GlaxoSmithKline - GSK

Title: Global Medical Director, Oncology Location: Collegeville United States Site Name: USA - Pennsylvania - Upper Providence, Baar Onyx, Home Worker - USA, UK - London, USA - North Carolina - Durham, USA - Pennsylvania - Philadelphia Job Description: Position Summary You will lead global medical activities for oncology assets and work closely with research, commercial, clinical operations, and local medical teams. You will shape evidence generation, guide external scientific engagement, and help translate clinical insights into patient impact. We value collaboration, clear scientific judgement, practical leadership, and a focus on improving patient outcomes. This role offers growth, meaningful impact, and the chance to unite science, technology and talent to get ahead of disease together. Responsibilities This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: - Lead development and delivery of the global medical affairs plan and the integrated evidence plan for oncology assets. - Drive above-country medical activities such as advisory boards, congress strategy, symposia, and scientific education. - Own scientific engagement with external experts, patients, payers and regulators to gather insights and shape strategy. - Partner with research and development to design and prioritize global and supportive clinical studies, including review of investigator-initiated proposals. - Support brand and launch planning by providing medical input to local operating companies and commercial teams. - Provide medical governance and review scientific materials to ensure accuracy, compliance and clear communication. Why You? We are seeking people who bring scientific credibility, practical leadership and a collaborative mindset. You will join a global team and have a direct line of influence on evidence generation and medical strategy for oncology. The role is based in the United States and is hybrid, with a mix of remote and on-site work expected. Travel will be required to meet with colleagues, partners and external experts. Basic Qualification We are seeking professionals with the following required skills and qualifications to help us achieve our goals: - MD, PharmD, or PhD with relevant clinical or scientific experience in oncology. - 5+ years' experience in medical affairs, clinical development, or related roles in oncology. - Demonstrated experience leading global medical strategies and evidence generation plans. - Strong understanding of clinical trial design and operational experience with global studies. - Experience engaging external experts, advisory boards, and congress planning. - Excellent written and verbal communication in English and proven ability to present complex data clearly. Preferred Qualification If you have the following characteristics, it would be a plus: - Deep disease knowledge in prostate or lung oncology. - Experience with expanded access programs or post-approval study requirements. - Prior experience working across time zones and in a matrix global organization. - Familiarity with promotional review processes and medical governance standards. - Track record of publications, abstracts or congress leadership. - Experience mentoring and developing early-career medical colleagues. How to Apply We would love to hear from you. Please submit your CV and a short cover letter that explains why this role matters to you and how you would contribute. If you need adjustments during the recruitment process to support inclusion, tell us and we will work with you. The US annual base salary for new hires in this position ranges from $198,000 to $330,000. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements.

Title: REMS Audit Oversight Lead Location :East Coast United States Work Type: Remote Job ID:439863 Job Description: At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together. This is a U.S.-based remote role aligned to East Coast working hours. Some travel may be required. Find out more: Our approach to R&D You will lead oversight of Risk Evaluation and Mitigation Strategy (REMS) audit activities across the United States. You will design and manage REMS compliance audit programs, partner with cross-functional teams, and ensure compliance with regulatory requirements. We value clear thinking, collaboration, and a focus on continuous improvement. This role offers growth through high-impact work that helps protect patients and supports GSK's mission of uniting science, technology and talent to get ahead of disease together. This role will provide you the opportunity to lead key activities to progress your career. These responsibilities include some of the following: - Develop and manage a risk-based REMS audit compliance program for products and third-party partners. - Plan and oversee execution of compliance, audits by a third party to assess compliance with REMS requirements, regulations, and internal standards. - Central point to trend audit findings and work with stakeholders to define and track corrective and preventative actions (CAPA). - Serve as the subject matter expert during regulatory inspections and support inspection readiness activities. - Create metrics and trend reports to identify systemic risks and recommend process improvements. - Coach and mentor colleagues on audit methodology, REMS compliance, and quality expectations. Collaboration and impact You will work closely with regulatory affairs, medical affairs, safety, commercial, legal, and external partners. You will translate regulatory expectations into practical audit plans. You will influence change by presenting clear, evidence-based recommendations. You will help shape practices that protect patients and support timely access to medicines. Why You? Basic Qualification We are seeking professionals with the following required skills and qualifications to help us achieve our goals: - Must reside within territory for consideration with access to a major