Role Description This Associate Director of Clinical Consulting – Employer Segment will oversee clinical consulting client relationships, proactively identify clinical solutions, and manage clinical resource allocation for one or more of OptumRx's segments of Clinical Consulting support. They will work with clinical leadership in developing a strategy related to the delivery of proactive consultative services and driving clinical upsell targets, including deployment of appropriate use guidelines and protocols, utilization management strategies, clinical products/services, and formulary management strategies. The Associate Director of Clinical Consulting is expected to maintain strategic relationships with client leaders, key stakeholders, and brokers/consultants. They are accountable for direct management of a staff of clinical consultants and maintaining client satisfaction and retention. You’ll enjoy the flexibility to work remotely from anywhere within the U.S. as you take on some tough challenges. Primary Responsibilities: - Determine and manage clinical consulting resource allocation and assignment - Provide routine reporting to clinical leadership regarding milestone attainment and any significant issues within their segment that may be impacting overall team performance - Maintain understanding of individual client contracts and ensure proper execution of all clinical deliverables specific to those agreements - Ensure alignment of PBM clinical priorities with strategic goals and objectives of the overall organization and client - Collaborate with clients to establish achievable but aggressive clinical program goals, including: - Generic dispensing rate improvements - Implementation of utilization management programs - Improvement in medication adherence rates - Improvements in therapy gaps for key chronic disease states - Formulary compliance targets - HEDIS & NCQA measures - Formulate and deliver clinically-sound and fiscally responsible recommendations to clients based on trend - Provide mentoring/coaching for Clinical Consultants to enhance employee engagement, promote professional development, and maintain high levels of staff satisfaction - Assist in the recruitment, on-boarding, and mentoring of new Clinical Consultant team members - Provide superior clinical consultation and clinical account management with a focus on client satisfaction, client retention, and trend management - Comprehend and effectively explain formulary and clinical program changes to clients - Stay aware of and provide clinical market intelligence to clients - Provide education for clients, pharmacists, members, and physicians per contractual requirements - Communicate drug information to clients and respond to plan-specific clinical inquiries in a timely manner - Support other revenue-enhancement efforts (e.g., specialty, formulary, UM, mail, etc.) in coordination with client management/sales teams where appropriate - Routinely collaborate with client management leadership peers to provide well-coordinated, impactful quarterly performance review sessions with clients - Serve as a key resource for new clinical product/service ideation and liaison to clinical product development/management areas to create new or enhance existing programs - Identify and collaborate with account management on clinical renewal strategies - Drive enhanced client relationships through senior-level strategic discussions and planning which addresses issues of highest priority for the client - Consistently look at existing processes, methods, and materials to find opportunities for improvement - Maintain strategic relationships with client leaders, key stakeholders, and brokers/consultants - Support sales and marketing including participating in RFP/finalist activities as needed based on current standard operating procedure - Serve as Subject Matter Expert (SME) for other departments on Clinical Consulting-specific issues/inquiries - Actively participate in, and in some cases lead, departmental and interdepartmental workgroup and project work Qualifications - Bachelor of Science in Pharmacy or Doctor of Pharmacy degree - Active, unrestricted US state-specific pharmacist license - 5+ years of pharmacy practice experience or equivalent - 3+ years of client-facing or clinical account management experience with 2+ years of providing formal client presentation - 2+ years of leadership experience or equivalent clinician lead - Experience communicating professionally to internal stakeholders and external clients - Experience managing multiple clients simultaneously - Basic competency in Microsoft Word, Excel, PowerPoint, Teams, and Outlook - Solid clinical and analytic background - Ability and willingness to travel up to 25% Preferred Qualifications - MBA or similar advanced degree - Managed Care and/or PBM experience - Formalized sales skills training - Formalized leadership skills training - Formalized presentation skills training Benefits - Comprehensive benefits package - Incentive and recognition programs - Equity stock purchase - 401k contribution (all benefits are subject to eligibility requirements) Application Deadline This will be posted for a minimum of 2 business days or until a sufficient candidate pool has been collected. Job posting may come down early due to volume of applicants.

