Kyverna Therapeutics logo
Kyverna Therapeutics

Taming Autoimmunity™

Vice President, Lifecycle Leader

Vice PresidentVice PresidentFull TimeRemoteSeniorTeam 51-200Since 2019H1B No SponsorCompany SiteLinkedIn

Location

United States

Posted

9 days ago

Salary

$300K - $340K / year

Seniority

Senior

Postgraduate Degree15 yrs expEnglish

Job Description

Vice President, Lifecycle Leader

Kyverna Therapeutics

• Serve as the executive lifecycle lead for future indications and is accountable for the integrated asset strategy across clinical development, regulatory strategy, manufacturing readiness, and commercialization planning. • Define and maintain the integrated development plan and lifecycle strategy, aligned with the Target Product Profile and long-term commercial value drivers. • Drive strategic planning for key development milestones including Phase transitions, pivotal trial strategy, regulatory interactions, and launch readiness. • Ensure program execution is aligned with corporate strategy, timelines, regulatory requirements, and budget targets. • Lead and develop the Lifecycle Leaders organization, providing strategic oversight and mentorship to lifecycle leads across Kyverna’s development portfolio. • Establish best-in-class lifecycle governance, decision frameworks, and cross-program coordination processes. • Partner with the Executive Leadership Team to ensure portfolio prioritization and investment decisions align with corporate strategy and value creation. • Standardize lifecycle strategy development, program governance, and cross-functional planning across programs. • Serve as a primary strategic advisor to executive leadership on program strategy, portfolio risk, and lifecycle opportunities. • Lead preparation and presentation of program updates, strategic options, and decision packages to governance committees and the Board. • Ensure robust risk assessment, scenario planning, and mitigation strategies are in place across the program. • Define go/no-go decision points and guide governance discussions around program investment and strategic direction. • Represent Kyverna externally with key scientific, regulatory, and industry stakeholders. • Support strategic partnerships, collaborations, and licensing discussions where appropriate. • Engage with key opinion leaders and external experts to inform program strategy. • Ensure coordinated execution across all functional areas including: • Oversee the development and execution of key program deliverables including:

Job Requirements

  • PhD, MD, PharmD, MBA or equivalent advanced degree preferred.
  • 15+ years of experience in biotechnology or pharmaceutical drug development, including significant leadership experience in clinical-stage programs.
  • Demonstrated success leading complex global development programs from early development through late-stage clinical trials and regulatory filings.
  • Experience serving as a program or lifecycle leader for a major therapeutic asset is required.
  • Experience in Neuroimmunology is strongly preferred.
  • Strong expertise in autoimmune disease, immunology, cell therapy, biologics, or related therapeutic areas strongly preferred.
  • Deep understanding of the end-to-end drug development value chain, including research, translational science, clinical development, regulatory, manufacturing, and commercialization.
  • Experience with global regulatory interactions and major submissions (IND, BLA, NDA).
  • Demonstrated leadership in cross-functional matrix organizations and enterprise governance structures.
  • Ability to interpret complex clinical and scientific data and translate insights into strategic decisions.
  • Experience leading cross-functional teams in high-growth biotechnology environments.
  • Strategic, enterprise-level thinker capable of driving portfolio-level impact.
  • Strong executive presence and ability to influence senior leadership and Board stakeholders.
  • Proven ability to lead high-performing cross-functional teams in complex, fast-moving environments.
  • Strong judgment and decision-making skills in the face of uncertainty and evolving scientific data.
  • Excellent communication and stakeholder management skills.

Benefits

  • This position is also eligible for bonus, benefits, and participation in Company’s stock plan.

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