Role Description The Senior Product Manager, Upstream will shape the future product strategy for the Tablo Hemodialysis System by defining market requirements, identifying unmet clinical and customer needs, and influencing the product roadmap. This role serves as the voice of the market—ensuring clinical realities, customer insights, and market dynamics inform product development decisions. Partnering closely with Clinical Affairs, R&D, Engineering, Marketing partners, and our customers, this leader translates insights into clear requirements and strategic trade-offs that guide lifecycle planning, platform evolution, and innovation priorities. Success in this role is measured by the quality of market insight, clarity of product requirements, and the impact those inputs have on differentiated, clinically relevant, and commercially viable solutions. Essential Job Functions & Responsibilities - Market Insight & Strategy - Lead lifecycle planning for existing product lines, identifying opportunities for enhancement, refresh, or derivative extensions. - Analyze market trends, competitive dynamics, customer feedback, and clinical insights to identify unmet needs and whitespace. - Develop actionable insights that guide portfolio prioritization and long-term strategy. - Product Requirements & Roadmap Influence - Define and prioritize product requirements based on market and clinical inputs. - Translate customer and clinician needs into clear feature requirements and value drivers. - Partner with Product Management and R&D to assess trade-offs between clinical, technical, and commercial considerations. - Cross-Functional Product Leadership - Serve as a key strategic partner to Upstream Product Management, Clinical Affairs, Engineering, and R&D. - Ensure product decisions are grounded in real-world workflows, stakeholder needs, and market realities. - Support early-stage concept development, business cases, and investment decisions. - Lifecycle & Performance Feedback - Support post-launch evaluation to inform future roadmap decisions. - Ensure learnings from commercialization and customer use are incorporated into ongoing product planning. Qualifications - Bachelor’s degree - 6–8 years of experience in medical device marketing or product management, preferably capital equipment or healthcare technology - Proven experience supporting upstream product planning and influencing product roadmaps - Strong analytical and problem-solving skills with the ability to translate insight into strategy - Excellent collaboration and communication skills across technical, clinical, and commercial teams - Entrepreneurial mindset with comfort operating in ambiguity - Proficiency with Microsoft Office and CRM/marketing automation platforms (e.g., Salesforce, Marketo, Eloqua) - Willingness to travel up to 25–35% Benefits - National Salary Range (Remote): $136,000 — $183,600 USD Company Culture At Outset, we believe every person matters. Every Outsetter, every patient, every caregiver. Because we are here to create a revolution, and we believe in doing that by innovating everywhere with intelligent speed. Our team expects nothing less than our best display of strengths and skills, and we find joy in working together for a common goal. At Outset, we believe that curiosity, ingenuity and conviction in the power of technology will transform the lives of dialysis patients and providers. We are fueled by the opportunity to give people their lives back. And we believe that it begins with YOU, our future Outsetter. At Outset, we’ve designed a professional world that our employees are honored and impassioned to belong to, one that offers challenge, the ability to collaborate with great people, and opportunities to build skill and expertise in a fulfilling career. An opportunity at Outset Medical won’t just be about finding a job. Our culture revolves around the principles of moving farther, faster, together, so working here feels like a masterclass in peak performance, for individuals and teams.

• Contribute to product strategy, roadmap planning, and ongoing product evolution • Support pricing, packaging, and positioning decisions • Help identify opportunities across media and video technology ecosystems • Monitor industry trends in media technology, such as streaming, content workflows, and cloud platforms • Engage with customers to understand workflows, challenges, and priorities • Work with cross-functional teams to align on product priorities and delivery • Partner with engineering and R&D teams to deliver product features • Participate in industry events, customer sessions, or product discussions as needed

• Own the “why” and the “what.” Translate user needs and business goals into a clearly-framed problem and a crisp definition of success, and then guide the team in owning the “how.” • Collaborate with other product leaders to define the metric that matters. Set the outcome you’re driving toward, instrument it, and measure success by user behavior change over features shipped. • Work lightweight. Use story maps, one-pagers, and just-enough framing to align the team. We favor working software over comprehensive documentation; you won’t get extra credit for writing exhaustive PRDs or hand-detailing acceptance criteria if it’s not actually used by developers and designers. • Partner directly with engineers and designers. Collaborate in real time, every day. • Push for experimentation and validation. Form hypotheses, design the smallest test that produces real learning, and adapt based on evidence. • Ship true MVPs. Know the difference between a real minimum viable test and a watered-down v1. Get something in front of users quickly, then improve. • Prioritize ruthlessly. Protect the team’s capacity for high-leverage work. Say no to good in service of great, and kill work that won’t deliver value (without ego or sunk-cost thinking). • Keep the user at the center. Stay close to real users, synthesize what you learn, and make sure every bet connects back to a user reaching a career milestone. • Use AI as a tool. Lean on AI thoughtfully to move faster and sharpen your thinking, but not as a replacement for talking to users or good judgment.

• Own and articulate the vision, strategy, and roadmap for lead management and distribution, ensuring alignment with company objectives and market opportunities. • Translate business goals into product priorities, balancing long-term vision with iterative value delivery. • Drive Go-to-market decision making to ensure business goals from product releases are achieved. • Quantify and model opportunity sizes to inform investment decisions and sequencing. • Lead cross-functional planning and ensure resources are focused on the highest-impact initiatives. • Partner with leadership to define pricing, packaging, and monetization strategies for your domain. • Leverage AI to accelerate product development workflows, including research, PRD development, prototyping, analysis, and experimentation. • Maintain a deep understanding of both lead buyers and sellers, speaking regularly with customers to uncover pain points and opportunities. • Translate customer insights into actionable strategies and feature development. • Stay informed on competitor trends, compliance regulations, and technology advancements influencing the lead ecosystem. • Ensure the voice of the customer is central to product decisions and trade-offs. • Build customer feedback loops, including a customer advisory board, to continuously validate product direction. • Define and own the core business metrics for your product area, including lead volume, quality, conversion, yield, and ROI. • Use quantitative and qualitative data to identify opportunities, validate hypotheses, and measure success. • Collaborate with analytics teams to establish clear KPI tracking and visibility for leadership. • Incorporate experimentation and testing frameworks to evaluate product improvements and GTM effectiveness. • Drive high-quality, predictable delivery in partnership with engineering and design. • Lead scoping sessions and manage prioritization across multiple stakeholders and dependencies. • Ensure new capabilities are launched with clear success criteria, tracking, and operational readiness. • Partner with Product Marketing and Client Success to plan GTM launches and customer onboarding that deliver measurable business impact. • Maintain accountability for results and continuous improvement after release. • Work cross-functionally with engineering, marketing, client success, sales, and finance to achieve shared goals. • Act as the central point of contact for your product area, ensuring clear communication of priorities, progress, and outcomes. • Foster alignment and transparency across teams; proactively surface risks and trade-offs. • Represent your product domain in company-wide planning, portfolio reviews, and leadership updates. • Demonstrate full ownership from problem identification through solution delivery and adoption. • Mentor and support Associate PMs or peers in discovery, prioritization, and customer engagement. • Model urgency, accountability, and customer obsession consistent with company values. • Contribute to a culture where team members feel engaged, challenged, and recognized for delivering impact.