At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees. Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so. Does this inspire you and feel like a fit? Then we would love to have you join us! The Associate Director - Statistical Computing Environment (SCE) serves as the Business System Owner for Genmab’s validated Statistical Computing Platform. This role is accountable for ensuring the platform remains fit for intended use and compliant with global GxP requirements while leading business adoption, roadmap evolution, and operational excellence. Operating within the Programming Process, Standards, and Technology organization, the Associate Director partners with IT, QA, vendors, and the cross-functional user community to maintain the validated state of the SaaS-based computing environment and drive continuous improvement of the platform. Responsibilities - Serve as Business System Owner for the Statistical Computing Environment, accountable for maintaining the validated state of the GxP platform in partnership with IT, QA, and vendors. - Lead validation lifecycle activities from the business perspective, including change impact assessment, user acceptance testing (UAT), regression testing, and approval of vendor validation documentation. - Manage and assess vendor-driven system releases and changes, ensuring appropriate risk evaluation, documentation updates, communication, and testing prior to deployment. - Conduct and document periodic system review to confirm continued fitness for intended use, access governance, compliance posture, and vendor performance. - Participate in deviation management and CAPA activities related to system functionality or compliance. - Ensure business-level compliance with global regulations and maintain inspection readiness of documentation, processes, and system controls. - Define and prioritize platform roadmap in alignment with clinical and statistical programming strategy. - Lead operational oversight and end-user support, ensuring high service levels and effective issue resolution. - Lead end-user training and engagement initiatives to communicate system updates and drive adoption of new capabilities. - Author and maintain controlled process documentation governing system usage, environment management, and user access. - Partner with IT and QA on supplier qualification, vendor oversight, and review of audit/SOC documentation for the SaaS platform. - Represent Statistical Programming in cross-functional governance forums to align system capabilities with enterprise needs. - Support internal audits and regulatory inspections as the business representative for the Statistical Computing Environment. - Collaborate with IT, Digital Development, and other business product owners to enable platform integrations and interoperability across our end-to-end workflow. Qualifications - Bachelor’s or Master’s degree in statistics, biostatistics, computer science, or related field and/or 10+ years of experience in pharmaceutical/biotech environments supporting validated GxP computerized systems. - Demonstrated experience serving as Business or Application System Owner for a GxP platform, preferably in a SaaS or cloud-hosted model. - Strong working knowledge of 21 CFR Part 11, EU Annex 11, GAMP 5, GxP SDLC, change control, and data integrity principles (ALCOA+). - Experience reviewing vendor validation documentation and leading UAT/regression testing in a regulated environment. - Experience supporting inspection readiness, internal audits, and regulatory inspections. - Practical knowledge of statistical programming environments (e.g., SAS, R) and associated file, package, and workflow management. - Experience operating within a vendor-based validation model and assessing business impact of SaaS platform releases. - Strong analytical and organizational skills with demonstrated accountability and ability to manage competing priorities. - Knowledge of open-source package governance and reproducible environment strategies, a plus. - Active participation in relevant industry organizations (e.g., PHUSE, CDISC), a plus. For US based candidates, the proposed salary band for this position is as follows: $164,080.00---$246,120.00 The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives. When you join Genmab, you’re joining a culture that supports your physical, financial, social, and emotional wellness. Within the first year, regular full-time U.S. employees are eligible for: - 401(k) Plan: 100% match on the first 6% of contributions - Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance - Voluntary Plans: Critical illness, accident, and hospital indemnity insurance - Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave - Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support - Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses About You - You are genuinely passionate about our purpose - You bring precision and excellence to all that you do - You believe in our rooted-in-science approach to problem-solving - You are a generous collaborator who can work in teams with a broad spectrum of backgrounds - You take pride in enabling the best work of others on the team - You can grapple with the unknown and be innovative - You have experience working in a fast-growing, dynamic company (or a strong desire to) - You work hard and are not afraid to have a little fun while you do so! Locations Genmab maximizes the efficiency of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are crafted as open, community-based spaces that work to connect employees while being immersed in our powerful laboratories. Whether you’re in one of our office spaces or working remotely, we thrive on connecting with each other to innovate. About Genmab Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines. Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X. Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website Job Applicant Privacy Notice (genmab.com). Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.

• Successful execution of regulatory risk adjustment audits minimizing financial impacts to Humana through strong operational execution • identifying areas of opportunity for improvement and leveraging key partnerships with Quality Cost & Strategy partners • market risk adjustment associates, and other associates across Humana, including legal and regulatory compliance partners • Operational excellence of all coding quality audits the team conducts • Drive development of analytics of audit data and results to inform future strategy to minimize Humana’s risk regarding risk regarding risk adjustment data • Provide compliance oversight over all risk adjustment activities through execution of clearly defined programs, identified and defined key metrics and reporting • Establish and manage goals, priorities, staffing and budgets for the team.

