Role Description The Senior Regulatory Affairs Associate will join a team of Regulatory Affairs professionals working together to ensure compliance with regulatory requirements. This role supports the review of regulatory and clinical documents and submissions, participation on internal and external projects/initiatives, and provision of regulatory support in key areas such as 21 CFR Part 11 compliance. This team member will work closely with others in the NMDP organization and members of our global cell collection network; support our clinical research partner, the CIBMTR in sponsored IND and IDE studies; collaborate with external global cell and gene therapy industry partners in developing novel life-saving cell and gene therapies; and communicate and support reporting activities with external regulatory agencies. Accountabilities - Identifies, assesses, and executes regulatory process improvements, initiatives and projects independently. - Represents NMDP Regulatory Team on interdepartmental projects and to external partners and collaborators. - Assists with regulatory oversight and submissions for trials where NMDP is the Sponsor of an IND or international equivalent. - Supports clinical trials, protocols and/or INDs under NMDP Master Protocol, using the Platform design. - Serves as primary regulatory expert for 21 CFR Part 11 for the Regulatory Team and on interdepartmental projects. - Performs promotional and other types of marketing material reviews for regulatory compliance. - Reviews, identifies and reports incidents, complaints, and Adverse Events to FDA, HRSA, WMDA and other agencies within appropriate timeframes. - Reviews and approves regulatory and clinical documents (e.g. protocols, amendments, Informed Consents, SOPs) for adequacy and compliance. - Identifies necessary content for submissions and studies; reviews and approves regulatory submissions. - Reviews and presents analysis of data trends with recommendations to mitigate risk or address compliance issues to internal stakeholders. - Understands and effectively communicates content for relevant US FDA regulations/guidance (e.g. 21 CFR 1271, 21 CFR 211, 21 CFR 312, etc.) - Provides excellent and responsive customer service to internal colleagues and external partners. Qualifications - Ability to utilize project planning skills to initiate, plan, and execute regulatory projects independently. - Review, collate, analyze, and summarize scientific and technical data and regulatory guidance. - Leverage understanding of the product lifecycle and apply it to NMDP products and clients. - Utilize Microsoft Word, Excel, PowerPoint, Project, Outlook and navigate data and record management systems. - Apply new technology-enabled ways of working (including technology automation and AI-assisted tools) to support document preparation, review workflows, and information organization. - Effectively communicate via written and verbal communication, tailoring communications to internal and external audiences. - Organize and prioritize multiple deliverables with competing deadlines. - Work independently and as part of a team. - Collaborate with regulatory peers, cross-functional team members, and regulatory agency partners by building strong and effective working relationships. Requirements - B.S. degree or higher in scientific field—typical majors include biochemistry, biological sciences, chemistry, pharmacy, pharmacology, toxicology, medicine, and clinical laboratory science. - 3-5 years previous regulatory experience in the device, biologic or pharmaceutical industry. Preferred Qualifications - Previous US and/or OUS experience in biologics or cell & gene therapies. - Previous regulatory experience in a Clinical Research Organization (CRO) setting. - Exposure to submissions throughout the drug/product lifecycle. - Exposure to process automation and/or AI-assisted tools used in regulated environments (e.g., document management, workflow tools, data extraction or summarization tools). - Progress towards Regulatory Affairs Certification. Benefits - Medical, dental, vision, life and disability benefits. - Accident/critical illness/hospital benefits. - Well-being, legal, identity theft and pet benefits. - Retirement plans. - Paid time off/holidays. - Leave and incentive plans for eligible employees.

• Performing field monitoring of erosion and sediment (E&S) controls on various types of construction Projects. • Reviewing and understanding specifications, permits, and permit conditions as well as E&S control and stormwater plans. • Preparing and reviewing periodic monitoring reports based upon field observations. • Assisting with the preparation of environmental reports, permit applications, and closeout requests.

Role Description The Payroll Systems Compliance Specialist supports the accuracy, compliance, and efficiency of Canadian and U.S. payroll systems. This role serves as a key resource for payroll system functionality and regulatory compliance, ensuring system configurations align with legislative requirements. The specialist will also support system testing, issue resolution, and continuous improvement initiatives. What You Will Do: - Serve as a subject matter expert for payroll system configuration, calculations, and overall functionality for Canadian and US payrolls. - Support compliance with all applicable federal, provincial/state, and local payroll tax laws and regulations for Canada and the US. - Monitor legislative changes and coordinate updates to system configurations and processes to ensure ongoing compliance. - Maintain a strong understanding of the end-to-end payroll processes for the Canadian and US payrolls, including data input, calculations, deductions, and reporting. - Provide payroll processing support for Canadian and US payrolls during absences or high-volume periods. - Gather information, investigate and resolve payroll system issues in collaboration with the HRIS team and payroll operations. - Validate payroll data integrity and accuracy with regards to the incoming and outgoing data integrations. - Plan, execute, and document testing for all payroll system updates, patches, and integrations to ensure accuracy and minimize risk. - Collaborate with the payroll team to identify system inefficiencies, and recommend improvements to enhance payroll operations and compliance. - Participate in the implementation of new system modules, enhancements, and process changes. - Develop and maintain documentation of payroll system configurations, processes, and compliance procedures. - Assist in training and supporting payroll team members on system functionalities and compliance-related updates. Qualifications - Post-secondary education or equivalent Human Resources/Payroll experience. - Certified Payroll Compliance Practitioner (PCP), or Payroll Leadership Professional (PLP). - Proven experience in payroll operations, with a strong emphasis on system administration and compliance for both Canadian and US payrolls. - Knowledge of Canadian and US federal, provincial/state, and local payroll regulations and tax laws. - Demonstrated ability to understand and interpret complex payroll calculations and system logic. - Experience with payroll system testing methods and documentation. - Strong analytical skills with an ability to identify issues, analyze data, and propose effective solutions. - Excellent communication skills, with the ability to explain technical concepts to non-technical stakeholders and collaborate effectively with team members. - High level of attention to detail and accuracy. - Proficiency in payroll software and Microsoft Office Suite. Benefits - Extended Healthcare Plan (Medical, Disability, Dental & Vision). - RPP - Group RRSP. - Group Life - AD&D - Critical Illness Insurance. - Paid Time Off Benefits. - Training & Development. - Employee Discounts. - Employee Assistance Program - Counseling.

