Compass Pathways

Title: Senior Manager, Medical Affairs Operations (Fixed-Term Contract) Job Description: Company introduction: Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health. The Company is headquartered in London, UK, with offices in New York City in the US. We focus on developing novel treatments that have the potential to improve the lives of those who are suffering with mental health conditions and who are not helped by current treatments.   We are pioneering a new paradigm for treating mental health conditions focused on rapid and durable responses through the development of our investigational COMP360 synthetic psilocybin treatment, potentially a first in class treatment. COMP360 has Breakthrough Therapy designation from the US Food and Drug Administration (FDA) and has received Innovative Licensing and Access Pathway (ILAP) designation in the UK for treatment-resistant depression (TRD) due to the pressing unmet need in this area. We are currently in phase 3 for TRD, have completed phase 2 studies for both post-traumatic stress disorder (PTSD) and anorexia nervosa and are planning a further late-stage study in PTSD. We envision a world where mental health means not just the absence of illness but the ability to thrive. - Compass Pathways. Job overview: Compass Pathways’ organization is accelerating innovation to deliver greater impact for patients. With a project-led structure and a focus on collaboration, we’re building a future-ready team that thrives in dynamic biotech ecosystems. Joining Compass Pathways now means being part of an agile team committed to developing therapies that make a meaningful difference worldwide. You will support the VP in evaluating, tracking, and closing out IISs in close alignment with the IIS team. Based on an excellent understanding of the legal and regulatory requirements, the position will ensure that policies reflect the highest levels of ethics and compliance, that review of applications is based solely on scientific merit and alignment with prespecified scope, decisions are communicated in a timely manner, and that subsequent contracting and milestones are accomplished seamlessly. Location: Hybrid in our New York City office or remote in the East Coast. Reports to: VP, Pharmacovigilance and Clinical Safety. Duration: 6-month contract. Roles and responsibilities (Include but are not limited to): - Proactively share project status, issue escalation, and resolution; schedule meetings to facilitate cross-functional team discussions, decisions, issue resolution towards achieving project goals - Must be able to work in undefined, cross functional teams and determine goals, identify challenges and work to completion of project or program - Additional leadership to the broader team by having a positive, solutions-focused, innovative and collaborative mindset - Ensure compliant processes consistent with medical and promotional review guidelines, industry regulations, and internal SOPs - Support generation of reports, dashboards, and data insights to drive operational decision making - Act as the liaison between Investigator Initiated study (IIS) sites and internal cross functional teams - Facilitate IIS meetings with investigators as needed. Facilitate review of potential compliance related issues with the IIS leads for each function (Controlled drug licensing, issues related to contract and regulatory requirements, Controlled drug licensing issues including obtaining copies of controlled drug licenses/DEA licenses from the IIS PIs (if expired, obtain renewed license etc; ), follow up on IB submissions and approvals, oversight for return of unused drug for destruction as per CTA, etc) - Ensure that the Pharmacovigilance department and IIS sites are updated with monthly Safety Reports/inquiries from sites - Documentation of study communication for inspection and audit readiness - Provide support to IIS activities as needed Candidate Profile: - Bachelor’s Degree required or PharmD/PhD equivalent experience, advanced degree preferred - 7+ years of pharmaceutical/biotherapeutics industry experience - Experience in drug safety, pharmacovigilance, quality assurance and compliance requirements are desirable - 3+ years of Medical Affairs Leadership experience - Experience in biomedical research, study feasibility - Proven ability to influence and work successfully in a complex, global, matrix organization - Resourceful with the ability to effectively manage multiple workstreams and projects - High degree of analytical ability and conflict-resolution skills - Ability to initiate and lead large, cross-function projects and see it through to completion - Excellent communication and organizational skills - Thrives in a flexible, dynamic environment 【For NYC】Compensation Description (annually): Please note that the base salary range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, and work location. Base pay is one part of the Total Package that is provided to compensate and recognise employees for their work and any role at Compass, regardless of the location, is eligible for additional discretionary bonuses and equity. 【Base salary per annum】: $160,000 - $210,000 USD Benefits & Compensation: For an overview of our benefits package and compensation information, please visit "Working at Compass". Equal opportunities: Reasonable accommodation We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know. UK applicants We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability. US applicants Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law. Sponsorship: Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying. Data Privacy: All data is confidential and protected by all legal and data privacy requirements, please see our recruitment Privacy Notice to learn more about how we process personal data.

