“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky” Mineralys is a fully remote company. Associate Director / Director Biostatistics The Associate Director / Director, Biostatistics will lead the full scope of statistical strategy and execution for clinical development programs at Mineralys. This individual is accountable for the design, analysis, and interpretation of clinical trials, as well as statistical contributions to regulatory submissions, including NDA readiness. Operating in a fast-paced, pre-commercial biotech environment, this role requires a strong balance of strategic thinking and operational oversight, with high visibility across Clinical, Medical, and Regulatory teams. Key Responsibilities - Lead the full scope of Biostatistics activities for assigned clinical programs or indications - Define and execute statistical strategies for clinical trials and regulatory submissions - Design clinical studies, including endpoints, estimands, and sample size calculations - Serve as statistical lead on Study Executive Teams and Clinical Development Teams - Provide quantitative input into clinical development plans, including Go/No-Go criteria and probability of technical success - Ensure quality and timely delivery of statistical outputs, including interim, final, and integrated analyses - Contribute to regulatory submissions (e.g., NDA) and represent Biostatistics in interactions with FDA - Collaborate cross-functionally with Clinical, Medical, and Regulatory - Oversee CROs and/or internal teams; ensure quality, timeliness, and compliance of deliverables - Collaborate with internal leaders of Statistical Programming and Data Management - Supervise statistical programmers for QC and validation activities - Interpret analysis results and ensure accuracy in study reports, publications, and regulatory documents - Contribute to abstracts, posters, and presentations for internal and external stakeholders - Drive continuous improvement initiatives within Biostatistics and cross-functional processes Qualifications - PhD in Biostatistics, Statistics, or related field with ~8+ years of industry experience OR MS with ~11+ years of experience in drug development - Pharmaceutical/biotech industry experience required - Demonstrated experience providing statistical leadership at study or program level - Strong experience designing clinical trials and collaborating with cross-functional teams - Experience supporting regulatory submissions (NDA/BLA) - Experience interacting with regulatory authorities preferred - Experience overseeing CROs or external vendors - Experience supervising programming deliverables or QC activities - Strong knowledge of CDISC standards, data structures, and statistical methodologies - Working knowledge of SAS and/or R (oversight level, not heavy programming) - Experience with outcomes research preferred - Therapeutic area experience flexible; preference for chronic diseases or larger patient populations Core Competencies - Strong understanding of clinical development processes and regulatory expectations - Ability to lead and influence in a matrixed environment - Excellent communication skills; able to translate statistical concepts to non-statistical audiences - Demonstrated ability to balance urgency with quality - Analytical rigor with a pragmatic, execution-oriented mindset - Experience applying innovative statistical methodologies Travel - This position requires up to 10% travel. Frequently travel is outside the local area and overnight. This position is eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level. US Salary Range: $200,000 - $230,000 #LI-Remote

About the job We are seeking an experienced and strategic Regional Director, Field Medical Affairs, to lead our East region. This newly created role will oversee a team of Medical Science Liaisons (MSLs) and serve as a key driver of scientific engagement, medical operations strategy, and cross-functional collaboration. The ideal candidate brings expertise in Eyecare, strong leadership experience within Medical Affairs, and a demonstrated ability to build meaningful relationships with Key Opinion Leaders (KOLs) and Eye Care Practitioners (ECPs). The role plays a critical part in advancing the organization’s medical strategy and supporting cross-functional collaboration across teams. The successful candidate will combine scientific acumen with strong leadership and strategic thinking, driving excellence in field medical execution while contributing to the broader goals of the Medical Affairs organization. Let’s talk about some of the key responsibilities of the role: Leadership & Team Management: - Lead, mentor, and manage a team of MSLs (N=6), fostering a collaborative, high-performing, and scientifically rigorous culture. - Set clear expectations on the development and execution of territory plans, objectives, and key performance indicators (KPIs) for each MSL. - Conduct regular performance evaluations, identify skill gaps, and support MSL development through coaching, training, and career growth opportunities. - Collaborate with the Medical Affairs Operations leadership team to align MSL activities with organizational priorities and strategic initiatives. Strategic Planning & Execution: - Serve as a disease state and product expert, providing strategic input into MSL educational initiatives and product launch planning. - Contribute to the development of Field Medical Strategy and Tactics in line with corporate and medical