Role Description As a Compliance Advisor, you’ll support the organization’s compliance program by executing risk‑based compliance testing. You’ll partner with compliance and business stakeholders and other risk functions to assess compliance processes and controls, identify gaps, and support effective remediation. - Conduct second‑line, risk‑based compliance testing of policies, procedures, processes, and controls using established testing standards and methodologies. - Review and evaluate documentation, data, and other evidence; conduct interviews and walkthroughs to assess control design and effectiveness. - Document testing results, including observations, root cause analysis, and risk impact, and draft clear, well‑supported testing reports. - Partner with compliance, business and risk stakeholders to discuss results, validate observations, and support development of corrective action plans. - Track remediation activities and perform follow‑up testing to assess whether corrective actions are complete and sustainable. - Apply regulatory requirements, internal policies, and risk assessment results to inform testing scope and conclusions. - Collaborate with other compliance, risk, and audit teams to promote alignment, consistency, and efficiency across testing activities. - Identify opportunities to improve testing approaches, templates, reporting clarity, and overall program effectiveness. - Leverage data, technology, and automation to improve testing efficiency, consistency, and insight. Qualifications - Bachelor’s degree or equivalent professional experience. - 6+ years of experience in compliance, risk management, audit, or related testing/monitoring roles in a regulated environment. - Strong analytical and critical‑thinking skills, with the ability to assess complex processes and exercise sound judgment. - Clear and effective written and verbal communication skills, with experience documenting results and engaging stakeholders. - Ability to work independently, manage multiple testing activities, and meet deadlines. - Collaborative mindset with the ability to build trusted relationships and provide credible challenge. Skills That Will Help You Stand Out - Prior experience performing compliance testing or monitoring activities from planning through reporting and remediation follow‑up within financial services or asset management space. - Familiarity with compliance control frameworks, issue management, and remediation practices. - Experience working across the three lines of defense. Salary Range Information Salary ranges below reflect targeted base salaries. Non-sales positions have the opportunity to participate in a bonus program. Sales positions are eligible for sales incentives, and in some instances a bonus plan, whereby total compensation may far exceed base salary depending on individual performance. Actual compensation for all roles will be based upon geographic location, work experience, education, licensure requirements and/or skill level and will be finalized at the time of offer. - Salary Range (Non-Exempt expressed as hourly; Exempt expressed as yearly): $104400 - $163000 / year - Grand Island, NE / Wichita, KS: $104,400 - $123,000 / year - Des Moines, IA / Tampa, FL: $110,200 - $130,000 / year - Charlotte, NC / Dallas, TX: $116,000 - $136,000/ year - Chicago, IL / Denver, CO / Minneapolis, MN: $127,600 - $150,000 / year - Los Angeles, CA / New York City, NY: $139,200 - $163,000 / year Time Off Program Flexible Time Off (FTO) is provided to salaried (exempt) employees and provides the opportunity to take time away from the office with pay for vacation, personal or short-term illness. Employees don’t accrue a bank of time off under FTO and there is no set number of days provided. Work Authorization/Sponsorship At this time, we're not considering applicants that need any type of immigration sponsorship (additional work authorization or permanent work authorization) now or in the future to work in the United States. This includes, but IS NOT LIMITED TO: F1-OPT, F1-CPT, H-1B, TN, L-1, J-1, etc. Investment Code of Ethics For Principal Asset Management positions, you’ll need to follow an Investment Code of Ethics related to personal and business conduct as well as personal trading activities for you and members of your household. These same requirements may also apply to other positions across the organization. Company Description At Principal, we value connecting on both a personal and professional level. Together, we’re imagining a more purpose-led future for financial services – and that starts with you. Our success depends on the unique experiences, backgrounds, and talents of our employees. And we support our employees the same way we support our customers: with comprehensive, competitive benefit offerings crafted to protect their physical, financial, and social well-being. Principal is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status. Posting Window We will accept applications for 3 full days following the Original Posting Date, after which the posting may remain open or be removed based upon applications received. If we choose to post the job again, we will accept additional applications for at least 1 full day following the Most Recently Posted Date. Please submit applications in a timely manner as there is no guarantee the posting will be available beyond the applicable deadline. Original Posting Date: 5/1/2026 Most Recently Posted Date: 5/4/2026 LinkedIn Remote Hashtag: #LI-Remote