Title: Senior Manager, Commercial Training and Development Location: United States Job Description: Overview The Senior Manager, US Commercial Training & Development – TTR Franchise reports to the Associate Director. This role involves developing and implementing capability building strategies, plans and processes that drive measurable field performance and business outcomes within the TTR franchise. The Training Manager will collaborate cross-functionally in a matrix organization with commercial leadership, field force, marketing, access, headquarters teams, medical, legal, and external vendors. This collaboration will involve facilitating group discussions to determine the training needs and deliverables for US commercial team members. Key Responsibilities - Support the design and execution of capability-building strategies that align to TTR Franchise business priorities and drive measurable field performance outcomes - Translate business goals into targeted learning strategies and solutions that enhance field effectiveness across the customer journey - Partner with Commercial Leadership and cross-functional stakeholders (Marketing, Market Access, Medical, Patient Services, and Operations) to identify performance gaps and define capability needs - Act as a trusted advisor, contributing to decisions related to field execution, capability development, and training strategy - Design and deliver high-impact learning experiences (live, virtual, and digital) that prioritize application, practice, and behavior change over knowledge transfer - Ensure learning solutions are scalable, efficient, and minimize time out of territory while maximizing impact - Manage the development and execution of new hire onboarding and continuous learning programs, ensuring readiness, confidence, and sustained performance in role - Contribute to building just-in-time learning approaches that support ongoing development and field application - Support and operationalize the Field Trainer model, enabling Field Trainers to operate as an extension of the CT&D team through strong facilitation, coaching, and in-field execution - Provide guidance, tools, and support to ensure consistent, high-quality delivery of learning initiatives - Leverage data, insights, and field feedback to assess capability gaps, measure training effectiveness, and recommend improvements to learning strategies - Track and report on key performance indicators (KPIs) to demonstrate the impact of training on behavior change and business outcomes - Design, develop, and deploy learning materials and assets, ensuring alignment with brand strategy, clinical accuracy, and compliance requirements - Manage the CRB submission process and ensure all training materials meet legal, regulatory, and medical standards - Apply innovative learning approaches and technologies (e.g., simulations, AI-enabled tools, digital platforms) to enhance engagement, retention, and scalability - Manage multiple learning initiatives and projects simultaneously, ensuring strong execution, clear communication, and alignment across stakeholders - Collaborate with cross-functional teams to support National Sales Meetings (NSM), POA meetings, and other key field engagements, ensuring learning is impactful and aligned to business priorities - Manage vendor relationships and project deliverables, ensuring high-quality, cost-effective execution of learning solutions - Demonstrate a strong understanding of commercial strategy, sales operations, and field tools, ensuring training solutions are practical, relevant, and aligned to how the field operates - Qualifications - Bachelor’s degree required - Must have a minimum of 5 years of experience in the Pharmaceutical Industry, Commercial field sales experience preferred - Preferred to have a minimum of 2 years training experience in a headquarters role or as a field trainer - - Proven ability to translate business strategy into capability-building plans that drive measurable outcomes - Demonstrated experience supporting product launches, complex therapeutic areas, or specialty markets preferred - Strong understanding of clinical data and the ability to translate scientific concepts into clear, compelling learning experiences - Demonstrated ability to influence cross-functional stakeholders and senior leaders in a highly matrixed environment - Strong executive presence with the ability to facilitate both strategic discussions and engaging learning experiences - Experience using data, insights, and performance metrics to identify capability gaps and measure training effectiveness and business impact - Strong foundation in adult learning principles, instructional design, and modern learning approaches, including digital, virtual, and just-in-time learning - Experience leveraging innovative learning solutions (e.g., simulations, AI-enabled tools, scalable learning platforms) preferred - Excellent project management skills with the ability to manage multiple priorities, workstreams, and deadlines in a fast-paced environment - Strong written and verbal communication skills, including presentation and facilitation excellence - Ability to build trusted relationships and collaborate effectively across all levels of the organization - Proficiency in Microsoft Office (PowerPoint, Excel, Word) and virtual learning platforms (e.g., Zoom or similar) - Ability to travel up to 20% - #LI-SS1 #LI-Remote U.S. Pay Range $147,100.00 - $198,900.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Title: Practice Transformation Coach Department Value-Based Care Programs Employment Type Full Time Location Maryland, USA Workplace type Fully remote Compensation $80,000 - $90,000 / year Job Description: The Practice Transformation Coach serves as a strategic advisor and subject matter expert responsible for driving clinical quality improvement and operational performance across provider practices within Astrana’s value-based care network in the Maryland and Northern Virginia (DMV) region. This role is primarily accountable for analyzing practice performance, identifying gaps, and developing and implementing targeted transformation strategies that improve quality outcomes, financial performance, and operational efficiency. The Coach exercises independent judgment and discretion in assessing practice needs, prioritizing interventions, and recommending solutions that align with organizational and value-based care objectives. Working directly with physicians, practice leadership, and care teams, this role influences decision-making, guides workflow redesign, and ensures effective adoption of population health and performance improvement strategies across a diverse provider network. Our Values: - Put Patients First - Empower Entrepreneurial Provider and Care Teams - Operate with Integrity & Excellence - Be Innovative - Work As One Team What You'll Do Practice Engagement & Coaching - Serve as a strategic advisor to provider practices, assessing clinical, operational, and financial performance and identifying opportunities for improvement - Exercise independent judgment in prioritizing practice engagements and determining the most effective intervention strategies based on performance data and business impact - Develop and lead execution of customized transformation plans to improve quality metrics, operational workflows, and financial outcomes Workflow Design & Optimization - Lead the design and implementation of workflow redesign initiatives, including EHR optimization, clinical