Title: Coordinator, Marketing Location: New York, United States Job Description: Company introduction: Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health. The Company is headquartered in London, UK, with offices in New York City in the US. We focus on developing novel treatments that have the potential to improve the lives of those who are suffering with mental health conditions and who are not helped by current treatments.   We are pioneering a new paradigm for treating mental health conditions focused on rapid and durable responses through the development of our investigational COMP360 synthetic psilocybin treatment, potentially a first in class treatment. COMP360 has Breakthrough Therapy designation from the US Food and Drug Administration (FDA) and has received Innovative Licensing and Access Pathway (ILAP) designation in the UK for treatment-resistant depression (TRD) due to the pressing unmet need in this area. We are currently in phase 3 for TRD, have completed phase 2 studies for both post-traumatic stress disorder (PTSD) and anorexia nervosa and are planning a further late-stage study in PTSD. We envision a world where mental health means not just the absence of illness but the ability to thrive. - Compass Pathways. Job overview: The Coordinator, Marketing supports the development and execution of integrated marketing activities that build awareness, enable launch readiness, and support commercial goals across Compass Pathways. This role supports the marketing team and partners closely with Commercial Operations, Medical Affairs, Legal, and external agencies to help deliver high-quality materials, campaigns, and events in a regulated environment. Location: Hybrid In our New York City office or remote in the East Coast, United States. Reports to: Senior Director, Site of Care Marketing. Roles and responsibilities (Include but are not limited to): - Support the planning and execution of marketing initiatives across brand, digital, congress, and field support channels - Coordinate timelines, workflows, and approvals for materials in partnership with internal stakeholders and external agencies - Help manage day-to-day marketing operations, including meeting coordination, briefing documents, project trackers, and budget administration - Assist with the development, review, and distribution of marketing materials to ensure accuracy, consistency, and compliance with internal review processes - Support event planning and execution for internal meetings, and field programs, including logistics, vendor coordination, and follow-up - Track campaign performance, summarize key metrics, and help prepare reports and presentations for cross-functional stakeholders - Maintain marketing calendars, asset libraries, and version control to support efficient execution and team alignment - Support launch readiness activities and contribute to process improvements that strengthen organization and execution quality - Candidate Profile: - Bachelor’s degree in marketing, communications, business, life sciences, or a related field - 2–4 years of experience in marketing, coordination, project management, or commercial operations, ideally within biotech, pharma, or another regulated environment - Strong organizational and communication skills, with the ability to manage multiple priorities and work effectively across cross-functional teams - Detail-oriented, proactive, and collaborative, with experience supporting agencies, vendors, events, or content approval workflows - Comfortable using Microsoft Office and other project management, CRM, or digital asset tools, with a strong interest in supporting launch readiness and marketing execution - Mission-aligned and motivated by Compass Pathways’ values and commitment to improving mental health - 【For NYC】Compensation Description (annually): Please note that the base salary range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, and work location. Base pay is one part of the Total Package that is provided to compensate and recognise employees for their work and any role at Compass, regardless of the location, is eligible for additional discretionary bonuses and equity. 【Base salary per annum】: $80,000 - $100,000 USD Benefits & Compensation: For an overview of our benefits package and compensation information, please visit "Working at Compass". Equal opportunities: Reasonable accommodation We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know. UK applicants We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability. US applicants Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law. Sponsorship: Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying. Data Privacy: All data is confidential and protected by all legal and data privacy requirements, please see our recruitment Privacy Notice to learn more about how we process personal data.

