• Serve as the safety expert of the assigned product(s) within the Rare Disease portfolio • Establish the strategy, direction, and priorities of pharmacovigilance activities • Lead the Safety Analysis Team (SAT), Global Safety Team (GST) and is a core member of the Executive Safety Committee (ESC) • Validate safety signals and lead safety signal assessments • Develop and maintain Core Safety Information (core data sheet, core risks in informed consent forms, etc.) • Prepare/review core and regional risk management plans including additional risk minimization measures • Prepare/review safety sections of periodic aggregate reports • Provide safety input to protocols, statistical analysis plans, and clinical study reports • Prepare/review safety sections of new drug applications and other regulatory filings • Serve as safety expert on Evidence Generation Team for assigned products • Inspection Readiness • Domestic and International travel up to 10%

Position: Medical Director of Utilization Management Location: Remote (Must Reside in NY/NJ/CT) Work Schedule: PER DIEM (5-6 hours/week) Per Diem, hourly physician advisor consultant. Should have flexible schedule to allow coverage for full-time and part-time physicians. Compensation: (Non-exempt) $120 - $125 A little about us VillageCare is a community-based, not-for-profit organization serving people with chronic care needs, as well as seniors and individuals in need of continuing care and managed care services. Our mission is to promote healing, better health and well-being to the fullest extent possible. Our care is offered through a comprehensive array of community and residential programs, as well as managed care. VillageCare has delivered quality health care services to individuals residing within New York City for over 45 years Job Summary: The Medical Director for VillageCareMAX is a physician who serves as clinical lead for the Utilization Management Department and medical quality and cost effectiveness activities. The Medical Director assists the VP of Medical Management to direct and coordinate medical management and quality improvement activities for the Health Plan. Essential Job Functions: - Responsible for providing oversight to the delivery of utilization management (UM) services and resources, consisting of case reviews for organizational determinations, peer to peer reviews and appeals - Utilizes the care management system to document all case reviews - Participates in case rounds/ICT meetings in the development of UM/CM plans for individual members to ensure appropriate continuity of care - Analyzes utilization patterns, trends, and implements strategies to bring utilization patterns in line with expected benchmarks - Responsible for successful compliance with regulatory and contractual requirements for Medical Management functions - Participates in State and Federal Regulatory audits, investigations, surveys, and other reviews by the UM Department - Maintains current knowledge of Federal and State regulatory requirements - Develops and proposes annual goals and provides regular reports on progress toward accomplishing those goals Experience: - This position requires 3-5 years of health plan experience in medical management with Medicare and Medicaid Programs (specifically MLTC, MAP, DSNP and MAPD) - Experience with both inpatient and outpatient utilization management (medical, pharmacy) - Experience with appeal reviews - NY Market Experience - No New York Group or Hospital Affiliations Education and certification: - Medical Doctorate is required for this position. Master's - Degree in public health is also preferred - Certification: Required: Current and unrestricted Physician license to practice in NY - Preferred: Board Certified, preferably internal medicine, geriatrics, emergency Medicine, Family Medicine

• Provide medical monitoring for assigned projects • Function as medical representative on the project team • Provide medical consultation as required or requested to client/sponsor or to other Parexel service groups • Assume the role of Senior Technical Lead in selected circumstances • Review all individual adverse experience reports for accuracy and clinical importance • Characterize relationship to the study drug, severity, and seriousness • Provide reports to FDA or other regulatory agencies and the sponsor summarizing adverse experiences as required • Review data listings of safety data, including adverse experiences, laboratory data, and vital signs data • Review documents for safety issues written by various Parexel divisions • Provide support for preparation of clinical protocols, integrated clinical and statistical summary reports, journal articles, and other documents

