• Prepare accurate cost estimates, budgets, and detailed take-offs based on project plans and specifications • Analyze drawings, materials, labor, and time requirements to develop competitive bids • Liaise with suppliers and subcontractors to obtain pricing and proposals • Identify risks, cost-saving opportunities, and value engineering options • Maintain and update cost databases and estimating tools • Plan, coordinate, and oversee projects from award to completion • Develop project timelines, schedules, and resource allocation plans • Manage subcontractors, suppliers, and internal teams • Track project progress, costs, and performance against budget • Ensure compliance with safety standards, regulations, and quality requirements • Communicate regularly with clients and stakeholders, providing updates and resolving issues • Handle change orders, variations, and contract administration

• The Start Up Project Manager is responsible for defining, developing and delivering the global start up project strategy by partnering with roles across GSSO, CD&O, Global Regulatory Submissions and others as required. • The SUPM will be assigned to one or more interventional studies in one or more therapy areas such as oncology, vaccines, internal medicine, rare disease or inflammation and immunology. • The SUPM will have a comprehensive knowledge of managing and coordinating study start up activities globally. • The SUPM will typically take full responsibility for medium to large size studies across all regions and countries, or for selected countries or region(s) of a global study where another SUPM is responsible for the site activations of the entire study. • The SUPM will work with country level start up roles to seek opportunities to accelerate site activations for their study. • Lead start up meetings that facilitate alignment of site selection to activation activities performed by country level start up roles with the endorsed trial optimization plan (by senior leadership). • Accountable for quality and completeness of start up timeline plans at study, country and site level within an enterprise project management (EPM) system. • Responsible for creating and overseeing the initial baseline and subsequent snapshots of timeline planning within the EPM system which build the overall targets for site activation over time in alignment with the priority of the study in the overall portfolio and overall expectation to deliver to plan with a high degree of probability. • Expertly integrate the requirements of a protocol amendment(s) to deliver site activations to plan prioritizing optimizing participant recruitment. • Responsible for the completeness and quality of site activation timeline plans for every site from investigator initiation package sent for first site in study to site activation complete for last site in study.

• Define, develop and deliver the global start up project strategy by partnering with roles across GSSO, CD&O, Global Regulatory Submissions and others as required • Take full responsibility for small to medium size studies located in a single country or region • Lead start up meetings that facilitate alignment of site selection to activation activities performed by country level start up roles with the endorsed trial optimization plan • Accountable for quality and completeness of start up timeline plans at study, country and site level within an enterprise project management (EPM) system • Co-ordinate and oversee progress of study specific or country specific tasks that need to be completed for site activations • Expertly integrate the requirements of a protocol amendment(s) to deliver site activations to plan • Act as a key point of escalations for site activation related issues raised by country level start up roles • Continually assess current and future workload to proactively anticipate, problem solve

• Identify and pursue new business opportunities, leveraging your industry network and market insight • Collaborate with executive leadership to shape service offerings, go-to-market strategies, and regional positioning • Serve as a trusted advisor to clients across sectors including real estate, insurance, legal, construction, industry, and public agencies • Lead proposal development, client presentations, and contract negotiations to secure high-value projects • Drive revenue growth through strategic account management and cross-functional collaboration • Oversee and contribute to a wide range of EH&S projects, ensuring technical excellence, regulatory compliance, and client satisfaction across all project phases • Lead multidisciplinary teams in the planning, execution, and delivery of complex environmental and health & safety initiatives • Develop and implement quality assurance/quality control (QA/QC) protocols to maintain high technical standards • Mentor junior staff and foster a culture of continuous improvement and professional development • Collaborate with clients to define project goals, manage expectations, and deliver tailored solutions • Track and report key performance indicators (KPIs) to evaluate project success and drive operational efficiency.