• Responsible for the development of the defined programs strategic business case - covering all projects or programs within execution and delivery scope. • Responsible for the definition and the fulfillment of benefits, objectives, and the realization of success criteria - aligned to the approved strategic business case. • Responsible for gathering and recording of the execution and delivery scope requirements - documented in an overall program charter or execution plan. • Responsible for documenting lean, established methods, processes and procedures are used for managing projects and programs throughout a life cycle, seeing them through to implementation. • Responsible to produce and maintain the overall program framework / playbook – the document is inclusive of the program execution plan and delivery methodology. • Responsible for maintaining tools and templates aligned to the agreed program execution plan and delivery methodology. • Responsible for identifying strategic portfolio and program stakeholders, maintaining communication, influencing stakeholder involvement, and obtaining input as required. • Responsible for analyzing program risk and opportunities trend and their respective cost and schedule impact. • Responsible for defining an overall approach to continuous improvements incorporating strategic objectives and alignment with defined benefits and targets. • Support the day-to-day operational management duties of the team, as part of the leadership team you will be required to support the achievement of our strategic goals. • Act as or support the commission leads on our programs including managing client relations and commercial contractual arrangements. • Support the development of program processes and systems that enable efficient data collection, management, and benchmarking. • Ensure compliance to company compliance rules on all projects managed by third party Project Managers. • Design and undertake training sessions and produce materials on new processes, changes and efficiencies. • Prepare monthly and ad hoc reports on governance performance for a variety of audiences. • Champion service quality in everything we do. • Lead and motivate others to deliver excellent client service. • Support business development activities with new and existing clients, including bid writing. • Act as the key, day-to-day client interface, ensuring that client objectives are met through the delivery of our service. • Coach and mentor staff, assisting them to achieve professional designations and career growth objectives. • Understanding, identifying, and developing cross-divisional ideas into value opportunities.

Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation. Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs. Description of Role Centessa is seeking a Director of Program Management within the CMC group. The CMC PM will provide leadership and operational support to the development and manufacturing of our small molecule programs and actively engage with internal teams and external contract manufacturing organizations. Reporting to the Vice President, CMC, this individual will drive effective execution of CMC deliverables by the project teams in coordination with and support of program and corporate goals. The ideal candidate should be highly organized and an exceptional communicator with experience leading early phase pre-IND teams through late-stage CMC Registration/Commercial validation and launch activities. Travel to vendors both domestically and internationally will be required. Key Responsibilities - Serve as the main point of contact for all CMC project-related communications especially focused on drug product development, manufacturing, release, packaging, labeling, and stability coordination - Foster strong relationships with internal teams, and external partners including CDMOs. - Participate in regular telecon meetings with CDMOs to maintain the business relationship, progress, meeting notes and action items. - Monitor timelines and contracts for accuracy and follow up on any discrepancies with contractors and/or internal personnel. - Support CMC activities including tracking relevant GMP and Regulatory documentation. - Interfaces with drug substance, drug product, analytical, non-clinical, clinical, Regulatory, supply chain, and Quality colleagues to ensure all projects are delivered on time, within scope and budget. - Work with CMC team members to identify resource constraints, risks, and conflicts that could impact the team’s bandwidth and/or company timelines. - Cover all other project management requirements including shipment/logistics coordination, inventory, and production planning. - Drive the development and management of detailed and integrated development plans for CMC projects that account for all phases of drug development across functions with timelines, work plans including interdependencies, gating items, budget, and risk management strategies. - Oversee the delivery of project objectives per the program strategy, with a strong focus on meeting critical milestones, and managing scope changes while integrating project constraints. - Facilitate effective collaboration across CMC functional teams, ensuring alignment on project goals and priorities. - Communicate project updates consistently to various stakeholders, about strategy, adjustments, and development progress. - Experience utilizing project management tools and best practices to support CMC activities. - Excellent attention to detail, communication, time management, organizational skills, and flexible attitude to work assignments and new learning with proven ability to interact in a team