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Natera logo
Natera

We are a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.

Vice President, Laboratory Software Engineering

Full-stack EngineerSoftware EngineerOtherRemoteLeadTeam 1,001-5,000Since 2004H1B SponsorCompany SiteLinkedIn

Location

California + 1 moreAll locations: California | Texas

Posted

100 days ago

Salary

$239.8K - $299.7K / year

Seniority

Lead

15 yrs expEnglish

Job Description

Vice President, Laboratory Software Engineering

Natera

• Define and own the enterprise laboratory informatics strategy spanning sample accessioning, order management, sample tracking, and workflow orchestration across wet labs, dry labs, and downstream data consumers. • Lead the modernization of a predominantly homegrown informatics landscape, including architectural redesign, platform consolidation, and technology standardization. • Drive strategic build-vs-buy decisions, including vendor evaluation, platform selection, and long-term ownership models. • Establish and execute a multi-year roadmap that supports enterprise growth, new product introductions, and evolving regulatory expectations. • Ensure informatics platforms reliably support high-throughput, mission-critical laboratory operations across Oncology, Women’s Health, and Organ Health portfolios. • Partner closely with laboratory operations, product, R&D, quality, and regulatory teams to optimize workflows, increase automation, and reduce operational friction. • Enable rapid onboarding of new assays and laboratory workflows while maintaining system stability, data integrity, and compliance. • Define and track KPIs related to system performance, availability, throughput, and operational efficiency. • Lead, mentor, and scale a high-performing organization of approximately 200 professionals across laboratory applications engineering, workflow platforms, data systems, validation, and operations support. • Build strong leadership bench strength and succession plans across a geographically distributed organization. • Foster a culture of technical excellence, accountability, customer focus, and continuous improvement. • Evolve organizational structures and operating models toward enterprise platforms rather than siloed, business-unit–specific systems. • Ensure informatics platforms meet regulatory and quality requirements, including CLIA, CAP, HIPAA, FDA-regulated diagnostics (including LDTs), and applicable GxP standards. • Establish policies and controls to ensure data integrity, traceability, security, and privacy across the laboratory informatics ecosystem. • Communicate platform strategy, risks, and tradeoffs clearly to executive leadership and other stakeholders. • Maintain strong relationships with laboratory users through regular engagement, including onsite interaction in San Carlos, CA and Austin, TX as needed.

Job Requirements

  • 15+ years of progressive experience in laboratory informatics, enterprise software platforms, or large-scale systems supporting regulated, mission-critical environments.
  • Demonstrated success leading large, complex organizations (100+ people), preferably at the VP or equivalent senior leadership level.
  • Deep understanding of laboratory workflows, including sample accessioning, order and sample tracking, and wet-lab and dry-lab orchestration.
  • Proven experience modernizing legacy or homegrown platforms, including leading major architectural transformations and build-vs-buy decisions.
  • Strong executive presence with the ability to influence across functions and communicate effectively with technical and non-technical stakeholders.

Benefits

  • Competitive compensation package, including base salary, performance-based incentives, equity participation, and comprehensive benefits.
  • Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.
  • Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.
  • Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more.
  • Generous employee referral program!

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