• Provide statistical leadership across one or more clinical programs • Lead the development and review of statistical deliverables, including protocols and regulatory submission materials • Serve as a key statistical representative in cross-functional team discussions • Ensure statistical approaches comply with regulatory standards and industry best practices • Review and interpret analysis outputs for accuracy and regulatory compliance • Collaborate with cross-functional teams • Communicate statistical concepts clearly to stakeholders

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: - Accountable for global study delivery within agreed timelines and budget with appropriate inspection readiness quality - Leads all aspects of assigned clinical study(ies) - Leads global cross-functional study team (including oversight of external partners) and acts as point of escalation for resolution of issues within assigned study(ies) - Ensures alignment of study goals with clinical operations and corporate goals and objectives Essential Functions of the job: Cross-Functional Leadership - Leads the global cross-functional study team effectively, ensures effective decision making, and acts as point of escalation for resolution of study related issues - Leads external vendors management involved in study delivery - Builds trust and relationship with regional subject matter experts and supports the delivery of their local study objectives - Collaborates with key stakeholders across the organization and provides regular updates on study progress to senior management as required - Represents the study team at internal meetings and leads the cross-functional Clinical Study Team (CST) meetings - Participates and presents at various topics of Clinical Study Management - Participates in Clinical Operations Process improvement initiative Planning and Execution - Leads planning and management of the assigned clinical study(ies) from feasibility through closeout activities - Generates, manages, maintains, and communicates high quality study timelines and tracks progress towards these - Ensures that the clinical studies are operationally feasible along with Global Clinical Program Lead, oversees trial feasibility, trial allocation and site selection process across all regions - Ensures timely availability of high-quality study documents to allow study submission to regulatory authorities and ECs/IRBs - Provides oversight to study start up and site activation plans - Ensures study plans (eg project management plan, monitoring plan, Trial Master File plan, data monitoring plan, ...) are created, updated and distributed timely and implemented appropriately - Ensures study systems and tools are set up timely, correctly and are functioning properly. Ensures study level information is updated on an ongoing basis in all systems - Implements RBQM end-to-end processes on time within the allocated study (e.g., periodic reviews, centralized monitoring analyses, action items) - Ensures relevant study specific training is developed and implemented and ensures training records are well documented and filed - Ensures Trial Master File for study is created, maintained and QC’d on a regular basis as per the study TMF QC plan - Collaborates closely with Global Clinical Supplies to forecast study drug and timely delivery of supplies to sites - Supports and as needed drives overall data cleaning timelines in close collaboration with Data Management and other stakeholders (including but not limited to regional clinical operations teams and medicator monitor) - Ensures planning and execution of the Clinical Study Report in collaboration with Medical Writing and relevant CST members Quality and Risk Management - Monitors study activities to ensure compliance with the study protocol, SOPs, all study plans, ICH/GCP and all other relevant regulations - Regularly reviews and manages quality-related GCO metrics to be within acceptable limits - Ensures inspection readiness at any point in time throughout the study life cycle - Works with cross-functional study team to identify, interpret, and evaluate issues on the study and ensures corrective and preventative actions are implemented - Ensures senior management and other key stakeholders are informed of risks and challenges and ensures risk mitigation plans are put in place and implemented - Prepares team for quality assurance audits and inspections - Collaborates with CST members and other colleagues to ensure cross-team, site learnings, and best practices are shared - Leads improvements and partners with study team members to enhance the efficiency and the quality of the work performed on assigned studies - Contributes to development, optimization and review of work instructions and SOPs as required Budget and Resources - Works with the sourcing team to select and manage study vendors, approving invoice payment throughout the study - Manages study budgets, including baseline budget evaluation, change control, study closure budget, presents study budget for senior management engagement - Adheres to clinical study budgeting processes and provides input to finance on budget accruals and forecasts - Identifies and manages study team resource needs and establishes contingency plans for key resources. - Monitors Clinical Study Team resource utilization over the study life cycle - Ensures clinical studies at a project level are executed within endorsed time, quality, and cost parameters Supervisory Responsibilities: - NA Computer Skills: - MS Office, Project Planning Applications, Clinical Trial Management Systems Other Qualifications: - Proven Project Management experience in Global Clinical Studies (Oncology experience preferred) - Advanced knowledge of clinical operations methodologies, in depth understanding of all aspects of clinical study processes - Able to independently lead global clinical studies - 6 or more years of progressive experience in clinical research within biotech, pharma or CRO industry Travel: - Travel might be required as per business need. Education: - Bachelor’s Degree in a scientific or healthcare discipline required *, Higher Degree preferred. * Exceptions might be made for candidates with relevant clinical operations experience. Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. - Fosters Teamwork - Provides and Solicits Honest and Actionable Feedback - Self-Awareness - Acts Inclusively - Demonstrates Initiative - Entrepreneurial Mindset - Continuous Learning - Embraces Change - Results-Oriented - Analytical Thinking/Data Analysis - Financial Excellence - Communicates with Clarity Salary Range: $118,600.00 - $158,600.00 annuallyBeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com.