Role Description This Real World Evidence (RWE)/Health Economics (HEOR) Contractor role supports the RWE/HEOR Senior Director in leading RWE execution for pipeline assets. The role is fun and flexible with a mix of both study execution and data analytics. This person will be accountable for developing and delivering components of the evidence generation plan (including RWE and economic value evidence), and driving high-quality deliverables that inform internal decision-making during product development, pre-launch readiness, and lifecycle planning. The role is anchored to 1–2 priority pipeline assets/indications. This is a remote role based with flexible hours. We are currently seeking an individual with 20-30 hours of weekly availability with potential to increase hours in late 2026/2027. Responsibilities - Evidence strategy and planning: Maintain US RWE & HEOR plans for 1–2 priority pipeline assets/indications, aligned to US medical, payer, and access needs; translate strategy into actionable workplans, timelines, and resourcing proposals. - Study leadership (RWE/HEOR): Own day-to-day leadership for assigned real-world evidence and health outcomes studies (e.g., real-world evidence studies, cost-effectiveness/budget impact analyses, burden of illness, treatment patterns, patient-focused outcomes) including design and execution in partnership with internal functions and external vendors. - Scientific communication and quality: Draft/review project specifications, protocols, statistical analysis plans, study reports, abstracts, posters, and manuscripts; ensure adherence to SOPs and high scientific/operational quality. - Analytic execution and statistics: Execute ad hoc analyses in clinical trial, claims and PCOR data as needed for ad hoc and protocol/SAP driven analyses. This may include feasibility or full protocol execution. - Governance, compliance, and capability building: Complete required training, adhere to company/department SOPs, and contribute to continuous improvement of processes that enable efficient planning, execution, and dissemination of RWE & HEOR deliverables. Qualifications - Master’s degree or PhD in epidemiology, health economics and outcomes research, public health, biostatistics, or related discipline. - At least 1+ years of experience in the pharmaceutical industry and/or managed care, hospital, academic, or healthcare consulting environment with exposure to HEOR/RWE strategy and application. - Proficiency with SAS and/or R for statistical programming. Preference for experience in clinical trials OR claims data. - Expertise in RWE and study designs/methods evidenced by publications and/or contributing to study concept sheets and protocols, reviewing/authoring key sections of statistical analysis plans and study reports, and ensuring publication/disclosure readiness in accordance with ICJME criteria. - Strong communication and presentation skills, demonstrated by developing and presenting clear, decision-oriented materials (e.g., evidence strategy slides, executive readouts) and summarizing outcomes/next steps for senior audiences. Preferred Qualifications - Demonstrated success developing and executing health outcomes research plans and delivering high-quality data generation outputs. - Experience managing real-world data sources and vendors (e.g., claims, EHR, registries) and translating findings into actionable insights and value messages. - Demonstrated ability to influence without authority in a matrix environment, evidenced by aligning cross-functional stakeholders on objectives/trade-offs, documenting decisions, and driving actions to closure. - Experience in PCOR implementation and validation. Work Location and Condition At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan, and Tennessee. You must have access to work in a setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communicate via video conference, etc.) at your remote location. Compensation The hourly pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity. - Contractor Hourly Compensation Range: $55 — $90 USD Company Description Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – create a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

• Providing technical and commercial support for the sales force, including traveling with Sales Territory Managers and Sales Representatives to power users, and engineering firms who specify in the C&I market • Assisting in the generation of targeted proposals and present proposals, as agreed between Sales Representatives or Territory Managers, in the C&I market • Providing first-level follow-up on leads generated by marketing programs and follow-up support for each account in the C&I market • Supporting or initiating contact with C&I end users, specifiers and contractors as agreed between the Regional Vice President and local Sales Territory Managers and representatives • Supporting promotional activities focused on the C&I market such as Expos, Lunch and Learns, IEEE presentations, and similar activities with customers and technical consultants/specifiers • Working with the Sales Representatives and Territory Managers to drive S&C product specifications in the C&I market • Providing regular feedback to S&C Marketing regarding proposals, accounts, and competitive situations within the C&I market • Providing first-level technical assistance to Power Systems Solutions concerning C&I applications and customer requirements during installation and commissioning of C&I projects • Tracking all C&I RFI’s and RFQ’s in the assigned area of responsibility • Engage in start-up, training, and support associated with company’s equipment • Assisting with strategizing, follow-up and closing an order, if required by the Sales Territory Managers

Role Description This NON-PAID philanthropic board member would be our Board Treasurer. This position is purely philanthropic and is for an executive who wants to give back and likely has experienced the cancer journey with a friend or loved one. Nonprofit board members give of their time, talent, and treasure. We have a "working board," meaning our board members are involved in our operations, donating an average of 5 hours per week. We do have a donation requirement because our funders (including grant foundations) require that our board be donors to the organization before they will provide grants. - Understand and be experienced in financial accounting. Experience in nonprofit organizations is a plus. - Serve as the financial officer of the organization. - Help develop a finance committee and serve as Chair of the finance committee. - Manage, with the finance committee, the board’s review of and action related to organization finances. - Work with the chief executive to ensure that appropriate financial reports are made available to the board on a timely basis. - Assist the chief executive in preparing the annual budget and presenting the budget to the board for approval. - Work with CEO to develop project budgets for grant applications. - Ensure development and board review of financial policies and procedures. Board members must be local to the Los Angeles metro. We are actually located in Monrovia, San Gabriel Valley. Most work will be remote, as will be board meetings, which are conducted online. Qualifications - Experience in QuickBooks Bookkeeping, Budgeting, Projections, Finance, Reporting, 990 preparations, and Board Financial Reports. - 5-10 years of job experience (not experience as a board member). Requirements - Board of Directors. - Finance. - Non-Profit Management. Benefits - Supporting Cancer Families in the Home. - Helping Those in Need. - Giving Back. - Improving our community. - Be Blessed by Blessing Others. - Flexible schedule. - Flexible work from home options available. Company Description Here to Serve (www.HereToServe.org), a 501 (c) (3) charity, provides coordinated non-medical support programs and resources for the parent(s) with children battling cancer from the point of diagnosis throughout treatment. 60% of the cancer journey happens in the home without coordinated support. Here to Serve fills this healthcare gap. We believe a child or young parent’s cancer diagnosis is a life-altering “journey.” For that reason, the care and support of families is required to prevent caregivers from losing their health, home, and job, and entering into bankruptcy. Therefore, we provide non-medical wraparound services to meet the daily living needs of families and caregivers navigating their child’s cancer. Cancer is a three-legged stool, not two! Research, Treatment, AND Journey! The journey is as profound and consequential as cancer research and hospitals that treat cancer. Therefore, a family's cancer "journey" requires the same awareness, support, and funding as cancer research and hospitals that treat cancer. Of the billions of dollars of funding for cancer, only .001% is provided to families with children actually battling cancer!