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Veracyte, Inc. logo
Veracyte, Inc.

High-value insights, high-impact decisions

Associate Director, Computational Development

DirectorDirectorFull TimeRemoteSeniorTeam 501-1,000Since 2013H1B No SponsorCompany SiteLinkedIn

Location

California

Posted

76 days ago

Salary

$192K - $208K / year

Seniority

Senior

Postgraduate Degree8 yrs expEnglishPythonSDLC

Job Description

Associate Director, Computational Development

Veracyte, Inc.

• Provide bioinformatics leadership for MRD assay design, development, and optimization across one or more LDT programs, ensuring alignment with scientific, clinical, and business objectives. • Serve as a senior scientific contributor and reviewer for assay concepts, signal detection strategies, error suppression approaches, and MRD calling methodologies. • Apply deep expertise in cancer genomics, ctDNA biology, and NGS technologies to guide assay architecture and analytical decision‑making. • Lead and/or oversee analytical study design and data analysis for assay development and validation, including accuracy, limit of detection, precision, and robustness. • Guide development, validation, and maintenance of scalable, production‑ready bioinformatics pipelines supporting MRD analysis, QC, and reporting. • Review and approve analytical approaches, benchmarking studies, and optimization strategies, ensuring scientific rigor and regulatory readiness. • Ensure compliance with standards (CAP/CLIA, FDA, IVDR) throughout the bioinformatics development lifecycle, including rigorous testing and documentation. • Provide day‑to‑day scientific mentorship and technical guidance to bioinformatics scientists and senior scientists. • Support career development of team members through coaching, technical review, and knowledge sharing. • Communicate complex analytical concepts clearly to stakeholders at varying levels of technical depth, including senior leadership.

Job Requirements

  • Ph.D. in Bioinformatics, Computational Biology, Genomics, Biostatistics, or a closely related quantitative field.
  • Minimum 8 years of total relevant experience, with at least 5 years of management experience in biotech, diagnostics, or regulated healthcare environments.
  • Demonstrated experience leading NGS‑based assay development for clinical diagnostics. Hands‑on experience with ctDNA‑based MRD assays, including personalized or tumor‑informed approaches.
  • Strong programming skills in Python, with experience developing and benchmarking reproducible, production‑grade analysis pipelines, including experience with SDLC best practices.
  • Proven experience working in design‑controlled, regulated environments (CAP/CLIA LDT, IVD, or equivalent) is a must.
  • Track record of working with wet lab scientists on iterative experiment design, execution, analysis, and interpretation as a tightly integrated team.
  • Demonstrated record of technical and scientific leadership, ownership, and independent work.

Benefits

  • Health insurance
  • Competitive compensation
  • Professional development opportunities
  • Flexible work arrangements
  • Inclusion in a diverse workforce

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