Global Study Manager - Cardiovascular ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development We are currently seeking a Global Clinical Trial Manager to join our diverse and dynamic team. As a Global CTM at ICON, you will play a pivotal role in supporting the coordination and management of global studies in Cardiovascular, contributing to the design, analysis, and advancement of innovative treatments and therapies. Must be able to start by 1st July 2026 or sooner. What you will be doing - Assisting project managers in the planning, execution, and monitoring of clinical trials. - Coordinating study activities, including site selection, patient recruitment, and data collection. - Supporting the development of study protocols, case report forms, and other study-related documents. - Participating in data analysis and interpretation to support decision-making and regulatory submissions. - Collaborating with cross-functional teams to ensure project milestones are met and deliverables are achieved. - Vendor management, selecting vendors, managing and leading the performance and delivery of vendors as well as managing vendor budgets. Your profile - Bachelor's degree in a scientific or related field; advanced degree preferred. - Minimum of 2 years of experience in clinical research or project management. - you MUST have the following experience: Global Vendor management experience from selection, managing and managing vendor budgets - Global experience is a Must - Must have current experience working within Pharma or CRO experience - Strong organizational and multitasking skills. - Excellent communication and interpersonal skills. - Ability to work effectively in a fast-paced and team-oriented environment. What ICON can offer you: Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family. Our benefits examples include: - Various annual leave entitlements - A range of health insurance offerings to suit you and your family’s needs. - Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead. - Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being. - Life assurance - Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others. Visit our careers site to read more about the benefits ICON offers. At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here. Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles. Are you a current ICON Employee? Please click here to apply

What you’ll be doing: o Focus on business objectives and understand the importance of achieving internal and external service levels to eliminate financial penalties, improve customer satisfaction, and reduce complaints. o With the support of Capita policies and local initiatives, you will be responsible for managing human resources and making key decisions. This includes developing your direct reports through personal accountability and effective performance management. You will achieve this by setting objectives, conducting 1-2-1 meetings and appraisals, overseeing recruitment and selection, providing coaching, and managing absences and disciplinary actions. o Proactively motivate staff, develop a team ethos, and minimize staff absence and attrition. o Ensure all defined processes and reporting requirements are followed by team members. o Use management information to understand quality issues, KPIs, and trends, and identify and deliver remedial actions and improvement opportunities. o Collaborate with the Quality Learning Support team (QLS), Regional Clinical Team, and Clinical Governance Team to monitor quality and coach Functional Specialists. o Ensure coaching targets are achieved and establish personal improvement plans for Functional Specialists to address any development or improvement opportunities. o Participate in the escalation process, identifying operational risks and issues, and act as a decision-maker. o Support the Service Delivery Manager in managing internal and customer-driven changes and initiatives. o Maintain strong communication links with internal and external stakeholders. o Complete any other duties as directed by the Service Delivery Manager or senior management team to ensure successful delivery of the assessment service. What we’re looking for: o Full UK driving license and access to own vehicle. o Proven experience in managing large teams of 15 or more. o Extensive experience in performance management. o Team leadership and coaching experience. o Demonstrable planning, leadership, motivational and organisational skills. o Ability to work in a high pressure environment, managing detailed operational deliverables, meeting targets and business plans. o Proven track record of building and developing teams. o Ability to develop and deliver presentations to direct reports and stakeholders. o Strong analytical skills – familiar with MS Office, particularly Excel/Word and PowerPoint. About HAAS The Health Assessment Advisory Service (HAAS) arranges and carries out assessments for the Department for Work and Pensions (DWP) and the Department for Communities (DfC). The purpose of the assessment is to understand how an illness or disability affects a person’s daily life. After the assessment, the DWP/DfC makes the decision as to whether the individual will receive benefits. What’s in it for you? o A competitive salary of £41,000 p/a o 25 days’ holiday (rising to 27) with the opportunity to buy extra leave o The opportunity to take a paid day out of the office, volunteering for our charity partners or a cause