• Provide disease state, product, and ongoing therapy management education upon request, in consumer friendly language to the Rett community, which may include patients, caregivers, and/or other care team members. Caregiver engagement may take place before, during, and after therapy initiation, through various formats, including in-person, telephonic, and/or virtual interactions. • Determine individual needs of patients and caregivers and serve as an ongoing resource to provide appropriate education and resources accordingly, throughout the various stages of the patient journey. • Collaborates with and provides support for the entire assigned territory, which consists of multiple internal cross-functional partners (Marketing, Sales, Patient Access Team, Medical Affairs, Advocacy, and others), and may require coverage of multiple states. Supports and communicates educational opportunities with cross functional partners, as appropriate. • Possess expert knowledge and provide insights to internal stakeholders including, but not limited to, training leads, marketing partners, advocacy, medical and leadership, in an effort to develop tools and resources to address educational gaps, enhance disease state education, and therapy management strategies to patient families/caregivers. • Demonstrate deep knowledge of disease state, product, and Acadia Customer Support Programs, such as Hub-related and Patient Assistance Programs, and ambassador speaker programs, etc. • May moderate, lead and present caregiver speaker programs as needed, and attend community events within assigned territory. • Provide in-service to physician offices reactively, to educate about the Family Support Educator role, patient support resources provided to caregivers, pre and post enrollment in the program, and foster a dialogue between caregivers and healthcare providers. • Identify and execute on opportunities to provide leadership within the Family Support Educator team and with cross functional partners. • May provide formal mentorship and/or development opportunities with new Family Support Educator team members, and/or to cross functional colleagues interested in Patient Support Services. • Identify training and development opportunities related to Patient Support Services and the broader organization. • Ensures that all actions, both internally and externally, working on Acadia’s behalf are in compliance with all laws, regulations, policies and demonstrates Acadia values.

• Develop, execute and maintain high impact territory plans, including HCP and Investigator engagement plans in alignment with therapeutic area medical and scientific objectives with a focus on quality. • Support clinical development and research initiatives across development at the request of R&D. • Identify, gain access to, and develop professional customer centric based relationships with external experts in Immuno-Oncology within assigned geography. • Provide education relative to disease state, therapeutic landscape and Summit Therapeutics products across the product lifecycle to healthcare providers and researchers. • Participate, monitor, and provide insights to Summit from relevant scientific meetings in relevant geography. • Continuously maintain self-education on market issues/trends, product knowledge, and new therapeutic areas of interest as it pertains to specific business responsibilities. • Actively participate in relevant team meetings, organizational activities, and Country-driven medical affairs activities (e.g. advisory boards, masterclasses, roundtables). • Create, maintain, and collaborate in relationships with Cross-Functional partnerships to develop and execute Account plans.

• The Field Clinical Specialist is responsible for the training, support and adoption of OrganOx’s products. • Teach and train users in the correct manner to ensure our products are used safely and effectively. • Maintain the relationship with the relevant clinical transplant teams. • Home based but will require frequent travel to allocated transplantation centers (40%-60%). • Partake in the 24/7 on-call rota (including weekends and holidays) for on-site or remote support. • Promote the benefits of OrganOx’s products with customers. • Facilitate the sharing of customer experiences to support adoption of OrganOx products. • Arrange user groups to facilitate shared learning. • Track account performance, clinical progression, and supports forecasting of system usage and consumables set allocation. • Ensure customer data are maintained in the relevant database and all regulatory customer consent is collected and documented. • Support the Commercial management team in prospecting and generating new customer leads.

**Position Summary ** The Clinical Specialist will be primarily responsible for training and supporting users of our products. This includes teaching and training users in the correct manner to ensure our products are used safely and effectively - both for the preservation of organs prior to transplant, and for various clinical and non-clinical research studies. The role of Clinical Specialist will involve global travel, primarily within North America, visiting leading sites of transplantation surgery. This means the Clinical Specialist will be required to work after business hours, including nights, weekends and some very long days, which is the norm due to the unpredictable nature of organ donation and transplantation.