SOPHiA GENETICS

Do you have previous experience in either NGS Workflow products (Lab Prep, Equipment or Software) or Biotech sales? Are you passionate about selling a product with a true purpose? Bring your knowledge & passion to healthcare with SOPHiA GENETICS as our new Sales Executive for the Mid-Atlantic Region. You can be based anywhere in the territory. This is a field role, with 50-75% Travel. Why us: We believe there is a smarter, more data-driven way to make decisions in healthcare and our AI SaaS Platform enables that. You will have direct input into our mission to radically improve the outcomes for Cancer & Rare Disease patients globally. Enable our customers to push industry boundaries, as we pioneer into newly discovered fields and combine complex, multi-modal data for the first time! This is an opportunity for someone with passion to make their first healthcare move, or for someone with industry exposure to continue making a positive impact. Your mission: Reporting into the Senior Director, Sales - U.S. East, you will have autonomy for your territory, with the enablement and partnership from our customer success, service and support teams. You join us as we define and focus our team into Sales, Customer Success, SME and Sales Operations, meaning you will have more time to focus on what is important for you - prospecting, pitching and winning new business. The value you add - Prospecting, pitching and driving business development - Identifying and closing opportunities with new organizations - Drive consistent momentum in sales cycles and maintain a healthy sales pipeline - Collaborate with Customer Success to ensure effective, customer-focused onboarding - Advise the company and guide product management on market & product requirements Requirements The experience you bring - 3-5 Years of consultative sales experience - Experience of either: Selling NGS or Genomics products into Hospital Systems / Lab Environments OR wider commercial experience with enterprise software solutions - You don't need previous product knowledge within Genetics, Diagnostics or similar Health Analytics, but you must be hungry to learn about the subject matter - A hunter mentality, driven by a desire to consistently generate new business - You will need to be able to travel across your territory to a minimum of 50% Benefits You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth. Business recognition and accolades include: - World's most innovative companies (Top 10) - World's smartest companies (Top 50) - 100 Best Places to Work in Boston - Top 10 European Tech Startup - Top 10 European biotechs startup to watch - Top 25 East-Coast Biotech to watch Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview: US: Outstanding Medical, Dental & Vision with 90% Employer Contribution Company matched 401K at 4% Company-paid short & long-term disability insurance FSA commuter benefits 20 Days PTO, increasing to 25 with tenure; 5 Days Sick and 14 Public Holidays Free EAP Our DNA Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous Our Virtues At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn. At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal The Process We use the power of AI to help our partners make decisions. If you're utilizing AI in your search and application process, why not use some of these prompts, or read our AI guide. 'What impact can I expect to have on the world by working at SOPHiA GENETICS?' 'I have an interview with SOPHiA GENETICS. What should I know before I meet with them?' 'I am a *job title* - What can SOPHiA GENETICS offer my career?' Apply now with your CV and any supporting information. Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance. We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please. Starting Date: ASAP Location: Remote - Home Office in Territory Contract: Permanent MA Pay Range: $71,250 - $143,750 Disclaimer: The estimated pay range represents a good faith estimate of what the Company expects to pay a successful applicant for the listed position and applies specifically to candidates based in Massachusetts. Due to various factors, the estimated pay range may vary in other locations. Should the level or location of the role change during the hiring process, the applicable base range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual's qualifications, job related skills, years of experience, location, relevant education or training, internal equity, and alignment with market data. The range does not include benefits, and if applicable, bonus, commission, or equity.

