Pharmacovigilance Signal Detection Lead Summary The Pharmacovigilance Signal Detection Lead is a senior expert responsible for leading and executing signal detection and evaluation activities across assigned client portfolios. The role combines scientific and epidemiological expertise with operational oversight of signal management workflows, ensuring that emerging safety signals are identified, assessed, prioritized, and communicated in compliance with applicable regulatory requirements (EMA GVP Module IX, ICH E2E, FDA) and client-specific procedures. The Signal Management Lead serves as the subject matter expert for signal-related activities and collaborates closely with medical reviewers, project leads, and client stakeholders. Essential Functions - Lead the design, execution, and oversight of signal detection activities, including quantitative analyses (PRR, ROR, EBGM) applied to spontaneous reporting databases (FAERS, EudraVigilance, VigiBase). - Conduct qualitative signal evaluation integrating data from spontaneous reports, clinical trials, post-authorization safety studies, scientific literature, social media monitoring, as applicable - Prepare and review signal detection reports, signal evaluation reports, and signal management plans per client SOPs and regulatory expectations. - Ensure signal management activities are completed and reported within regulatory timelines to the appropriate entities (EMA, FDA, UK MHRA). - Oversees systematic medical literature searches (Embase, PubMed) and supervise triage and assessment of results for signal-relevant publications and ICSRs. - Collaborate with the aggregate reporting team on signal-related sections of PSURs/PBRERs and DSURs. - Contribute to Risk Management Plans (RMPs) and REMS as required. - Lead, supervise, and mentor PV Specialists and Sr. PV Specialists assigned to signal detection activities - Develop and review SOPs and Work Instructions related to signal management in collaboration with the PV Quality Manager and the PV Medical Writing Manager - Ensure inspection and audit readiness and actively support QA activities including CAPA follow-up. - Interact with the PV Physician and QPPV for scientific exchange pertaining to signal assessment and benefit-risk implications. - Comply with all applicable guidelines, policies, legal, regulatory, and compliance requirements. Education: Advanced degree in pharmacy (PharmD preferred), medicine, life sciences, or epidemiology. A postgraduate qualification in pharmacoepidemiology or drug safety is an advantage. Experience: Minimum 4 years of PV experience, with at least 2 years focused on signal detection or pharmacoepidemiology at a PV vendor, CRO, or pharmaceutical company. Hands-on experience with signal detection methods and regulatory safety databases (FAERS, EudraVigilance, VigiBase) required. Computer Skills: Safety databases (like Oracle Argus Safety, ArisG LifeSphere, Veeva Safety, AB Cube SafetyEasy), signal detection tools, literature databases (Embase,PubMed), Microsoft Office Suite. Familiarity with statistical tools is an advantage. WORK ENVIRONMENT Remote: Romania / Poland or Portugal The company has reviewed this job description to ensure that essential functions and basic duties have been included. It is intended to provide guidelines for job expectations and the employee's ability to perform the position described. It is not intended to be construed as an exhaustive list of all functions, responsibilities, skills, and abilities. Additional functions and requirements may be assigned by supervisors as deemed appropriate. This document does not represent a contract of employment, and the company reserves the right to change this job description and/or assign tasks for the employee to perform, as the company may deem appropriate. To apply for this role: Step 1: Proceed to follow the form instructions Step 2: Our HR team will review your application with feedback Step 3: If successful, HR will arrange your Introductory call Step 4: A potential online language assessment Step 5: 1st formal interview Step 6: 2nd formal interview Step 7: Offer NB* To be fully informed, the Job Description will be provided at Step 3 along with further information so that all aspects of the role are covered as much as possible. Disclaimer By attaching your Curriculum Vitae (CV), resume, and/or completing an online application, you are consenting to the collection, processing, use, transfer (including but not limited to other countries/jurisdictions), storage, and disclosure of your personal data as described in the Med Communications, Inc. Privacy Policy. Please read this policy carefully for more information on your rights regarding personal data protection. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, disability, genetic information, or veteran status. Recruitment Agency Notice: Thank you for your interest in working with Med Communications. We kindly ask that recruitment agencies avoid sending unsolicited CVs, as our in-house team manages all hiring processes. Please be aware that any unsolicited CVs or candidate profiles received without prior engagement or agreement with our recruitment team will be considered free and carry no obligation on the part of Med Communications. We thank you for your compliance with our policy. Should collaboration opportunities arise, we will reach out to preferred partners proactively. Your understanding and cooperation are appreciated.