airport. - Bachelor's degree in life sciences, healthcare, quality, or related field. - Minimum of 5 years' experience in quality assurance, regulatory compliance, or audit within the pharmaceutical or healthcare industry. - Direct experience with REMS programs, including Experience planning and overseeing REMS audits and managing CAPA follow-up. - Experience with U.S. regulatory requirements for risk management and pharmacovigilance. Preferred Qualification If you have the following characteristics, it would be a plus: - Advanced degree in life sciences, pharmacy, public health, or related field. - Strong written and verbal communication skills with experience presenting audit findings to stakeholders. - Knowledge of pharmacovigilance systems and safety reporting requirements. - Experience working with cross-functional global teams and third-party vendors and regulatory bodies. - Experience with vendor oversight. - Proficiency with data analytics, or quality metrics. - Experience operating in environments requiring rapid operational escalation and high-volume audit activities. Working model and travel - This is a U.S.-based remote role aligned to East Coast working hours. - Some domestic travel (up to 10%) may be required for stakeholder meetings. #LI-Remote The US annual base salary for new hires in this position ranges from $126,750 to $211,250. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Title: Director, Global Real-World Evidence & Health Outcomes Scientist, Oncology Location: Collegeville, Pennsylvania; London, United Kingdom Epidemiology and Health Outcomes Job Description: Site Name: USA - Pennsylvania - Upper Providence, UK - London - New Oxford Street Job Purpose For drugs to be successful, there must be robust health outcomes data to support launch optimization, reimbursement and maintain market positioning. Specifically, evidence must be generated and maintained throughout the product lifecycle as the standard of care changes, new competitors are introduced, and patents expire on existing competitors. The landscape is evolving quickly as trials demonstrating efficacy in an area of unmet need may receive expedited review, or orphan product status designation which affects both GSK and competitors launch timelines and approval requirements. More of our customers are developing sophisticated internal health outcomes capabilities and access to real world data that can be used to better understand unmet needs and real-world effectiveness of our medicines. We need to better understand how our customers define value and to effectively collaborate with them to ensure we are generating value evidence data that includes real world evidence and cost effectiveness analyses that are impactful for payers, health systems, providers, and patients. The role of Director, Global Real-World Evidence & Health Outcomes Research Scientist is critical to achieving this ambition by supporting asset teams to ensure that each medicine GSK brings to market is supported by scientifically credible, high quality, evidence that drives competitiveness and strong evidence-based product positioning, value propositions and value-based pricing. The role is critical to support the alignment of evidence with evidentiary requirements of customers responsible for marketing authorization, recommendation and reimbursement leading to successful patient access, product use and commercial success. Responsibilities This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: - Plan, design and execute multiple studies for a given asset and manage timelines, deliverables, and budget. - Assure quality of deliverables, including review and sign off project specifications, protocols, data analysis plans, final study reports, abstracts, posters and manuscripts, in adherence to SOPs. - Identify resources, references and analyses to inform scientific design and advise internal experts (medical affairs, clinical, commercial/market access) and external experts as needed in support of the asset team. - Translate needs for evidence into study concepts in alignment with strategic objectives and vision for the asset, e.g. development of study protocols and proposing innovative and cost-effective ways of developing and executing studies. - Develop and maintain a good working knowledge of real-world data resources, existing partnerships and public initiatives and become the point person for select sources to advise on their suitability to address given research questions. - Develop a deep understanding of customers' needs, including clinicians and HTA requirements, and their acceptance of different types of evidence and impact of that evidence to their decision making. - Collaborate with internal teams and participate in best practice sharing sessions across the non-interventional study organization. - Build strong working relationships with stakeholder groups across medical, market access, R&D and commercial to ensure strategic alignment and optimal cross-functional collaboration and communication. - Ensure key stakeholders, including TA aligned business leaders, are regularly updated on plans through periodic reporting. - Develop excellent working relationships with external thought leaders to ensure appropriate methods and research agendas are applied, in accordance with GSK policies. Why You? Basic Qualification We are seeking professionals with the following required skills and qualifications to help us achieve our goals: - MSc, or equivalent in health outcomes, health economics, epidemiology, pharmacy, health or life sciences. - 3+ years of experience working in the pharmaceutical industry, preferably in a multi-national company. - Experience in planning and delivering individual projects, managing budgets and working within a matrix setting. - A history of designing a variety of RWE studies including prospective observational studies, cross-sectional and retrospective cohort studies, chart reviews, and database analyses . - Proficiency in utilizing evidence for the development of HTA submissions, reimbursement and/or medical engagements. - A track record of delivering robust payer evidence and credibility to engage meaningfully with external experts and leaders in the field. - Expertise with the diversity and complexity of healthcare markets, health technology assessment agencies, and reimbursement decision making globally, in region and local markets. - Experience in communicating technical and complex concepts and results to various audiences to impact decision-making. Preferred Qualification If you have the following characteristics, it would be a plus: - Advanced scientific degree, e.g. PhD, PharmD or equivalent in Health Economics, Outcomes Research, Epidemiology or similar. - Experience in Oncology or Hematology. - Experience in Global and Country roles in oncology. - Launch experience. What we value in you - Curiosity and continuous learning about evolving methods and data sources. - Clear, direct communication and collaborative working style. - Rigour in methods paired with practical focus on timely, decision-ready evidence. - Commitment to inclusion and respectful teamwork. #LI-GSK #Remote-GSK The US annual base salary for new hires in this position ranges from $204,000 to $340,000. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Title: External Quality Small Molecule Americas Lead Location: Durham United States Quality ID: 438228 Job Description: This position is responsible is for the Quality oversight of assigned Contract Manufacturing Organisations (CMOs) in an External Manufacturing specific Region to ensure MAH's product quality, compliance and reputation is protected. This role will be accountable for establishing and maintaining an effective working relationship with the key contacts at each of the assigned CMO(s) and with internal stakeholders. These include Procurement, Technical, Supplier Relationship, Regulatory, Business Development, Production, Site Management and other related GSK functions. Key Responsibilities - Lead Quality Agreement negotiations with CMOs and implement Quality Systems performance management, including KPI oversight per contractual requirements. - Ensure regulatory compliance by managing the flow of regulatory information between GSK and releasing sites as governed by Quality Agreements. - Monitor CMO quality performance, drive corrective actions, and assess KPIs (e.g., complaints, deviations) to identify continuous improvement opportunities. Apply risk‑management tools, escalate significant risks, and support RMS reporting to governance bodies (Quality Council, LIC, PIRC). Conduct purpose-driven GEMBA walks per the GEMBA Plan. - Partner with cross-functional teams (EM Procurement, PQTS+, Quality, Technical, Supply) to identify, communicate, and resolve quality or compliance risks to ensure consistent supply of quality products. - Collaborate with CMOs to ensure robust quality and manufacturing system outputs, including batch records, deviation investigations, change controls, validations, APRs, and product disposition. Provide GMP training where needed and review/disposition batch records when within EQ scope. - Drive periodic Quality Systems reviews at CMOs and support audits through GEMBA activities, root-cause analysis, and development of remediation actions. - Evaluate the effectiveness of CMO Quality Units and influence implementation of strong, self-sufficient quality systems. Escalate significant cGMP or compliance issues per internal procedures and support regulatory engagement and intelligence distribution. - Actively participate in External Manufacturing Quality Review Meetings, identifying issues and recommending continuous improvement actions. - Review and support responses to CMO regulatory inspections related to GSK products, assessing impact and suitability of responses prior to agency submission. - Work with suppliers to establish effective CAPAs tied to GSK audit observations, ensure timely closure, and coordinate Quality Alerts, Quality Plans, and continuous improvement activities. Support or lead internal audits as required. - Support technical and quality assessments for new product introductions, including review/approval of documentation (e.g., PTDs, PIFs) and defining quality requirements for tech transfers, validations, lab methods, stability protocols, SOPs, specs, and master batch records. - Support or execute timely disposition of finished product from CMOs to meet supply demands. - Where applicable, oversee quality relationships with third parties, manage medical device-related quality activities, release materials manufactured by CMOs, and lead/support GSK quality initiatives and projects. Why You: Basic qualifications: - Bachelor's degree in science with experience in pharmaceutical manufacturing and quality operations. - Experience applying cGMP requirements and working with pharmaceutical analytical methods and manufacturing processes. - Experience in Technical Quality and Operational Quality roles within the pharmaceutical industry. - Experience with Lean six Sigma or operational excellence/lean manufacturing systems experience Preferred Qualifications: - Experience applying quality systems principles and quality/risk‑management tools. - Experience making data‑driven decisions using risk‑management methodologies. - Technical knowledge across multiple pharmaceutical dosage forms. - Experience performing statistical analysis and data trending. - Good communication skills, including preparing and delivering clear presentations, with proficiency in written and spoken English. - Effective stakeholder‑management and negotiation experience. - Strong problem‑solving capability and experience managing multiple priorities. - Experience partnering with external organizations and understanding commercial considerations. - Ability to anticipate issues, work under uncertainty, and manage evolving work demands. - Experience in interpreting and implementing cGMPs, regulatory guidelines, and industry standards within operational environments. - Experience in managing Change Management processes, including execution and documentation of quality‑related changes. - Experience in supporting workstreams that involve regional or global collaboration. - Project Management experience, including coordination of cross‑functional activities, timelines, and deliverables. - Bilingual in Spanish or Portuguese Arrangements: The role is hybrid, requiring on-site work 2 to 3 days per week. Remote or fully home-working arrangements are not available for this role. