Title: Director, Channel Distribution Strategy Location: Boston, MA Full time job requisition id: REQ-27220 Job Description: Job Description Vertex currently operates at the forefront of rare disease scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Sickle Cell Disease, Transfusion-Dependent Beta Thalassemia and Acute Pain. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Diabetic Peripheral Neuropathy, Type 1 Diabetes, IgA Nephropathy (IgAN), APOL-1 Mediated Kidney Disease, and Muscular Dystrophy, among others. The Director, Channel Distribution Strategy is accountable for the design, implementation and evolution of channel distribution strategies across the organization’s portfolio in North America. This individual will lead strategic planning considering country-specific regulations and policies, program sustainability, strategic alliances, patient and customer access, data, class of trade and setting of care. They will inform distribution service agreement design to support maximum access and distribution efficiency. They will leverage access and reimbursement expertise and considerations across a variety of drug types spanning small molecule, specialty and cell and gene therapies. The ideal candidate combines deep pharmaceutical channel distribution expertise with strategic acumen, cross-functional leadership and the ability to navigate complex trade and emerging therapy models. Key Responsibilities - Serve as subject matter expert on evolving supply chain and distribution related laws, channel models, and strategic channel partner business models and capabilities across US and Canada - Maintain a deep understanding of the Hospital, Specialty & Retail pharmacy channels; understand pharmacy and hospital capabilities and the competitive marketplace to ensure Vertex maintains an industry leading approach to patient support in specialty channels. - Lead a team in designing scalable, innovative distribution strategies to maximize patient access and achieve corporate goals while considering financial impact, patient/ customer experience and strategic alliances - Support recommendation with strong analytics and consideration of channel economics, active and pending policy (e.g. serialization, importation, state and federal pricing policy, etc.), reimbursement, setting of care, financial implications and patient access dynamics - Collaborate with and ensure alignment across key stakeholders on channel distribution strategy development; Deliver recommendations to Senior Leadership and relevant, internal governing bodies and strategic teams - Partner with Trade team and functional business partners to support Vertex’s understanding of distribution capabilities, market expertise and differentiation - Partner with pipeline and inline strategy teams as well as trade team to generate insights and inform commercialization planning, including forecasting, gross-to-net and operational build considerations - Identify and define timely evolution of current Vertex distribution programs with a focus on new product launch, risk mitigation, changes in market dynamics, competition, organizational portfolio needs and/or regulatory and legislative changes - Exercise sound judgment in all activities to ensure integrity and compliance with company policies. Promote Vertex core values, leading by example, developing and fostering exceptional collaboration and promote enterprise thinking to drive breakthrough results Knowledge and Skills: - Expert knowledge of drug distribution channels including cell and gene therapy, specialty distribution, specialty pharmacy and retail. - Previous strategic leadership experience in the pharmaceutical/biotech or healthcare industry - Proven track record of meeting or exceeding objectives & goals, both as an individual and as part of a team - Proven ability to develop and lead strategic initiatives and projects both internally and with external consultant support. - Relevant experience with distribution networks, new product launches, trade processes, and understanding of pharmaceutical supply chain. - Demonstrated understanding of the US commercial and government healthcare and reimbursement environment, including product and fund flow, patient support and government programs - Excellent communication skills with experience presenting to customers and internal leadership - Demonstrated ability to successfully navigate cross-functional teams, influencing without direct authority, with the interpersonal skills to foster collaboration and succeed in a highly matrixed environment - Ability to perform in a fast-paced environment, manage multiple priorities simultaneously, and work effectively across cross-functional teams - Excellent analytical skills with solid understanding of trade channel data. Education and Experience: - Bachelor’s degree in relevant field, Master’s Degree preferred - Deep industry experience (10+ years) in commercial market access, trade and distribution - Previous channel distribution experience with cell and gene therapy, rare disease and small molecule Location: - HQ or Hybrid Schedule (3 days a week in HQ) - Ability and willingness to travel up to 20% of the time. Pay Range: $180,800 - $271,100 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Title: Assistant Director of Admissions, Cornell SC Johnson College of Business Location: Ithaca (Main Campus) Hybrid time type: Full time job requisition id: WDR-00057576 Job Description: Located in Ithaca, N.Y., Cornell University is a bold, innovative, inclusive, and dynamic teaching and research university where staff, faculty, and students alike are challenged to make an enduring contribution to the betterment of humanity. Cornell University is one of the largest and most diverse institutions in the Ivy League. We are a community of 22,000 students and more than 10,000 faculty and staff members representing more than 80 countries and hundreds of disciplines—global cultures, backgrounds, experiences, perspectives, and ideas. The