Manulife is a leading international financial services provider, helping people make decisions easier and lives better. Help shape the future you want to see — and discover that better can take you anywhere you want to go. The Senior Underwriting Director provides guidance to more junior staff and assists Underwriting Management with research and training of Underwriting Staff. The incumbent will also take the lead on high scope and complex Underwriting department projects. Position Responsibilities: - Manage all aspects of potentially unlimited total line in close association with reinsurers. - Select and classify risk according to company philosophy and standards. - Participate in and provide a leadership resource for projects in the Underwriting Department. - Be an information resource for underwriters at all levels. - Combine appropriate attention to established standards of turnaround with higher level of service and professionalism. - Analyze and interpret medical, non-medical, and financial information. - Make decisions within approval limits. - Ensure that complete and appropriate underwriting requirements are completed while at the same time practicing effective expense management. - Management of reinsurance process to ensure maximum capacity while avoiding reinsurance “gridlock”. - Management/control of diversification process as “lead” underwriter on very largest of cases. - Manage referral/consultation process to ensure that timely and accurate decisions are provided. - Manage mortality on preferred block of business, through flex guidelines to ensure pricing/mortality expectations are met. - Ensure consistency and adherence to established departmental guidelines though referral process. - Actively participate in the development, implementation and management of New Business initiatives. - Actively participate in the ongoing training and professional development of underwriting team. - Act as resource/mentor to other members of the underwriting team, particularly at the consultant level. - Champion appeals and business decisions in concert with the Chief Underwriter. - Maintain positive and effective relationships with internal and external partners. Required Qualifications: - Post-secondary education or equivalent work experience. - Minimum 15 years underwriting experience. - Expert knowledge and understanding of medical, non-medical and financial underwriting principles and practices. - In depth knowledge of unique estate, business and insurance planning tools and techniques. - In depth/current knowledge of political, economic, financial and legislative events which may impact client needs. - Expert knowledge of company’s insurance product portfolio and ability to marry that knowledge with an understanding of producer/client need. - Expert knowledge of reinsurance, market place treaties, agreements and available capacity. - Exceptional priority management with ability to work effectively under deadlines, balance published service times with an appropriate customer. - Strong organizational, analytical and problem-solving skills. - Effective presentation skills. - Strong written and verbal communication skills. - Strong customer service orientation. - Knowledge of and ability to apply project management skills. - Expert knowledge of insurance contract law and state legislative requirements as they relate to the underwriting and issue of insurance contracts. - High level understanding of product pricing principals. - Balance appropriate attention to expense management against the need to secure sufficient and appropriate underwriting information to make the best decision for the client and the company. - Actively assist field personnel in positioning the Company as the lead underwriter in the market. - Actively pursue opportunities for development of self and team. - Develop and maintain effective working relationships with all field personnel and reinsurers. - Keep current and up to date with the changing compliance and insurance regulatory environment. - Keep current and up to date with changes in estate/insurance planning strategies. - Identify departmental problems, recommend solutions and assist in implementation of change including manual updates Preferred Qualifications: - Applicable underwriting and insurance designations preferred. Working Conditions: • Some travel • Concentration • Visual • Exposure to Weather When you join our team: - We’ll empower you to learn and grow the career you want. - We’ll recognize and support you in a flexible environment where well-being and inclusion are more than just words. - As part of our global team, we’ll support you in shaping the future you want to see. The role being advertised is an existing vacancy. About Manulife and John Hancock Manulife Financial Corporation is a leading international financial services provider, helping people make their decisions easier and lives better. To learn more about us, visit https://www.manulife.com/en/about/our-story.html. Manulife is an Equal Opportunity Employer At Manulife/John Hancock, we embrace our diversity. We strive to attract, develop and retain a workforce that is as diverse as the customers we serve and to foster an inclusive work environment that embraces the strength of cultures and individuals. We are committed to fair recruitment, retention, advancement and compensation, and we administer all of our practices and programs without discrimination on the basis of race, ancestry, place of origin, colour, ethnic origin, citizenship, religion or religious beliefs, creed, sex (including pregnancy and pregnancy-related conditions), sexual orientation, genetic characteristics, veteran status, gender identity, gender expression, age, marital status, family status, disability, or any other ground protected by applicable law. It is our priority to remove barriers to provide equal access to employment. A Human Resources representative will work with applicants who request a reasonable accommodation during the