Role Description The Senior Director, Applied Insights leads the delivery of applied data science and machine learning solutions that generate actionable business insights generating measurable business impact across McGraw Hill’s business units. This role will use data to: - Segment users and customers to enable improved engagement - Implement data quality AI agents to improve data quality - Use sales history to perform churn analysis to better retain customers - Address other prioritized solutions Reporting to the VP of Data & Analytics, this role partners closely with Analytics Delivery Leads and business leaders to identify, prioritize, and solve high-impact, BU-specific problems using advanced analytics, statistical modeling, and machine learning. This role blends strategic consulting, hands-on data science leadership, and business-facing storytelling. The Sr. Director, Applied Insights must understand business strategy, sales, operations, & marketing while also guiding teams through model development, validation, and operationalization. Success requires deep collaboration across BU Leadership, Sales, Marketing, Data Science and AI, Data & Analytics, Global Technology Solution, and Customer Success to translate complex data into insights that drive adoption, efficacy, growth, and operational efficiency. This is a remote position open to applicants authorized to work for any employer within the United States. Qualifications - Bachelor’s degree in a quantitative or related field (e.g., Data Science, Statistics, Mathematics, Computer Science) or equivalent experience - Master’s degree or PhD preferred - 10+ years of progressive experience in data science, advanced analytics, or machine learning roles, including leadership experience - Proven experience delivering applied data science and machine learning solutions that improve business outcomes - Strong background in statistical modeling, predictive analytics, and machine learning techniques - Familiarity with modern data platforms, cloud-based analytics, and model operationalization - Experience translating ambiguous business problems into analytical frameworks and production-ready models - Ability to communicate complex analytical insights clearly to executive and non-technical audiences - Experience partnering cross-functionally with product, sales, marketing, and operations teams - Demonstrated people leadership experience building and managing high-performing technical teams - Close familiarity with data and data management practices, including an understanding of the challenges faced by a SaaS organization when dealing with data - Ability to understand the big picture and clearly articulate a holistic vision in a range of stakeholder contexts - Ability to influence leaders across the enterprise and build consensus Requirements - Experience developing customer segmentation, demand forecasting, or usage-based predictive models - Experience working with education data and understanding its unique challenges (e.g., efficacy, adoption, longitudinal analysis) - Experience and perspective on leveraging agentic AI to supplement existing data to increase intelligence Benefits - The pay range for this position is between $175,000 - $235,000 annually - Base pay offered may vary depending on job-related knowledge, skills, experience, and location - An annual bonus plan may be provided as part of the compensation package - A full range of medical and/or other benefits, depending on the position offered

• Own strategy and portfolio oversight for assigned energy infrastructure programs • Lead end-to-end execution of physical power infrastructure projects, from planning through commissioning • Serve as the primary decision-maker and escalation point for execution, technical, and delivery issues • Oversee and manage Project Managers and cross-functional coordination • Lead delivery of substation construction and utility interconnections • Coordinate with utilities, EPC firms, consultants, and internal stakeholders • Develop and manage integrated schedules, budgets, forecasts, and risk registers • Identify, track, and mitigate execution, constructability, and utility-related risks • Drive alignment across technical, commercial, regulatory, and schedule requirements • Provide clear, accurate reporting on project progress, risks, and milestones