environment. - Comfortable in a fast-paced small company environment with the ability to manage a variety of projects simultaneously and handle rapidly changing information. - Project management professional (PMP) certification preferred. - Expert MS Office skills including Excel, PowerPoint, MS Project, and other PM timeline software (e.g. Smartsheet). Qualifications - Bachelor's degree in scientific or related field; advanced degree in a scientific discipline preferred. - 10+ years of pharmaceutical industry experience, including 7+ years leading CMC project/program management activities - Proven experience in small molecule drug development, with emphasis on drug product development and manufacturing - Strong understanding of the end-to-end drug development process, including CMC, non-clinical, clinical, and regulatory activities - Demonstrated knowledge of CMC requirements across all phases of clinical development - Thorough understanding of cGMP regulations for pharmaceutical products - Experience coordinating and managing CDMO activities supporting development and commercialization - Strong project management, organizational, and prioritization skills to manage multiple, evolving programs - Excellent decision-making, analytical, and resource management skills in dynamic, global environments - Effective communicator with the ability to clearly convey complex scientific information both verbally and in writing - Ability to work independently while collaborating cross-functionally and with stakeholders at all organizational levels - Self-motivated, results-driven, adaptable to changing priorities, and willing to travel domestically and internationally Compensation The annual base salary range for this position is $185,000.00 to $240,000.00. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, and job knowledge. In addition to base pay, this role is eligible for a discretionary annual bonus and participation in our equity program, allowing you to share in Centessa’s long-term success. Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program. Work Location The Director CMC Program Management role is a remote role based in the US, with domestic and international travel. POSITION: Full-Time, Exempt EEOC Statement: Centessa Pharmaceuticals believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Centessa Pharmaceuticals will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.

Lumen is the trusted network for AI. We’re transforming how businesses connect, secure, and scale in an AI-driven world. By connecting people, data, and applications quickly, securely, and effortlessly, we help organizations move faster and unlock what’s next. At Lumen, people power progress. Our culture is built on teamwork, trust, and transparency, giving you the flexibility, support, and opportunity to make a lasting impact. We’re looking for top-tier talent ready to take on the challenge. Join us in building the future. The Role The Program Manager, Modernization & Simplification (M&S) Coach partners with leaders and cross functional teams to drive execution rigor, accountability, and measurable business outcomes across enterprise transformation initiatives. This role is not a traditional project management position. Instead, it focuses on coaching leaders and teams for effective execution, strengthening business and financial discipline, and ensuring initiatives translate strategy into results. The M&S Coach operates as a trusted advisor and execution partner, helping leaders clarify priorities, navigate complexity, and drive progress through influence, strong business acumen, and executivelevel communication. Work Location This is a work from home position within the U.S. The Main Responsibilities - Coach initiative owners and workstream leaders to strengthen execution discipline, ownership, and followthrough on commitments - Reinforce accountability for outcomes by setting clear expectations, reviewing progress, and challenging plans and assumptions when needed - Develop and lead executivelevel presentations that clearly communicate progress, risks, tradeoffs, and decisions required - Plan and facilitate executive and crossfunctional meetings, ensuring discussions are focused, decisions are clear, and actions are owned - Apply strong business and financial acumen to evaluate initiative readiness, value assumptions, execution risks, and tradeoffs - Partner with Finance and business leaders to ensure initiatives are grounded in sound business cases and realistic value delivery plans - Identify execution gaps, decision bottlenecks, and crossfunctional dependencies; work with leaders to resolve issues and maintain momentum - Influence and align stakeholders across Product, Technology, Operations, Finance, Marketing, and other functions around shared priorities - Promote consistent ways of working, transparency, and outcomefocused execution across the M&S portfolio What We Look For in a Candidate Required Qualifications: - Bachelor’s degree in Business, Finance, Operations, or a related field - 5–7 years of experience in transformation, strategy execution, operations, consulting, or similar roles - Demonstrated ability to influence leaders and teams without direct authority - Strong executive communication skills, including experience creating leadershipready presentations and leading seniorlevel discussions - Proven business acumen with the ability to assess value, risk, and execution tradeoffs - Experience working in complex, fastpaced, and highly matrixed environments Preferred Qualifications: - Experience supporting enterprisescale transformation, modernization, or costreduction efforts - Comfort partnering