Penumbra, Inc.

• Drive the process of clinical study budget negotiations with the clinical study sites (e.g., hospitals) for multiple clinical studies. • Prepare and negotiate site clinical trial budgets and budget amendments. • Act as a key liaison between the Clinical Research and Legal Departments. Submit contract requests for clinical studies and investigator-sponsored studies and follow through with internal and external stakeholders to completion. • Provide periodic updates to management regarding site start-up progress related to their strategic impact. Communicate potential or actual delays and propose actions to ensure that project timelines are met. • Communicates regular updates to clinical project manager and other study staff. • Proactively identifies potential issues that may arise with budget and contract negotiations • Partner closely with Legal team to manage timelines and expectations for new and changing clinical studies on a regular basis. • Adhere to the Company’s Quality Management System (QMS) as well as domestic and global quality system regulations, standards, and procedures. • Understand relevant security, privacy and compliance principles and adheres to the regulations, standards, and procedures that are applicable to the Company. • Ensure other members of the department follow the QMS, regulations, standards, and procedures. • Perform other work-related duties as assigned.

• Manage a team of statistical programmers engaged in medical device clinical research activities. • Provide statistical programming support for multiple projects. • Build relationships and promote collaboration across functions. • Ensure the quality, integrity, and timely delivery of programming deliverables supporting clinical studies, publications, and regulatory submissions. • Drive programming standards, process improvements, innovations, and continuous improvement. • Select, manage, train, and develop staff. • Lead resource planning for statistical programming team. • Oversee team effort related to derive data sets and programs, and analysis data set specifications. • Ensure consistency analysis of data sets following appropriate standards for clinical studies. • Develop and oversee the development of statistical code for clinical studies. • Ensure that all quality processes are followed. • Provide input into the development of CRFs and database designs. • Participate in the review of SAP and Shells. • Creation documentation for regulatory filings. • Monitor and quantify efficiency, accuracy, and timeliness of the group. • Ensure that appropriate concepts and techniques are implemented for clinical studies. • Work collaboratively with multiple stakeholders and develop appropriate contingency plans. • Lead the development of standard code (e.g., SAS, R, Python, Git) and the development of standard operating procedures. • Manage CROs and other outside vendors for statistical programming activities when appropriate.

• Provide on-site clinical support during surgical procedures, ensuring correct product usage and resolving technical issues. • Build and maintain strong customer relationships through daily interaction and a consultative, value-driven approach. • Support case and procedure planning by assessing patient needs and recommending appropriate product and therapy solutions. • Conduct consultative selling by clearly communicating clinical benefits and therapeutic value to healthcare professionals. • Deliver product, therapy, and procedural training to physicians, nurses, and internal sales teams. • Act as a clinical expert and trusted field resource, supporting the sales team with product knowledge and insights. • Monitor case outcomes, product performance, and market developments, providing structured feedback to internal stakeholders. • Collaborate with cross-functional teams and support professional education activities, including PEER meetings, workshops, and symposia.

• Provide on-site clinical support during interventional vascular procedures to ensure optimal product usage and handle technical inquiries. • Collaborate with physicians and healthcare professionals (e.g. Interventional Radiologists, Endovascular Surgeons) to support effective therapy application. • Deliver clinical product trainings, demonstrations, and education for both healthcare professionals and internal teams. • Support case planning and recommend products based on patient-specific needs. • Build and maintain strong customer relationships, identifying cross- and upselling opportunities. • Work closely with the sales team to drive product adoption and account development. • Collect and share clinical feedback, market insights, and competitive intelligence. • Participate in product launches and stay up to date with trends in the endovascular field.

• Provide support to regional sales teams in market development, procedural coverage, troubleshooting, education, and customer service • Develop and implement regional plans to increase market share • Educate customers on the use of Company products • Serve as primary resource for clinical support and customer needs

