Role Description The Clinical Trial Manager (CTM) is accountable for coordinating and driving a broad set of operational activities for one or more clinical studies or defined workstreams, under the leadership of the designated Study Lead. This individual contributor role may serve as the primary point of contact for assigned studies and provide coordination across internal cross-functional teams and external vendors to ensure studies are delivered on time, within budget, and in compliance with regulatory requirements and company policies. The CTM will support the clinical development of BBP-418 for LGMD2I/R9 Muscular Dystrophy and potentially additional indications. The ideal candidate thrives in a dynamic biotech environment, demonstrates strong problem-solving skills, anticipates risks, and maintains a high standard of quality and inspection readiness. The CTM must conduct all work activities in compliance with applicable laws, regulations, ICH-GCP guidelines, and company policies and procedures. Responsibilities may include but are not limited to what is indicated below. Responsibilities - Coordinate and drive operational activities across assigned study workstreams (e.g., start-up, enrollment, monitoring, database lock, close-out), working under the Study Lead. - Maintain and update study trackers, timelines, and deliverable logs; proactively escalate timeline risks and propose mitigation plans. - Manage CROs and external vendors across all phases of study start-up, conduct, and close-out, ensuring deliverables are on time, within budget, and fully compliant with GCP, SOPs, and regulatory requirements. - Provide oversight of clinical monitoring activities, including review of monitoring visit reports and conduct monitoring oversight visits to confirm adherence to study protocols and quality standards. - Participate in cross-functional and vendor operational meetings as required; document decisions and action items. - Oversee site-level operational activities such as specimen management, subject visit tracking, and timely data review to identify trends, discrepancies, and potential risks. - Contribute to site feasibility, selection, and initiation activities while supporting the development and approval of essential study documents, including monitoring plans, ICFs, CRFs, pharmacy, and laboratory manuals. - Oversee study supply management, review site and study budgets, and evaluate CRO/vendor invoices to ensure financial accountability and transparency. - Ensure the Trial Master File is current, accurate, and inspection-ready. - Participate in Investigator Meetings. - Support protocol and study report development. Qualifications - BA/BS in life sciences, nursing, or related field (or equivalent work experience). - At least 5 years of progressive experience in clinical operations, clinical research, or a CRO/pharma environment. - Direct experience with site management, monitoring, or clinical operations duties (site visit experience required). - Hands-on experience with eTMF systems and clinical data systems (EDC), and competency in common study tracking tools (Excel, Smartsheet, etc.). - Working knowledge of ICH-GCP and applicable regulatory requirements (FDA/EMA). - Strong organizational skills, attention to detail, and the ability to manage competing priorities. - Excellent interpersonal and written/verbal communication skills; comfortable coordinating across functional teams. Benefits - Market-leading compensation. - 401(k) with employer match. - Employee Stock Purchase Program (ESPP). - Pre-tax commuter benefits (transit and parking). - Referral bonus for hired candidates. - Subsidized lunch and parking on in-office days. - 100% employer-paid medical, dental, and vision premiums for you and your dependents. - Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA). - Fertility & family-forming benefits. - Expanded mental health support (therapy and coaching resources). - Hybrid work model with flexibility. - Flexible, “take-what-you-need” paid time off and company-paid holidays. - Comprehensive paid medical and parental leave to care for yourself and your family. - Career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching. - Celebration of strong performance with financial rewards, peer-to-peer recognition, and growth opportunities.

• Support 4-6 large, global customers post-implementation with Veeva Clinical Operations applications (e.g. eTMF, CTMS, Study Startup, etc.) • Act as a trusted advisor and own the relationship with your customers’ application owners to understand their objectives and challenges • Liaise with Veeva strategy, sales, product and/or services’ stakeholders to address customer needs • Lead meetings with customers to demonstrate success and identify additional opportunities to add value • Provide strategic guidance to optimize use of Veeva applications and help create a customer roadmap based on their business goals and needs • Facilitate customer to customer or customer to Veeva connections for collaboration opportunities and industry learning

• Support 4-6 large, global customers post-implementation with Veeva Clinical Operations applications (e.g. eTMF, CTMS, Study Startup, etc.) • Act as a trusted advisor and own the relationship with your customers’ application owners to understand their objectives and challenges • Liaise with Veeva strategy, sales, product and/or services’ stakeholders to address customer needs • Lead meetings with customers to demonstrate success and identify additional opportunities to add value • Provide strategic guidance to optimize use of Veeva applications and help create a customer roadmap based on their business goals and needs • Facilitate customer to customer or customer to Veeva connections for collaboration opportunities and industry learning