Cornell SC Johnson College of Business comprises the university’s three accredited business schools: The Cornell Peter and Stephanie Nolan School of Hotel Administration, the Charles H. Dyson School of Applied Economics and Management, and the Samuel Curtis Johnson Graduate School of Management. The College delivers undergraduate, graduate, and professional business programs, creating a collaborative, comprehensive business management program that preserves the excellence of all three schools while uniting the faculty and students. The Cornell SC Johnson College of Business is one of the most comprehensive business schools in the nation, with 145 research faculty and nearly 2,900 undergraduate, professional, and graduate students. The College has a collection of areas of expertise not found in any other leading institution and an unparalleled resource base from which to draw—both within the Cornell SC Johnson College of Business and within Cornell University (including Cornell Tech). Enrollment representatives within Cornell’s colleges, schools, and units regularly collaborate and partner with the Enrollment Division to accomplish the University’s enrollment goals. The Office of Undergraduate and Specialized Master’s Programs Admissions plays a vital role in attracting high‑quality applicants to the SC Johnson College of Business. Each year, our undergraduate business programs draw approximately 8,000 applications, yielding nearly 500 new Cornell students. Our admissions team is collaborative, energetic, and deeply committed to identifying top‑tier talent while fostering an inclusive and welcoming community. Reporting to the Associate Director of Undergraduate Admissions, the Assistant Director of Admissions is responsible for implementing and leading off‑campus recruitment strategies for prospective undergraduate students. In partnership with the Associate Director, this role develops and executes recruitment plans that strengthen relationships with targeted high schools, community‑based organizations, and business‑focused academic programs to increase awareness of the College’s offerings. Key responsibilities include: - Implement and lead off‑campus recruitment strategies for prospective undergraduate students. - Build and maintain relationships with targeted high schools, community‑based organizations (CBOs), and business‑focused academic programs to increase awareness and applications. - Plan and manage outreach activities to engage high school students and cultivate interest in the SC Johnson College of Business. - Conduct 2–4 weeks of annual travel to priority regions for recruitment events and high‑school engagement. - Develop programs and outreach for guidance counselors and influencers who support targeted student populations. - Serve as co‑advisor to the Dyson and Nolan Student Ambassador programs. - Oversee recruitment, selection, training, and engagement for approximately 40 student ambassadors. - Support ambassador involvement in admissions events, recruitment, and yield activities. - Review 1,000+ undergraduate and transfer applications each year across a designated domestic and international territory. - Contribute to a culture of belonging by communicating across differences, demonstrating empathy and respect, and supporting a healthy, inclusive work environment. While position responsibilities vary, every member of our community is expected to foster a culture of belonging and a healthy work environment by communicating across differences; being cooperative, collaborative, open, and welcoming; showing respect, compassion, and empathy; engaging and supporting others regardless of background or perspective; speaking up when others are being excluded or treated inappropriately; and supporting work/life integration of oneself and others. Frequent travel (domestic and international) is required along with evening and weekend hours. Required Qualifications: - Bachelor’s Degree or equivalent with two to four years of work experience or equivalent combination. - Strong team orientation and ability to work effectively with prospective students, parents, faculty, senior staff, alumni, industry leaders, and outside organizations. - Outgoing, energetic individuals with excellent interpersonal, organizational and communication skills. - Position requires considerable independent judgement, decision making, and a high level of confidentiality. - Ability to plan and manage activities to an established budget, and to report on a regular basis. - Ability to travel and to plan travel for others. - Experience working directly with people from various socioeconomic backgrounds. - Experience incorporating the perspectives of multiple communities. - Ability to advocate for individuals from a broad range of backgrounds. - Ability to cultivate and develop inclusive working relationships with students, faculty, staff, and community members. Preferred Qualifications: - Direct experience in college recruitment, and/or college admissions - Experience with social media. - Proficiency with Microsoft Office tools, particularly Excel - Experience with Slate or PeopleSoft - Fluency in language other than English This is a full-time, 3-year fixed term, position based in Ithaca, NY that will offer hybrid work flexibility. Salary to commensurate with education and experience. Rewards and Benefits: - Cornell receives national recognition as an award-winning workplace for our health, wellbeing, sustainability, and diversity initiatives. - Our benefits programs include comprehensive health care options, generous retirement contributions, access to wellness programs, and employee discounts with local and national retail brands. - Follow this link to learn more about the Total Rewards of Working at Cornell: https://hr.cornell.edu/jobs/your-total-rewards. - Our leave provisions include three weeks of vacation and 13 holidays: Martin Luther King, Jr. Day, Memorial Day, Juneteenth, Independence Day, Labor Day, Thanksgiving and the day after, and