The University of Minnesota has five campuses throughout the State of Minnesota and offers its student body nineteen colleges and schools with a variety of undergraduate, graduate,
Bioinformatics Research Scientist - Data Manager
Location
Minnesota
Posted
25 days ago
Salary
$90.9K - $110K / year
Seniority
Lead
Job Description
Bioinformatics Research Scientist - Data Manager
University of Minnesota
Bioinformatics Research Scientist - Data Manager Location: Minneapolis United States Full/Part Time Full-Time Regular/Temporary Regular Job Description: About the Job The Bioinformatics Research Scientist/Data Manager will a lead major initiative for the development and implementation of a centralized Data Management Core to support the expanding longitudinal clinical research cohort and associated collaborative studies at the Grossman Center for Memory Research and Care. This role will establish and lead the infrastructure necessary for secure data inventory, integration, processing, governance, and advanced analytics to support bioinformatics, translational, and clinical research initiatives. The role will have high impact that will enhance data integrity and reproducibility, accelerate bioinformatics discovery, improve competitiveness for NIH center-level funding, enable integration across clinical, imaging, and biomarker platforms, and position the Grossman Center as a data-driven leader in memory research and care. Work Schedule: Remote, Monday - Friday, 9am - 5pm 60% - Bioinformatics and Biostatistical Data Management: - Independently design and implement a centralized data repository architecture for clinical, imaging, genomic, biomarker, and survey data. - Lead and develop a comprehensive Data Management Core strategic plan. - Lead the development and management of a secure data storage solutions compliant with institutional, HIPAA, and IRB standards. - Lead the development of structured data pipelines for ingestion, transformation, harmonization, and validation. - Independently develop a standardized metadata frameworks and data dictionaries. - Manage the development of a centralized data inventory catalog. - Independently develop standard operating procedures (SOPs) for data access, sharing, and governance. - Manage and implement version control and documentation practices to ensure reproducibility. - Collaborate with institutional IT and compliance offices to ensure regulatory adherence. - Work closely with clinical research coordinators, biostatisticians, and collaborating institutions. 25% - Bioinformatics and biostatistical analysis of multi-Omics datasets: - Lead the development and implementation of standardized data ingestion and QC pipelines for the longitudinal cohort study. This includes the automated workflows for preprocessing and quality control of: - Longitudinal clinical data - Neuroimaging data - Biospecimen-linked datasets - Genomic and multi-omics data - Provide subject matter expertise on statistical modeling, machine learning, and data mining projects. - Facilitate integration of cohort data with external collaborative datasets. - Provide analytic consultation for investigators developing grants and manuscripts. - Work closely with clinical research coordinators, biostatisticians, and collaborating institutions. - Harmonize multi-site datasets to ensure consistency and interoperability. - Provide subject matter expertise on data sharing initiatives and preparation of datasets for grant submissions and publications. 10% - Training others in the lab and center for utilizing biocomputational pipelines: - Independently provide data mining tutorial pipeline establishment for trainees to learn and use. - Lead routine bimonthly workshops for trainees to learn data processing and analysis. - Lead biweekly meetings to monitor trainees' progress. - Lead the development and implementation of a documented data governance and SOP framework. 5% - Manuscript preparation and submission: - Generate analytic reports, dashboards, and visualizations to support leadership decision- making. - Contribute to NIH and foundation grant proposals, including sections on data management and analytic plans. - Support preparation of manuscripts and conference presentations. - Independently create integrated analytic dataset supporting a bioinformatics project or grant application. Qualifications Required Qualifications: - An Advanced Degree with substantial research and publication record. - Extensive bioinformatics and biostatistical experience including NGS data analysis, including RNA-seq, scRNA-seq, Spatial Transcriptomics (10xVisium, Nanostring GeoMx), ChIP-seq, ATAC-seq, Cut&Run/Tag, scATAC-seq, Infinium MethylationEPIC Array, WGBS, MS/MS, CyTOF, Hi-C, WGS/WES dataset, Proteomics, Lipidomics/Metabolomics; Strong background in R and Python programming, and statistical analysis. - Data management responsibilities including building center data storage platform, data process, format and standardization, data upload, data warehouse maintenance and distribution. - Bioinformatics training: data mining tutorial pipelines, and routine workshops for trainees to learn data processing and analysis. Preferred Qualifications: - Knowledgeable about wet lab experiments; Linux and cluster computing environment; multi-project management. Pay and Benefits Pay Range: $90,930.38 annually - $110,000 annually; depending on education/qualifications/experience. Time Appointment: 100% Appointment Position Type: Faculty and P&A Staff Please visit the Office of Human Resources website for more information regarding benefit eligibility. The University offers a comprehensive benefits package that includes: - Competitive wages, paid holidays, and generous time off - Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program - Low-cost medical, dental, and pharmacy plans - Healthcare and dependent care flexible spending accounts - University HSA contributions - Disability and employer-paid life insurance - Employee wellbeing program - Excellent retirement plans with employer contribution - Public Service Loan Forgiveness (PSLF) opportunity - Financial counseling services - Employee Assistance Program with eight sessions of counseling at no cost - Employee Transit Pass with free or reduced rates in the Twin Cities metro area Employment Requirements Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment. About the U of M The University of Minnesota, Twin Cities (UMTC) The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.