Role Description The Manager, Transactional Finance will lead the day-to-day management, optimization, and control of Accounts Payable (AP) and Accounts Receivable (AR) activities across Compass Pathways' UK and US operations. This role plays a key part in ensuring accurate, timely, and compliant transaction processing, while supporting strong working capital discipline and scalable finance operations in a growing international biotech company. Working closely with the wider Finance team and cross-functional stakeholders, you will combine hands-on operational ownership with process improvement, controls, and team development in line with Compass' culture and values. Location: Remote (East Coast, USA) or hybrid (NYC/NJ office or London). Reports to: Director, Financial Controller. Responsibilities - Lead the end-to-end Accounts Payable and Accounts Receivable processes across the business, ensuring transactions are processed accurately, efficiently, and in line with agreed timelines. - Oversee supplier onboarding, CLM to ERP reconciliations, 3PL management, invoice processing, payment runs, and employee expense reimbursement workflows. - Ensure compliance with US and UK laws and regulations surrounding vendors and customers, with specific reference to DCSCA and Sunshine Act Reporting. - Manage customer invoicing, cash application, collections, and the resolution of overdue balances across UK and US operations. - Own AP and AR close activities, including aging reviews, balance sheet reconciliations, and investigation of outstanding items. - Partner with budget owners and stakeholders to resolve supplier queries, payment issues, customer account matters, and process gaps in a timely manner. - Maintain and continuously improve Purchase to Pay and Order to Cash controls, including Delegation of Authority governance. - Drive process improvements and automation opportunities across transactional finance, leveraging systems such as NetSuite, Concur, Workday Adaptive, and Workiva where relevant. - Build, coach, and develop AP and AR capability as the organization grows, supporting scalable processes in a fast-moving, regulated environment. - Contribute to broader finance initiatives including systems enhancement, process harmonization, policy development, and ad hoc analysis as required. Qualifications - Proven experience in Accounts Payable and Accounts Receivable within a multi-entity or international Biotech. - Strong understanding of transactional finance processes, controls and reconciliations. - Experience supporting month-end close and balance sheet accounts. - Confident managing invoice queries, payment issues and customer account matters. - Experience with supplier onboarding, collections and cash application. - Demonstrated ability to improve processes and support automation initiatives. - Strong stakeholder management and communication skills. - Experience managing or mentoring team members is a plus. - Exposure to NetSuite, Concur, or Workiva is advantageous. - Experience in a fast-paced, regulated, or high growth environment is preferred. - Committed to Compass’s ethos and values. Benefits - Base salary range: $120,000 — $155,000 USD. - Individual total compensation may vary based on qualifications, skill level, competencies, and work location. - Eligible for additional discretionary bonuses and equity. Equal opportunities - We are committed to building a workplace where everyone’s wellbeing matters. - Reasonable accommodation during the interview process is available. - We do not discriminate based on race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability. Sponsorship Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying. Data Privacy All data is confidential and protected by all legal and data privacy requirements. Please see our recruitment Privacy Notice to learn more about how we process personal data.

Role Description The Senior Director, Field Patient Access will play a pivotal leadership role in shaping how patients access COMP360 therapy in the US. This leader will build and lead a high-performing field team of Patient Access Liaisons (PALs) that enables treatment sites, patients, and caregivers to successfully navigate the complex access, reimbursement, and operational pathways required to deliver COMP360 therapy. Success will require a leader who can operate effectively in ambiguity, build from the ground up, and partner seamlessly across Patient Engagement, Commercial, Market Access, Medical Affairs, Legal, and Compliance. The ideal candidate brings deep expertise in access and reimbursement, a strong track record of building and leading field teams, and a commitment to improving patient access in complex environments. They are equally comfortable setting strategy and rolling up their sleeves to solve problems in real time. Above all, this leader is patient-centered – recognizing that behind every process, policy, and workflow is a patient seeking access to care – and is motivated to build systems that enable safe, compliant, and meaningful treatment experiences. This position reports to the VP, Patient Engagement and will be a key contributor to launch readiness and long-term success. Qualifications - Bachelor’s degree required; advanced degree (MBA, MPH, PharmD or equivalent) preferred - 7+ years of leadership experience in patient services within the biopharmaceutical or life sciences industry. Experience in mental health or neuroscience is highly preferred - Significant experience in field reimbursement, patient access, or market access roles - Experience building and leading national field access teams with a deep understanding of: - Medical and pharmacy benefit reimbursement - Buy-and-bill and site-of-care dynamics - Prior authorization and payer processes - Patient-centric leader who integrates compassion with operational rigor - Experience supporting complex therapies (e.g., specialty, infusion, REMS products, or site-administered treatments) - Data-driven decision maker with expertise in KPI development and performance optimization - Soft Skills: Deep empathy, exceptional communication skills, cross-functional leadership, stakeholder management skills, and the ability to navigate sensitive topics with rigor and compassion Requirements - Design and implement the national field patient access strategy aligned to COMP360 launch objectives - Build and lead the Patient Access Liaison (PAL) organization, including hiring, onboarding, training, development, and performance management - Define field roles, territory design, ways of working cross-functionally, and engagement model across treatment sites - Enable treatment sites to operationalize COMP360 therapy including reimbursement