Role Description This Associate Director of Clinical Consulting – Employer Segment will oversee clinical consulting client relationships, proactively identify clinical solutions, and manage clinical resource allocation for one or more of OptumRx's segments of Clinical Consulting support. They will work with clinical leadership in developing a strategy related to the delivery of proactive consultative services and driving clinical upsell targets, including deployment of appropriate use guidelines and protocols, utilization management strategies, clinical products/services, and formulary management strategies. The Associate Director of Clinical Consulting is expected to maintain strategic relationships with client leaders, key stakeholders, and brokers/consultants. They are accountable for direct management of a staff of clinical consultants and maintaining client satisfaction and retention. You’ll enjoy the flexibility to work remotely from anywhere within the U.S. as you take on some tough challenges. Primary Responsibilities: - Determine and manage clinical consulting resource allocation and assignment - Provide routine reporting to clinical leadership regarding milestone attainment and any significant issues within their segment that may be impacting overall team performance - Maintain understanding of individual client contracts and ensure proper execution of all clinical deliverables specific to those agreements - Ensure alignment of PBM clinical priorities with strategic goals and objectives of the overall organization and client - Collaborate with clients to establish achievable but aggressive clinical program goals, including: - Generic dispensing rate improvements - Implementation of utilization management programs - Improvement in medication adherence rates - Improvements in therapy gaps for key chronic disease states - Formulary compliance targets - HEDIS & NCQA measures - Formulate and deliver clinically-sound and fiscally responsible recommendations to clients based on trend - Provide mentoring/coaching for Clinical Consultants to enhance employee engagement, promote professional development, and maintain high levels of staff satisfaction - Assist in the recruitment, on-boarding, and mentoring of new Clinical Consultant team members - Provide superior clinical consultation and clinical account management with a focus on client satisfaction, client retention, and trend management - Comprehend and effectively explain formulary and clinical program changes to clients - Stay aware of and provide clinical market intelligence to clients - Provide education for clients, pharmacists, members, and physicians per contractual requirements - Communicate drug information to clients and respond to plan-specific clinical inquiries in a timely manner - Support other revenue-enhancement efforts (e.g., specialty, formulary, UM, mail, etc.) in coordination with client management/sales teams where appropriate - Routinely collaborate with client management leadership peers to provide well-coordinated, impactful quarterly performance review sessions with clients - Serve as a key resource for new clinical product/service ideation and liaison to clinical product development/management areas to create new or enhance existing programs - Identify and collaborate with account management on clinical renewal strategies - Drive enhanced client relationships through senior-level strategic discussions and planning which addresses issues of highest priority for the client - Consistently look at existing processes, methods, and materials to find opportunities for improvement - Maintain strategic relationships with client leaders, key stakeholders, and brokers/consultants - Support sales and marketing including participating in RFP/finalist activities as needed based on current standard operating procedure - Serve as Subject Matter Expert (SME) for other departments on Clinical Consulting-specific issues/inquiries - Actively participate in, and in some cases lead, departmental and interdepartmental workgroup and project work Qualifications - Bachelor of Science in Pharmacy or Doctor of Pharmacy degree - Active, unrestricted US state-specific pharmacist license - 5+ years of pharmacy practice experience or equivalent - 3+ years of client-facing or clinical account management experience with 2+ years of providing formal client presentation - 2+ years of leadership experience or equivalent clinician lead - Experience communicating professionally to internal stakeholders and external clients - Experience managing multiple clients simultaneously - Basic competency in Microsoft Word, Excel, PowerPoint, Teams, and Outlook - Solid clinical and analytic background - Ability and willingness to travel up to 25% Preferred Qualifications - MBA or similar advanced degree - Managed Care and/or PBM experience - Formalized sales skills training - Formalized leadership skills training - Formalized presentation skills training Benefits - Comprehensive benefits package - Incentive and recognition programs - Equity stock purchase - 401k contribution (all benefits are subject to eligibility requirements) Application Deadline This will be posted for a minimum of 2 business days or until a sufficient candidate pool has been collected. Job posting may come down early due to volume of applicants.

Role Description This Real World Evidence (RWE)/Health Economics (HEOR) Contractor role supports the RWE/HEOR Senior Director in leading RWE execution for pipeline assets. The role is fun and flexible with a mix of both study execution and data analytics. This person will be accountable for developing and delivering components of the evidence generation plan (including RWE and economic value evidence), and driving high-quality deliverables that inform internal decision-making during product development, pre-launch readiness, and lifecycle planning. The role is anchored to 1–2 priority pipeline assets/indications. This is a remote role based with flexible hours. We are currently seeking an individual with 20-30 hours of weekly availability with potential to increase hours in late 2026/2027. Responsibilities - Evidence strategy and planning: Maintain US RWE & HEOR plans for 1–2 priority pipeline assets/indications, aligned to US medical, payer, and access needs; translate strategy into actionable workplans, timelines, and resourcing proposals. - Study leadership (RWE/HEOR): Own day-to-day leadership for assigned real-world evidence and health outcomes studies (e.g., real-world evidence studies, cost-effectiveness/budget impact analyses, burden of illness, treatment patterns, patient-focused outcomes) including design and execution in partnership with internal functions and external vendors. - Scientific communication and quality: Draft/review project specifications, protocols, statistical analysis plans, study reports, abstracts, posters, and manuscripts; ensure adherence to SOPs and high scientific/operational quality. - Analytic execution and statistics: Execute ad hoc analyses in clinical trial, claims and PCOR data as needed for ad hoc and protocol/SAP driven analyses. This may include feasibility or full protocol execution. - Governance, compliance, and capability building: Complete required training, adhere to company/department SOPs, and contribute to continuous improvement of processes that enable efficient planning, execution, and dissemination of RWE & HEOR deliverables. Qualifications - Master’s degree or PhD in epidemiology, health economics and outcomes research, public health, biostatistics, or related discipline. - At least 1+ years of experience in the pharmaceutical industry and/or managed care, hospital, academic, or healthcare consulting environment with exposure to HEOR/RWE strategy and application. - Proficiency with SAS and/or R for statistical programming. Preference for experience in clinical trials OR claims data. - Expertise in RWE and study designs/methods evidenced by publications and/or contributing to study concept sheets and protocols, reviewing/authoring key sections of statistical analysis plans and study reports, and ensuring publication/disclosure readiness in accordance with ICJME criteria. - Strong communication and presentation skills, demonstrated by developing and presenting clear, decision-oriented materials (e.g., evidence strategy slides, executive readouts) and summarizing outcomes/next steps for senior audiences. Preferred Qualifications - Demonstrated success developing and executing health outcomes research plans and delivering high-quality data generation outputs. - Experience managing real-world data sources and vendors (e.g., claims, EHR, registries) and translating findings into actionable insights and value messages. - Demonstrated ability to influence without authority in a matrix environment, evidenced by aligning cross-functional stakeholders on objectives/trade-offs, documenting decisions, and driving actions to closure. - Experience in PCOR implementation and validation. Work Location and Condition At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan, and Tennessee. You must have access to work in a setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communicate via video conference, etc.) at your remote location. Compensation The hourly pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity. - Contractor Hourly Compensation Range: $55 — $90 USD Company Description Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – create a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.