Pharmacovigilance Lead Signal Detection Summary  The Pharmacovigilance Lead Signal Detection is a senior expert responsible for leading and executing signal detection and evaluation activities across assigned client portfolios. The role combines scientific and epidemiological expertise with operational oversight of signal management workflows, ensuring that emerging safety signals are identified, assessed, prioritized, and communicated in compliance with applicable regulatory requirements (EMA GVP Module IX, ICH E2E, FDA) and client-specific procedures. The Signal Management Lead serves as the subject matter expert for signal-related activities and collaborates closely with medical reviewers, project leads, and client stakeholders.  Essential Functions - Lead the design, execution, and oversight of signal detection activities, including quantitative analyses (PRR, ROR, EBGM) applied to spontaneous reporting databases (FAERS, EudraVigilance, VigiBase). - Conduct qualitative signal evaluation integrating data from spontaneous reports, clinical trials, post-authorization safety studies, scientific literature, social media monitoring, as applicable - Prepare and review signal detection reports, signal evaluation reports, and signal management plans per client SOPs and regulatory expectations. - Ensure signal management activities are completed and reported within regulatory timelines to the appropriate entities (EMA, FDA, UK MHRA). - Oversees systematic medical literature searches (Embase, PubMed) and supervise triage and assessment of results for signal-relevant publications and ICSRs. - Collaborate with the aggregate reporting team on signal-related sections of PSURs/PBRERs and DSURs. - Contribute to Risk Management Plans (RMPs) and REMS as required. - Lead, supervise, and mentor PV Specialists and Sr. PV Specialists assigned to signal detection activities - Develop and review SOPs and Work Instructions related to signal management in collaboration with the PV Quality Manager and the PV Medical Writing Manager - Ensure inspection and audit readiness and actively support QA activities including CAPA follow-up. - Interact with the PV Physician and QPPV for scientific exchange pertaining to signal assessment and benefit-risk implications. - Comply with all applicable guidelines, policies, legal, regulatory, and compliance requirements. Education:  Advanced degree in pharmacy (PharmD preferred), medicine, life sciences, or epidemiology. A postgraduate qualification in pharmacoepidemiology or drug safety is an advantage.  Experience:  Minimum 4 years of PV experience, with at least 2 years focused on signal detection or pharmacoepidemiology at a PV vendor, CRO, or pharmaceutical company. Hands-on experience with signal detection methods and regulatory safety databases (FAERS, EudraVigilance, VigiBase) required.  Computer Skills:  Safety databases (like Oracle Argus Safety, ArisG LifeSphere, Veeva Safety, AB Cube SafetyEasy), signal detection tools, literature databases (Embase,PubMed), Microsoft Office Suite. Familiarity with statistical tools is an advantage. WORK ENVIRONMENT Remote: Romania / Poland or Portugal The company has reviewed this job description to ensure that essential functions and basic duties have been included. It is intended to provide guidelines for job expectations and the employee's ability to perform the position described. It is not intended to be construed as an exhaustive list of all functions, responsibilities, skills, and abilities. Additional functions and requirements may be assigned by supervisors as deemed appropriate. This document does not represent a contract of employment, and the company reserves the right to change this job description and/or assign tasks for the employee to perform, as the company may deem appropriate. To apply for this role: Step 1: Proceed to follow the form instructions Step 2: Our HR team will review your application with feedback Step 3: If successful, HR will arrange your Introductory call Step 4: A potential online language assessment Step 5: 1st formal interview Step 6: 2nd formal interview Step 7: Offer NB* To be fully informed, the Job Description will be provided at Step 3 along with further information so that all aspects of the role are covered as much as possible. Disclaimer By attaching your Curriculum Vitae (CV), resume, and/or completing an online application, you are consenting to the collection, processing, use, transfer (including but not limited to other countries/jurisdictions), storage, and disclosure of your personal data as described in the Med Communications, Inc. Privacy Policy. Please read this policy carefully for more information on your rights regarding personal data protection. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, disability, genetic information, or veteran status. Recruitment Agency Notice: Thank you for your interest in working with Med Communications. We kindly ask that recruitment agencies avoid sending unsolicited CVs, as our in-house team manages all hiring processes. Please be aware that any unsolicited CVs or candidate profiles received without prior engagement or agreement with our recruitment team will be considered free and carry no obligation on the part of Med Communications. We thank you for your compliance with our policy. Should collaboration opportunities arise, we will reach out to preferred partners proactively. Your understanding and cooperation are appreciated.

• You apply VIDA’s spatial analysis tools and prepare our software for real-life projects, energy access planning • You improve, automate, and extend our workflows with Python and SQL scripting. • You explore, pre-process, and integrate new datasets and map layers into the VIDA software. • You explore and implement new spatial data analysis methods, for example, by using Machine Learning methods and sector-specific modelling frameworks. • You ensure clear documentation, reporting, and communication across all project phases. • You ensure project outputs (VIDA software products and reports) meet technical quality standards and are accessible to end-users. • You interact with our international project partners and clients, and prepare/present your work in reports and presentations. • You facilitate workshops, trainings, and meetings to ensure alignment and adoption of project outcomes. • You contribute GIS-based analytical work specifically for energy access projects in developing countries, translating geospatial insights into practical planning recommendations.

American Straight A Academy (ASAA) Part-Time Remote High School Science Teachers Wanted Teach globally. Work flexibly. Join a fast-growing international online school delivering American high school education to students worldwide. Open Subjects (High School Level) • Environmental Science • Chemistry • Biology Class Schedule (Pacific Time) • Option 1: Sun / Tue / Thu 6:00 PM to 9:00 PM or 10:00 PM to 12:30 AM • Option 2: Mon / Wed 6:00 PM to 9:00 PM or 10:00 PM to 12:30 AM Flexible Commitment No upper limit. Teaching hours depend on teacher availability within the schedule options above. Role Overview • Teach engaging 1-on-1 or small group (2–6 students) online classes • Deliver lessons using structured teaching materials (textbooks, slides, etc.) • Track student progress and submit timely post-class feedback Requirements • Bachelor’s degree or above (Master’s preferred) • At least 1 year of teaching experience in a related subject area (high school experience preferred) • Strong communication skills and a professional teaching attitude • Reliable, punctual, and consistent in teaching delivery Contact Emily.liu@asaaeducation.com This is a remote position.