closely with Finance on business cases, value tracking, or financial tradeoff discussions - Experience in technology, telecommunications, or large enterprise environments Key Attributes - Execution focused coach with strong business judgment - Confident executive presence and clear, concise communicator - Comfortable challenging leaders constructively to improve outcomes - Collaborative, adaptable, and outcomeoriented Compensation This information reflects the anticipated base salary range for this position based on current national data. Minimums and maximums may vary based on location. Individual pay is based on skills, experience and other relevant factors. Location Based Pay Ranges: $103,711 - $138,281 in these states: AL, AR, AZ, FL, GA, IA, ID, IN, KS, KY, LA, ME, MO, MS, MT, ND, NE, NM, OH, OK, PA, SC, SD, TN, UT, VT, WI, WV, and WY. $108,896 - $145,195 in these states: CO, HI, MI, MN, NC, NH, NV, OR, and RI. $114,082 - $152,109 in these states: AK, CA, CT, DC, DE, IL, MA, MD, NJ, NY, TX, VA, and WA. Lumen offers a comprehensive package featuring a broad range of Health, Life, Voluntary Lifestyle benefits and other perks that enhance your physical, mental, emotional and financial wellbeing. We're able to answer any additional questions you may have about our bonus structure (short-term incentives, long-term incentives and/or sales compensation) as you move through the selection process. Learn more about Lumen's: - Benefits - Bonus Structure #LI-Remote #LI-HR1 Requisition #: 341749 Background Screening If you are selected for a position, there will be a background screen, which may include checks for criminal records and/or motor vehicle reports and/or drug screening, depending on the position requirements. For more information on these checks, please refer to the Post Offer section of our FAQ page. Job-related concerns identified during the background screening may disqualify you from the new position or your current role. Background results will be evaluated on a case-by-case basis. Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Equal Employment Opportunities We are committed to providing equal employment opportunities to all persons regardless of race, color, ancestry, citizenship, national origin, religion, veteran status, disability, genetic characteristic or information, age, gender, sexual orientation, gender identity, gender expression, marital status, family status, pregnancy, or other legally protected status (collectively, “protected statuses”). We do not tolerate unlawful discrimination in any employment decisions, including recruiting, hiring, compensation, promotion, benefits, discipline, termination, job assignments or training. Privacy Notice Lumen is committed to protecting the privacy and security of personal information collected during the recruitment and hiring process. Our Privacy Notice explains how we collect, use, disclose, and protect applicant information, as well as how individuals may request access to or deletion of their personal data. To review Lumen’s Privacy Notice, please visit: https://jobs.lumen.com/global/en/privacy-notice Disclaimer The job responsibilities described above indicate the general nature and level of work performed by employees within this classification. It is not intended to include a comprehensive inventory of all duties and responsibilities for this job. Job duties and responsibilities are subject to change based on evolving business needs and conditions. In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Please be advised that Lumen does not require any form of payment from job applicants during the recruitment process. All legitimate job openings will be posted on our official website or communicated through official company email addresses. If you encounter any job offers that request payment in exchange for employment at Lumen, they are not for employment with us, but may relate to another company with a similar name.

• Manage end-to-end project schedules for customer engagements across Applied AI (FDE team) and core engineering teams spanning multiple geographies and time zones • Maintain real-time project status visibility — Confluence boards, Jira tracking, weekly status reports — so leadership, engineering, and the Delivery Manager always have a single source of truth • Run internal project review cadences: bi-weekly planning reviews, customer submissions reviews, and dev question sessions across all active engagements • Proactively identify risks, dependencies, and blockers before they become surprises — escalate to the Delivery Manager with proposed mitigations, not after deadlines slip • Own cross-site coordination across multiple sites — bridging time zones, aligning handoffs, and ensuring nothing falls between teams • Drive daily and weekly status updates across all active projects — post EOD updates in team channels with key changes, blockers, and next actions tagged to DRIs • Prepare and deliver weekly internal status reports to the CPO every Friday — consolidating project health, risk register, and upcoming milestones across all accounts • Track and maintain delivery governance artifacts: project plans, feedback/release trackers, QA checklists, go-live readiness assessments • Coordinate resource allocation and capacity planning across FDEs and engineering — flag overload risks and propose reallocation before quality suffers • Ensure Jira hygiene: correct assignees, updated due dates, closed tickets, and clean backlogs — so automated reporting and AI tools produce accurate outputs • Support the Delivery Manager in preparing customer-facing materials: milestone review decks, progress summaries, and QBR data