CareDx, Inc. is a leading precision medicine solutions company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. CareDx offers products, testing services, and digital healthcare solutions along the pre- and post-transplant patient journey, and is the leading provider of genomics-based information for transplant patients. The Medical Director will be an MD/DO, with training and experience in abdominal transplant, and will lead the efforts to support the abdominal portfolio of the medical and clinical development strategy of CareDx’ pipeline and in-line products. This includes developing clinical trials, research studies, national and international registries, publications and abstracts, medical information activities, thought leader engagement, conferences, and other scientific and medical engagement platforms. The individual will educate and partner with clinical and business leaders, including transplant clinicians and surgeons, other clinical and research transplant personnel, government and private payers, laboratory directors, distributors, and other external stakeholders. Internally, the Medical Director will partner with the functional and business leads, MSL Directors, and Medical Science Liaisons to help prioritize, analyze, propose, and execute clinical and research partnerships to enable the generation and dissemination of evidence regarding CareDx’ broad transplant portfolio. You will have the opportunity to launch and scale CareDx’ new best-in-class offerings and drive the data using this platform to show improved outcomes for solid organ transplant recipients. The role is within the Medical Affairs organization, and a broad CareDx team will collaborate and support the Medical Director’s success, including Research and Development, Marketing, Clinical Operations, Regulatory Affairs, and others. The ideal candidate has a deep understanding of and experience in helping drive end-to-end patient care management at key transplant center(s), developing clinical messaging, engaging scientifically with clinicians and transplant key thought leaders to drive scientific and clinical innovation, generating evidence, and disseminating evidence for transplantation management. A record of accomplishments in transplantation, in-depth clinical knowledge, ability to build senior client relationships, and/or launch new products in an entrepreneurial environment is a strong plus. The position involves frequent travel across the country, working with key transplant centers across the nation, and supporting the Medical Science Liaison team with senior medical leadership where needed. Responsibilities: Medical Strategy & Leadership - Lead and execute Medical Affairs strategies supporting the abdominal transplant portfolio. - Partner closely with Medical Affairs and Clinical Operations leadership to align priorities, strategies, and execution plans and provide proactive updates and reporting on progress toward objectives. - Provide senior medical leadership and support to the Medical Science Liaison team as needed to prioritize scientific engagement, research collaborations, and educational initiatives at key transplant centers. Clinical Development & Evidence Generation - Contribute to the assessment, design, and implementation of sponsored clinical studies, registries, investigator-initiated trials (IITs), grants, and research collaborations. - Collaborate with Clinical Operations and Medical Affairs to propose, implement, and monitor clinical studies in key markets. - Support the generation, analysis, and dissemination of clinical and real-world evidence demonstrating the value of CareDx’s abdominal transplant solutions. Scientific Engagement & External Collaboration - Serve as a senior company representative with external scientific leaders, transplant clinicians and surgeons, patient advocacy groups, and other key stakeholders. - Engage with national and international key opinion leaders to advance scientific dialogue and clinical innovation in abdominal transplantation. - Participate in and support scientific and clinical advisory boards. - Support scientific and clinical initiatives at major transplant and scientific meetings. Medical Education & Scientific Communication - Present scientific and clinical data at customer workshops, symposia, congresses, and professional meetings. - Support scientific bureau activities and deliver presentations on behalf of CareDx. Cross-Functional Partnership - Function as the primary clinical resource for Business and Market Development teams, providing scientific and clinical input into product and business strategy. - Collaborate with Marketing, R&D, PLM, Regulatory Affairs, and other internal teams to ensure appropriate medical input across the product lifecycle. - Coordinate across the CareDx organization to ensure appropriate resources are aligned to support new clinical and scientific opportunities. Qualifications Required - MD or DO with 5 years of post-training clinical experience - Demonstrated experience in abdominal organ transplantation (kidney, liver, pancreas, and/or intestine) - Strong understanding of transplant care pathways and end-to-end patient management - Experience engaging with transplant clinicians, surgeons, and key opinion leaders Preferred - Experience in clinical research, molecular diagnostics, and/or advanced transplant technologies - Advanced degree (PhD, MBA, or equivalent) strongly desired - Experience contributing to product launches or working in an entrepreneurial, high-growth environment Core Competencies - Passion for improving outcomes for transplant patients - Proven ability to generate and communicate scientific and clinical evidence - Strong executive presence with the ability to present to senior leaders and external experts - Results-oriented, with a track record of ownership and accountability - High initiative, intellectual curiosity, and ability to manage multiple priorities independently - Excellent collaboration and cross-functional partnership skills Travel - Domestic and international travel required, up to 50% Additional Details: Every individual at CareDx has a direct impact on our collective mission to improve the lives of organ transplant patients worldwide. We believe in taking great care of our people, so they take even greater care of our patients. Our competitive Total Rewards package for US Employees includes: - Competitive base salary and incentive compensation - Health and welfare benefits, including a gym reimbursement program - 401(k) savings plan match - Employee Stock Purchase Plan - Pre-tax commuter benefits - And more! - Please refer to our page to view detailed benefits at https://caredx.com/company/careers In addition, we have a Living Donor Employee Recovery Policy that allows up to 30 days of paid leave annually to a full-time employee who makes the selfless act of donating an organ or bone marrow. With products that are making a difference in the lives of transplant patients today and a promising pipeline for the future, it’s an exciting time to be part of the CareDx team. Join us in partnering with transplant patients to transform our future together. CareDx, Inc. is an Equal Opportunity Employer-vets/disabled, and participates in the E-Verify program. By proceeding with our application and submitting your information, you acknowledge that you have read our U.S. Personnel Privacy Notice and consent to receive email communication from CareDx. ***We do not accept resumes from headhunters, placement agencies, or other suppliers that have not signed a formal agreement with us.*** Certain jurisdictions require notice of how we use and protect your personal information. For more information, please read our Privacy Policy #LI-Remote This is the anticipated base salary range in the United States. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and length of experience within the job, the type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states. Remote: US only roles $300,000—$350,000 USD