education, coverage navigation, billing and coding support, and workflow implementation - Support sites through patient activation and early treatment delivery - Identify and mitigate operational barriers to site adoption and scalability - Ensure field team is equipped to support medical benefit coverage pathways, prior authorization requirements, claims submission and resolution, and payer policy interpretation - Partner with Market Access to provide field insights on payer dynamics and access barriers - Partner with other leaders in Patient Engagement on the patient journey operationalization and support model - Partner with Medical Affairs, Commercial, Compliance and Legal, and Commercial Operations on the operating model development and execution - Develop and deliver training for PALs on: reimbursement and access strategy, REMS requirements, therapy workflow and operations, and compliance and appropriate engagement - Establish KPIs for field effectiveness - Provide ongoing insights to leadership on patient insights, access barriers, site readiness, and launch execution Benefits - Base salary range: $220,000 — $290,000 USD - Additional discretionary bonuses and equity eligibility Equal opportunities - Reasonable accommodation during the interview process - Commitment to diversity and equality - No discrimination based on race, religion, color, nationality, gender, age, or disability

Role Description Our Director, Strategic Payer Accounts is responsible for driving and securing formulary access and coverage for COMP360 across Medicaid payers, as well as key Regional (Commercial and Medicare) payers ahead of and through launch. Reporting to the Senior Director, Strategic Payer Accounts, this individual is responsible for establishing and maintaining strategic and productive customer relationships, developing strategic account plans that support their efforts in translating the COMP360 value proposition into sustainable coverage wins, while partnering internally with Health Economics and Outcomes Research (HEOR), Medical Affairs, Government Affairs, and Commercial Operations to ensure payer strategies are fully executed with precision. Roles and Responsibilities - Strategic Payer Account Strategy and Execution: - Work closely with the Senior Director to develop and execute account strategies across Medicaid and key Regional (Commercial and Medicare) payers to drive optimal formulary positioning for COMP360 at launch and beyond. - Stay current with dynamic market forces, customer organizational changes, and policy changes at the state and federal level that impact Compass and/or payer customers, and incorporate those variables into proposed account strategies and tactics as necessary and appropriate. - Own strategic and tactical planning and prioritization for assigned payer accounts, profiling key decision-makers including Pharmacy Directors, Medical Directors, Clinical Pharmacy and Finance leads, and P&T committee members. - Own strategic relationships with payer customers and serve as the primary interface and negotiator for coverage and access discussions. - Identify and proactively address barriers to formulary inclusion, developing tailored strategies to support timely P&T reviews and coverage policy development. - Value Communication and Pull-Through: - Articulate the clinical and economic value proposition of COMP360 to payer audiences, integrating HEOR evidence, budget impact models, and real-world data to support coverage and access decisions. - Partner with the Senior Director and Finance on contracting recommendations to ensure proposals are commercially sound, aligned with government pricing compliance requirements, and GTN impacts are aligned with financial goals. - Collaborate closely with Directors of National Payer Accounts to develop and execute Regional pull-through initiatives following National formulary wins, and develop responsive strategies to address coverage challenges in complex or restricted downstream payer accounts. - Cross-Functional Collaboration: - Partner closely with HEOR, Medical Affairs, Government Affairs, Sales, Patient Engagement, and Patient Experience cross-functional partners to align payer specific push-or-pull-through strategies and tactics. - For Medicaid public P&T and DUR meetings, lead and execute a multi-prong strategy: - Collaborate with Sales and Patient Engagement to obtain HCP testimony, in person, virtually, or in writing. - Collaborate with HEOR and Medical to secure impactful manufacturer testimony at the meeting. - Collaborate with Government Affairs around any relevant legislative-related tactics. - Collaborate with Patient Experience regarding appropriate patient advocacy organization (i.e. NAMI, AfPA, etc.) support. - Collaborate with Sales, Patient Engagement, and Commercial Operations leadership on HCP-facing formulary and access update communications that enable effective Sales execution and pull through. - Represent the payer perspective internally, providing strategic guidance to leadership on coverage risks, opportunities, and competitive landscape dynamics. Qualifications - 7+ years in pharma/biotech market access, with significant direct experience in Medicaid and Regional payer account management. - Proven track record negotiating, securing, and maintaining formulary access for launch-stage (and beyond) specialty or breakthrough products; CNS/psychiatry or novel treatment modality experience is a plus. - Payer contracting experience, including Innovative contracting (e.g. value-based, outcome-based, volume-based, cap models) is a plus. - Deep knowledge of US payer landscape, formulary decision-making processes, utilization management, and prior authorization design. - Ability to translate HEOR and health economic data into compelling value narratives for payer audiences. - Hands-on launch experience at a growth-stage biotech; comfortable working in ambiguous situations and building tools and capabilities from scratch. - Exceptional stakeholder management skills; equally credible with external payer accounts and internal cross-functional partners. - Bachelor's degree required; advanced degree in Business, Public Health, Health Economics, or Pharmacy preferred. - Mission and values-aligned team player and cross-functional leader, passionate about expanding access to mental health innovation; demonstrates Compass' values: Compassion, Boldness, Inclusion, Rigour. Benefits - Base salary range: $220,000 — $270,000 USD. - Additional discretionary bonuses and equity eligibility for all roles. Equal Opportunities - Reasonable accommodation: We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know. - We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability.

