• Lead provider implementations from contract execution through successful go-live. • Provide operational leadership, mentorship, and ongoing support for Advanced Practice Providers (APPs). • Coordinate provider onboarding, credentialing milestones, EMR access, orientation, training, and start readiness. • Serve as the primary operational liaison between providers, facility leadership, and internal departments. • Partner with recruiting, credentialing, scheduling, billing, payroll, and medical leadership to ensure seamless execution. • Build and maintain strong relationships with hospitals, inpatient rehabilitation facilities, skilled nursing facilities, and post-acute care partners. • Identify operational challenges, implement process improvements, and drive successful outcomes across multiple facilities. • Promote provider engagement, satisfaction, and retention through proactive communication and support. • Must be willing to Travel

• Develop and execute accurate operational development plans for assigned clinical trials, aligning with budget, timelines, and standard operating procedures (SOPs) • Oversee the management of clinical studies, including compliance with corporate, regulatory, and quality standards. • Lead clinical operations personnel, contract research organizations (CROs), consultants, core laboratories, and other study support organizations. • Handle program-level activities as assigned, ensuring operational plans are implemented effectively. • Ensure adherence to ICH-GCP, GPP, Incyte SOPs, and applicable country-specific regulations. • Work cross-functionally with internal teams (e.g., Medical Affairs, Medical Science Liaisons, Medical) and external partners to support trial goals and timelines. • Monitor site performance, feasibility, and study execution for assigned trials.

• Provide therapeutic and operational expertise throughout the program and project delivery lifecycle • Ensure that projects within the franchise are properly resourced • Collaborate with the therapeutic team to create effective delivery strategies and solutions for franchise projects and programs • Act as the main contact person for the Project Management Franchise Lead • Present at proposal defense and client meetings as needed to support new or ongoing business • Ensure CRAs are trained on project specifics • Ensure Lead CRAs (LCRAs) are trained to support the clinical scope of work, including standard operating procedure (SOP) review, quality issue (QI)/corrective and preventive action (CAPA) understanding, and the Clinical Monitoring Plan • Coordinate and collaborate with Worldwide Clinical Trials Global Quality Assurance to provide training opportunities identified through CAPA information • Manage the quality of the assigned staff’s clinical work • Coordinate efforts between Project Management, Site Management, and Study Start‑Up • Establish regular communication to include quality metrics (such as site visit report compliance, source data verification metrics, and on‑site metrics) and overall project “health” metrics (such as data query status, adherence to the scope of work, and resource status) • Conduct performance appraisals for direct reports

• Lead global clinical trial execution and operational delivery across internal and external stakeholders • Provide oversight of CROs, vendors, and clinical trial partners to ensure quality, compliance, timelines, and budget objectives are achieved • Drive risk identification, issue escalation, and mitigation planning across assigned studies • Support study start up, site feasibility, enrollment, and operational execution activities • Partner cross-functionally with Clinical Development, Regulatory, Safety, Biometrics, Supply Chain, and external vendors • Contribute to SOP development, process optimization, inspection readiness, and operational excellence initiatives • Mentor junior Clinical Operations team members as applicable