strategic goals. - Ensure MSLs are equipped with the latest scientific data and clinical information and support their integration into both regional and national-level initiatives. - Partner with Medical Affairs Strategy Leads to oversee the Medical Strategy Tactical Team (MSTT), ensuring medical affairs insights are synthesized and translated into actionable plans. - Collaborate with Field Medical Trainer and Medical Operations Leadership to develop and partake in field medical training and being a resource for our field team. - Support medical conference strategy and planning, attend conferences to provide scientific expertise and collaborate with ECPs. - Identify gaps in ECP education and clinical evidence; propose ideas on how to address unmet educational and evidence needs and collaborate with medical experts on disease state and product related education. Scientific Exchange & KOL Relationship Management: - Provide strategic oversight of MSL-led engagement with KOLs, ECPs, clinician scientists and researchers, and key stakeholders across the region to ensure consistent, high-quality scientific exchange. - Oversee team participation in scientific congresses, advisory boards, and other external engagements to strengthen relationships and advance scientific understanding. - Stay current on scientific literature and market and keep tabs on KOL engagement and opportunities for disease state education and awareness. Cross-Functional Collaboration: - Oversee team adherence to pharmacovigilance and safety requirements, ensuring accurate and timely adverse event reporting. - Compliantly partner with regional Sales leadership (RDLs) for field related needs and solutions. Compliance & Reporting: - Ensure all MSL activities comply with regulatory, ethical, and company standards, including GxP (Good Clinical Practice) and HIPAA regulations. - Provide regular updates to Medical Affairs VP and Operations on MSL team progress, KOL engagement, and key initiatives, incorporating metrics on impact and outcomes, as well as feedback, identified opportunities, and potential solutions. - Stay abreast of the competitive landscape and emerging trends in ophthalmology, ensuring MSL activities reflect the latest scientific advancements. Leadership Competencies - This role requires mastery of the Tarsus Leadership Competencies for Leading People, including: - Decision Making - Demonstrates strong decision-making by applying structured analysis to complex challenges, balancing competing priorities and long-term impacts while engaging stakeholders and driving solutions aligned with organizational goals. - Collaboration and Team Building - Promotes collaboration by aligning diverse teams around shared goals, fostering healthy debate to advance outcomes, and building strong networks that strengthen organizational effectiveness and cross-team learning. - Outcome Driven - Demonstrates strong outcomes focus by aligning teams around shared priorities, proactively addressing risks and dependencies, and driving cross-functional accountability to sustain progress and deliver results. - Empowering Others - Fosters empowerment by aligning authority with accountability, developing leaders’ decision-making capability, and creating systems that support performance and growth. - Emotional Intelligence - Foster trust and psychological safety, navigating complex interpersonal dynamics with compassion and accountability, and adapting leadership style to support others while maintaining composure under pressure. Factors for Success: - OD, PhD, PharmD, MD, or other advanced degree in a relevant scientific discipline with experience in Eyecare. - Minimum of 10 years of experience in Medical Affairs or related scientific roles, with at least 5 years of leadership experience in managing a team of MSLs. - In-depth knowledge of Eye Care/Ophthalmology/Optometry (preferred). - Previous experience leading a Field Medical Team within a biopharmaceutical company (preferred). - Proven track record of successful relationship-building with KOLs, ECPs, and key stakeholders within the medical community. - Experience working in cross-functional teams, with a demonstrated ability to collaborate effectively with commercial, clinical, regulatory, and other business functions. - Strong leadership skills, ability to inspire and motivate others, and collaborate cross-functionally. A Few Other Details Worth Mentioning: - This position is primarily remote with required travel at approximately (50-75% for KOL engagement, field rides, scientific meetings, and team management activities. - We are passionate about our culture! Our Tarsans live our values of commitment to patients, empowerment to champion innovation, and teamwork to amplify impact! - This position reports directly to our Vice President, Medical Affairs Operations. At Tarsus, we understand the importance of attracting and retaining top talent. The expected base pay range for this position is $203,200 - $284,600 plus bonus, stock equity, and comprehensive benefits. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training. Our benefits include health, dental and vision insurance benefits to ensure your well-being. We believe in work-life balance and offer generous paid time off, including vacation, holidays, and personal days. For more details regarding Tarsus benefits, please visit: https://eb.alliant.com/26tarsusbenefitssnapshot. #LI-Remote Tarsus Pharmaceuticals, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.