• Collaborate regularly with the Medical Education Director, Programs Managers, and Operations Manager to ensure program execution and process implementation are aligned with overall Medical Education strategy. • Partner with product team to align education with clinical messaging and product strategy, including aligning marketing initiatives. • Lead all aspects of program planning to execution, including agenda and content creation, attendee registration, logistics coordination, and on-site clinical support for programs such as CE program, workshops, case observations, and other national/regional educational events • Collaborate with leadership to maintain standard program templates and update new templates for pilot programs. • Maintain and update agenda templates and speaker slide decks as needed to ensure consistency and quality across programs. • Develop and maintain a structure to facilitate onsite support for programs. • Ensure compliance of all programs per the FDA and company-specified guidelines. • Deliver and provide quarterly updates to the Area Directors and their respective sales team on analysis of programs and provide guidance on medical education resources. • Develop and analyze program metrics, attendee feedback, utilization trends, and educational outcomes to identify opportunities for process improvement and increased program effectiveness • Build and maintain key relationships with faculty, sales, inter-departmental teams, and third-party vendors. • Ensure HCC requests are completed in a timely manner to support each program and coordinate timely expense submissions to Operations team and compliance, abiding by the Sunshine Act, as appropriate. • Guide and mentor, in partnership with managers, both new and existing Medical Education Program Coordinators, Associates, and Specialists by sharing best practices and current protocols to support their professional development. • Achieve and maintain clinical and disease state knowledge to create effective and accurate learning solutions for Medical Education. Understand the applicability of competing products to the treatment of diseases and medical conditions. • Adhere to the Company’s Quality Management System (QMS) as well as domestic and global quality system regulations, standards, and procedures. • Understand relevant security, privacy and compliance principles and adhere to the regulations, standards, and procedures that are applicable to the Company. • Ensure other members of the department follow the QMS, regulations, standards, and procedures. • Perform other work-related duties as assigned

• Responsibility for the sustainable development and targeted expansion of the sales territory • Establish and maintain long-term partnerships with hospitals and interventional physicians in radiology, vascular surgery and cardiology • Provide technical consultation and clinical support for the use of Penumbra’s innovative products • Independently execute product launches and deliver compelling presentations to clinicians and procurement teams • Conduct strategic analysis, develop and further grow existing accounts and identify new market opportunities • Build and maintain close relationships with relevant healthcare decision-makers and key opinion leaders • Implement regional sales and marketing strategies with a high degree of autonomy • Actively support interventional procedures and provide hands-on assistance in the clinical environment • Represent Penumbra at congresses, workshops and professional events

• Planning, coordinating and delivering medical continuing education and training programs in close collaboration with Sales and Marketing (includes approx. 35% travel) • Organizing the complete event and training logistics (venues, travel, materials, demonstrations and hands-on sessions with medical products) • Operational management of budgets, compliance requirements (HCC) and reimbursements for healthcare professionals in coordination with Accounting • Primary point of contact for physicians — from registration through follow-up, including organizational and technical support • Assessing needs and further developing training formats in close alignment with cross-functional teams • Monitoring KPIs, reporting results and continuously optimizing the programs • Supporting and coaching internal teams as needed • Tracking trends in MedTech and medical education to continuously advance the programs

• Plan, develop, and execute regional sponsorships and engagement activities across third-party congresses, conferences, and events. • Partner with local and international Sales & Marketing teams to design and deliver integrated campaigns, materials, and tools that strengthen brand presence and impact. • Own the annual event and congress planning cycle in alignment with Marketing leadership, including budgeting, prioritization, and execution planning. • Manage and track event budgets throughout the year, proactively identifying risks and ensuring transparency to support timely decision-making. • Ensure full compliance for all activities involving Healthcare Organizations (HCOs) and Healthcare Professionals (HCPs), in line with internal and external regulations. • Collaborate closely with key internal stakeholders (Technical Services, Legal, Compliance, Finance, Administration) to ensure smooth planning and execution. • Lead the end-to-end execution of congresses and events, including speaker management, booth coordination, logistics, travel, accommodation, catering, and creative assets. • Provide regular updates to management on progress, outcomes, and impact of marketing activities, including insights and recommendations for continuous improvement.

• Planning, coordination and implementation of regional congress, event and sponsorship activities to strengthen brand presence and support company objectives • Development and execution of the annual events and congress plan, including budget responsibility, prioritization and performance tracking in coordination with the Head of Marketing • Design and implementation of target-group-specific marketing campaigns and development of materials and tools in collaboration with local and international sales and marketing teams • Independent organization and execution of congresses and professional events (including logistics, speaker management, exhibition appearances, and travel and hotel coordination) • Management and monitoring of event budgets and early identification and communication of risks • Close collaboration with internal stakeholders (Sales, Technical Services, Legal, Compliance, Finance and Administration) to ensure successful delivery of marketing activities • Ensuring compliance requirements when interacting with Healthcare Professionals (HCPs) and Healthcare Organizations (HCOs) • Analysis and reporting of event and marketing activities and derivation of optimization measures to increase effectiveness