Arvinas is a biotechnology research company that is “propelling the future with targeted protein degradation.” As an employer, the company believes its team members “make the
Vice President, Technical Operations
Location
United States
Posted
26 days ago
Salary
0
Seniority
Mid Level
No structured requirement data.
Job Description
Vice President, Technical Operations
Arvinas
Role Description This is a senior executive role responsible for all CMC activities from preclinical to product launch and leadership of an established Technical Operations group. The role has oversight of drug substance (API) and drug product (DP) development and production for preclinical, clinical, and commercial requirements. It is responsible for development, scale-up, analytical testing of API and DP. The role has oversight of identification, on-boarding, and management of external vendors and CMO’s. The incumbent is responsible for representing Arvinas CMC function in meetings with regulatory authorities and review of CMC documentation consistent with relevant regulations and guidelines. The role is responsible for higher level integration of Technical Operations activities with key stakeholders such as discovery chemistry, quality, clinical, and regulatory groups. This role is a key member of the Executive Committee Portfolio team, Development Governance, and reports to the Chief Financial Officer. The role can be remote, hybrid, or located at our headquarters in New Haven, CT. Principal Responsibilities - Leadership of the Technical Operations group which incorporates exploratory pharmaceutics, API, DP and Analytical Development, supply chain planning, and CMC authoring. - Ensuring product supply from pre-clinical development through clinical to commercialization. - Providing strategic direction and planning of the technical development and manufacturing of clinical/commercial products with attention to quality, robust and reliable supply, cost-effectiveness and efficient scaling. - Continuing a Technical Operations approach that establishes fast-to-clinic and fast-to-commercial as primary objectives in support of the Arvinas pipeline. - Responsible for establishing and managing the relationships with contract manufacturers, to assure that commercial and clinical production needs are met cost-effectively and in compliance with all GMP regulations and regulatory standards. - Establishing partnerships with Discovery, Clinical, Quality, Regulatory and Commercial to ensure a rapid and successful progression of assets to the commercial market. - Developing and managing annual expense budgets with accurate forecasting based on strategic objectives and prudent decisions regarding expenditures. - Interfacing with senior management to reach decisions that provide best opportunity for organizational success. - Leading the compilation and review of technical sections for Module 2/3 in INDs, IMPDs, NDAs, and MAAs. - Acting as a key executive interface with FDA and EMA for quality sections in INDs, NDAs, IMPDs, and MAAs. - Building a high performing team ensuring that organizational depth is maintained for all key positions. Qualifications - A minimum of 20 years experience working within areas of medicinal chemistry, chemical development, pharmaceutical development, and/or analytical development. - At least 10 years’ experience in a small/medium biotech environment with substantial CMC area leadership responsibilities. - Expertise in small molecule synthesis and process development, pre-formulation/formulation development, and analytical development of the same is required. - Expert-level understanding of API/DP process development and scale-up. - Expert-level understanding of analytical methods and instrumentation used to characterize reactions, material properties, APIs, and drug products. - Experience with and understanding Design of Experiments (DOE), Quality by Design (QbD), Process Analytical Technology (PAT), scale up, formulation and process technologies. - Demonstrated success in advancing a molecule from drug discovery to commercialization. - Demonstrated success in drafting module 2/3 sections of INDs, IMPDs, NDAs, and MAAs. - Extensive working knowledge of GxP practices, ICH guidelines, and other regulatory practices as applied to phase-appropriate applications. - Strong leadership and management abilities. - Critical analysis and strategic thought embedded within exceptional decision-making abilities. - Excellent communication, problem-solving and organizational skills applicable in a cross-functional team environment. - Extensive knowledge of scientific literature and of emerging research areas of pharmaceutical science. Requirements - Arvinas will not be providing VISA sponsorship for this position. You must have the ability to work without a need for a current or future VISA sponsorship. - The duties of this role are generally conducted in a combination of office, lab and home office environments. - Employees must be able, with or without an accommodation to lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving, analysis and dialogue; collaborate with others; maintain general availability during standard business hours. Education - Ph.D. in organic/medicinal chemistry or pharmaceutics. A combination of relevant education, demonstrated subject matter expertise, and applicable job experience may be considered in lieu of the degree. Benefits - Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. - Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. Company Description Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins.
Related Guides
Related Categories
Related Job Pages
More Operations Jobs
Lead Operations Manager
The Treetop ABAAutism therapy provider now servicing Georgia, Arizona, New Mexico, Colorado & Oklahoma w/ home and clinic services.