• Prospecting, pitching and driving business development • Identifying and closing opportunities with new organizations • Drive consistent momentum in sales cycles and maintain a healthy sales pipeline • Collaborate with Customer Success to ensure effective, customer-focused onboarding • Advise the company and guide product management on market & product requirements

Do you have previous experience in either NGS Workflow products (Lab Prep, Equipment or Software) or similar Genomic Diagnostic Environments? Are you passionate about selling a product with a true purpose? Bring your knowledge & passion to healthcare with SOPHiA GENETICS as our new Senior Sales Executive for the Northeast. Ideally, this person will be based in either Boston or NYC. This is a field role, with 50-75% travel. Why us: We believe there is a smarter, more data-driven way to make decisions in healthcare and our AI SaaS Platform enables that. You will have direct input into our mission to radically improve the outcomes for Cancer & Rare Disease patients globally. Enable our customers to push industry boundaries, as we pioneer into newly discovered fields and combine complex, multi-modal data for the first time! Your mission: Reporting to the Senior Director of Sales, US East, you will have full ownership and autonomy to drive sales in your territory, with the enablement and partnership from our customer success, service and support teams. The value you add - Prospecting, pitching and driving business development. - Identifying and closing opportunities with new organizations. - Drive consistent momentum in sales cycles and maintain a healthy sales pipeline - Collaborate with Customer Success to ensure effective, customer-focused onboarding - Advise the company and guide product management on market & product requirements Requirements The experience you bring - 3-5 Years of consultative sales experience - Experience of either: Selling NGS or Genomics products into Hospital Systems / Lab Environments OR wider commercial experience with enterprise software solutions. - You don't need previous product knowledge within Genetics, Diagnostics or similar Health Analytics, but you must be hungry to learn about the subject matter. - A hunter mentality, driven by a desire to consistently generate new business. - You will need to be able to travel across your territory to a minimum of 50%. Benefits You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth. Business recognition and accolades include: - World's most innovative companies (Top 10) - World's smartest companies (Top 50) - 100 Best Places to Work in Boston - Top 10 European Tech Startup - Top 10 European biotechs startup to watch - Top 25 East-Coast Biotech to watch Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview: US: Outstanding Medical, Dental & Vision with 90% Employer Contribution Company matched 401K at 4% Company-paid short & long-term disability insurance FSA commuter benefits 20 Days PTO, increasing to 25 with tenure; 5 Days Sick and 14 Public Holidays Free EAP Our DNA Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous Our Virtues At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn. At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal The Process We use the power of AI to help our partners make decisions. If you're utilizing AI in your search and application process, why not use some of these prompts, or read our AI guide. 'What impact can I expect to have on the world by working at SOPHiA GENETICS?' 'I have an interview with SOPHiA GENETICS. What should I know before I meet with them?' 'I am a *job title* - What can SOPHiA GENETICS offer my career?' Apply now with your CV and any supporting information. Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance. We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please. Starting Date: ASAP Location: Remote - Home Office in Territory (NY/Boston) Contract: Permanent MA Pay Range: $88,000 - $168,000 Disclaimer: The estimated pay range represents a good faith estimate of what the Company expects to pay a successful applicant for the listed position and applies specifically to candidates based in Massachusetts. Due to various factors, the estimated pay range may vary in other locations. Should the level or location of the role change during the hiring process, the applicable base range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual's qualifications, job related skills, years of experience, location, relevant education or training, internal equity, and alignment with market data. The range does not include benefits, and if applicable, bonus, commission, or equity.