application process. All information shared during the accommodation request process will be stored and used in a manner that is consistent with applicable laws and Manulife/John Hancock policies. To request a reasonable accommodation in the application process, contact hr@manulife.com. Referenced Salary Location USA, South Carolina - Full Time Remote Working Arrangement Remote Salary range is expected to be between $128,550.00 USD - $222,820.00 USD Employees also have the opportunity to participate in incentive programs and earn incentive compensation tied to business and individual performance. The actual salary will vary depending on local market conditions, geography and relevant job-related factors such as knowledge, skills, qualifications, experience, and education/training. If you are applying for this role outside of the primary location, please contact hr@manulife.com for the salary range for your location. Manulife/John Hancock offers eligible employees a wide array of customizable benefits, including health, dental, mental health, vision, short- and long-term disability, life and AD&D insurance coverage, adoption/surrogacy and wellness benefits, and employee/family assistance plans. We also offer eligible employees various retirement savings plans (including pension/401(k) savings plans and a global share ownership plan with employer matching contributions) and financial education and counseling resources. Our generous paid time off program in the U.S. includes up to 11 paid holidays, 3 personal days, 150 hours of vacation, and 40 hours of sick time (or more where required by law) each year, and we offer the full range of statutory leaves of absence. We use data and analytics technologies, such as artificial intelligence (AI), and automated processing tools, to analyze and process the information you provide to us or third parties in the application process. For more information, please refer to our personal information collection statement. Know Your Rights I Family & Medical Leave I Employee Polygraph Protection I Right to Work I E-Verify Company: John Hancock Life Insurance Company (U.S.A.)

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: The AD BPO Global APQR owns the process which captures and examines BeOne’s product knowledge throughout the commercial lifecycle, maintains oversight on process capability through data trending and statistical analysis of critical variables, ensuring process(es) are robust, in continued state of validation and continuously improving. As a Product Data Quality Steward, ensures, the reliability and access to product information, process knowledge across functions via QMS systems. Provides second line technical/scientific process support. The Data Quality Steward will support cross-functional collaboration, drive process improvements and enhance the organization's approach to quality governance using evidence backed decision making. This individual will collaborate across functions and sites to drive continuous improvement, ensure regulatory compliance, and build a robust knowledge-sharing and risk management culture. - As Business Process Owner for the Global APQR process, contribute to product quality performance monitoring, identifying trends and driving improvements. - Collaborate with R&D, manufacturing (CMC) and regulatory teams to ensure quality considerations are embedded in new product development and lifecycle management. - Manage change tracking and implementation for actions related to Regulatory CMC commitments - Lead or participate in cross-functional teams to improve quality systems and address systemic challenges. - Represent the Quality Organization at platform level through participation in molecule level governance meetings and forums. - Support regulatory inspections and audits, ensuring alignment with global quality standards and best practices. - Actively mentoring new and existing team members to develop core Product Quality skills and leadership skills - Understanding and responding to the impact of emerging scientific/technical trends and their implications for BeOne / BeiGene Products. - Perform other related responsibilities as assigned. Education and Experience Required: - Bachelor’s degree and 6+ years of experience in quality sciences, quality systems, or related fields within a regulated industry (e.g., pharmaceuticals, biotechnology, medical devices). - Master’s degree and 8 + years' experience preferred Supervisory Responsibilities: - 3 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources. Computer Skills: - Strong PC literacy required; MS Office skills (Outlook, Word, Excel, PowerPoint). - Ability to learn specialized platforms (Veeva, Power BI, Calyx, SAP, etc) and statistical modeling software (Mintab, JMP, Tableau, SciLab, etc.) Other Qualifications: - Advanced degree in life sciences, quality management, or related field - Extensive experience in leading quality investigations, quality risk management, and implementing new technologies. - Expertise in quality systems, regulatory requirements (e.g., FDA, EMA), and risk management frameworks (e.g., ICH Q9). - Strong leadership and problem-solving skills, with the ability to manage complexity and ambiguity. - Experience in developing and delivering global training programs ad fostering SME networks. - Proficiency in quality tools and methodologies (e.g., root cause analysis, Lean, Six Sigma). - Ability to communicate complex information clearly and effectively across business functions Travel: Up to 20% Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. - Fosters Teamwork - Provides and Solicits Honest and Actionable Feedback - Self-Awareness - Acts Inclusively - Demonstrates Initiative - Entrepreneurial Mindset - Continuous Learning - Embraces Change - Results-Oriented - Analytical Thinking/Data Analysis - Financial Excellence - Communicates with Clarity Salary Range: $143,400.00 - $193,400.00 annuallyBeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com.