Related Guides
Related Categories
Related Job Pages
More Research Scientist Jobs
Senior Scientist I Analytical Development
Alumis Inc.Founded in 2021, Alumis Inc. is committed to revolutionizing the lives of people with immune-mediated diseases. The company’s culture emphasizes collaboration
Title: Senior Scientist I Analytical Development Location: South San Francisco United States Job Description: Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. The small molecule CMC team is seeking highly motivated Sr. Scientist I of Analytical Development to help build our dynamic small molecule CMC group at Alumis. The successful candidate will help to support the analytical development and quality control activities from the preclinical phase through late-stage clinical development. Having analytical development expertise and experience in working with CMOs/CTLs, coupled with thorough understanding of the associated quality and regulatory awareness are key assets. RESPONSIBILITIES - Support development, validation, and transfer of analytical methods to support starting material, intermediate, drug substance and drug product testing at CMOs/CTLs - Execute and/or support the in-house method development activities using UPLC/HPLC, LC-MS, KF, and dissolution instrumentation and techniques for Phase 1 to late-stage drug development - Review CMO/CTL analytical data (in-process, release, and stability data), protocols and reports - Trend stability and release data using statistical methods - Assist in investigation for various non-conformance events at CMOs/CTLs - Collaborate with CMC team, QA and CMOs/CTLs towards timely generation and approval of documents - Communicate scientific results (oral and written) in a clear and concise manner within cross-functional teams - Author technical reports and documents in support of regulatory filing - Assist in preparation of CMC documents for regulatory submissions (IND, IMPD, and/or NDA) THE IDEAL CANDIDATE - BS/MS in chemistry or pharmaceutical sciences with 5+ years of experience in analytical development - Experience with analytical techniques for small drug molecules and oral solid formulations required, including UPLC/HPLC, LC-MS, KF, dissolution testing, IR, particle size analysis, and solid-state characterization techniques - Proven track record in applying analytical techniques to solve challenging problems - Experience in working with CMOs and CTLs - Experience in early to late-stage drug development - Strong organizational and communication skills - Comfortable in a fast-paced small company environment and a strong team player - Experience and knowledge in ICH, cGMP and regulatory requirements This position is located in South San Francisco, CA. At this time, we are not considering fully remote applicants. The salary range for this position is $112,000 USD to $135,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company's compensation practices. Alumis Inc. is an equal opportunity employer. Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program. Other benefits include: - Health insurance premiums paid at 90% for employee, 80% for dependents - Free access to Genentech Bus & Ferry Share program - $100 monthly cell phone stipend - Unlimited PTO for Exempt employees - Free onsite gym and a kitchen stocked with yummy snacks and drinks! We are a hard-working, collaborative team on a mission to transform patient's lives-- and we aspire to elevate, challenge and nurture one another along the way.
Title: Field Applications Scientist, remote Spain Location: Remote Spain Full time As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer. Location: remote Madrid or other large city in Spain Territory : Spain and Portugal DESCRIPTION: We are seeking a Field Applications Scientist to provide technical support and training for our analytical and scientific solutions. In this role, you'll collaborate with sales teams and customers to deliver demonstrations, applications support, and training that enables research and innovation. You'll serve as a scientific advisor, helping customers optimize their workflows and maximize the value of their investments while contributing to our mission of making the world healthier, cleaner, and safer. Working across multiple technology platforms, you'll provide comprehensive pre- and post-sales technical expertise, conduct product demonstrations, develop new applications, troubleshoot complex issues, and build relationships with customers. Your role will involve working with cross-functional teams including sales, marketing, R&D, and product management to ensure customer success and drive business growth through technical excellence. REQUIREMENTS: • Advanced Degree plus 3 years of experience, or Bachelor's Degree plus 5 years of experience with relevant analytical instrumentation and applications • Preferred Fields of Study: Chemistry, Biochemistry, Molecular Biology, or related discipline including proteomics, transcriptomics, genomics and qPCR. • Demonstrated expertise in technical problem-solving and method development • Clear written and verbal communication skills with ability to explain complex concepts to diverse audiences • Strong presentation and training capabilities for both technical and non-technical audiences • Ability to work independently and collaboratively in a results-oriented environment • Experience in project management and ability to handle multiple priorities • Willingness to travel up to 50-75% • Proficiency in Microsoft Office applications and relevant scientific software • Customer service orientation and interpersonal skills • Ability to build and maintain effective relationships with internal teams and external customers • Fluent English required; additional languages beneficial • Valid driver's license and passport required for travel
Research Assistant
Penn State UniversityPenn State is an equal opportunity employer and is committed to providing employment opportunities to all qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If you are unable to use our online application process due to an impairment or disability, please contact 814-865-1473. Penn State is committed to and accountable for advancing equity, respect, and belonging. We embrace individual uniqueness, as well as a culture of belonging that supports equity initiatives, leverages the educational and institutional benefits of inclusion in society, and provides opportunities for engagement intended to help all members of the community thrive. We value belonging as a core strength and an essential element of the university’s teaching, research, and service mission.