Role Description Our Director, National Payer Accounts is responsible for driving and securing formulary access and coverage for COMP360 across national Commercial and Medicare payers and PBMs, ahead of and through launch. Reporting to the Senior Director, National Payer Accounts, this individual is responsible for establishing and maintaining strategic and productive customer relationships, developing strategic account plans that support their efforts in translating the COMP360 value proposition into sustainable coverage wins, while partnering internally with Health Economics and Outcomes Research (HEOR), Medical Affairs, Government Affairs, and Commercial Operations to ensure payer strategies are fully executed with precision. Roles and Responsibilities - National Payer Account Strategy and Execution - Work closely with the Senior Director to develop and execute account strategies across national Commercial and Medicare payer segments to drive optimal formulary positioning for COMP360 at launch and beyond. - Stay current with dynamic market forces, customer organizational changes, and policy changes at the state and federal level, that impact Compass and/or payer customers, and incorporate those variables into proposed account strategies and tactics as necessary and appropriate. - Own strategic and tactical planning and prioritization for assigned payer accounts, profiling key decision-makers including Pharmacy Directors, Medical Directors, Clinical Pharmacy and Finance leads, and P&T committee members. - Own strategic relationships with payer customers and serve as the primary interface and negotiator for coverage, contracting, and access discussions. - Identify and proactively address barriers to formulary inclusion, developing tailored strategies to support timely P&T reviews and coverage policy development. - Value Communication and Pull-Through - Articulate the clinical and economic value proposition of COMP360 to payer audiences, integrating HEOR evidence, budget impact models, and real-world data to support coverage and access decisions. - Partner with the Senior Director and Finance on contracting recommendations to ensure proposals are commercially sound, aligned with government pricing compliance requirements, and GTN impacts are aligned with financial goals. - Collaborate with Directors of Strategic Payer Accounts to develop downstream pull-through initiatives following national formulary wins. - Cross-Functional Collaboration - Partner closely with HEOR, Medical Affairs, Government Affairs, Sales, Patient Engagement, and Patient Experience cross-functional partners to align payer specific push-or-pull-through strategies and tactics. - Collaborate with Sales, Patient Engagement, and Commercial Operations leadership on HCP-facing formulary and access update communications that enable effective Sales execution and pull through. - Collaborate with Patient Experience regarding appropriate patient advocacy organization (i.e. NAMI, AfPA, etc.) support when needed. - Represent the payer perspective internally, providing strategic guidance to leadership on coverage risks, opportunities, and competitive landscape dynamics. Qualifications - 7+ years in pharma/biotech market access, with significant direct experience in National payer account management within the Commercial and Medicare payer segments. - Proven track record negotiating, securing, and maintaining formulary access for launch-stage (and beyond) specialty or breakthrough products; CNS/psychiatry or novel treatment modality experience is a plus. - Payer contracting experience, including innovative contracting (e.g. value-based, outcome-based, volume-based, cap models, etc.). - Deep knowledge of US payer landscape, formulary decision-making processes, utilization management, and prior authorization design. - Ability to translate HEOR and health economic data into compelling value narratives for payer audiences. - Hands-on launch experience at a growth-stage biotech; comfortable working in ambiguous situations and building tools and capabilities from scratch. - Exceptional stakeholder management skills; equally credible with external payer accounts and internal cross-functional partners. - Bachelor's degree required; advanced degree in Business, Public Health, Health Economics, or Pharmacy preferred. - Mission and values-aligned team player and cross-functional leader, passionate about expanding access to mental health innovation; demonstrates Compass' values: Compassion, Boldness, Inclusion, Rigour. Benefits - Base salary range: $220,000 — $270,000 USD. - Additional discretionary bonuses and equity eligibility for all roles. Equal Opportunities - We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know. - We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability. - Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law.

