Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation. Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs. Description of Role The (Senior) Manager, Statistical Programming will support statistical programming activities across one or more therapeutic areas, ensuring high‑quality data analysis and compliance with regulatory standards. This role will contribute to the development, implementation, and maintenance of statistical reporting standards and efficient programming processes. The (Senior) Manager will work closely with cross‑functional teams to execute programming deliverables, support clinical development planning, and help enable timely and accurate data outputs for multiple indications at Centessa. Key Responsibilities - Support statistical programming activities within a team environment, ensuring alignment with project priorities. - Collaborate with cross‑functional teams on clinical study planning and execution to ensure accurate and reliable data reporting. - Ensure the quality and timely delivery of statistical analyses, data outputs, and regulatory submission deliverables. - Apply strong technical programming expertise and encourage best practices in programming tools, environments, and methodologies. - Coordinate day‑to‑day resource utilization and contribute to capacity planning in support of departmental objectives. - Supervise and mentor statistical programming staff, providing training, guidance, and performance support. - Ensure adherence to CDISC standards (SDTM, ADaM) and compliance with applicable regulatory requirements. - Oversee and perform the development of tables, listings, and figures (TLFs) for clinical study reports and related deliverables. Qualifications - Bachelor’s degree required; advanced degree strongly preferred. - 8+ years of experience within biotechnology, pharmaceutical, or CRO settings required. - Prior experience with both early‑phase and late‑phase clinical trials required - Prior experience working on efficiently working with Adhoc - Prior experience working efficiently on regulatory submissions, such as NDA and EMA filingsSolid understanding of statistical reporting processes, regulatory expectations, and the software development life cycle. - Proficiency in SAS programming; familiarity with R or Python is a plus. - Hands‑on experience working with CDISC standards (SDTM, ADaM) and programming from raw datasets through analysis‑ready outputs. - Strong written and verbal communication skills. - Ability to work effectively in a cross‑functional, matrixed environment and contribute proactively to team deliverables and problem‑solving. Compensation The annual base salary range for the manager level is $120,000.00 to $157,000.00. The annual base salary range for the senior manager level is $145,000.00 to $190,000.00. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, and job knowledge. In addition to base pay, this role is eligible for a discretionary annual bonus and participation in our equity program, allowing you to share in Centessa’s long-term success. Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program. Work Location The (Senior) Manager, Statistical Programming role is a remote role based in the US, with occasional travel. POSITION: Full-Time, Exempt EEOC Statement: Centessa Pharmaceuticals believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Centessa Pharmaceuticals will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more. Role Description This role offers the opportunity to lead and execute high-impact people programs across the organization. As a Program Manager, People, you will be responsible for translating strategic initiatives into actionable plans, driving adoption of key HR platforms, and ensuring seamless execution of programs that support employees and organizational growth. You will work closely with cross-functional stakeholders, including HR, Legal, Finance, and IT, to deliver M&A integrations, learning initiatives, and centralized knowledge management. The position requires strong project management, organizational skills, and the ability to operate effectively in a fast-paced, dynamic environment. This role is remote but may include occasional travel and offers the chance to shape impactful people-focused initiatives across the enterprise. - Lead the design, rollout, and continuous improvement of centralized HR knowledge repositories, ensuring adoption and sustainability. - Support M&A integration efforts by coordinating cross-functional teams, tracking milestones, and maintaining a People team integration playbook. - Translate business priorities into structured, actionable plans with defined milestones, risks, and success metrics. - Partner with communications and stakeholders to plan and execute change management for people programs. - Assist with planning and execution of performance, talent, and learning initiatives, including LMS rollout and adoption. - Provide project support for high-priority initiatives, bringing clarity and structure to ambiguous or complex programs. - Act as a trusted partner and advisor across People and cross-functional teams, ensuring alignment and accountability. Qualifications - 5–8+ years of experience in People Operations, HR Program Management, or related business operations roles. - Strong program and project management skills with proven ability to manage multiple workstreams. - Experience supporting cross-functional initiatives involving HR, Legal, Finance, and IT. - Excellent stakeholder management, communication, and organizational skills. - Ability to operate effectively in fast-paced, ambiguous environments with a high degree of autonomy. - Preferred: Experience with M&A integration, LMS implementation, HR systems, centralized knowledge repositories, and change management. Benefits - Competitive hourly rate of $60–$63/hr with potential for extension or full-time conversion. - Fully remote work with flexibility and autonomy. - Comprehensive medical, dental, and vision coverage. - 401(k) with employer match. - Unlimited PTO, paid holidays, and paid parental/adoption leave. - Additional benefits include legal insurance, home internet stipend, and pet insurance. - Opportunity to work in a dynamic, cutting-edge environment with impactful enterprise-wide initiatives.

• Define and govern project implementation methodology, quality standards, control / governance and continuous improvement for delivered projects and practices • Full ownership & accountability of projects (Day 1) • Supporting Service’s Director in developing, building and maintaining effective and highly efficient project management team and drive multi-million revenue targets • Oversee several accounts projects from managerial perspective, as well as personally manage projects as individual contributor • Closely working with sales, R&D, Project Managers and cloud teams for the delivery and successful completion of projects and activities • Responsible for customer satisfaction and transaction survey results conducted for project management community • Defining project goals and delivery plans, KPIs for project managers and objectives • Initial point of contact and escalation, directly responsible for the rollout/delivery of products, services and production • Directly responsible for improving and maintaining long-term customer satisfaction goals • Develop and maintain positive and productive long term working relationship with customer’s business and operations managers, as trusted advisor • Work jointly with sales to promote and expand sales of NiCE solutions, as well as value added services such as training and consulting • Provide guidance to other PMs while working with the assigned major account • Identify, drive / executive continuous improvement initiatives that bring us long term positive impact for Major Account Program • Serve as an escalation point for the customer

• The Physician Program Director (PPD) focuses on establishing formal Impella programs through sustainable relationships with account stakeholders and key opinion leaders (KOLs) within the field of hemodynamic support. • The PPD is responsible for developing and managing strategic relationships with key opinion leaders, thought leaders, and subject matter experts to support the organization’s scientific, medical and commercial goals. • Ensure effective engagement, collaboration, and communication between the company and its network of experts to enhance brand credibility, education, and innovation. • Represents all aspects of Abiomed and acts as a field liaison to connect hospitals to internal resources such as the medical office, research, marketing, and executive teams. • Collaborates with hospitals and hospital administrators to identify areas for program efficiencies through best practice implementation, protocol development, and workflow improvement, ensuring long-term program sustainability. • Works to identify program gaps and align internal resources as appropriate to support the hospitals' goals. • Collaborates with systems of care and Integrated Delivery Networks (IDNs) to support the implementation of best practices across the hospitals within the system. • Develops and implements a comprehensive KOL engagement strategy aligned with brand and therapeutic area objectives. • Understands hospital market dynamics, uncovers gaps in operational efficiency and patient care, and deploys appropriate tools that will ultimately allow us to reach more patients. • Advocates on behalf of heart recovery programs to health system administration & engages with hospital administrators to gain alignment on projects. • Identifies and develops new and emerging key opinion leaders through key customer visits, HQ executive programs, regional education courses and local programs. • Serves as a corporate liaison between Key Opinion Leaders, IDNs, Healthcare System leaders, and Abiomed’s Executive team, Management, Marketing, Clinical Research and Sales. • Collaborates cross functionally with internal partners to align KOL initiatives. • Executes and facilitates important and integral customer meetings at major medical tradeshows. • Communicates routinely with all members of the sales and Abiomed leadership team as outlined.