Role Description The Mathematics Department in the Eberly College of Science has a vacancy available for a Part-Time Research Assistant. The selected candidates will work with Professor Wenrui Hao in the research area of Computational modeling in biomedical diseases. - Work on data-driven modeling of biomedical diseases using machine learning and computational methods. - Review of applications will begin immediately and continue until the position has been filled. - Remote work is an option; you will not have to work in State College. Qualifications - Experience in machine learning and computational methods. - Background in biomedical research is preferred. Requirements - Successful completion of background check(s) in accordance with University policies. Benefits - Flexible work location (remote work available). Company Description Penn State is an equal opportunity employer and is committed to providing employment opportunities to all qualified applicants without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. - Commitment to advancing equity, respect, and belonging. - Embrace individual uniqueness and culture of belonging. - Support equity initiatives and provide opportunities for engagement.
Sr. Applied Scientist, Cedar Authorization
AmazonAmazon is the largest online retailer in the world. The Fortune 500 company offers traditional and e-books, household items, apparel, electronics, movies, music
Role Description Are you passionate about authorization, programming languages, applying formal verification, program analysis, constraint-solving, and/or theorem proving to real-world problems? Do you want to shape the future of an open-source authorization language that is becoming an industry standard? If so, then we have an exciting opportunity for you. Cedar is an open-source policy language and evaluation engine for authorization that is used across AWS services including Amazon Verified Permissions, AWS Systems Manager, and more. Cedar recently joined the Cloud Native Computing Foundation (CNCF) as a Sandbox project, and we are looking for an Applied Scientist to help advance Cedar's adoption, maturity, and community presence across the cloud-native ecosystem. In this role, you will drive the science and engineering behind Cedar's integration into cloud-native platforms such as Kubernetes, advance Cedar's formal verification and analysis capabilities, and serve as a technical leader and advocate within the CNCF community. You will interact with internal teams and external open-source communities to understand their authorization requirements, propose innovative solutions, create software prototypes, and productize prototypes into production systems. In addition, you will support and scale your solutions to meet the ever-growing demand of customer use. Key job responsibilities Technical Responsibilities - Drive the design and development of Cedar's integration into cloud-native authorization environments, including Kubernetes and other CNCF ecosystem projects. - Advance Cedar's formal verification, SMT-based analysis, and policy validation capabilities to raise the bar for authorization assurance. - Interact with various teams to develop an understanding of their security, authorization, and policy requirements. - Apply the acquired knowledge to build tools that find problems, or show the absence of security/safety problems, in authorization policies and systems. - Implement these tools through the use of SAT, SMT, and various concepts from programming languages, theorem proving, formal verification, and constraint solving. - Create software prototypes to verify and validate devised solutions; integrate prototypes into production systems using standard software development tools and methodologies. - Contribute to Cedar's open-source codebase as a maintainer, driving code quality, review standards, and technical direction. Leadership & Community Responsibilities - Represent Cedar and AWS at technical conferences, including CNCF events such as KubeCon, and advocate for Cedar adoption across the cloud-native community. - Can present and defend company-wide technical decisions to the internal technical community and represent the company effectively at technical conferences. - Functional thought leader, sought after for key tech decisions. Can successfully sell ideas to an executive-level decision maker. - Mentor and train the research scientist community on complex technical issues. - Collaborate with the open-source community to advance Cedar's CNCF project maturity (Sandbox → Incubation → Graduated). - Build and maintain relationships with cloud-native developers, contributors, and organizations to drive Cedar adoption and gather feedback. Qualifications - PhD, or Master's degree and 6+ years of applied research experience. - Experience programming in Java, C++, Python, Rust, Go, or related language. - Experience in any of the following areas: algorithms and data structures, parsing, numerical optimization, data mining, parallel and distributed computing, high-performance computing. - Experience in patents or publications at top-tier peer-reviewed conferences or journals. Requirements - 5+ years of industry or academic research experience. - Experience in professional software development. - Experience with authorization systems, policy languages, or access control frameworks (e.g., Cedar, OPA/Rego, RBAC/ABAC/ReBAC systems). - Experience contributing to or maintaining open-source projects, particularly within the CNCF or Kubernetes ecosystem. - Demonstrated community leadership in cloud-native or open-source communities (e.g., CNCF Ambassador, SIG/WG chair, conference speaker). - Experience with formal verification, SMT solvers, or automated reasoning applied to policy analysis or software correctness. - Familiarity with Kubernetes authorization architecture, admission control, or API machinery. - Track record of public speaking, technical advocacy, or developer relations at industry conferences. Company Description Amazon is an equal opportunities employer. We believe passionately that employing a diverse workforce is central to our success. We make recruiting decisions based on your experience and skills. We value your passion to discover, invent, simplify and build. Protecting your privacy and the security of your data is a longstanding top priority for Amazon. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit our accommodations page for more information.