**The value you add** - Prospecting, pitching and driving business development. - Identifying and closing opportunities with new organizations. - Drive consistent momentum in sales cycles and maintain a healthy sales pipeline - Collaborate with Customer Success to ensure effective, customer-focused onboarding - Advise the company and guide product management on market & product requirements

Role Description Do you have previous experience in either NGS Workflow products (Lab Prep, Equipment or Software) or Biotech sales? Are you passionate about selling a product with a true purpose? Bring your knowledge & passion to healthcare with SOPHiA GENETICS as our new Sales Executive for NY/Boston. You can be based anywhere in the territory. This is a field role, with 50-75% Travel. Your mission: - Reporting into the Senior Director of Sales (US East), you will have autonomy for your territory, with the enablement and partnership from our customer success, service and support teams. - You join us as we define and focus our team into Sales, Customer Success, SME and Sales Operations, meaning you will have more time to focus on what is important for you – Prospecting, Pitching and winning new business. The value you add: - Prospecting, Pitching and driving Business Development. - Identifying and closing opportunities with new organizations. - Drive consistent momentum in sales cycles and maintain a healthy sales pipeline. - Collaborate with Customer Success to ensure effective, customer-focused onboarding. - Advise the company and guide product management on market & product requirements. Qualifications - 3-5 Years of consultative sales experience. - Experience of either: Selling NGS or Genomics products into Hospital Systems / Lab Environments OR wider commercial experience with enterprise software solutions. - A hunter mentality, driven by a desire to consistently generate new business. - You don't need previous product knowledge within Genetics, Diagnostics or similar Health Analytics, but you must be hungry to learn about the subject matter. - You will need to be able to travel across your territory to a minimum of 50%. Requirements - Joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth. Benefits - Outstanding Medical, Dental & Vision with 90% Employer Contribution. - Company matched 401K at 4%. - Company-paid short & long-term disability insurance. - FSA commuter benefits. - 20 Days PTO, increasing to 25 with tenure; 5 Days Sick and 14 Public Holidays. - Free EAP. Company Description - World's most innovative companies (Top 10). - World's smartest companies (Top 50). - 100 Best Places to Work in Boston. - Top 10 European Tech Startup. - Top 10 European biotechs startup to watch. - Top 25 East-Coast Biotech to watch.

Do you enjoy using your technical knowledge of Genomics & the NGS workflow coupled with commercial prowess coupled to provide credibility and technical insights during the customer sales journey? Do you have experience in APAC Markets? If this sounds like you and you are driven by purpose, Join the SOPHiA GENETICS APAC Sales Team as a Subject Matter Expert for APAC, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide. This is a field based role, working within the roles territory. You will spend you time working from home-office, or travelling across your territory for customer meeting, conferences and events. In most instances, we look for individuals already living in-territory, but welcome those actively relocating to the area. Ideally we will hire this individual in Singapore or Malaysia where we already have hubs of colleagues, but suitably skilled individuals will be considered across SE Asia. This role might suit someone in another support role, like a technical sales specialist or FAS, or a technical individual from the lab looking to make their first commercial/sales move. Our mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe. Your mission As a Subject Matter Expert you will support and enable our Sales Executives throughout the sales cycles with deep, technical knowledge of the SOPHiA GENETICS Products and Applications across the Genomics & NGS Workflow - and gain further exposure as we pioneer into multi-modal data. You will support activity across the SE Asia & APAC markets. Your responsibilities - Partner closely with Sales Executives as a product technical expert to support, drive and close sales opportunities. - Deliver platform demonstrations and in-depth presentations to customers and participate in trade shows, vendors shows and technical/promotional seminars. - Provide expert knowledge across the full range of SOPHiA GENETICS products and applications, including AI SaaS Solutions to manage and interpret NGS Biomarkers and Laboratory Preparation. - Gather and share competitive market intelligence and drive continuous product development in collaboration with Sales, Marketing and Product Management. Requirements To be best established for success in this role, you will bring: - BSc, MSc or PHd in a relevant field such as Genetics, Molecular Biology, Oncology or similar. - Previous working knowledge in a Commercial Technical support role linked to Genomics, including Field Applications Scientist, Clinical Application Consultant, Technical Specialist/Advisor or Subject Matter Expert within a Clinical Diagnostics, Biotech or Medical environment is highly sought. - Direct experience (Technical or commercial) with products throughout the NGS Workflow including wet lab molecular biology products is critical. - Comfortable in translating complex, technical vocabulary into simple terminology and the ability to communicate effectively with both commercial & technical stakeholders is essential. As a public organisation facing ongoing commercial growth, you will bring a success-orientated and solutions-focused mindset that embraces team collaborations, change, growth and inclusion. As an international organisation, English is our primary business language and you will need to bring full fluency in English. As part of your recruitment journey, you should expect to meet English-only speakers, so for best chances of success, you should include your CV in English. Non-English CVs have a high likelihood of being rejected at application stage. Benefits You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we drive exponential growth. Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us. Business recognition and accolades include: - World's most innovative companies (Top 10) - World's smartest companies (Top 50) - 100 Best Places to Work in Boston - Top 10 European Tech Startup - Top 10 European biotechs startup to watch - Top 25 East-Coast Biotech to watch Our DNA Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous Our Virtues At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn. At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal The process We use the power of AI to help our partners make decisions. If you're utilising AI in your search and application process, why not use some of these prompts: 'What impact can I expect to have on the world by working at SOPHiA GENETICS?' 'I have an interview with SOPHiA GENETICS. What should I know before I meet with them?' 'I am a *job title* - What can SOPHiA GENETICS offer my career?' Apply now with your CV and any supporting information. Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance. We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilise agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please. Starting Date: ASAP Location: Malaysia or Singapore (Prefered) Other SE Asia as relevant; Field/Remote Contract: Permanent

Are you an experienced IVD professional specializing in NGS-based IVD and CDx products? Ready to take on impactful new projects at the forefront of precision medicine? If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Bioinformatic Product Development team as our IVD Development & Validation Lead, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide. This is a hybrid (3 Days PW) opportunity connected to our corporate offices in Switzerland (Rolle). International relocation can be supported and this advert is for candidates actively looking to relocate to Switzerland. This role cannot be performed remotely from another country. Our Mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. SOPHiA GENETICS is the creator of SOPHiA DDM™, a cloud-based platform for analyzing complex multimodal data and generating insights that help healthcare institutions make faster, better informed decisions. We work primarily in oncology and inherited disorders, where integrating genomic and phenotypic data is critical for clinical decision-making, research, and drug development. Our data-sharing methodology connects researchers and clinicians globally, supporting a community-driven approach to precision medicine. Our mission is to democratize data-driven medicine and ensure that every patient has access to the best possible diagnosis. Your Mission SOPHiA GENETICS has a strong NGS platform, established pharma partnerships, and a track record of delivering CE-IVD certified products. We are now scaling our CDx and CTA portfolio and investing in the IVD development and validation expertise to match that ambition, including under the more demanding requirements of IVDR and FDA. This role sits within a cross-functional organization, working closely with colleagues across bioinformatics, NGS assay development, regulatory, and clinical operations. Depending on your background, you will own the validation program for one or more CDx/CTA projects or take broader technical ownership across the full development lifecycle, from assay and bioinformatics pipeline development through V&V and the full regulatory evidence package. We work with urgency and purpose to meet the demands of patients and our pharma partners. This means knowing what a study needs to demonstrate, designing it accordingly, and not adding work that does not contribute to that goal. It also means building processes and standards that hold up as the portfolio grows. The value you bring Validation - Own the design and execution of validation programs for NGS-based IVD and CDx products, covering analytical performance, clinical performance, usability, and stability. - Design studies that are fit for purpose: the right methodology, acceptance criteria, and statistical approaches based on what needs to be demonstrated and the applicable regulatory context, drawing on relevant guidance (CLSI, professional standards, etc) and your own experience. - Handle the statistical aspects of V&V studies across the full range of study types - you know the standard approaches, when to apply them, and how to establish defensible methods. You do not need to be a dedicated biostatistician, but you need a solid command of the standard approaches. - Produce DHF-ready documentation, written clearly enough to be reviewed without extensive back-and-forth. - Build reusable validation frameworks, templates, and SOPs that can be applied consistently across programs Technical project leadership (for more senior candidates) - Be accountable for the technical success of CDx/CTA development programs end-to-end, from assay and bioinformatics pipeline development through verification, validation, and submission-ready regulatory evidence. - Connect the development, validation, and regulatory sub-teams, to ensure efficient project delivery and effective project risk mitigation. - Define the regulatory evidence strategy in collaboration with the Regulatory Lead: what is required, what is sufficient, what is not needed. Diagnostics development processes - Design the processes and standards that allow a growing diagnostics portfolio to be delivered consistently and efficiently across programs. - Work closely with NGS scientists, bioinformaticians, regulatory, quality, and product colleagues across a highly cross-functional environment. - Contribute to developing IVD