• Lead and develop a distributed team of IT professionals across the US and Europe, supporting day-to-day operations and team growth • Support IT operations across a globally distributed workforce • Own core IT service operations, including user provisioning, access management, SaaS administration, and endpoint lifecycle management • Manage identity and access systems (e.g., Okta), ensuring secure, scalable, and efficient access workflows • Drive automation of IT processes such as onboarding, offboarding, and access changes using tools like Tines or similar platforms • Administer and optimize SaaS platforms including Google Workspace, Slack, Zoom, GitHub Enterprise, and others • Track SaaS license usage, monitor spend, and identify opportunities for cost optimisation and tooling improvements • Partner with Security, People, and business leaders to ensure compliance, access governance, and strong employee experience • Support the transition of IT operations from an external provider to an in-house team, improving service quality and operational visibility • Define and track key IT metrics (e.g., provisioning speed, service quality, system usage) to drive continuous improvement

• Manage eviction-related processes and ensure alignment between Owner and Darwin systems • Maintain and provide routine updates to the shared Evictions Tracker • Partner with the internal Evictions Team • Meet with external attorneys at least monthly to ensure compliance with local laws and new statutes • Support ISP opt-out processes related to evictions • Train and audit local PM teams to establish rules of engagement on daily compliance issues • Establish a compliance and evictions SOP and train PM staff on SOP as well as fair housing regulations • Support regulatory compliance initiatives • Conduct ad-hoc and annual reviews of state-level landlord-tenant laws • Facilitate updates to lease addenda and operational workflows based on regulatory changes • Oversee real estate license tracking and management • Engage in further advancing licensing for our leadership team • Research, evaluate and establish a professional development track for PM staff in the Real Estate field • Coordinate legal case support between stakeholders • Collect, organize, and disseminate case-related information between Darwin and the Owner • Evaluate risk factors and make recommendations to both Darwin and Client to avoid litigation and possible liability • Maintain visibility into ongoing legal matters • Provide routine updates to the Monday board • Facilitate follow-ups across Darwin, Owner, and Legal teams • Foster and maintain relationships with third-party legal advisors • Provide high-level administrative support to leadership • Coordinate internal events and logistics • Support financial operations • Regularly assess and compare third-party collection agencies by conducting pilot programs to evaluate performance across collection volume, recovery timing, and level of operational support • Collaborate with third-party partners, internal stakeholders, and clients to deliver comprehensive, data-driven insights that inform vendor selection and ensure effective use of spend • Maintain data accuracy across platforms • Perform unit-level updates to reconcile data between Owner and Darwin systems • Support lease and pricing configuration updates • Manage lease fee setting updates (as permitted by system access/role)