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Title: Associate Director - Drug Product Focus Location: Collegeville United States Job Description: At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Position Summary You will lead sterile process engineering activities to support development and commercial supply of sterile drug products. You will work across formulation, analytics, manufacturing and external partners to design, scale and transfer robust sterile processes. We value clear problem solvers who build strong working relationships. This role offers technical growth, broad impact on patient-focused products, and the chance to work with experienced teams who unite science, technology and talent to get ahead of disease together. Key responsibilities include: - Work as drug product (DP) process engineering and analytics (PE&A) lead in a multi-disciplinary development team, liaising efficiently with Formulators, Modellers, Process Analytical Technology (PAT) Scientists, automation experts, data scientists and device engineers, to deliver the work packages required to understand DP unit operations and scale these-up effectively. - Provide expertise in process development, characterization, scale -up, technology transfer, and modelling, to deliver processes for sterile products (small molecule suspensions, ADC or Biopharm drug product) that are well understood. - Identify use‑cases where in silico tools can speed up DP development, then work with modelling and development teams to design, validate and deploy those solutions. Actively participate in technical reviews on projects, lead the technical transfer of processes, prepare functional project plans, and ensure timely execution. - Contribute to CMC team planning and objective setting, agreeing priorities and coordinating PE&A activities that support delivery of objectives. - Ensure proper Process Engineering decisions are taken at appropriate milestones within the DP project plan to accelerate early phase formulation and process design and minimize number of DOEs for scalability assessments and API consumption throughout the DP development life-cycle. - Author sections of regulatory documents relevant to Process Engineering platforms (IND / IMPD submissions, marketing applications, CMC briefing etc.). - Make innovative contributions to the department by leading platform development workstreams to assess, develop and implement new manufacturing platforms and establishing control strategies for DP processes. - Be accountable for platform robustness across the portfolio. - The job holder may act as an expert in specific unit operations. As such, they will be expected to master a body of knowledge for that unit operation and use this to act as the functional expert in the department. - This expertise will be focused on platform and process primarily within the sterile injectables portfolio. - Be technically persuasive both within GSK, for example, at project governance, with peers in other departments, or externally, with the academic community. - Ensure appropriate scientific review is in place throughout development and prior to key Project milestones. - Prepare and deliver Process Engineering and Analytics-relevant sections of technical and governance presentations and respond to resulting questions. Identify and escalate Process Engineering and Analytics-related risks at scientific reviews and through governance processes. Establishing control strategy for biopharm drug product manufacturing. - Ability to lead collaboratively in a matrix style environment - Enable sound decisions by your influence in matrix teams and technical governance, through depth of technical knowledge and effective communication, to collaborate actively with R&D Pilot Plants and Global Supply Chain manufacturing sites. - Deliver the above in a precise and timely manner, adhering to safety and quality expectations. Comply with the requirements of Quality, Safety and GSK policies and procedures and ensure that GSK intellectual property is protected. Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: - Bachelor of Science and/or engineering with 10+ years of experience - Experience with aseptic processing, sterile filtration, filling/stoppering operations, and lyophilization processes. - Experience evaluating, developing, and qualifying DP manufacturing equipment - Experience of data integrity principles, mentoring/developing staff in proper scientific study design, execution, and report writing Preferred Qualifications: If you have the following characteristics, it would be a plus: - PhD or Master of Science with significant experience in technical leadership, leading matrix team and team with direct reports - Authoring (or co-authoring) of publication(s) in peer-reviewed scientific journals - Lean Six Sigma (Green Belt or Black Belt) - Project Management Certification (PMP or CAPM) - ISPE Training Certificates - Professional Engineer (PE) License Working Arrangement This role is hybrid. You will be expected to be on-site regularly to lead experimental and transfer activities, with flexibility for remote work as needed. What we offer you You will join a team focused on meaningful impact. You will grow your technical and leadership skills. You will help create processes that enable safe, effective medicines to reach patients.