Role Description Our Director, Federal Payer Accounts is responsible for driving and securing formulary access and coverage for COMP360 across U.S. Federal healthcare systems, including Veteran's Administration (VA), Department of Defense (DoD), TriCare, and Indian Health Services (IHS) ahead of and through launch. Reporting to the Senior Director, Strategic Payer Accounts, this individual is responsible for establishing and maintaining strategic and productive customer relationships, developing strategic account plans that support their efforts in translating the COMP360 value proposition into sustainable coverage wins, while partnering internally with Health Economics and Outcomes Research (HEOR), Medical Affairs, Government Affairs, and Commercial Operations to ensure payer strategies are fully executed with precision. Roles and Responsibilities - Federal Payer Account Strategy and Execution: - Work closely with the Senior Director to develop and execute account strategies across VA, DoD, TriCare, and IHS payer segments to drive optimal formulary positioning for COMP360 at launch and beyond. - Stay current with dynamic market forces, customer organizational changes, and policy changes at the federal and state level that impact Compass and/or payer customers, and incorporate those variables into proposed account strategies and tactics as necessary and appropriate. - Own strategic and tactical planning and prioritization for assigned payer accounts, profiling key decision-makers including Pharmacy Directors, Medical Directors, Clinical Pharmacy and Finance leads, and P&T committee members. - Own strategic relationships with payer customers and serve as the primary interface and negotiator for coverage, contracting, and access discussions. - Identify and proactively address barriers to formulary inclusion, developing tailored strategies to support timely P&T reviews and coverage policy development. - Value Communication and Pull-Through: - Articulate the clinical and economic value proposition of COMP360 to payer audiences, integrating HEOR evidence, budget impact models, and real-world data to support coverage and access decisions. - Partner with the Senior Director and Finance on contracting recommendations to ensure proposals are commercially sound, aligned with government pricing compliance requirements, and GTN impacts are aligned with financial goals. - Collaborate with Sales and Patient Engagement on pull through initiatives in local VA/VISN and Military Treatment Facilities following national formulary wins. - Cross-Functional Collaboration: - Partner closely with HEOR, Medical Affairs, Government Affairs, Sales, and Patient Engagement to align payer specific push-or-pull-through strategies and tactics. - Where applicable and possible for P&T meetings, lead and execute a multi-prong strategy: - Collaborate with Sales and Patient Engagement to obtain HCP support. - Collaborate with Government Affairs around any relevant legislative-related tactics. - Collaborate with patient advocacy organizations (i.e. NAMI, AfPA, etc.) regarding appropriate support. - Collaborate with Sales, Patient Engagement, and Commercial Operations leadership on HCP-facing formulary and access update communications that enable effective Sales execution and pull through. - Represent the payer perspective internally, providing strategic guidance to leadership on coverage risks, opportunities, and competitive landscape dynamics. Qualifications - 7+ years in pharma/biotech market access, with significant direct experience in payer account management within the VA, DoD, TriCare, and IHS segments. - Proven track record negotiating, securing, and maintaining formulary access for launch-stage (and beyond) specialty or breakthrough products; CNS/psychiatry or novel treatment modality experience is a plus. - Experience executing contracts specific to the Federal payer market (i.e. Temporary Drug Pricing contracts, VA National Contracts, Provisional/Temporary pricing, etc.), as well as other innovative, outcome, and/or value based contracts. - Deep knowledge of US Federal payer landscape, formulary decision-making processes, utilization management, and prior authorization design. - Ability to translate HEOR and health economic data into compelling value narratives for payer audiences. - Hands-on launch experience at a growth-stage biotech; comfortable working in ambiguous situations and building tools and capabilities from scratch. - Exceptional stakeholder management skills; equally credible with external payer accounts and internal cross-functional partners. - Bachelor's degree required; advanced degree in Business, Public Health, Health Economics, or Pharmacy preferred. - Mission and values-aligned team player and cross-functional leader, passionate about expanding access to mental health innovation; demonstrates Compass' values: Compassion, Boldness, Inclusion, Rigour. Benefits - Base salary range: $220,000 — $270,000 USD. - Additional discretionary bonuses and equity eligibility. Equal Opportunities We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know. Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law.