• Directly manage, coach, and mentor Operations Managers who coordinate care between patients and technicians across multiple regions and states • Set clear expectations, drive accountability, and support professional growth • Build strong, engaged teams aligned around client outcomes • Establish clear expectations and standards, and ensure proper communications for: Technician engagement and stability, Client retention and satisfaction, Fulfillment of prescribed therapy, Service continuity and recovery from disruption • Ensure consistent execution of The Treetop’s client lifecycle procedures across regions • Monitor service fulfillment, disruption resolution, scheduled-to-actual performance, documentation quality, and retention of both clients and technicians • Identify trends, risks, and bottlenecks; implement corrective action plans • Monitor high-risk operational scenarios (extended service disruptions, repeated cancellations, pending discharges) • Ensure Operations Managers maintain strong, proactive relationships with families once services are active • Oversee escalation management for high-risk or complex client situations, including service disruptions and pending discharges • Reinforce a family-centered approach that balances operational efficiency with compassionate, responsive care • Ensure Operations Managers maintain strong, proactive relationships with technicians once they are assigned to a client • Create workflows to document and track technician satisfaction and performance • Build processes to and work with scheduling to ensure adequate hours for technicians • Collaborate with Clinical, Scheduling, Recruiting, and Executive leaders to ensure adherence to payer requirements, internal policies, and SOPs across all operational teams • Help design and refine compensation and incentive plans for Operations Managers that are aligned with client outcomes and service fulfillment • Support growth, standardization, and continuous improvement across regions, and drive continuous improvement initiatives using data in Salesforce
• Build and maintain recurring reports across key operational and financial metrics • Support portfolio-level and market-level views for internal stakeholders • Field data requests from operations teams and translate business questions into structured analysis and clear findings • Help scope what is answerable with available data and communicate results to non-technical audiences • Maintain and develop data models that support external client reporting needs • Collaborate with client-facing teams to translate business requirements into technical solutions • Participate in client meetings and recurring syncs to stay aligned on priorities and build context around how partners interact with data
Expert Team Associate
Staples Inc.Staples is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, age, national origin, protected veteran status, disability, or any other basis protected by federal, state, or local law.
Role Description As a SMB Expert Representative, you will play a crucial role in engaging customers, understanding their needs and effectively communicating the value of our products. You will interact with customers through email, phone, and Microsoft Teams video meetings. Your ability to demonstrate professionalism, build rapport, overcome objections, and close deals through written and verbal communication will be key to driving customer loyalty and revenue growth. An important aspect of this role is to be customer centric and growth-oriented, aiming to help our customers grow their business with Staples. - Engage customers through email, phone, and Microsoft Teams video meetings, responding promptly and professionally via Staples systems. - Understand customer needs, provide solutions, and promote Staples products with confidence and expertise. - Maintain accurate Salesforce records to manage workflow and sales pipeline effectively. - Conduct account research, analyze sales trends, and prepare for customer interactions to drive growth. - Navigate contract types and account setups, manage pricing conversations, and participate in ongoing training. - Leverage product knowledge and selling skills to build trust and convert conversations into sales leads. - Qualify, manage, and close sales leads, capturing key information and ensuring smooth handoff to appropriate teams. - Collaborate with Category Sales Specialists and Customer Service to resolve issues and ensure customer satisfaction. - Deliver against performance targets and service KPIs, including revenue, opportunity generation, close rate, and customer satisfaction. Qualifications - Act as a dedicated expert for Staples’ small to mid-sized business accounts. - Drive growth through proactive lead generation and consultative, solution-based support. - Strengthen customer loyalty with personalized engagement and effective issue resolution. - Enhance satisfaction and conversion by building trust and confidence in the Staples partnership. - Thrive in a dynamic sales environment, confidently promoting product solutions and influencing customer decisions. - Strong organization and time management skills; ability to juggle multiple priorities and deliver timely results. - Effective communication skills, both written and verbal, with a positive and professional demeanor. - Ability to navigate multiple software applications simultaneously. Requirements - Minimum 1+ years’ experience in a customer-focused, customer service, or sales role. - Experience using a computer, Excel, and Outlook. - Proactive nature and exceptional typing ability (60 wpm). - Previous experience using Salesforce or a comparable sales tool. Benefits - Inclusive culture with associate-led Business Resource Groups. - 112 Hours of PTO and Holiday Schedule (7 observed paid holidays + 1 floating holiday). - Online and Retail Discounts, Company Match 401(k), Physical and Mental Health Wellness programs, and more!
• Apoiar e/ou estruturar a gestão e otimização do funil de vendas (pipeline, forecast e conversões); • Monitorar e analisar indicadores de performance comercial (KPIs), gerando insights acionáveis; • Desenvolver e manter dashboards e relatórios gerenciais; • Garantir a qualidade, organização e governança dos dados no CRM; • Suportar o time comercial com análises para tomada de decisão; • Contribuir com o planejamento de metas, performance e regras de comissionamento/remuneração variável; • Identificar oportunidades de melhoria contínua em processos, ferramentas e eficiência operacional; • Atuar em parceria com áreas como Marketing, Produto, Crédito e Tecnologia.