Site Name: Brazil - Rio de Janeiro, Home Worker - BRA (Sao Paulo) Posted Date: Apr 22 2026 Nossa estratégia Ahead Together está centrada na intervenção precoce para prevenir e alterar o curso das doenças, protegendo as pessoas e apoiando os sistemas de saúde. Nosso portfólio diversificado reúne vacinas, medicamentos especializados e medicamentos de uso geral. Por meio de inovação contínua e forte foco em excelência científica e técnica, buscamos desenvolver e lançar tratamentos que respondam aos principais desafios de saúde. A GSK segue comprometida com ambições comerciais relevantes para o futuro e, até 2031, temos como objetivo alcançar £40 bilhões em vendas anuais, ampliando nosso impacto positivo na saúde de bilhões de pacientes ao redor do mundo. A posição de gerente de pipeline e projetos estratégicos terá alta visibilidade e impacto estratégico, com atuação cross‑functional e participação em comitês executivos de governança. O escopo principal dessa posição é de preparar a GSK Brasil para lançamento de futuros produtos e indicações seguindo a estratégia global da GSK, e de garantir uma excelência de planejamento para maximizar o impacto desses lançamentos no mercado Brasileiro. O gerente liderará a governança da estratégia de pipeline, conduzindo iniciativas de transformação operacional do portfólio, assegurando priorização baseada em evidências, conformidade regulatória, estratégia de preço e readiness para pré‑launch. Será responsável por elaborar e validar business cases de alto impacto que transformem avanços científicos em soluções de alto impacto para nossos pacientes e clientes. Atuará continuamente com Marketing, Medical Affairs, Market Access, Government Affairs, Finanças e equipes regionais/globais para viabilizar decisões ágeis, alinhamento orçamentário e entrega de resultados mensuráveis. Posição baseada em Jacarepaguá/RJ ou São Paulo/SP. Suas Responsabilidades: Esse cargo dá a VOCÊ a oportunidade de liderar atividades chaves para progredir na SUA carreira. A principais responsabilidades são: - Desenvolver estratégia de pipeline e business cases, alinhando prioridades ao objetivo comercial e às dinâmicas de mercado. - Conduzir análises de mercado e inteligência competitiva para identificar oportunidades, riscos e barreiras. - Mapear a jornada do paciente por área terapêutica e quantificar o potencial de pacientes para suportar priorização e planejamento. - Definir posicionamento e proposta de valor dos produtos, assegurando diferenciação competitiva e alinhamento com insights de field medical. - Identificar gaps de mercado e orquestrar ações antecipadas com equipes cross-funcionais (Marketing, Vendas, Medical Affairs, Market Access, Government Affairs). - Liderar planejamento de pré-lançamento/readiness, garantindo governança, conformidade regulatória/ética e coordenação com equipes regionais/globais. Por que VOCÊ? Suas qualificações:  Estamos a procura de pessoas/profissionais com essas características para alcançar nossos objetivos: - Graduação Superior Completa; MBA ou pós graduação será diferencial. - Experiência sólida em comercialização farmacêutica, incluindo análise de mercado, pricing, reembolso, estratégias de acesso e experiência em lançamentos de produtos e/ou pipeline. - Autonomia e capacidade de organizar e conduzir projetos do zero, garantindo entrega de marcos no prazo e com qualidade. - Liderança e habilidade de influenciar equipes cross funcionais; experiência em ambiente multinacional (desejável); alinhamento com os valores da GSK (integridade, inovação e foco no paciente). - Agilidade para se adaptar a situações ambíguas, mudanças de objetivos, e dados parciais. - Fluência em português e inglês, com excelentes habilidades de comunicação e apresentação para públicos diversos. #LI-Remote Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require any adjustments or accommodation during the selection process to better showcase your abilities, please let our team know as soon as we contact you. We're here to support you. When applying, you may also choose to provide personal information, which helps us ensure a more inclusive selection process. Rest assured, your information will be treated with the utmost confidentiality and will not be accessible to hiring managers. Let’s keep maintaining an inclusive and welcoming workplace. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Find more about life at GSK at www.gsk.com

Site Name: USA - Georgia - Atlanta East Posted Date: Apr 22 2026 Territory to Include, but not limited to, Atlanta East, GA At GSK, we have already delivered unprecedented change over the past four years, improving R&D, strengthening our leadership, and transforming our commercial execution. We have a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and genetics science. GSK’s ambition and purpose is to unite science, talent and technology to get ahead of disease together – all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; and as a new GSK where outstanding people thrive.​ Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culture that is ambitious for patients – so we deliver what matters better and faster; accountable for impact – with clear ownership of goals and support to succeed; and where we do the right thing. So, if you’re ready to improve the lives of billions, join us at this exciting moment in our journey. Join our challenge to get Ahead Together Why US Respiratory Sales? The US Respiratory sales force has a strong track record of bringing industry leading products within primary care to market. As an industry leader in Primary Care, we harness the talent of our people, combined with our proven and unique capabilities to drive growth and performance to impact the lives of COPD and asthma patients in the US. Our ambition is to impact the lives of 3.5 million patients by 2024. We take pride in recruiting and retaining talent by offering multiple development opportunities within the Business Unit, combined with a transparent talent management approach aligned to the individual’s opportunities and aspirations Our business unit embodies being ambitious for patients, accountable for impact, and doing the right thing. We believe that to be successful, our people should thrive. The GSK Sales Professional is accountable for convincing high potential physicians and allied health professionals in independent offices, physician groups and hospital systems to prescribe GSK products instead of competitive products for disease states and patients in face to face selling in accordance with product indications and prescribing information. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: - Drive territory sales performance increasing product market share/volumes of promoted COPD/Asthma products through impactful selling interactions with specific customer segments. - Take complete ownership and accountability over actions and activity levels aligned to GSK strategy - Acquire and maintain knowledge of market, GSK products and competitive products for competitive selling - Proactively analyzes sales data and develops territory business plans to consistently grow business - Collaborates with territory team members to develop dynamic routing and call schedules to support sales plans. - Develop and maintain strong working relationships with Marketing, Payer Relations Managers, Medical (MSLs), and other functions within GSK - Proactively resource reach and frequency activities, in-services, and educational programs - Complete all administrative requirements associated with role in an accurate and timely manner; distributing and tracking FDA regulated product samples, daily call recording, completion of required role-related eLearning modules, regular customer maintenance and expenses - Adhere to and follow GSK policies, practices, risk-adverse standards and values in support of our customers, patients, fellow employees, and individual expectations Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: - Minimum 2 years demonstrated sales experience with successful track record of exceeding expectations - Bachelor’s or master's degree - Ability to travel domestically as necessary, which may include overnight and/or weekend travel. The amount will depend on the specific territory size. - Valid Driver’s License - Must be able to drive or operate a vehicle as driving is an essential function of this role. - Proficiency with Microsoft Word, PowerPoint, Excel and Outlook and familiarity with CRM software Preferred Qualifications: The following characteristics it would be a plus: - Preferred experience in healthcare related sales, specifically respiratory and allergy - Familiarity with; Managed Care Plans, Insurance Formularies, Retail Pharmacies (understanding prescription processing, prior authorizations etc.) - Strong communication, presentation and influencing skills - Demonstrated ability to identify unique sales opportunities and to perform tasks beyond designated responsibilities. - Strong business planning skills and ability to multi-task. - Can work independently with strong attention to detail Demonstrated Capabilities: - Winning Mindset. Do you have the passion and focus to continuously shift performance from good, to better, to best? Are you a top performer that opens doors, gets on calendars, gains support and wins the business? - Ambitious Goals. Do you make goals that stretch you? Do you pursue them with intensity and pace? Are you in control having a plan for yourself, and regularly evaluate where you want to be, where you are, and what the gap is? - Courageous. Do you speak-up and challenge in the spirit of curiosity and developing the business? Are you resilient and courageous to bounce back from setbacks, overcome barriers and get back on track? - Change maker. Do you push yourself /others for change/action in the best interest of everyone and the business? - Improvement Mindset. Do you continuously seek and apply feedback to learn and grow yourself and the business? - Accountable. Do you hold yourself and others accountable to commitments? Do you own your decisions? - Inspiration. Do you align, connect and inspire your teammates? - Communicate with influence. Do you have masterful conversations which influence people with speed and clarity? #GSKCommercial #LI-REMOTE Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