Site: Mass General Brigham Health Plan Holding Company, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Mass General Brigham Health Plan is an exciting place to be within the healthcare industry. As a member of Mass General Brigham, we are at the forefront of transformation with one of the world’s leading integrated healthcare systems. Together, we are providing our members with innovative solutions centered on their health needs to expand access to seamless and affordable care and coverage. Our work centers on creating an exceptional member experience – a commitment that starts with our employees. Working with some of the most accomplished professionals in healthcare today, our employees have opportunities to learn and contribute expertise within a welcoming and supportive environment that embraces their unique and varied backgrounds, experiences, and skills. We are pleased to offer competitive salaries and a benefits package with flexible work options, career growth opportunities, and much more. Job Summary The Clinical Pharmacy Informatics Lead is responsible for the day-to-day management, configuration, and optimization of clinical pharmacy systems and data that support the health plan’s pharmacy benefit across all lines of business. This role operates at the intersection of Clinical Pharmacy, Pharmacy Operations, IT, Finance, Compliance, Quality, and Enterprise Analytics to ensure systems accurately translate clinical intent into operational workflows, claims adjudication, and analytics that drive business objectives. This position leads the implementation and ongoing maintenance of clinical pharmacy operations, including formulary and utilization management builds, clinical edits, benefit structures, and drug coverage logic within core platforms. The Clinical Pharmacy Informatics Lead performs oversight of vendors (via testing and ROI evaluation support, validates system performance, troubleshoots issues, and ensures alignment between benefit design, utilization management policy, and adjudication outcomes. The role is accountable for data integrity and serves as a primary resource for identifying claims, authorization, and eligibility discrepancies that may impact member experience, provider abrasion, or reporting accuracy. A core responsibility of this role is generating actionable insights for leadership. The Lead collaborates with internal partners to identify, extract, and analyze pharmacy-related data. Working closely with analytics, quality, finance, and compliance teams, the Lead defines business requirements, interprets clinical and operational needs, validates data outputs, and communicates findings. The Clinical Pharmacy Informatics Lead plays a critical role in audit readiness by ensuring system logic, configuration documentation, testing evidence, and data traceability support CMS, state, and accreditation requirements. The role partners in audit preparation, supports universes and record validation, and assists with remediation and corrective action activities. This position also supports Stars, HEDIS, and other quality initiatives by enabling accurate identification of target populations, validating measure logic, and ensuring pharmacy data feeds and reports are complete, timely, and defensible. Additionally, the lead contributes to financial and utilization trend reporting, supporting rebate operations, budget forecasting, drug spend analysis, and identification of cost-of-care opportunities. The Clinical Pharmacy Informatics Lead identifies opportunities for automation and process improvement, contributes to SOP development, and provides subject matter expertise for system enhancements, upgrades, and vendor implementations. Success in this role requires strong technical aptitude, deep understanding of the pharmacy benefit, and the ability to convert complex cross-functional requirements into practical system and data solutions. Qualifications Education - Bachelor's Degree required and Master's Degree preferred Licenses and Credentials - Active and good-standing Pharmacist license required Experience - At least 5-7 years of experience in clinical informatics required Knowledge, Skills, and Abilities - Authority-level knowledge of clinical operations and related business processes. - Excellent leadership and supervisory skills. - Excellent problem-solving and organizational skills. - Proficient with standard office technologies and software. - Strategic and able to quickly understand and discuss situations and challenges. Additional Job Details (if applicable) Working Conditions - This is a full-time remote position that can be done from most US states Remote Type Remote Work Location 399 Revolution Drive Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $117,707.20 - $171,204.80/Annual Grade 8 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: 8925 Mass General Brigham Health Plan Holding Company, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Work Schedule Standard (Mon-Fri) Environmental Conditions Office Job Description Join Us as Associate Clinical Data Team Lead – Make an Impact at the Forefront of Innovation We have successfully supported the top 50 pharmaceutical companies and more than 750 biotechs, spanning 2,700 clinical trials across 100+ countries in the last 5 years. As part of our expert team, you’ll have the opportunity to ensure operational excellence that makes a real difference in organizational performance. As a Associate Clinical Data Team Lead, you will act as the assistant lead data manager for one or more projects, supporting the lead data manager by performing assigned tasks in study setup, data cleaning, database close-out, and other associated tasks. What You’ll Do: • Applies relevant components of the project protocol to daily tasks with guidance. • Delivers study specific training to junior associates for assigned projects. • Coordinates data cleaning tasks and delegates to appropriate data management staff to ensure quality standards are maintained and project deliverable timelines are met with minimal supervision. • Assists with specified activities that contribute to the creation of database specifications, database build and user acceptance testing during database and edit check development. • Monitors for risks to deadlines and escalates appropriately. • Creates and maintains data management project documentation. • Participates in team and client meetings and supports the lead data manager with risk management on allocated projects. • Provides input into project forecasting of hours and identification of resource requirements. • Monitors study metrics and runs project-specific status reports for management. • Reviews data management deliverables for allocated projects following documented guidelines. • Produces project-specific status reports for management, PM and/or clients on a regular basis Education and Experience Requirements: • Bachelor's degree or equivalent and relevant formal academic / vocational qualification • Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 0 to 2 years). In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role. Knowledge, Skills and Abilities: • Good written/ verbal communication skills with a strong command of English language and grammar; good organizational, analytical/problem solving skills and attention to detail • Ability to apply knowledge and skills in a highly organized fashion while adhering to regulatory guidelines, SOPs and client expectations • Ability to work productively with support and minimal supervision • Ability to maintain a high degree of confidentiality with clinical data and client's proprietary data • Strong customer focus and excellent interpersonal skills • Proven flexibility and adaptability • Ability to work in a team environment and independently as needed • Ability to train and direct junior team members • Ability to set and meet timelines or be able to recognize and schedule changes in response to project demands Working Conditions and Environment: • Work is performed in an office environment with exposure to electrical office equipment. • Occasional drives to site locations • Occasional travel both domestic and international. Why Join Us? When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You’ll work in an environment where collaboration and development are part of the everyday experience—and where your contributions truly make a difference. Apply today to help us deliver tomorrow’s breakthroughs.