• Provide scientific and strategic leadership across multiple accounts, aligning with brand goals and client objectives • Drive the development of medical strategies and contribute to the overall brand planning process in collaboration with Brand Strategy and Engagement teams • Oversee and validate the clinical and medical relevance of deliverables to ensure they are scientifically accurate and impactful • Serve as a key medical point of contact for clients, fostering trust and credibility through expertise and communication • Present educational and strategic content during client and new business presentations to diverse audiences • Support new business initiatives by contributing to pitch preparation and client proposals • Mentor and guide junior medical team members, including Scientific Associates and Associate Medical Directors, to foster professional growth • Ensure the quality and timeliness of work delivered by the team, adhering to agency and client standards • Onboard new team members to brand-specific knowledge and agency processes • Perform in-depth research to build a comprehensive understanding of therapeutic areas, including safety data, mechanisms of action, and treatment paradigms • Contribute to the development of educational materials and ensure alignment with client strategies • Stay updated on emerging clinical data, industry trends, and guidelines to inform team strategies • Collaborate with internal departments, including Account, Strategy, Project Management, and Creative, to integrate medical insights into deliverables • Partner with external stakeholders to enhance the relevance and value of the agency’s scientific offerings • Identify opportunities to innovate and improve processes within the medical department

• Report to the CMO, with a dotted-line relationship to the SVP of Research & Early-Stage Product Development • Serve as the clinical lead for Phase 1 retina clinical trials, including study design, protocol development, dose escalation strategy, and safety oversight • Maintain accountability for study execution, data interpretation, and clinical readouts, including early signal detection and go/no-go recommendations • Serve as medical monitor for assigned studies, ensuring subject safety and data integrity • Lead cross-functional study teams (clinical operations, clinical science, biometrics, regulatory, safety, CMC, etc.) to ensure high-quality and timely trial delivery • Provides clinical leadership to multidisciplinary study execution teams drawn from clinical operations, clinical science, biometrics, regulatory affairs, CMC, pharm/tox, drug safety, commercial, and alliance partners • Has lead accountability on the study teams for delivery of study protocols, study conduct, and study readouts • Lead development and implementation of biomarker strategies for GA and broader retina programs • Collaborate with research and translational teams to identify, validate, and integrate imaging, molecular, and functional biomarkers into early-phase trials • Ensure biomarkers are aligned with mechanism of action, dose selection, and clinical endpoints to support decision-making and regulatory strategy • Serve as the primary clinical author of development plans, protocols, IBs, INDs, CSRs, and regulatory responses • Lead clinical contributions to IND submissions and early regulatory interactions, including Health Authority meetings for Phase 1 programs • Ensure accuracy, scientific rigor, and regulatory compliance of all clinical documents • Organizes and leads scientific advisory board meetings. Interacts with external experts and stakeholders to gather input. • Works with the research organization and the portfolio management team to identify and support new project opportunities. • Collaborates to identify program risks, and to create and implement mitigation strategies • Other duties as assigned

• Providing Migraine therapeutic area/product expertise for stakeholders • Planning and executing independent Medical strategies and engagements • Maintaining up-to-date knowledge of relevant TA/disease states and Pfizer medicines • Serving as a resource for Medical Information and stakeholder insights • Educating stakeholders based on patient care gaps • Achieving leadership-defined expectations regarding external medical stakeholder engagement

• Shape Functional Strategy for Clinical • Own the Portfolio Roadmap • Build the clinical governance framework with the CMO • Stand up incident management end to end • Design credentialing and licensing infrastructure • Construct the regulatory operating system with General Counsel • Own the Member and MD Experience • Develop and Own the Team • Capacity Planning