GSK hat ehrgeizige kommerzielle Ziele für die Zukunft. Bis 2031 wollen wir einen Umsatz von £38 Milliarden jährlich erzielen – basierend auf dem bestehenden starken Leistungstrend, der den positiven Einfluss, den wir auf die Gesundheit von Milliarden von Patienten weltweit haben können, erheblich steigern wird. Unsere Strategie „Ahead Together“ bedeutet, frühzeitig einzugreifen, um Krankheiten zu verhindern und ihren Verlauf zu verändern, um Menschen zu schützen und die Gesundheitssysteme zu unterstützen. Unser Portfolio besteht aus Impfstoffen, Spezialmedikamenten und Allgemeinmedikamenten. Dies sind die drei verschiedenen Arten von Produkten, die wir entwickeln, um Krankheiten zu verhindern und zu behandeln, viele davon mit dem Potenzial, die Ersten oder Besten ihrer Art zu sein. Pharmaberater*in Impfstoffe (m/w/d) - Bautzen, Görlitz, Zittau, Hoyerswerda Als Pharmaberater sind Sie verantwortlich für die Sicherstellung und optimale Patientenversorgung bei den zugeordneten Kundengruppen sowie bestmöglichen Platzierung und Klarstellung des Nutzens unserer GSK-Produkte. Hauptaufgaben - Umsatz- und Ergebnisverantwortung für die betreuten Produkte im Gebiet - Gebietsmanagement auf Basis etablierter Prozesse (z.B. Erstellung eines gebietsspezifischen Maßnahmenplanes, Analyse der Umsatz-/Absatzentwicklung und Ableitung korrespondierender Maßnahmen unter Nutzung der vorhandenen EDV- und Analyseinstrumente, RMB-Verantwortung, Besuchsplanung), systematische Erfolgskontrolle - Information der Kundengruppen über Produktanwendungen und -nutzen - Planung, Organisation und Durchführung von Veranstaltungen wie der Fortbildung von Ärzten, Pflege- oder Praxispersonal oder sonstigen relevanten Zielgruppen im Rahmen der GSK-Vorgaben - Gebietsübergreifende Kooperation mit Kolleg*innen und anderen Funktionsbereichen nach Bedarf Qualifikationen & Fähigkeiten - Qualifikation nach § 75 AMG oder einschlägiger Hochschulabschluss - Kenntnisse über Vertriebswege und kaufmännische Rahmenbedingungen im niedergelassenen Bereich (z.B. Rabattsysteme, Preisgestaltung, gesetzliche Vorgaben) - Verkaufs- und Kundenorientierung, Verbindlichkeit gegenüber den Kunden - Vertretung der GSK Richtlinien und des Kodex - Ethischer Anspruch an die eigene Person sowie das Unternehmen - Fließende Deutschkenntnisse Bevorzugte Qualifikationen & Fähigkeiten - Erfahrung im pharmazeutischen Vertrieb Weitere Informationen: Annual Report 2023 Product Pipeline #EBDE #LI-GSK #LI-Remote Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at DE.Contact-Recruitment@gsk.com where you can also request a call. Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to ethnicity, colour, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Director, Clinical Pharmacology The Department of Clinical Pharmacology Modelling & Simulation Respiratory and Inflammation (CPMS R&I) at GSK is recruiting a director-level Clinical Pharmacologist. This role is based in UK or US, with remote working or placement at other European GSK sites possible for the right candidate. Job Purpose: The Director, Clinical Pharmacology sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation, which aims to be a centre of excellence in Model‑Informed Drug Development (MIDD) by integrating clinical pharmacology, digital medicine, translational imaging and mechanistic/systems modelling. You will lead the end‑to‑end application of MIDD across the drug development lifecycle—from first‑in‑human studies through filing and lifecycle management—and provide clinical pharmacology strategy and evidence‑generation input. This is an opportunity to join a highly regarded, high‑impact team with a strong publication track record, reporting directly to the Respiratory, Immunology & Inflammation Research Unit (RIIRU). Main responsibilities: - Design & Execute Model Informed and Clinical Pharmacology strategies: Develop and implement robust MIDD & ClinPharm evidence strategies to de risk and accelerate RIIRU programs. Aim for faster development, optimal dosing and stronger regulatory positioning across respiratory, inflammation, neurodegeneration and emerging areas — and support business development opportunities. - Ensure robust ways of working and regulatory ready evidence Draft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling. Maintain up to date knowledge of FDA, EMA, CDE, PMDA and ICH expectations and embed regulatory considerations and best practices into study design and MIDD strategies. - Build cross‑functional partnerships Work closely with CPQM peers (digital medicine, translational imaging, MIDD specialists, mechanistic/systems modelling) and cross functional partners (biology, data science, computational biology, clinical, etc.). Maintain strong networks and share best practices in the CPMS community of practice. Build strong network key functions such as AI/ML, biomarkers, biostatistics, clinical operations, data science, computational biology and RWE to embed quantitative approaches into decision making at asset level. - External engagement & scientific leadership Raise GSK’s profile in MIDD, clinical pharmacology, QSP and AI/ML integration through publications, conference presentations and active participation in scientific and regulatory fora to influence method adoption and regulatory dialogue Why you? Basic Qualifications: - PhD in life sciences or related discipline, MD, or PharmD, with experience in clinical pharmacology, modelling and simulation in pharmaceutical research and development. - Significant experience in clinical pharmacology, modelling/simulation and drug development to solve practical problems in the pharmaceutical industry. - Experience in