BioMarin Pharmaceutical Inc.

• Manage specific accounts and customers in France • Provide appropriate updates of key medical and technical information to customers, including physicians, pharmacists, and nursing staff • Engage in marketing and promotional activities in accordance with country marketing plan • Oversee all activities related to the marketing and promotion of BioMarin’s products • Work with distributor and company headquarters on the establishment of new customers onto the ordering system • Develop and maintain strong customer contacts • Provide professional representation at medical meetings and conferences • Support the establishment of post-marketing surveillance studies as required

• Managing specific accounts and customers in France • Provide appropriate updates of key medical and technical information to customers, including physicians, pharmacists and nursing staff • Engage in marketing and promotional activities in accordance with country marketing plan and under the direction of the Sales Manager/Country Manager • Oversee all activities related to the marketing and promotion of BioMarin’s products in assigned territory • Work with distributor and company headquarters on the establishment of new customers on to the ordering system • Develop and maintain strong customer contacts • Provide professional representation at medical meeting and conferences • Provide in service disease/product training programs as needed for local medical staff • Support the establishment of post marketing surveillance studies as required (e.g., identifying potential sites) • Report any potential safety information within the timelines specified in the relevant SOPs to BioMarin Drug Safety following local and EMEA requirements • Other duties as assigned by the Sales Manager

• Drive access to Naglazyme, Vimizim and Brineura for patients in the assigned territory • Develop and maintain excellent working relationships with all key customers including: Geneticists, Pediatricians, KOLs, pharmacists, nursing staff, administrators from local Health Secretaries, business partners • Actively participate in business planning meetings and professional society meetings as assigned • Become an expert in the clinical data and be able to verbalize its significance to others • Provide insight to internal business partners as to the clinical practices of assigned accounts • Act in compliance and adhere to all company policies assigned to the Territory Manager positions • Achieve area sales, penetration and patient objectives, on a quarterly & annual basis

• Drive the monthly closing activities for the US region; and Amicus-related accounting and integration activities. • Oversight of monthly journal entries, account reconciliations, variance analyses and supporting schedules for SEC reporting and external audit requests. • Support contract reviews and reviews of other business transactions to determine the correct US GAAP Accounting, including providing proactive guidance to business partners and influencing business decisions. • Provide leadership and direction to teams supporting accounting operations, fostering accountability, continuous improvement, and consistent delivery of month-end close and reporting objectives. • Support process transformation, standardization, and enhancements, including acting as a key business partner in SAP S/4 HANA stabilization and Amicus integration activities. • Ensure internal controls are operating effectively. • Champion opportunities to improve accounting processes through the effective use of existing technologies, AI-enabled tools, automation capabilities, and emerging solutions.

• The Associate Director, Product Artwork Management leads the end-to-end product artwork capability across the product lifecycle • Define, scale, and implement a global printed-labelling (artwork) strategy and implementation process spanning the combined BioMarin product portfolio across all markets • Shape the multi-year roadmap for artwork capability, systems, and digital enablement • Establish, own and maintain the artwork governance framework, ensuring accurate, compliant, and inspection-ready artwork across the portfolio and all markets • Lead artwork planning and readiness for new product introductions and global launches, with integrated timelines aligned to regulatory and supply milestones • Manage the artwork lifecycle from concept to implementation—ensuring right-first-time quality and compliant, traceable operations

• Define and lead the enterprise CRM strategy and roadmap, ensuring alignment with CX goals, digital data strategy, and campaign needs. • Develop and implement a comprehensive CRM strategy that supports BioMarin’s business objectives and enhances customer engagement. • Define and prioritize CRM initiatives across Business Units and regions for efficient resource allocation and timely execution. • Oversee the entire CRM lifecycle, from requirements gathering to deployment, ongoing optimization, and future enhancements. • Collaborate with therapeutic area leads, digital peers, and their respective teams to ensure the CRM system supports unique business needs. • Act as a trusted advisor, guiding business units on leveraging CRM capabilities for customer engagement strategies. • Ensure CRM functionalities are aligned with business unit goals to maximize impact on sales and marketing. • Lead business ownership of CRM tools (including Veeva, Salesforce, and other key life sciences CRM systems), driving adoption, governance, and integration with omnichannel engagement platforms. • Ensure optimization of HCP and patient engagement via adaptation of segmentation, dynamic targeting, next-best-action logic, alerts / suggestions implementation, campaign tagging & attribution, and closed-loop measurement. • Ensure activation of fit for purpose CRM capabilities for cross-functional team engagement, task and targets management. • Partner with IT to define CRM business needs and ensure alignment with global Veeva/Salesforce standards. • Monitor key CRM metrics and identify areas for system performance improvement. • Collaborate with cross-functional teams (sales, marketing, medical) to ensure seamless integration of CRM strategies across departments.