an end of the year winter break from December 25-January 1. To offer greater flexibility for observing faiths and traditions we also offer two additional floating holidays. Learn more about our generous leave provisions: Holiday and Accrued Time Off | Working at Cornell - Cornell's impressive educational benefits include tuition-free Extramural Study and Employee Degree Program, tuition aid for external education, and Cornell Children's Tuition Assistance Program. Learn more about our extensive educational benefits: Education Benefits | Working at Cornell - Relocation assistance is not available for this position. - No visa sponsorship is available for this position. - This is a full‑time, three‑year fixed‑term position based in Ithaca, NY, with hybrid work flexibility. University Job Title: Admissions Associate II Job Family: Student Services Level: F Pay Rate Type: Salary Pay Range: $72,209.00 - $77,625.00 Remote Option Availability: Hybrid Non-Union Positions Noted pay ranges reflect the potential pay opportunity for each job profile. The hiring rate of pay for the successful candidate will be determined considering the following criteria: - Prior relevant work or industry experience - Education level to the extent education is relevant to the position - Unique applicable skills - Academic Discipline Union Positions The hiring rate of pay for the successful candidate will be determined in accordance with the rates in the respective collective bargaining agreement. To learn more about Cornell’s union wages, see Union Pay Rates. Current Employees: If you currently work at Cornell University, please exit this website and log in to Workday using your Net ID and password. Select the Career icon on your Home dashboard to view jobs at Cornell. Online Submission Guidelines: Most positions at Cornell will require you to apply online and submit both a resume/CV and cover letter. You can upload documents either by “dragging and dropping” them into the dropbox or by using the “upload” icon on the application page. For more detailed instructions on how to apply to a job at Cornell, visit How We Hire on the HR website. Notice to Applicants: Please read the required Notice to Applicants statement by clicking here. This notice contains important information about applying for a position at Cornell as well as some of your rights and responsibilities as an applicant. EEO Statement: Cornell welcomes students, faculty, and staff with diverse backgrounds from across the globe to pursue world-class education and career opportunities, to further the founding principle of “... any person ... any study.” No person shall be denied employment on the basis of any legally protected status or subjected to prohibited discrimination involving, but not limited to, such factors as race, ethnic or national origin, citizenship and immigration status, color, sex, pregnancy or pregnancy-related conditions, age, creed, religion, actual or perceived disability (including persons associated with such a person), arrest and/or conviction record, military or veteran status, sexual orientation, gender expression and/or identity, an individual’s genetic information, domestic violence victim status, familial status, marital status, or any other characteristic protected by applicable federal, state, or local law. Cornell University embraces diversity in its workforce and seeks job candidates who will contribute to a climate that supports students, faculty, and staff of all identities and backgrounds. We hire based on merit, and encourage people from historically underrepresented and/or marginalized identities to apply. Consistent with federal law, Cornell engages in affirmative action in employment for qualified protected veterans as defined in the Vietnam Era Veterans’ Readjustment Assistance Act (VEVRAA) and qualified individuals with disabilities under Section 503 of the Rehabilitation Act. We also recognize a lawful preference in employment practices for Native Americans living on or near Indian reservations in accordance with applicable law.

Title: AD, Global HEOR - Pain Location: Boston, MA Job Description: Job Description Full time job requisition id REQ-27745 Job Description General Summary: The Health Economics & Outcomes Research Associate Director will participate in leading the development and execution of Health economics and outcomes research studies in support of Vertex's products. Key Duties and Responsibilities: - Leads others to execute complex HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value - Gathers and synthesizes insights from Payers, KOLs and HEOR experts; stays current with scientific and policy trends and best practices and applies strategic and content expertise to strategy planning - Applies best practices to provide key input to the design of Vertex observational research studies - Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact - Partners and works closely with Global Pricing and Market Access to support production of GVD and Value Narrative Knowledge and Skills: - Strong track record of publication in peer-reviewed journals - Provides technical expertise in HEOR and is able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices - Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences - Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development, to identify evidence gaps and formulate evidence generation strategies - Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct Education and Experience: - Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline. - Typically requires 8 years of experience, with substantial background in HEOR, or the equivalent combination of education and experience Pay Range: $176,000 - $264,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Lead the development of analytics frameworks and dashboards, partner with stakeholders to enhance data quality, and build a high-performing team to drive insights and continuous improvement across quality governance and compliance.