of your choice o Auto-enrolment to our company pension, life assurance, a cycle2work scheme, 15 weeks’ fully paid maternity, adoption and shared parental leave, paternity pay of two weeks…and plenty more o Voluntary benefits designed to suit your lifestyle – from discounts on retail and socialising, to health & wellbeing, travel and technology o Access to our Employee Network Groups, which represent every strand of diversity and allow colleagues to connect and learn from each other on an open, inclusive platform You’ll get the chance to follow your chosen career path anywhere in Capita. You’ll be joining a network of experienced, innovative and dedicated individuals across multiple disciplines and sectors. There are countless opportunities to learn new skills and develop in your career, and we’ll provide the support you need to do just that. Our purpose is to create a better outcome for you. What we hope you’ll do next: Choose ‘Apply now’ to fill out our short application, so that we can find out more about you. Equal Opportunities At Capita, we’re committed to providing an inclusive, barrier-free recruitment process and working environment for everyone. We want everyone to have the best chance of succeeding as they move through their application and start their career with us. We are an equal opportunity and Disability Confident employer, we want to hear from you if you’d like to discuss any adjustments you might need during your recruitment process. Please email reasonableadjustments@capita.com or call 07784 237318 and we’ll get back to you to discuss. For more information about equal opportunities and the types of adjustments we can offer, please visit the Capita Careers website. If you have a question that does not relate to adjustments during your recruitment process, please email our Talent Acquisition team - CPScareers@capita.com Job title: Team Manager Job Description: What you’ll be doing: - Focus on business objectives and understand the importance of achieving internal and external service levels to eliminate financial penalties, improve customer satisfaction, and reduce complaints. - With the support of Capita policies and local initiatives, you will be responsible for managing human resources and making key decisions. This includes developing your direct reports through personal accountability and effective performance management. You will achieve this by setting objectives, conducting 1-2-1 meetings and appraisals, overseeing recruitment and selection, providing coaching, and managing absences and disciplinary actions. - Proactively motivate staff, develop a team ethos, and minimize staff absence and attrition. - Ensure all defined processes and reporting requirements are followed by team members. - Use management information to understand quality issues, KPIs, and trends, and identify and deliver remedial actions and improvement opportunities. - Collaborate with the Quality Learning Support team (QLS), Regional Clinical Team, and Clinical Governance Team to monitor quality and coach Functional Specialists. - Ensure coaching targets are achieved and establish personal improvement plans for Functional Specialists to address any development or improvement opportunities. - Participate in the escalation process, identifying operational risks and issues, and act as a decision-maker. - Support the Service Delivery Manager in managing internal and customer-driven changes and initiatives. - Maintain strong communication links with internal and external stakeholders. - Complete any other duties as directed by the Service Delivery Manager or senior management team to ensure successful delivery of the assessment service. What we’re looking for: - Full UK driving license and access to own vehicle. - Proven experience in managing large teams of 15 or more. - Extensive experience in performance management. - Team leadership and coaching experience. - Demonstrable planning, leadership, motivational and organisational skills. - Ability to work in a high pressure environment, managing detailed operational deliverables, meeting targets and business plans. - Proven track record of building and developing teams. - Ability to develop and deliver presentations to direct reports and stakeholders. - Strong analytical skills – familiar with MS Office, particularly Excel/Word and PowerPoint. About HAAS The Health Assessment Advisory Service (HAAS) arranges and carries out assessments for the Department for Work and Pensions (DWP) and the Department for Communities (DfC). The purpose of the assessment is to understand how an illness or disability affects a person’s daily life. After the assessment, the DWP/DfC makes the decision as to whether the individual will receive benefits. What’s in it for you? ​ - A competitive salary of £41,000 p/a - 25 days’ holiday (rising to 27) with the opportunity to buy extra leave - The opportunity to take a paid day out of the office, volunteering for our charity partners or a cause of your choice - Auto-enrolment to our company pension, life assurance, a cycle2work scheme, 15 weeks’ fully paid maternity, adoption and shared parental leave, paternity pay of two weeks…and plenty more - Voluntary benefits designed to suit your lifestyle – from discounts on retail and socialising, to health & wellbeing, travel and technology - Access to our Employee Network Groups, which represent every strand of diversity and allow colleagues to connect and learn from each other on an open, inclusive