Title: Senior Director, National Commercial Account Management Location: East Coast, United States; United States Job Description: Company introduction: Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health. The Company is headquartered in London, UK, with offices in New York City in the US. We focus on developing novel treatments that have the potential to improve the lives of those who are suffering with mental health conditions and who are not helped by current treatments.   We are pioneering a new paradigm for treating mental health conditions focused on rapid and durable responses through the development of our investigational COMP360 synthetic psilocybin treatment, potentially a first in class treatment. COMP360 has Breakthrough Therapy designation from the US Food and Drug Administration (FDA) and has received Innovative Licensing and Access Pathway (ILAP) designation in the UK for treatment-resistant depression (TRD) due to the pressing unmet need in this area. We are currently in phase 3 for TRD, have completed phase 2 studies for both post-traumatic stress disorder (PTSD) and anorexia nervosa and are planning a further late-stage study in PTSD. We envision a world where mental health means not just the absence of illness but the ability to thrive. - Compass Pathways. Job overview: Our Senior Director, National Commercial and Medicare Account Management is accountable for building and leading the national payer Account Director team, responsible for driving formulary access and coverage for COMP360 across national and regional payers and PBMs across Commercial and Medicare channels, ahead of and through launch. The right person should be both a strategic architect and hands-on relationship owner, responsible for translating the COMP360 value proposition into sustainable coverage wins, while partnering internally with HEOR, Medical Affairs, Government Affairs, and Commercial Operations to ensure payer strategies are fully executed with precision. Location: Remote on the East Coast in the United States or Hybrid in our New York City office Reports to: Senior Director, National Account Management. Roles and responsibilities (Include but are not limited to): National Payer Account Strategy and Execution - Work closely with the Senior Director to develop and execute national account strategies across commercial and Medicare payers and PBMs to drive optimal formulary positioning for COMP360 at launch - Stay current with market forces impacting and driving behaviors of payers and PBMs, and incorporate those variables into proposed account strategies as necessary and appropriate - Lead account-level planning and prioritization, profiling key payer decision-makers including Pharmacy Directors, Medical Directors, Clinical Pharmacy and Finance leads, and P&T committee members - Establish and own strategic relationships with national and regional payer accounts, as part of leading their team to serve as the primary interface for coverage, contracting, and access discussions - Identify and proactively address barriers to formulary inclusion, developing tailored strategies to support timely P&T reviews and coverage policy development Value Communication and Pull-Through - Articulate the clinical and economic value proposition of COMP360 to payer audiences, integrating HEOR evidence, budget impact models, and real-world data to support coverage and access decisions - Partner with the Senior Director, National Account Management on pricing and contracting strategy, ensuring payer proposals are commercially sound and aligned with government pricing compliance requirements - Lead team to execute pull-through initiatives following formulary wins and develop responsive strategies to address coverage challenges in complex or restricted downstream payer accounts Cross-Functional Collaboration - Partner closely with HEOR, Medical Affairs, Government Affairs, and Commercial Operations to align account strategies with the broader market access and commercial framework - Collaborate with Commercial Operations on field-facing payer communication tools, formulary grids, and access updates that enable effective sales execution - Represent the payer perspective internally, providing strategic guidance to leadership on coverage risks, opportunities, and competitive landscape dynamics Team and Capability Building - Build and lead a high-performing National Account Director team responsible for securing coverage by Commercial and Medicare payers and PBMs - Work with the Senior Director to establish operating rhythms, KPIs, and account reporting frameworks to track performance and ensure accountability across payer segments​ Candidate Profile: - 10+ years in pharma/biotech market access, with significant direct experience in national payer account management across commercial and Medicare payers and PBMs - Proven track record securing formulary access for launch-stage specialty or breakthrough products; CNS/psychiatry or novel treatment modality experience a strong plus - Deep knowledge of US payer landscape, formulary decision-making processes, utilization management, and prior authorization design - Ability to translate HEOR and health economic data into compelling value narratives for payer audiences - Hands-on launch experience at a growth-stage biotech; comfortable building function infrastructure including processes, tools, and teams from scratch - Exceptional stakeholder management skills; equally credible with external payer accounts and internal cross-functional partners - Bachelor's degree required; advanced degree in Business, Public Health, Health Economics, or Pharmacy preferred - Mission and values-aligned leader, passionate about expanding access to mental health innovation; demonstrates Compass' values: Compassion, Boldness, Inclusion, Rigour 【For NYC】Compensation Description (annually): Please note that the base salary range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, and work location. Base pay is one part of the Total Package that is provided to compensate and recognise employees for their work and any role at Compass, regardless of the location, is eligible for additional discretionary bonuses and equity. 【Base salary per annum】: $260,000 - $290,000 USD Benefits & Compensation: For an overview of our benefits package and compensation information, please visit "Working at Compass". Equal opportunities: UK applicants We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability. US applicants Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law. Sponsorship: Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying.