Role Description This is a senior executive role responsible for all CMC activities from preclinical to product launch and leadership of an established Technical Operations group. The role has oversight of drug substance (API) and drug product (DP) development and production for preclinical, clinical, and commercial requirements. It is responsible for development, scale-up, analytical testing of API and DP. The role has oversight of identification, on-boarding, and management of external vendors and CMO’s. The incumbent is responsible for representing Arvinas CMC function in meetings with regulatory authorities and review of CMC documentation consistent with relevant regulations and guidelines. The role is responsible for higher level integration of Technical Operations activities with key stakeholders such as discovery chemistry, quality, clinical, and regulatory groups. This role is a key member of the Executive Committee Portfolio team, Development Governance, and reports to the Chief Financial Officer. The role can be remote, hybrid, or located at our headquarters in New Haven, CT. Principal Responsibilities - Leadership of the Technical Operations group which incorporates exploratory pharmaceutics, API, DP and Analytical Development, supply chain planning, and CMC authoring. - Ensuring product supply from pre-clinical development through clinical to commercialization. - Providing strategic direction and planning of the technical development and manufacturing of clinical/commercial products with attention to quality, robust and reliable supply, cost-effectiveness and efficient scaling. - Continuing a Technical Operations approach that establishes fast-to-clinic and fast-to-commercial as primary objectives in support of the Arvinas pipeline. - Responsible for establishing and managing the relationships with contract manufacturers, to assure that commercial and clinical production needs are met cost-effectively and in compliance with all GMP regulations and regulatory standards. - Establishing partnerships with Discovery, Clinical, Quality, Regulatory and Commercial to ensure a rapid and successful progression of assets to the commercial market. - Developing and managing annual expense budgets with accurate forecasting based on strategic objectives and prudent decisions regarding expenditures. - Interfacing with senior management to reach decisions that provide best opportunity for organizational success. - Leading the compilation and review of technical sections for Module 2/3 in INDs, IMPDs, NDAs, and MAAs. - Acting as a key executive interface with FDA and EMA for quality sections in INDs, NDAs, IMPDs, and MAAs. - Building a high performing team ensuring that organizational depth is maintained for all key positions. Qualifications - A minimum of 20 years experience working within areas of medicinal chemistry, chemical development, pharmaceutical development, and/or analytical development. - At least 10 years’ experience in a small/medium biotech environment with substantial CMC area leadership responsibilities. - Expertise in small molecule synthesis and process development, pre-formulation/formulation development, and analytical development of the same is required. - Expert-level understanding of API/DP process development and scale-up. - Expert-level understanding of analytical methods and instrumentation used to characterize reactions, material properties, APIs, and drug products. - Experience with and understanding Design of Experiments (DOE), Quality by Design (QbD), Process Analytical Technology (PAT), scale up, formulation and process technologies. - Demonstrated success in advancing a molecule from drug discovery to commercialization. - Demonstrated success in drafting module 2/3 sections of INDs, IMPDs, NDAs, and MAAs. - Extensive working knowledge of GxP practices, ICH guidelines, and other regulatory practices as applied to phase-appropriate applications. - Strong leadership and management abilities. - Critical analysis and strategic thought embedded within exceptional decision-making abilities. - Excellent communication, problem-solving and organizational skills applicable in a cross-functional team environment. - Extensive knowledge of scientific literature and of emerging research areas of pharmaceutical science. Requirements - Arvinas will not be providing VISA sponsorship for this position. You must have the ability to work without a need for a current or future VISA sponsorship. - The duties of this role are generally conducted in a combination of office, lab and home office environments. - Employees must be able, with or without an accommodation to lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving, analysis and dialogue; collaborate with others; maintain general availability during standard business hours. Education - Ph.D. in organic/medicinal chemistry or pharmaceutics. A combination of relevant education, demonstrated subject matter expertise, and applicable job experience may be considered in lieu of the degree. Benefits - Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. - Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. Company Description Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins.

• Directly manage, coach, and mentor Operations Managers who coordinate care between patients and technicians across multiple regions and states • Set clear expectations, drive accountability, and support professional growth • Build strong, engaged teams aligned around client outcomes • Establish clear expectations and standards, and ensure proper communications for: Technician engagement and stability, Client retention and satisfaction, Fulfillment of prescribed therapy, Service continuity and recovery from disruption • Ensure consistent execution of The Treetop’s client lifecycle procedures across regions • Monitor service fulfillment, disruption resolution, scheduled-to-actual performance, documentation quality, and retention of both clients and technicians • Identify trends, risks, and bottlenecks; implement corrective action plans • Monitor high-risk operational scenarios (extended service disruptions, repeated cancellations, pending discharges) • Ensure Operations Managers maintain strong, proactive relationships with families once services are active • Oversee escalation management for high-risk or complex client situations, including service disruptions and pending discharges • Reinforce a family-centered approach that balances operational efficiency with compassionate, responsive care • Ensure Operations Managers maintain strong, proactive relationships with technicians once they are assigned to a client • Create workflows to document and track technician satisfaction and performance • Build processes to and work with scheduling to ensure adequate hours for technicians • Collaborate with Clinical, Scheduling, Recruiting, and Executive leaders to ensure adherence to payer requirements, internal policies, and SOPs across all operational teams • Help design and refine compensation and incentive plans for Operations Managers that are aligned with client outcomes and service fulfillment • Support growth, standardization, and continuous improvement across regions, and drive continuous improvement initiatives using data in Salesforce