platform You’ll get the chance to follow your chosen career path anywhere in Capita. You’ll be joining a network of experienced, innovative and dedicated individuals across multiple disciplines and sectors. There are countless opportunities to learn new skills and develop in your career, and we’ll provide the support you need to do just that. Our purpose is to create a better outcome for you. What we hope you’ll do next: Choose ‘Apply now’ to fill out our short application, so that we can find out more about you. Equal Opportunities At Capita, we’re committed to providing an inclusive, barrier-free recruitment process and working environment for everyone. We want everyone to have the best chance of succeeding as they move through their application and start their career with us. We are an equal opportunity and Disability Confident employer, we want to hear from you if you’d like to discuss any adjustments you might need during your recruitment process. Please email reasonableadjustments@capita.com or call 07784 237318 and we’ll get back to you to discuss. For more information about equal opportunities and the types of adjustments we can offer, please visit the Capita Careers website. If you have a question that does not relate to adjustments during your recruitment process, please email our Talent Acquisition team - CPScareers@capita.com Location: Home-Based - GBR, United Kingdom Time Type: Full time Contract Type: Permanent

Biostatistics Manager remote type Remote locations US - California - Thousand Oaks time type Full time job requisition id R-241908 Career Category Quality Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Biostatistics Manager What you will do Let’s do this. Let’s change the world. In this vital role you will ensure all statistical aspects pertaining to clinical activities meet required standards and are statistically correctly. The Biostatistics Manager will influence study design, defending statistical approaches both internally and externally ensuring strict adherence to all Amgen’s Policies, SOPs and other controlled documents. You will also lead on one complex or multiple less complex studies and projects. - Providing statistical contributions, statistical review and quality control of Key Design Elements (KDE) protocols, randomization specifications, Statistical Analysis Plans (SAPs), Table, Listing and Graph (TLG) shells, Submission Data File (SDF) specifications, other key-study related documentation, protocol deviations, Flash Memos, Clinical Study Reports (CSRs), clinical publications, and other communications - Completing statistical analysis of individual studies/projects - Publishing applied research in scientific journals and books, and give presentations on statistical methodology in the biopharmaceutical setting at external scientific meetings (biopharmaceutical industry and academic meetings) - Being familiar with statistical policy and strategy at Amgen - Staying abreast of latest developments in the field of statistics in drug development and contribute to scientific advances in the field - Communicating the role of the Global Biostatistics department, and may contribute to statistical training within Global Biostatistics and within Amgen - Assisting in the review of Amgen Policies, SOPs and other controlled documents - Assisting with study and systems audits conducted by Amgen CQA and external bodies - Serving as team member of change / process improvement initiatives” What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a detail oriented person with these qualifications. Basic Qualifications: Doctoral degree in Statistics/Biostatistics or other subject with high statistical content OR Currently enrolled in PhD program in Statistics/Biostatistics or other subject matter with high statistical content, and must complete all requirements necessary to obtain Doctoral Degree in the PhD program prior to employment start date OR Master's degree in Statistics/Biostatistics or other subject with high statistical content and 3 years of statistics experience Preferred Qualifications: ·Doctorate in Statistics/Biostatistics with 1 year of post-graduate statistical experience in the pharmaceutical industry or medical research ·Excellent computing, modelling and simulation skills using R, SAS, WinBugs, FACTS, etc. ·Experience in designing, analyzing and reporting of clinical trials within Pharmaceutical/Biotechnology/Public Health setting in Industry, Government or Academia ·Proactive and efficient in learning emerging adaptive designs and building simulation tools for wide use and applications ·Knowledge of Bayesian statistics ·Extensive knowledge of simulation and modeling techniques ·Work well with both statistical colleagues and cross functional teams ·Good communication skills (written and oral) What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: - A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts - A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan - Stock-based long-term incentives - Award-winning time-off plans - Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Salary Range 131,551.95USD -177,982.05 USD

