• Leverage a broad range of techniques to turn data into actionable business insights • Tackle complex analytical problems and uncover trends • Operate in a fast-paced environment managing projects end-to-end • Work with stakeholders to identify opportunities for leveraging company data • Mine and analyze data to drive optimization and improvement • Develop custom data models and algorithms • Communicate business requirements to ensure buy-in from all departments • Participate in projects to provide data and analyses as needed

Role Description We have an exciting opening for an experienced DMPK scientist. The incumbent will contribute as a DMPK scientist on project teams from drug discovery through all stages of drug development, with a scientific background on key aspects of DMPK science, including but not limited to: - In vitro and in vivo ADME - Animal PK - Toxicokinetics - Drug metabolism - DME- and transporter-based DDI - 14C-ADME studies - QWBA - Human PK prediction This position reports to the Head of Nonclinical Sciences and may be based at our headquarter location in New Haven, CT or a remote role based within the U.S. Principal Responsibilities - Serve as a project DMPK scientist and advise discovery teams on strategies for early ADMET profiling up to the selection of lead candidate into preclinical development. - Represent DMPK function on company-wide development teams to support the advancement of preclinical and clinical development assets. - Contribute to the in vitro DDI and other in vitro/in vivo DMPK assessment for individual preclinical drug candidates and ensure timely availability of key data as part of the IND enabling activities. - Recommend stage appropriate clinical DDI strategy to the clinical pharmacology function. - Contribute to outsource of DMPK studies and ensure timely and high quality conduct of in vitro and in vivo ADMET studies. - Partner with key CROs to develop and customize ADMET assays to support PROTAC drug discovery and development. - Contribute to the preparation of DMPK component of regulatory documents such as IND, IB, or other documents. - Stay up to date with the scientific advance and regulatory landscape for DMPK science in drug discovery and development. Qualifications - In-depth knowledge or expertise on one or several aspects of DMPK science in drug discovery and/or development, such as biotransformation, bioanalysis, pharmacokinetics, toxicokinetics, DME- and transporter-based drug-drug interaction, PBPK or PK/PD modeling, human PK prediction. - General knowledge of drug discovery and development process. - Experience in representing DMPK function on discovery and development teams. - Ability to integrate DMPK knowledge of individual drugs and prepare DMPK components of regulatory documents. - Hands-on experience and proficiency in PK analysis with PK or modeling software such as Phoenix. - Knowledge of relevant regulatory guidance in areas such as drug-drug interaction, bioanalysis, and GLP. Requirements - Ph.D. in pharmaceutical science, chemistry, biochemistry, or related scientific discipline with ten-plus years of relevant experience in DMPK in the biopharmaceutical industry or CROs supporting pharmaceutical development, preferably with a focus on small molecules. - Direct experience with PROTAC, molecular glue, or ADC highly desirable. - Arvinas will not be providing VISA sponsorship for this position. You must have the ability to work without a need for a current or future VISA sponsorship. - The duties of this role are generally conducted in a combination of lab and home office environments. - Employees must be able, with or without an accommodation to lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving, analysis and dialogue; collaborate with others; maintain general availability during standard business hours. Benefits - Competitive package of base and incentive compensation. - Comprehensive benefits program designed to support the health, wellness and financial security of employees and their families. - Group medical, vision and dental coverage. - Group and supplemental life insurance. - And much more. Company Description Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. For more information about Arvinas, please visit www.arvinas.com and connect on LinkedIn and X .

• Work with large and complex data sets to solve a wide array of challenging problems using different analytical and statistical approaches • Apply technical expertise with quantitative analysis, experimentation, data mining, forecasting, and the presentation of data to identify trends and patterns that can inform decision-making • Collaborate closely with Product, Engineering, Finance, Data Science, Advanced Analytics, Data Engineering, and other cross-functional teams to provide actionable insights • Design and build metrics and dimensions to monitor product and business performance • Build sophisticated reporting and analytical tools that empower stakeholders to make data-driven decisions • Present findings and recommendations to stakeholders, including senior leadership, in a clear and concise manner • Leverage AI to automate repetitive tasks and empower stakeholders

• Support the development of analytical capability to quantify the marginal cost of every session incurred on Electrify America’s network • Support framework development to account for related wholesale energy market parameters • Support the implementation of predictive analytics for marginal utility cost • Quantity financial savings on an ongoing basis for Electrify America, Electrify Canada, and Commercial Customers