Role Description The MSL will serve as a field-based scientific expert responsible for engaging with healthcare professionals (HCPs), supporting clinical development, and ensuring alignment with Centessa’s strategic medical objectives. This role is critical in translating complex scientific data into meaningful clinical insights and fostering compliant, evidence-based dialogue with thought leaders. Key Responsibilities - Scientific Expertise & Thought Leader Engagement - Maintain a high level of therapeutic area expertise and scientific knowledge relevant to Centessa’s pipeline and marketed products in alignment with Medical Affairs strategic objectives. - Engage in compliant, non-promotional scientific exchange with key opinion leaders (KOLs), investigators, and other HCPs. - Serve as a trusted scientific resource to external stakeholders, providing accurate and balanced medical information. - Deliver company-approved, high-quality medical/scientific presentations to a variety of audiences including formulary committees and healthcare professionals. - Provide medical/scientific support for critical Centessa activities including speaker training, advisory boards, and sales training as appropriate. - Ensure accurate, timely, and compliant documentation of field-based activities in accordance with MSL organization guidelines. - Clinical Trials Support - Collaborate with Clinical Operations to identify and evaluate potential clinical trial sites and investigators based on scientific expertise, patient population, and alignment with study objectives. - Provide scientific education and protocol-specific training to investigators and site staff during site initiation visits, ensuring thorough understanding of study rationale and endpoints. - Maintain ongoing engagement with trial sites and investigators to facilitate successful execution of clinical trial objectives, provide ongoing scientific support, address protocol-related inquiries, and ensure high-quality data generation. - Medical Conference Attendance & Coverage - Attend relevant scientific and medical congresses to stay current with emerging data and trends. - Provide real-time insights and post-conference reports to internal teams. - Support Centessa’s presence at congresses through development of pre-conference plans, booth coverage, symposia participation, and KOL engagement. - Scientific Materials Development - Contribute to the development of scientific slide decks, FAQs, and educational materials. - Writing and editing Medical Information response letters. - Ensure all materials are medically accurate, evidence-based, and compliant with regulatory standards. - Collaborate with Medical Affairs and Legal teams to ensure scientific content meets internal and external guidelines. - Additional responsibilities may include but are not limited to: - Leading MSL strategic initiatives/projects aligned with Medical Affairs and MSL organization strategy. - Develop and implement scientific training plans for the MSL team. - Mentorship of MSL peers. Qualifications - Advanced degree (PhD, PharmD, MD) in life sciences or a related field (from an accredited college or university). - Minimum of 2 years of experience in a Medical Affairs or MSL role within the pharmaceutical or biotech industry. - Excellent understanding of sleep medicine and associated therapeutic areas strongly preferred. - Exceptional verbal and written communication skills; ability to tailor scientific messages to diverse audiences and ability to interpret and communicate complex scientific data. - Proven ability to build and maintain strong relationships with KOLs, investigators, and internal stakeholders. - Strong understanding of clinical trial design, regulatory requirements, and therapeutic area landscape. - Skilled in developing and delivering scientific presentations in various settings. - Strong understanding of industry regulations and guidelines governing medical interactions. - Ability to align field activities with broader medical and corporate strategies. - Must have a valid driver’s license with a driving record that meets company requirements. - Willing and able to travel frequently throughout the Southeast region including Alabama, Arkansas, Florida, Georgia, Louisiana, Mississippi, South Carolina, Tennessee with primary coverage of major metropolitan and academic medical center markets across the region. - Must reside in the Atlanta metropolitan area or a major Florida metropolitan area with access to a major commercial airport to support frequent travel throughout the Southeast territory. Work Location The Medical Science Liaison, Southeast is a remote role based in the US, with up to 60-70% travel and occasional weekends. Compensation The annual base salary range for this position is $175,000 to $215,000. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, and job knowledge. In addition to base pay, this role is eligible for a discretionary annual bonus. Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program. POSITION Full-Time, Exempt EEOC Statement Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. We will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.

Role Description The Medical Director at LumiMeds will be responsible for the clinical integrity and oversight of our telehealth platform. This role involves setting clinical protocols, supervising providers, and ensuring the highest standard of patient care. You will collaborate with key teams to build scalable care systems while maintaining compliance with regulations. Responsibilities - Serve as the senior clinical authority, accountable for patient care quality and safety - Develop and refine clinical protocols for weight management and metabolic health - Recruit, onboard, and supervise providers, ensuring consistency and safety in prescribing - Ensure compliance with federal and state regulations, including telehealth and prescribing laws - Monitor clinical outcomes and lead root-cause analysis for complex cases - Embed clinical safety checks into the platform and ensure accurate patient-facing content - Support credentialing of new providers and provide clinical input on new markets - Track and report key clinical metrics to leadership and the Board Qualifications - MD or DO with an active, unrestricted medical license in at least one U.S. state (multi-state licensure preferred) - Board certification in a relevant specialty (e.g., internal medicine, family medicine, endocrinology, obesity medicine) - 7+ years of clinical practice experience, with leadership or medical director experience - Experience supervising nurse practitioners, physician assistants, or a distributed provider network - Knowledge of telehealth regulations, interstate licensure, and controlled substance prescribing - Strong analytical and written communication skills - Comfortable working in a fast-paced startup environment How to Apply If this role sounds like a fit, we’d love to hear from you. Please submit your application in English and ensure your resume reflects relevant experience for the role. This position is open to candidates based in approved locations, depending on the role and business needs. Qualified applicants will be contacted for next steps. LumiMeds is an equal opportunity employer. We hire based on skills, experience, and alignment with our values. Please note: This role requires professional-level English communication and availability to work U.S. business hours.

• Responsible for the relevance and accuracy of clinical development planning and guidance for a clinical study. • Contribute to authoring and lead design/reviews of key product and study-related documents and deliverables. • Responsible for the oversight of clinical study execution as clinical lead. • Works with investigative sites and/or study teams to answer protocol related questions. • Reviews clinical data listings, patient profiles and summaries to ensure data collection, data interpretation and data reporting proceeds in a manner consistent with the protocol. • Prepare and may present protocol designs, clinical data and other information at advisory boards, investigator meetings, site initiations and other internal and external settings. • Supports regulatory interactions and the development of clinical sections for regulatory correspondence and submissions.

• Manages a team of Scientific Associates and/or Associate Medical Directors, ensuring standards are adhered to and work is timely and of the highest quality for appropriate agency representation • Validates, supports, and increases the clinical and medical relevance of work across the agency, including existing client accounts and new business endeavors • Performs in-depth research and builds understanding of a brand's placement within the treatment paradigm, its efficacy and safety data, mechanism of action, and key points of differentiation within the treatment landscape • Directly accountable for medical strategy input in the overall brand planning efforts of the agency, in collaboration with Brand Strategy and Engagement Strategy, as well as providing ongoing support throughout the new business pitch prep process • Ensures scientific and medical accuracy in both internal and external communications • Onboards agency staff to respective brand teams • Collaborates internally with Account, Strategy, Project Management and Creative departments, and with clients daily • Presents educational and strategic information to large groups both internally and during client and new business presentations, which may include individuals with a broad spectrum of backgrounds and education levels