capability across the organization and mentoring junior scientists where relevant. Requirements Essential: - Hands-on experience developing and validating NGS-based IVDs in a clinical diagnostic or CDx context. - A thorough understanding of IVD analytical and clinical validation methodology: how to design studies that are fit for purpose, what guidance frameworks apply and when, and how to make and defend scope decisions. - Working knowledge of FDA IVD regulatory pathways (510(k), De Novo, PMA, CTA/IUO) and/or EU IVDR, sufficient to design a validation program that holds up under regulatory review. - Good working knowledge of statistics as applied to IVD V&V: familiar with the standard approaches across the main study types, and able to establish pragmatic, defensible methods. Deeper statistical expertise is a plus. - Experience working within design controls and contributing to a Design History File. - Clear, precise technical writing. Protocols and reports that are complete and reviewable without the need for extensive edits. A strong plus: - Experience in oncology diagnostics. - Experience on CDx programs developed in partnership with pharma, including CTA and IUO studies. - A track record of delivering V&V programs on tight timelines without compromising on what matters. - Experience building validation infrastructure in a scaling environment: SOPs, templates, frameworks. - Prior experience leading or mentoring assay development and validation scientists Benefits You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth. Business recognition and accolades include: - World's most innovative companies (Top 10) - World's smartest companies (Top 50) - 100 Best Places to Work in Boston - Top 10 European Tech Startup - Top 10 European biotechs startup to watch - Top 25 East-Coast Biotech to watch Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview: - Sickness and Accident coverage through Helsana - Meal Vouchers at 90CHF PM with our partner cafeteria - A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit/snacks - Free parking in an easy to access location - A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding - As our global HQ, you'll have direct interaction and exposure to senior leadership and our executive team locally Our DNA Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous Our Virtues At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn. At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal The Process We use the power of AI to help our partners make decisions. If you're utilising AI in your search and application process, why not use some of these prompts, or read our AI guide. 'What impact can I expect to have on the world by working at SOPHiA GENETICS?' 'I have an interview with SOPHiA GENETICS. What should I know before I meet with them?' 'I am a *job title* - What can SOPHiA GENETICS offer my career?' Apply now with your CV and any supporting information. Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance. We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please. Starting Date: ASAP Location: Rolle, Switzerland (Relocation) Contract: Permanent

Are you an experienced IVD professional specializing in NGS-based IVD and CDx products? Ready to take on impactful new projects at the forefront of precision medicine? If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Bioinformatic Product Development team as our IVD Development & Validation Lead, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.  This is a hybrid (3 Days PW) opportunity connected to our corporate offices in Switzerland (Rolle). International relocation can be supported and this advert is for candidates actively looking to relocate to Switzerland. This role cannot be performed remotely from another country. Our Mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. SOPHiA GENETICS is the creator of SOPHiA DDM™, a cloud-based platform for analyzing complex multimodal data and generating insights that help healthcare institutions make faster, better informed decisions. We work primarily in oncology and inherited disorders, where integrating genomic and phenotypic data is critical for clinical decision-making, research, and drug development. Our data-sharing methodology connects researchers and clinicians globally, supporting a community-driven approach to precision medicine. Our mission is to democratize data-driven medicine and ensure that every patient has access to the best possible diagnosis. Your Mission SOPHiA GENETICS has a strong NGS platform, established pharma partnerships, and a track record of delivering CE-IVD certified products. We are now scaling our CDx and CTA portfolio and investing in the IVD development and validation expertise to match that ambition, including under the more demanding requirements of IVDR and FDA. This role sits within a cross-functional organization, working closely with colleagues across bioinformatics, NGS assay development, regulatory, and clinical operations. Depending on your background, you will own the validation program for one or more CDx/CTA projects or take broader technical ownership across the full development lifecycle, from assay and bioinformatics pipeline development through V&V and the full regulatory evidence package. We work with urgency and purpose to meet the demands of patients and our pharma partners. This means knowing what a study needs to demonstrate, designing it accordingly, and not adding work that does not contribute to that goal. It also means building processes and standards that hold up as the portfolio grows. The value you bring Validation - Own the design and execution of validation programs for NGS-based IVD and CDx products, covering analytical performance, clinical performance, usability, and stability. - Design studies that are fit for purpose: the right methodology, acceptance criteria, and statistical approaches based on what needs to be demonstrated and the applicable regulatory context, drawing on