• Provide medical monitoring for assigned projects • Function as medical representative on the project team • Provide medical consultation to clients • Review individual adverse experience reports • Provide reports to FDA or other regulatory agencies • Review data listings of safety data • Support preparation of clinical protocols

• Support development and execution of the United States Medical Affairs strategy for encaleret in ADH1 and chronic hypoparathyroidism, and support Medical Affairs launch readiness and lifecycle planning, serving as an internal medical expert with scientific rigor and patient focused decision making • Lead integrated evidence generation planning and manage execution, including real world evidence generation, Phase 4 studies, registries, investigator initiated research support, and data integration activities • Lead an omnichannel Health Care Professional engagement strategy, integrating field and digital scientific exchange to gather insights and inform internal Medical Affairs programs • Build and sustain strategic relationships with key opinion leaders, investigators, and external stakeholders across endocrinology, nephrology, and related specialties, and lead advisory board and expert panel planning and execution • Partner with Clinical Development to support ongoing and planned clinical trials and contribute to scientific data disclosure and publication strategy development in collaboration with Scientific Communications • Provide medical leadership for peer to peer scientific exchange and external education programs, including scientific presentations and representation at scientific congresses, clinical meetings, and external forums • Serve as medical reviewer and approver for medical, commercial, and patient advocacy materials, and support patient finding initiatives and Field Medical strategy and training in partnership with cross functional stakeholders, ensuring compliance with applicable regulations and internal Medical Affairs policies

• Lead the development of integrated global medical plans that drive asset strategy and scientific excellence in lupus • Provide strong medical and scientific input to shape clinical, evidence generation, and launch readiness activities • Interpret and communicate complex clinical data to both internal and external stakeholders with scientific precision and clarity • Contribute to data generation efforts, including registrational, post-approval, and investigator-initiated studies • Partner with cross-functional teams (Clinical Development, Regulatory, HEOR, Commercial, and others) to ensure alignment and scientific integrity • Build and maintain trusted relationships with key external experts, professional societies, and advocacy groups • Provide clinical leadership during congress planning, advisory boards, and educational activities • Collaborate effectively across functions and with external partners to ensure scientific consistency and alignment across medical deliverables

• Provide study, project and program-specific medical monitoring and review services • Leading of all medical aspects of contracted tasks • Supervising of safety variables • Discussing with clients, investigators and healthcare professionals of medical issues in the pre and post approval services by using accurate medical judgment, interpretation and decision • Provide medical consultation to team members and answer study related medical questions • Communicate clearly with associates and clients, maintaining an open line of communication to ensure all procedures are followed appropriately • Analysis and assessment of safety data to identify and run emerging safety signals • Medical review of individual case safety reports, serious adverse event reports and clinical outcome reports. • Assist in Business Development activities • Present PPD standard medical safety processes to clients at business development meetings and connect with various medical communities to explore and expand PPD business • Participate in training of project teams • Provide therapeutic and protocol training as needed • Write, review and approve reports, regulatory submissions and protocols, ensuring that the medical content is accurate and complete.