Title: LVN Case Manager Location Sacramento County, CA Employment Type Full time Location Type Hybrid Department Enhanced Care Management Compensation - LVN$32 – $38 per hour Great humans deserve great benefits! At Vynca, full time employees are eligible for benefits such as: medical, dental, and vision insurance, income protection benefits, flexible PTO, company holidays, 401k, and access to other wellness benefits. We offer competitive compensation based on factors such as experience, skills, location, company needs, and market demands. For field roles, mileage reimbursement will be provided per IRS guideline Job Description: Join the dynamic journey at Vynca, where we're passionate about transforming care for individuals with complex needs. We’re more than just a team; we're a close-knit community. Our shared commitment to caring for each other and those we serve is what sets us apart. Guided by our unwavering core values: Excellence, Compassion, Curiosity, and Integrity, we forge paths of success together. Join us in this transformative movement where you can contribute to making a profound difference every day. At Vynca, our mission is to provide comprehensive care for more quality days at home. About the job Internal Title: Clinical Lead Care Manager We are looking for a highly skilled Clinical Lead Care Manager (CLCM) to join our team serving Sacramento County, CA. Reporting to the ECM Clinical Manager, the CLCM acts as the client’s primary point of contact, partnering with healthcare providers and support services to ensure coordinated, aligned, and comprehensive care. The CLCM manages client cases, coordinates health care benefits, provides education and facilitates member access to care in a timely and cost-effective manner. The CLCM collaborates and communicates with the client’s caregivers/family support persons, other providers, and others in the Care Team to promote wellness, recovery, independence, resilience, and member empowerment, while ensuring access to appropriate services and maximizing member benefit. This is a hybrid position that requires traveling throughout the Sacramento County area up to 5 days per week. Candidates wishing to be considered must reside within 25-miles of the assigned territory due to frequency of travel. This is a critical role and we're looking to fill it as soon as possible. What you’ll do Hybrid (in-person and remote) care management duties as described below: - Assess member needs in the areas of physical health, mental health, SUD, oral health, palliative care, memory care, trauma-informed care, social supports, housing, and referral and linkage to community-based services and supports - Oversees the development of the client care plans and goal settings - Offer services where the member resides, seeks care, or finds most easily accessible, including office-based, telehealth, or field-based services - Connect clients to other social services and supports that are needed - Advocate on behalf of the client with health care professionals (e.g. PCP, etc.) - Utilize evidence-based practices, such as Motivational Interviewing, Harm Reduction, and Trauma-Informed Care principles - Conduct outreach and engagement activities in order to facilitate linkage to the ECM program and log activity in the Client Relationship Management (CRM) system - Evaluate client’s progress and update SMART goals - Provide mental health promotion - Arrange transportation (e.g., ACCESS) - Complete all documentation, including outcome measures within the timeframes established by the individual care plans - Maintain up-to-date patient health records in the Electronic Medical Record (EMR) system and other business systems - Complete monthly reporting to ensure program compliance - Attend training as assigned Your experience & qualifications - Active California Licensed Vocational Nurse (LVN) license required - Willing and able to work Monday-Friday 8:30am-5:00pm, both in the field and remotely - 2+ years of experience as a care manager, care navigator, or community health worker supporting vulnerable populations - Bilingual, Spanish/English, required - Working knowledge of government and community resources related to social determinants of health - Excellent oral and written communication skills - Positive interpersonal skills required - Clean driving record, valid driver's license, and reliable transportation - Must have general computer skills and a working knowledge of Google Workspace, MS Office, and the internet Additional Information - The hiring process for this role may consist of applying, followed by a phone screen, online assessment(s), interview(s), an offer, and background/reference checks. - Background Screening: A background check, which may include a drug test or other health screenings depending on the role, will be required prior to employment. - Job Description Scope: This job description is not exhaustive and may include additional activities, duties, and responsibilities not listed herein. - Vaccination Requirement: Employees in patient, client, or customer-facing roles must be vaccinated against influenza. Requests for religious or medical accommodations will be considered but may not always be approved. - Employment Eligibility: Compliance with federal law requires identity and work eligibility verification using E-Verify upon hire. - Equal Opportunity Employer: At Vynca Inc., we embrace diversity and are committed to fostering an inclusive workplace. We value all applicants regardless of race, color, religion, age, national origin, ancestry, ethnicity, gender, gender identity, gender expression, sexual orientation, marital status, veteran status, disability, genetic information, citizenship status, or membership in any other protected group under federal, state, or local law.