Title: (CW) Sr. Study Specialist CONTRACT Job Description: Location: San Rafael, California Category: Research Employment Category: Fulltime-Temporary Description Who We Are BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions. Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions like achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and a number of forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, available options. More recently, with the close of the Amicus acquisition, our portfolio has expanded to include therapies for Fabry disease and Pompe disease, expanding our ability to reach more people living with rare genetic conditions. Our success comes from our unwavering commitment to excellence, our deep understanding of patient needs, our scientific expertise, and our world-class manufacturing capabilities. At the heart of BioMarin is a dedicated team of the brightest minds in the industry working together to deliver innovative therapies to patients and families around the world. About Worldwide Research and Development From research and discovery to post-market clinical development, our R&D engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating, and have few, if any, treatment options. BioMarin aims to improve life and health outcomes for people with rare diseases by advocating the use of innovative BioMarin therapeutics, advancing the standard of care, and providing personalized support and services globally. The BioMarin Global Study Operations function is tasked with providing strategic direction on the feasibility, design, and conduct of clinical studies and drives the delivery of high-quality data to support the registration and approval of clinical development assets. The function achieves this through the development and operationalization of Clinical Development Plans, study planning and delivery, cross-functional leadership of Study Execution Teams, operational trial expertise, and vendor management and oversight. CONTRACT Hybrid on Tues. and Thurs. in San Rafael or remote based employee within the US. *** Role Summary The Sr. Study Specialist (SS) significantly contributes to or leads tasks related to the oversight of site monitoring, vendor management, and other activities as delegated by the Study Manager or Program Lead (PL). This may include contributing to and/or supporting study related matters that impact study participant safety, data integrity, study timelines, quality, and budget. The Sr. SS will demonstrate a greater level of independence in executing assigned tasks and manage more challenging or complex vendors, sites, regions, including issue escalations from CROs and effective relationship management with Key Principal Investigator(s). Within the role, the candidate is expected to demonstrate and have proficient knowledge and experience in the following competencies: Core Competencies: ● .Agility and Proactivity ● .Leadership ● .Communication and Collaboration Technical Competencies: ● .Study Management and Execution ● .Compliance and Quality ● .Drug Development and Study Design ● .Product and Therapeutic Area Knowledge Responsibilities include but are not limited to: ● .Develop study specific documentation, as delegated by the Study Manager ● .Contribute to the oversight of country and site feasibility assessment and site selection. ● .Oversight of CRO for IRB/EC related submission/approval activities ● .Oversight of essential documents for study life-cycle management ● .Develop/Oversee site and investigator training materials ● .Present at investigator meetings as assigned ● .Ensure accurate and timely study entry and updates to ClinicalTrials.gov ● .Facilitate Screening Authorization Forms sign off and oversee tracking, where applicable ● .Process documents for signature in DocuSign ● .Oversight of Clinical Trial Insurance ● .Attend Global Study Operations team, vendor, and/or Cross-Function Study Execution Meeting(s) as GSO representative and take meeting minutes as requested. ● .Oversee and manage essential documents in the Trial Master File (TMF) ● .Contribute to Global Study Operations risks identification and mitigations. ● .Provide support and administrative assistance with internal and external meetings . Education & Experience ● .BA/BS or higher in nursing, life or health sciences is preferred.. Industry or relevant experience in lieu of education is considered. ● .Experience in a biotechnology or pharmaceutical company, oversight of external vendors including SOW, budgets, Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Role Description The PKU Sr. Account Manager is responsible for maximizing sales of BioMarin commercialized products in their area. They must maintain a high level of education on disease, promote awareness, and ensure compliance for patients on therapy. Good organizational, analytical, problem solving, and customer management skills are required. Demonstrated ability to gain the cooperation of others by utilizing excellent communication skills are required. Focus on coordination of care with excellent follow-up essential. Individual must be flexible and adaptable to new situations with sensitivity to the potential constraints of a “start-up” commercial organization. Must be goal oriented and know how to set aggressive but achievable targets. Instills a high standard of performance in the organization. Responsibilities - Achieve territory sales goals, penetration, market share, and profit targets on a quarterly & annual basis. - Create and implement an effective business plan to guide strategy, disease awareness, patient compliance, and track progress throughout the year. - Develop and maintain excellent working relationships with all key customers including: Geneticists, Nurses, Nurse Practitioners, Genetic Counselors and ancillary staff. - Proficient communication with external customers and internal stakeholders both in person as well as via internet-based platforms. - Provide leadership through example to fellow PKU Account Managers. - Financially manage assigned territory. - Actively participate in business planning meetings, disease awareness efforts, and professional society meetings as assigned. - Become an expert in PKU data and be able to verbalize its significance to others. - Provide field insight to internal business partners as to the clinical practices of assigned accounts. - Demonstrate leadership within internal teams, with ability to influence without authority. - Act in compliance and adhere to all company policies assigned to the PKU Account Manager. SCOPE - Ability to manage a multi-state territory with diverse customer base. Travel - Overnight travel is required and will range from 40%-60% depending on the geography and business needs of the individual territory. - This is a remote position. Territory: ND, SD, MN, WI (4 states) Remote Selling - Remote/virtual selling is required. Candidates must possess the ability to communicate with customers through internet-based meeting platforms. - Virtual selling activities include clinic meetings, internal account team calls and patient education meetings. Education - Bachelor’s degree required. - Advanced educational degree or experience in the Healthcare field desired (i.e., nurse, pharmacist, dietitian). Experience - Required minimums: - 7+ years of experience in the Pharmaceutical or Healthcare industries. - 5+ years of experience in biotech/specialty sales involving high cost products. - Highly desired: - Sales experience within hospitals and academic institutions. - Prior work with orphan-disease products. - Experience in new product launches.

