the market. - Understanding distribution models and payer landscape for specialty therapies. - Experience partnering with National Accounts/Market Access and Sales teams in a matrix organization. Work Environment & Travel This is a field-based role with regular travel throughout the assigned region to engage targeted healthcare providers and care teams as appropriate to support access education and issue resolution, along with periodic internal meetings. Travel expectations and territory alignment will be defined based on business need. Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Specific – Field/Remote: This is a remote based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.