• Lead quality oversight activities related to method validation, release and in-process testing for Drug Substance and Polysaccharide. • Serve as the primary liaison within Vaxcyte QA and with outside collaborators, building partnerships that support analytical needs for relevant programs. • Represent QA at internal and external cross functional team meetings. • Lead review and approval of internal and external GMP documentation for compliance, including specifications, Certificates of Analysis, validation reports, deviations, change controls, risk assessments, and CAPAs as they relate to polysaccharides and drug substance; apply technical and compliance expertise to critically evaluate reference standards, test methods, protocols, and raw data packages from CMOs and contract testing laboratories. • Partner with QC, vendor management, and contract labs to set key performance indicators for monitoring vendor effectiveness. • Drive resolution of quality performance issues with contract manufacturers and testing organizations. • Review Quality Agreements and regulatory documentation as required. • Lead quality investigations of testing deviations and OOS. • Contribute to regulatory filings, respond to questions from health authorities, and ensure quality of documentation used in support of regulatory submissions. • Take part in audit preparations and help ensure ongoing readiness. • Develop, review, and update GMP-related internal policies and procedures as necessary. • Champion a culture of quality excellence and continuous improvement by proactively identifying systemic gaps, driving implementation of sustainable solutions, and establishing performance standards that elevate GMP compliance across internal teams and external partners.

• Design, build, and maintain automated test frameworks for Commerce's Salesforce org — covering Apex unit tests, UI automation, API testing, and end-to-end regression suites. • Integrate automated test execution into CI/CD pipelines using GitHub Actions and SFDX-based deployment workflows, ensuring quality gates are enforced on every deployment to production. • Define and own test strategy across the SDLC — from story acceptance criteria and test plan authorship through execution, defect triage, and sign-off. • Investigate defects systematically: reproduce, isolate, categorize by impact, and produce minimum viable test cases that prevent recurrence. • Identify test coverage gaps across Apex classes, flows, integrations, and UI — and close them proactively rather than reactively. • Build and maintain test data management strategies that support reliable, repeatable test execution across sandbox environments. • Partner with developers on code reviews with a quality lens — flagging testability concerns, missing coverage, and brittle patterns before they reach production. • Own and evolve the team's quality dashboard, surfacing coverage metrics, defect trends, error rates, and deployment health to the broader team. • Participate in agile ceremonies, contribute to story refinement, and advocate for acceptance criteria that are specific enough to test. • Champion a culture of quality — not as a gate at the end of the process, but as a shared responsibility built into every stage of delivery.

• Collaborate with product managers, developers, and other QA to translate requirements into comprehensive black-box test plans. • Design and develop intricate test cases leveraging advanced black-box testing techniques (e.g., equivalence partitioning, state transition testing, combinatorial testing). • Craft robust test automation frameworks utilizing industry-leading tools (e.g., Playwright, Cypress) to achieve high test coverage and efficiency.

• Collaborate with product managers, developers, and other QA to translate requirements into comprehensive black-box test plans. • Design and develop intricate test cases leveraging advanced black-box testing techniques (e.g., equivalence partitioning, state transition testing, combinatorial testing). • Craft robust test automation frameworks utilizing industry-leading tools (e.g., Playwright, Cypress) to achieve high test coverage and efficiency.