relevant guidance (CLSI, professional standards, etc) and your own experience. - Handle the statistical aspects of V&V studies across the full range of study types - you know the standard approaches, when to apply them, and how to establish defensible methods. You do not need to be a dedicated biostatistician, but you need a solid command of the standard approaches. - Produce DHF-ready documentation, written clearly enough to be reviewed without extensive back-and-forth. - Build reusable validation frameworks, templates, and SOPs that can be applied consistently across programs Technical project leadership (for more senior candidates) - Be accountable for the technical success of CDx/CTA development programs end-to-end, from assay and bioinformatics pipeline development through verification, validation, and submission-ready regulatory evidence. - Connect the development, validation, and regulatory sub-teams, to ensure efficient project delivery and effective project risk mitigation. - Define the regulatory evidence strategy in collaboration with the Regulatory Lead: what is required, what is sufficient, what is not needed. Diagnostics development processes - Design the processes and standards that allow a growing diagnostics portfolio to be delivered consistently and efficiently across programs. - Work closely with NGS scientists, bioinformaticians, regulatory, quality, and product colleagues across a highly cross-functional environment. - Contribute to developing IVD capability across the organization and mentoring junior scientists where relevant.

Are you an experienced IVD professional specializing in NGS-based IVD and CDx products? Ready to take on impactful new projects at the forefront of precision medicine? If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Bioinformatic Product Development team as our IVD Development & Validation Lead, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.  This is a hybrid (3 Days PW) opportunity connected to our corporate offices in Switzerland (Rolle). International relocation can be supported and this advert is for candidates actively looking to relocate to Switzerland. This role cannot be performed remotely from another country. Our Mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. SOPHiA GENETICS is the creator of SOPHiA DDM™, a cloud-based platform for analyzing complex multimodal data and generating insights that help healthcare institutions make faster, better informed decisions. We work primarily in oncology and inherited disorders, where integrating genomic and phenotypic data is critical for clinical decision-making, research, and drug development. Our data-sharing methodology connects researchers and clinicians globally, supporting a community-driven approach to precision medicine. Our mission is to democratize data-driven medicine and ensure that every patient has access to the best possible diagnosis. Your Mission SOPHiA GENETICS has a strong NGS platform, established pharma partnerships, and a track record of delivering CE-IVD certified products. We are now scaling our CDx and CTA portfolio and investing in the IVD development and validation expertise to match that ambition, including under the more demanding requirements of IVDR and FDA. This role sits within a cross-functional organization, working closely with colleagues across bioinformatics, NGS assay development, regulatory, and clinical operations. Depending on your background, you will own the validation program for one or more CDx/CTA projects or take broader technical ownership across the full development lifecycle, from assay and bioinformatics pipeline development through V&V and the full regulatory evidence package. We work with urgency and purpose to meet the demands of patients and our pharma partners. This means knowing what a study needs to demonstrate, designing it accordingly, and not adding work that does not contribute to that goal. It also means building processes and standards that hold up as the portfolio grows. The value you bring Validation - Own the design and execution of validation programs for NGS-based IVD and CDx products, covering analytical performance, clinical performance, usability, and stability. - Design studies that are fit for purpose: the right methodology, acceptance criteria, and statistical approaches based on what needs to be demonstrated and the applicable regulatory context, drawing on relevant guidance (CLSI, professional standards, etc) and your own experience. - Handle the statistical aspects of V&V studies across the full range of study types - you know the standard approaches, when to apply them, and how to establish defensible methods. You do not need to be a dedicated biostatistician, but you need a solid command of the standard approaches. - Produce DHF-ready documentation, written clearly enough to be reviewed without extensive back-and-forth. - Build reusable validation frameworks, templates, and SOPs that can be applied consistently across programs Technical project leadership (for more senior candidates) - Be accountable for the technical success of CDx/CTA development programs end-to-end, from assay and bioinformatics pipeline development through verification, validation, and submission-ready regulatory evidence. - Connect the development, validation, and regulatory sub-teams, to ensure efficient project delivery and effective project risk mitigation. - Define the regulatory evidence strategy in collaboration with the Regulatory Lead: what is required, what is sufficient, what is not needed. Diagnostics development processes - Design the processes and standards that allow a growing diagnostics portfolio to be delivered consistently and efficiently across programs. - Work closely with NGS scientists, bioinformaticians, regulatory, quality, and product colleagues across a highly cross-functional environment. - Contribute to developing IVD capability across the organization and mentoring junior scientists where relevant.