Would you like to join a global organization working to advance sustainable land management and responsible supply chains? Do you want to lead the development of a strategic, data-driven platform that supports sustainability decision-making and drives impact across global supply chains? If so, the Sourcing Hub Director role could be the ideal opportunity for you. What you can expect: As a Sourcing Hub Director, you will lead the development and delivery of Preferred by Nature’s Sourcing Hub—a strategic initiative that brings together risk assessments, benchmarking, and digital tools to support advisory, certification, and project work. You will work across divisions and with external stakeholders to ensure the Sourcing Hub delivers high-quality, practical, and scalable solutions that support responsible sourcing and sustainability commitments. Working with us is never routine so in the first year, you can expect the following areas to be central to your work. - Leading the strategic direction, governance, and development roadmap of the Sourcing Hub - Coordinating the development of risk assessments and benchmarking frameworks to support sustainability services - Driving the development and continuous improvement of the Sourcing Hub platform in collaboration with Data & Technology teams - Ensuring strong cross-divisional collaboration and alignment across Advisory, Certification, and Projects - Supporting fundraising efforts and contributing to external positioning and partnerships - Managing and supporting a small team, ensuring high-quality delivery and effective coordination Your first year with us: Within three months, you will: - Build a strong understanding of Preferred by Nature’s mission, structure, services, and key stakeholders across Advisory, Certification, Projects, and Data & Technology. - Establish governance and ways of working, including setting up a Sourcing Hub reference group and clarifying roles, decision-making, and coordination mechanisms - Review existing risk assessments, benchmarks, and platform status to identify gaps and define a prioritized 6–12 month roadmap with clear ownership Within six months, you will: - Deliver priority risk assessments and benchmarking outputs, ensuring quality, consistency, and usability across organizational services - Implement standardized methodologies and quality assurance processes for risk assessment and benchmarking - Drive platform improvements (usability, structure, integration) and strengthen cross-division collaboration and engagement Within one year, you will: - Expand Sourcing Hub coverage (countries, commodities, benchmarks) aligned with organizational priorities and stakeholder needs - Embed the Sourcing Hub into Advisory, Certification, and Project workflows to ensure consistent use and value creation - Support fundraising and external positioning, contributing to partnerships and recognition of the Hub as a credible sustainability platform Important that you: - Have relevant higher education in sustainability, environmental governance, international development, economics, law, data analysis, or a related field - Bring experience in sustainability-related areas such as risk assessment, benchmarking, certification systems, or regulatory analysis - Have strong experience managing complex, cross-functional initiatives and coordinating multiple stakeholders - Demonstrate strategic thinking combined with a hands-on and pragmatic approach to implementation - Have experience working with digital platforms, data-driven tools, or product development processes - Possess strong communication skills and the ability to engage both internal and external stakeholders - Are comfortable working independently while collaborating across global teams Would also be great, but not necessary, if you: - Experience with AI-supported tools or data visualization platforms - Experience in fundraising, proposal development, or donor engagement - Experience working in an international or NGO environment If this sounds like you, we would love to hear from you! What Sets Us Apart: - Global work culture - High degree of flexibility - remote work, work from home. - An in-depth onboarding and professional training that prepares you with the right skills and knowledge to thrive in this role. - Excellent opportunities for growth and professional development - A friendly, international team of colleagues, with a pleasant work environment - Annual vacation leave in accordance with country-specific legislation How to apply: If you feel you meet the requirements of the role, please submit your CV and cover letter (in English), including salary expectations by 17th April 2026 via the application form below. Application pre-screening will be conducted during the application period. Preferred by Nature wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

• Develop & Lead Global Strategy: Drive the creation, refinement and execution of a comprehensive global health and safety strategy. • Advise senior leadership on critical health and safety trends, emerging risks, and evolving regulations, ensuring alignment with company objectives. • Ensure global consistency while tailoring programs to local requirements across regions. • Create & Implement Safety Programs: Design and roll out global safety initiatives, ensuring adherence to federal (OSHA, EPA, NEPA), state, local, and country-specific health and safety regulations. • Lead comprehensive risk assessments and develop mitigation strategies across all locations. • Oversee the procurement and maintenance of safety and personal protective equipment as needed across all regions. • Compliance & Auditing: Own the auditing and monitoring of global health and safety standards. • Prepare forecasting and budget tracking for health and safety. • Risk Management & Liability Prevention: Take the lead in identifying potential health and safety risks and securing quality, cost-effective solutions. • Coordinate with human resources to investigate accidents and incidents. • Train & Empower: Build and coordinate the delivery of training programs that equip employees, contractors, and leadership to maintain a safe work environment. • Engage Globally: Partner with regional leadership to ensure alignment and address region-specific trends and concerns.