• Develop and ensure timely execution of the scientific communication plans for BioMarin’s programs in Fabry disease and Pompe disease • Contribute to development and implementation of scientific messaging and maintain the Scientific Communication Platforms • Ensure cross-functional alignment of messaging and strategies to address gaps • Develop expert knowledge of product- and disease-specific literature and oversee literature and gap analyses to support scientific message development and publication strategy • Organize and implement expert meetings necessary for publication strategy development; collaborate with colleagues and external experts to develop agenda and content, manage vendors, and attend and present as needed • Facilitate the external/independent development of treatment and management guidelines • Research, draft, and edit scientific and medical manuscripts, abstracts, posters, and presentations • Manage agency and/or contract medical writers and/or graphic designers, as needed • Ensure all scientific communications outputs meet the highest standards of medical/scientific integrity • Ensure activities adhere to authorship and publication guidelines as stipulated by ICMJE and GPP 2022 • Assist with maintenance and reconciliation activities within publication development database • Respond to internal and external questions about any scientific communications for the product areas • Participate in cross-functional team meetings to share scientific communication planning status and issues, and maintain awareness of overall scientific communication plan • Provide support for management of the Scientific Communications budget

• Serve as the authoritative QC SME for analytical methods, specifications, and QC data supporting external manufacturing • Define QC technical requirements and performance expectations for external laboratories • Lead risk-based assessments of QC capabilities across CMOs/CTOs/CDMOs, including analytical technologies, method lifecycle maturity, and data integrity practices • Ensure external QC activities are aligned with regulatory expectations and internal quality standards • Provide Quality oversight for analytical method lifecycle activities including validation, verification, transfer, and lifecycle management at external sites • Lead or oversee method transfer strategies and execution readiness, ensuring robustness and comparability across sites • Partner with Analytical Sciences (e.g., APTL/APL) to support method lifecycle management, continuous improvement, and issue resolution • Ensure consistency of analytical methods and documentation across external sites in alignment with internal and regulatory standards • Establish and maintain QC performance monitoring frameworks across external laboratories • Lead statistical trending and analysis of QC metrics and signals, including, system suitability performance, invalid assay rates, method variability and drift • Utilize data to identify emerging risks, drive continuous improvement, and inform oversight strategies • Author and review QC sections of regulatory submissions (e.g., BLA, MAA, IND), ensuring scientific integrity and consistency • Support health authority inspections and responses, including defense of analytical methods and data • Ensure alignment of external QC practices with global regulatory expectations (FDA, EMA, ICH) • Represent External QC in cross-functional governance forums, including QC Network Strategy (QCNS), Analytical/Quality Partner Teams (APT/QPT) • Provide input into external laboratory selection, make vs. buy decisions, analytical control strategies • Provide technical SME leadership for QC-related investigations, including OOS/OOT and method performance issues • Lead or support root cause analysis and define technically sound corrective actions • Partner with internal QC and Analytical Sciences teams to ensure appropriate qualification, lifecycle management, and use of reference standards and critical reagents at external laboratories • Provide QC SME support during audits and inspections, ensuring technical practices are consistent with QMS requirements • Experience leading cross-functional teams and influencing technical decisions without direct authority