The Telephonic Critical Support Nurse supports a busy 24/7 clinical call center, responding to a wide variety of incoming calls from patients, clinicians, referral sources, and hospitals. The team provides support for chronic therapies, including Home Infusion Therapy, and handles after-hour calls for all divisions of Accredo Health Group Specialty Pharmacies. Key Responsibilities: - Triage incoming calls from patients, clinicians, hospitals, and other sources. Intervene to address life-threatening medication interruptions. - Guide patients, caregivers, and clinicians through assessment of potential disruptions in medication administration, including pump malfunction, central line problems, and patient error. - Troubleshoot issues with infusion devices, answer infusion access questions, and provide therapy support. - Coordinate communication between patients, caregivers, pharmacists, nurses, hospital staff, and physicians. - Ensure timely provision of products and supplies. - Contact appropriate personnel as needed and document transactions in patients’ electronic charts. - Maintain up-to-date knowledge of all services, products, and resources provided by Accredo, incorporating new product and service information. - Identify trends and needs within the scope of customer/client contact. Qualifications: - Registered Nurse (RN) with multistate license in good standing, with ability to obtain licensure in all 50 states. - Valid RN license in state of primary residence. Compact license required. - Bachelor of Nursing degree (BSN) preferred. - Minimum of 5 years of relevant RN experience in critical care or home infusion. - Ability to work the shifts listed above. - Proficiency with Microsoft Office software (Outlook, Word, Excel, PowerPoint, OneNote). - Understanding of legal and regulatory issues. - Ability to compile data and statistics. - Strong customer service focus and ability to counsel patients. - Ability to develop and maintain a cross-section of networks. - Strong oral and written communication and organizational skills. Schedule Information: - Shift will be four 10 hour days. Schedule will vary. - Days off will vary week-to-week - Must be flexible to work adjusted hours for team PTO coverage - Evening, overnight, and weekend shifts include a shift differential - All shifts include every third weekend and some holidays About Accredo: Accredo, Evernorth Health Services' specialty pharmacy, serves patients with complex and chronic health conditions, including PAH, Immune Deficiencies, Hereditary Angioedema, Lysosomal Storage Disorders, Blood Disorders, Parkinson's, and many others. If you will be working at home occasionally or permanently, the internet connection must be obtained through a cable broadband or fiber optic internet service provider with speeds of at least 10Mbps download/5Mbps upload. For this position, we anticipate offering an hourly rate of 33 - 56 USD / hourly, depending on relevant factors, including experience and geographic location. This role is also anticipated to be eligible to participate in an annual bonus plan. At The Cigna Group, you’ll enjoy a comprehensive range of benefits, with a focus on supporting your whole health. Starting on day one of your employment, you’ll be offered several health-related benefits including medical, vision, dental, and well-being and behavioral health programs. We also offer 401(k), company paid life insurance, tuition reimbursement, a minimum of 18 days of paid time off per year and paid holidays. For more details on our employee benefits programs, click here. About Evernorth Health Services Evernorth Health Services, a division of The Cigna Group, creates pharmacy, care and benefit solutions to improve health and increase vitality. We relentlessly innovate to make the prediction, prevention and treatment of illness and disease more accessible to millions of people. Join us in driving growth and improving lives. Qualified applicants will be considered without regard to race, color, age, disability, sex, childbirth (including pregnancy) or related medical conditions including but not limited to lactation, sexual orientation, gender identity or expression, veteran or military status, religion, national origin, ancestry, marital or familial status, genetic information, status with regard to public assistance, citizenship status or any other characteristic protected by applicable equal employment opportunity laws. If you need a reasonable accommodation to complete the online application process, please email seeyourself@thecignagroup.com for assistance. Please note that this email inbox is dedicated to accommodation requests only and cannot provide application updates or accept resumes. The Cigna Group has a tobacco-free policy and reserves the right not to hire tobacco/nicotine users in states where that is legally permissible. Candidates in such states who use tobacco/nicotine will not be considered for employment unless they enter a qualifying smoking cessation program prior to the start of their employment. These states include: Alabama, Alaska, Arizona, Arkansas, Delaware, Florida, Georgia, Hawaii, Idaho, Iowa, Kansas, Maryland, Massachusetts, Michigan, Nebraska, Ohio, Pennsylvania, Texas, Utah, Vermont, and Washington State. Qualified applicants with criminal histories will be considered for employment in a manner consistent with all federal, state and local ordinances.