Director, Program Management, CMC
Location
United States
Posted
76 days ago
Salary
$185K - $240K / year
Seniority
Lead
No structured requirement data.
Job Description
Director, Program Management, CMC
Centessa Pharmaceuticals, LLC
Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation. Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs. Description of Role Centessa is seeking a Director of Program Management within the CMC group. The CMC PM will provide leadership and operational support to the development and manufacturing of our small molecule programs and actively engage with internal teams and external contract manufacturing organizations. Reporting to the Vice President, CMC, this individual will drive effective execution of CMC deliverables by the project teams in coordination with and support of program and corporate goals. The ideal candidate should be highly organized and an exceptional communicator with experience leading early phase pre-IND teams through late-stage CMC Registration/Commercial validation and launch activities. Travel to vendors both domestically and internationally will be required. Key Responsibilities - Serve as the main point of contact for all CMC project-related communications especially focused on drug product development, manufacturing, release, packaging, labeling, and stability coordination - Foster strong relationships with internal teams, and external partners including CDMOs. - Participate in regular telecon meetings with CDMOs to maintain the business relationship, progress, meeting notes and action items. - Monitor timelines and contracts for accuracy and follow up on any discrepancies with contractors and/or internal personnel. - Support CMC activities including tracking relevant GMP and Regulatory documentation. - Interfaces with drug substance, drug product, analytical, non-clinical, clinical, Regulatory, supply chain, and Quality colleagues to ensure all projects are delivered on time, within scope and budget. - Work with CMC team members to identify resource constraints, risks, and conflicts that could impact the team’s bandwidth and/or company timelines. - Cover all other project management requirements including shipment/logistics coordination, inventory, and production planning. - Drive the development and management of detailed and integrated development plans for CMC projects that account for all phases of drug development across functions with timelines, work plans including interdependencies, gating items, budget, and risk management strategies. - Oversee the delivery of project objectives per the program strategy, with a strong focus on meeting critical milestones, and managing scope changes while integrating project constraints. - Facilitate effective collaboration across CMC functional teams, ensuring alignment on project goals and priorities. - Communicate project updates consistently to various stakeholders, about strategy, adjustments, and development progress. - Experience utilizing project management tools and best practices to support CMC activities. - Excellent attention to detail, communication, time management, organizational skills, and flexible attitude to work assignments and new learning with proven ability to interact in a team environment. - Comfortable in a fast-paced small company environment with the ability to manage a variety of projects simultaneously and handle rapidly changing information. - Project management professional (PMP) certification preferred. - Expert MS Office skills including Excel, PowerPoint, MS Project, and other PM timeline software (e.g. Smartsheet). Qualifications - Bachelor's degree in scientific or related field; advanced degree in a scientific discipline preferred. - 10+ years of pharmaceutical industry experience, including 7+ years leading CMC project/program management activities - Proven experience in small molecule drug development, with emphasis on drug product development and manufacturing - Strong understanding of the end-to-end drug development process, including CMC, non-clinical, clinical, and regulatory activities - Demonstrated knowledge of CMC requirements across all phases of clinical development - Thorough understanding of cGMP regulations for pharmaceutical products - Experience coordinating and managing CDMO activities supporting development and commercialization - Strong project management, organizational, and prioritization skills to manage multiple, evolving programs - Excellent decision-making, analytical, and resource management skills in dynamic, global environments - Effective communicator with the ability to clearly convey complex scientific information both verbally and in writing - Ability to work independently while collaborating cross-functionally and with stakeholders at all organizational levels - Self-motivated, results-driven, adaptable to changing priorities, and willing to travel domestically and internationally Compensation The annual base salary range for this position is $185,000.00 to $240,000.00. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, and job knowledge. In addition to base pay, this role is eligible for a discretionary annual bonus and participation in our equity program, allowing you to share in Centessa’s long-term success. Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program. Work Location The Director CMC Program Management role is a remote role based in the US, with domestic and international travel. POSITION: Full-Time, Exempt EEOC Statement: Centessa Pharmaceuticals believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Centessa Pharmaceuticals will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.
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2026 Summer Internship, TODAY Californian
USA TODAY Co.USA TODAY Co., Inc. is a diversified media company with expansive reach at the national and local level dedicated to empowering and enriching communities. We seek to inspire, inform, and connect audiences as a sustainable, growth-focused media and digital marketing solutions company. Through our trusted brands, including the USA TODAY NETWORK, we provide essential journalism, local content, and digital experiences to audiences and businesses.
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Senior Partner Manager – Hyperscalers & System Integrators
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All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. Our success is reliant on building teams that include people from different backgrounds and experiences who can elevate assumptions and ideas with fresh perspectives. We're dedicated to hiring the whole human, not just a resume. To that end, we look for a diverse pool of applicants-including those from historically marginalized groups. We would like to invite you to apply even if you don't think you meet all of the requirements listed below. We don't want a few lines in a job description to get between us and the opportunity to meet you.