pharmacometrics and their application to clinical questions in drug development. Preferred Qualifications: - Additional experience in respiratory and immunology would be beneficial. - Demonstrated experience of collaboration in a multi-discipline team, using effective communication and taking personal accountability for timely delivery of results. - Evidenced experience making sound judgement in complex situations and adapting to changing business needs by prioritizing multiple tasks. - Experience working with senior stakeholders in a cross functional environment. - Track record of implementation of Model-Informed Drug Discovery and Development (MIDD) approaches to accelerate patient access to novel therapies and to expand therapeutic indications of marketed drugs. - Drive and learning agility to build knowledge on a drug-disease system, symptom progression, standard of care, and trial design. *LI-GSK# • If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $188,100 to $313,500. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the Link where you will find answers to multiple questions we receive Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Site Name: UK - Hertfordshire - Stevenage Posted Date: Apr 22 2026 Director, Clinical Pharmacology The Department of Clinical Pharmacology Modelling & Simulation Respiratory and Inflammation (CPMS R&I) at GSK is recruiting a director-level Clinical Pharmacologist. This role is based in UK or US, with remote working or placement at other European GSK sites possible for the right candidate. Job Purpose: The Director, Clinical Pharmacology sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation, which aims to be a centre of excellence in Model‑Informed Drug Development (MIDD) by integrating clinical pharmacology, digital medicine, translational imaging and mechanistic/systems modelling. You will lead the end‑to‑end application of MIDD across the drug development lifecycle—from first‑in‑human studies through filing and lifecycle management—and provide clinical pharmacology strategy and evidence‑generation input. This is an opportunity to join a highly regarded, high‑impact team with a strong publication track record, reporting directly to the Respiratory, Immunology & Inflammation Research Unit (RIIRU). Main responsibilities: - Design & Execute Model Informed and Clinical Pharmacology strategies: Develop and implement robust MIDD & ClinPharm evidence strategies to de risk and accelerate RIIRU programs. Aim for faster development, optimal dosing and stronger regulatory positioning across respiratory, inflammation, neurodegeneration and emerging areas — and support business development opportunities. - Ensure robust ways of working and regulatory ready evidence Draft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling. Maintain up to date knowledge of FDA, EMA, CDE, PMDA and ICH expectations and embed regulatory considerations and best practices into study design and MIDD strategies. - Build cross‑functional partnerships Work closely with CPQM peers (digital medicine, translational imaging, MIDD specialists, mechanistic/systems modelling) and cross functional partners (biology, data science, computational biology, clinical, etc.). Maintain strong networks and share best practices in the CPMS community of practice. Build strong network key functions such as AI/ML, biomarkers, biostatistics, clinical operations, data science, computational biology and RWE to embed quantitative approaches into decision making at asset level. - External engagement & scientific leadership Raise GSK’s profile in MIDD, clinical pharmacology, QSP and AI/ML integration through publications, conference presentations and active participation in scientific and regulatory fora to influence method adoption and regulatory dialogue Why you? Basic Qualifications: - PhD in life sciences or related discipline, MD, or PharmD, with experience in clinical pharmacology, modelling and simulation in pharmaceutical research and development. - Significant experience in clinical pharmacology, modelling/simulation and drug development to solve practical problems in the pharmaceutical industry. - Experience in pharmacometrics and their application to clinical questions in drug development. Preferred Qualifications: - Additional experience in respiratory and immunology would be beneficial. - Demonstrated experience of collaboration in a multi-discipline team, using effective communication and taking personal accountability for timely delivery of results. - Evidenced experience making sound judgement in complex situations and adapting to changing business needs by prioritizing multiple tasks. - Experience working with senior stakeholders in a cross functional environment. - Track record of implementation of Model-Informed Drug Discovery and Development (MIDD) approaches to accelerate patient access to novel therapies and to expand therapeutic indications of marketed drugs. - Drive and learning agility to build knowledge on a drug-disease system, symptom progression, standard of care, and trial design. *LI-GSK# • If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $188,100 to $313,500. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the Link where you will find answers to multiple questions we receive Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/