Title: Senior Statistical Programmer (Fixed-Term Contract) Location: New York, United States Job Description: Company introduction: Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health. The Company is headquartered in London, UK, with offices in New York City in the US. We focus on developing novel treatments that have the potential to improve the lives of those who are suffering with mental health conditions and who are not helped by current treatments.   We are pioneering a new paradigm for treating mental health conditions focused on rapid and durable responses through the development of our investigational COMP360 synthetic psilocybin treatment, potentially a first in class treatment. COMP360 has Breakthrough Therapy designation from the US Food and Drug Administration (FDA) and has received Innovative Licensing and Access Pathway (ILAP) designation in the UK for treatment-resistant depression (TRD) due to the pressing unmet need in this area. We are currently in phase 3 for TRD, have completed phase 2 studies for both post-traumatic stress disorder (PTSD) and anorexia nervosa and are planning a further late-stage study in PTSD. We envision a world where mental health means not just the absence of illness but the ability to thrive. - Compass Pathways. Job overview: The Senior Statistical Programmer will contribute expert programming skills to deliver accurate, regulatory-compliant clinical data outputs for Compass Pathways development programs. The role requires strong technical proficiency, collaboration across teams, and adaptability to support complex clinical trial requirements. Location: Hybrid in our NYC Office or remote in the East Coast. Reports to: Associate Director, Statistics and Data Management. Duration: 9-month contract. Roles and Responsibilities (Include but are not limited to): - Leading and coordinating the programming activities within agreed timelines - Managing the reporting of studies internally and externally - Programming outputs as stated in the analysis plan - Working closely with study team members, mainly with the study statistician - Reviewing of the Statistical Analysis Plan (SAP) and shells - Create and review SDTM and ADaM study specifications - Ensure programs, datasets, outputs are appropriate for regulatory submission - Perform simulations and data modelling - Perform Interim analyses - Liaise with external vendors on deliverables Candidate Profile: - Extensive years experience in statistical programming - CDISC expertise - Proficient in programming including performing statistical analyses and creating macros in SAS, preferably R - Programming/reporting expertise across all phases of clinical development (efficacy/safety/PK), including ISS/ISE reporting - Experience in performing quality control (QC) checks - Extensive knowledge in regulatory submission process - Good understanding of ICH guidelines and regulations such as 21 CFR Part 11 - Experience supporting NDA submissions e.g., FDA, EMA, MHRA and addressing regulatory questions - Ability to solve challenging problems and provide recommendations to mitigate risk - Good communication skills - both written and verbal - Team work skills - Including cross-functional and within the Statistics and Data Management Team Benefits & Compensation: For an overview of our benefits package and compensation information, please visit "Working at Compass". Equal opportunities: Reasonable accommodation We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know. UK applicants We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability. US applicants Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law. Sponsorship: Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying. Data Privacy: All data is confidential and protected by all legal and data privacy requirements, please see our recruitment Privacy Notice to learn more about how we process personal data.

Role Description The Regional Sales Director is a first-line sales leadership role responsible for building, developing, and leading a high-performing specialty sales team supporting the launch and growth of an innovative mental health therapy. This leader will drive regional execution of commercial strategy by partnering with certified treatment centers, psychiatrists, and integrated care systems while ensuring alignment with regulatory, safety, and patient-access frameworks. The Regional Sales Director will play a critical role in shaping a new therapeutic category, and creating a culture of integrity, collaboration, and patient-centricity. Location: Remote in Ohio (Cleveland/Columbus/Cincinnati, OH, Pittsburgh, PA). Reports to: Director, National Sales. Roles and Responsibilities - Recruit, onboard, and lead a team of Territory Account Managers - Foster a high-accountability, psychologically safe culture that promotes coaching, development, and collaboration - Set clear expectations and performance standards aligned with company launch objectives - Drive successful regional execution of the commercial launch strategy and identify opportunities to expand the treatment ecosystem - Ensure field readiness around clinical data, patient identification, treatment protocols, and site-of-care logistics - Foster strategic relationships with psychiatrists, treatment centers, behavioral health systems, academic centers, and Key Opinion Leaders (KOLs) - Partner cross-functionally with Medical Affairs, Market Access, Training, Patient Support, etc. - Provide field insights to inform brand strategy and launch optimization - Analyze regional performance metrics and develop action plans to drive results - Manage regional budgets, forecasting, and territory alignment - Conduct regular field coaching to strengthen clinical selling skills and consultative engagement with mental health providers Qualifications - Bachelor’s degree required (advanced degree preferred) - 8-10+ years of pharmaceutical or biotech sales experience - 5+ years of first-line sales leadership experience - Demonstrated success launching specialty or neuroscience therapies - Experience in psychiatry, CNS, or behavioral health markets - Experience launching therapies requiring site certification, REMS, or specialized administration models and/or a background working with IDNs, academic medical centers, and specialty treatment sites - Experience building teams in startup or pre-launch biotech environments Benefits - Base salary range: $180,000 — $230,000 USD - Eligible for additional discretionary bonuses and equity Equal Opportunities We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know. We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability. Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law. Sponsorship Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying. Data Privacy All data is confidential and protected by all legal and data privacy requirements, please see our recruitment Privacy Notice to learn more about how we process personal data.