Are you an experienced IVD professional specializing in NGS-based IVD and CDx products? Ready to take on impactful new projects at the forefront of precision medicine? If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Bioinformatic Product Development team as our IVD Development & Validation Lead, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.  This is a hybrid (3 Days PW) opportunity connected to our corporate offices in Switzerland (Rolle). International relocation can be supported and this advert is for candidates actively looking to relocate to Switzerland. This role cannot be performed remotely from another country. Our Mission We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. SOPHiA GENETICS is the creator of SOPHiA DDM™, a cloud-based platform for analyzing complex multimodal data and generating insights that help healthcare institutions make faster, better informed decisions. We work primarily in oncology and inherited disorders, where integrating genomic and phenotypic data is critical for clinical decision-making, research, and drug development. Our data-sharing methodology connects researchers and clinicians globally, supporting a community-driven approach to precision medicine. Our mission is to democratize data-driven medicine and ensure that every patient has access to the best possible diagnosis. Your Mission SOPHiA GENETICS has a strong NGS platform, established pharma partnerships, and a track record of delivering CE-IVD certified products. We are now scaling our CDx and CTA portfolio and investing in the IVD development and validation expertise to match that ambition, including under the more demanding requirements of IVDR and FDA. This role sits within a cross-functional organization, working closely with colleagues across bioinformatics, NGS assay development, regulatory, and clinical operations. Depending on your background, you will own the validation program for one or more CDx/CTA projects or take broader technical ownership across the full development lifecycle, from assay and bioinformatics pipeline development through V&V and the full regulatory evidence package. We work with urgency and purpose to meet the demands of patients and our pharma partners. This means knowing what a study needs to demonstrate, designing it accordingly, and not adding work that does not contribute to that goal. It also means building processes and standards that hold up as the portfolio grows. The value you bring Validation - Own the design and execution of validation programs for NGS-based IVD and CDx products, covering analytical performance, clinical performance, usability, and stability. - Design studies that are fit for purpose: the right methodology, acceptance criteria, and statistical approaches based on what needs to be demonstrated and the applicable regulatory context, drawing on relevant guidance (CLSI, professional standards, etc) and your own experience. - Handle the statistical aspects of V&V studies across the full range of study types - you know the standard approaches, when to apply them, and how to establish defensible methods. You do not need to be a dedicated biostatistician, but you need a solid command of the standard approaches. - Produce DHF-ready documentation, written clearly enough to be reviewed without extensive back-and-forth. - Build reusable validation frameworks, templates, and SOPs that can be applied consistently across programs Technical project leadership (for more senior candidates) - Be accountable for the technical success of CDx/CTA development programs end-to-end, from assay and bioinformatics pipeline development through verification, validation, and submission-ready regulatory evidence. - Connect the development, validation, and regulatory sub-teams, to ensure efficient project delivery and effective project risk mitigation. - Define the regulatory evidence strategy in collaboration with the Regulatory Lead: what is required, what is sufficient, what is not needed. Diagnostics development processes - Design the processes and standards that allow a growing diagnostics portfolio to be delivered consistently and efficiently across programs. - Work closely with NGS scientists, bioinformaticians, regulatory, quality, and product colleagues across a highly cross-functional environment. - Contribute to developing IVD capability across the organization and mentoring junior scientists where relevant.