documentation, and billing practices - Diagnose root causes of quality and financial underperformance and develop targeted, data-driven solutions - Provide guidance to providers and care teams to support adoption of optimized workflows and sustainable operational improvements Data Analysis & Performance Improvement - Analyze and interpret complex performance data, including HEDIS, pay-for-performance metrics, and medical cost trends, to inform strategic recommendations - Translate data insights into actionable performance improvement strategies tailored to individual practices and market needs - Monitor progress against established goals and adjust strategies as needed to ensure performance targets are achieved Cross-Function Leadership & Influence - Partner with internal stakeholders across Market Operations, Quality, and Population Health to ensure alignment on performance improvement initiatives - Influence provider and practice-level decision-making through data-driven insights, education, and consultative engagement - Serve as a key liaison between provider practices and organizational leadership to escalate risks, share insights, and drive alignment Continuous Improvement & Thought Leadership - Identify trends and systemic opportunities across practices to inform broader market-level or enterprise performance strategies - Contribute to the development of best practices, tools, and frameworks that enhance practice transformation efforts across the network - Support special projects and strategic initiatives aligned with value-based care performance goals Qualifications - Bachelor’s degree in nursing, healthcare administration, business, public health, or related field, or equivalent combination of education and progressively responsible experience - Equivalent combination of education and progressively responsible experience may be considered - 3+ years of analysis or provider/medical operations experience, preferably in the healthcare or managed care industry - Experience in value-based care, practice transformation, or quality improvement initiatives preferred - Demonstrated experience analyzing performance data and developing actionable, data-driven strategies - Experience working directly with provider groups, physicians, or clinical teams preferred - License/Certifications (if applicable): Licensed Vocational Nurse (LVN), Registered Nurse (RN), Certified Professional Coder (CPC) license preferred, Certified Professional in Healthcare Quality (CPHQ), Master of Health Administration (MHA), Master of Public Health (MPH), Project Management Professional (PMP), or Lean/Six Sigma (Green or Black Belt) certification preferred - Demonstrated ability to exercise independent judgment and discretion in evaluating performance data and recommending business-critical solutions - Strong understanding of value-based care models, population health, and healthcare quality improvement methodologies - Advanced analytical skills with the ability to interpret complex datasets and translate findings into actionable strategies - Strong business and financial acumen, including understanding of quality metrics, cost drivers, and performance incentives - Ability to influence provider behavior and drive change through consultative and relationship-based approaches - Excellent communication and presentation skills, with the ability to engage physicians, care teams, and leadership - Strong project management skills with the ability to manage multiple high-impact initiatives simultaneously - Proficiency in EHR systems and healthcare data tools - Ability to work independently in a dynamic, fast-paced environment Environmental Job Requirements and Working Conditions - This role operates in a hybrid, field-based environment supporting provider practices across the Maryland and Northern Virginia (DMV) region. The Practice Transformation Coach is expected to independently plan and prioritize onsite engagements with physician practices, care teams, and provider organizations to drive clinical and operational performance improvement. The position requires regular local travel (approximately 50–70%) within the assigned region to conduct onsite assessments, facilitate workflow redesign, and support implementation of value-based care initiatives. Travel is primarily regional and may involve driving to multiple practice locations within a given week. When not in the field, the role supports remote work activities, including performance data analysis, development of improvement strategies, preparation of reports, and virtual collaboration with internal stakeholders and provider partners. The Company reserves the right to modify the work arrangement, including travel expectations or transitioning the role to a more onsite-based structure, based on business needs and operational priorities. Disclaimer: This job description is intended to describe the general nature and level of work performed. It is not intended to be an exhaustive list of all responsibilities, duties, or qualifications required. Responsibilities may change based on business needs and organizational priorities. - The national target pay range for this role is $80,000 - $90,000. Actual compensation will be determined based on geographic location (current or future), experience, and other job-related factors. Astrana Health is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. All employment is decided on the basis of qualifications, merit, and business need. If you require assistance in applying for open positions due to a disability, please email us at humanresourcesdept@astranahealth.com to request an accommodation. Additional Information: The job description does not constitute an employment agreement between the employer and employee and is subject to change by the employer as the needs of the employer and requirements of the job change.

• Lead field coaching strategies that improve execution quality, customer engagement, and commercial performance. • Partner with field leadership to identify performance gaps and implement targeted coaching actions. • Provide candid, actionable feedback that supports individual and team development. • Design and deliver franchise-specific training content, tools, and learning pathways aligned to business priorities. • Coach and develop RSTs and other training partners to strengthen facilitation, coaching, and business impact. • Partner with Sales Leadership, Marketing, and other cross-functional teams to align training priorities with business strategy.

• Lead field coaching strategies that improve execution quality, customer engagement, and commercial performance. • Partner with field leadership to identify performance gaps and implement targeted coaching actions. • Provide candid, actionable feedback that supports individual and team development. • Reinforce consistent coaching expectations and execution standards across the field organization. • Design and deliver franchise-specific training content, tools, and learning pathways aligned to business priorities. • Build and facilitate training for onboarding, reinforcement, national meetings, and capability-building sessions. • Coach and develop RSTs and other training partners to strengthen facilitation, coaching, and business impact. • Partner with Sales Leadership, Marketing, and other cross-functional teams to align training priorities with business strategy. • Evaluate training effectiveness through feedback, performance metrics, and field outcomes.