NewAmsterdam Pharma Corporation

• Drive commercial supply chain readiness for the company’s first US product launch, including launch planning, launch cutover, operational readiness, and post-launch stabilization. • Develop and maintain an integrated commercial supply chain launch plan aligned with regulatory approval timelines, manufacturing release, quality disposition, channel readiness, and customer availability requirements. • Translate board- approved commercial plans into executable launch demand scenarios, supply volume assumptions, inventory strategies, and operational readiness actions. • Identify launch-critical risks, dependencies, decision points, and mitigation plans across supply planning, distribution, trade, quality, finance, legal, compliance, regulatory, and commercial operations. • Lead development of commercial supply planning processes for demand translation, supply allocation, inventory targets, safety stock, replenishment, expiry management, and launch demand scenarios. • Translate commercial demand plans into supply requirements, forecasts, purchase orders and inventory plans in accordance with applicable supply agreements and contractual obligations. • Develop inventory strategies that balance patient access, launch uncertainty, working capital, shelf life, and supply continuity. • Monitor performance against supply plans and implement corrective actions to address forecast changes, production constraints, distribution disruptions, or demand variability. • Partner with Market Access, Trade, Finance, Legal, Compliance, and Commercial Operations to support channel strategy, distribution model designs, order-to-cash readiness, and customer experience requirements. • Lead operational readiness and ongoing coordination for key commercial distribution processes, including order management, warehousing, returns, recalls support, temperature control, product allocation, and customer service interfaces. • Ensure distribution and logistics capabilities are scalable, compliant, and aligned with launch requirements and future portfolio needs. • Partner with Quality, Regulatory, Legal, and Compliance to ensure commercial supply chain processes comply with applicable regulations, internal policies, and product quality requirements. • Support serialization, track-and-trace, lot traceability, product security, returns verification, and applicable DSCSA-related readiness activities for US commercialization. • Define business requirements for commercial supply chain systems, master data, reporting, partner integrations. • Support creation, review, and implementation of standard operating procedures, work instructions, training materials, and controlled processes required for commercial operations. • Own day-to-day operational management and governance of key external supply chain partners, including 3PL, logistics providers, packaging or labeling partners, and other commercial operations vendors as applicable. • In consultation with the Sr. Director, develop vendor governance routines, performance metrics, business reviews, escalation pathways, and service-level expectations. • Lead issue resolution across external partners and internal stakeholders to protect patient access, supply continuity, and launch timelines. • Support contract input, budget planning, purchase order oversight, invoice review, and operational forecasting for commercial supply chain vendors. • Monitor partner performance against contractual obligations, supply agreements, service levels, forecasts, and launch readiness expectations.

• Build and execute an integrated market access strategy for pre-commercial biotech environment • Define and operationalize capabilities across pricing, contracting, trade distribution, and value communications • Lead the development of U.S. pricing strategy, scenario modeling, and lifecycle management • Design and execute payer contracting strategies across Commercial, Medicare, and Medicaid channels • Lead planning for payer contract negotiations and develop contracting frameworks • Develop pre and post deal analytics to support effective contract processes • Build foundational gross-to-net forecasting capabilities and pricing governance processes • Partner with Finance to ensure alignment with enterprise financial objectives • Lead MFN and IRA readiness planning, including scenario analysis and strategic response • Develop and manage government pricing calculations and ensure compliance • Design and establish the company’s trade and distribution model • Ensure product availability, channel efficiency, and alignment with patient access goals • Develop and lead a compelling, evidence-based value narrative to support payer access • Equip field access teams with tools and resources to communicate product value • Build and lead a high-performing team across pricing, trade, and value communications • Drive strong cross-functional collaboration across multiple departments • Monitor federal and state legislative developments related to drug pricing reform and develop mitigation strategies for access risks

Role Description We are looking for a Senior Director, Business Applications to join our IT team at NewAmsterdam Pharma. This role will manage all Finance, Legal and HR applications, working closely with the IT internal teams and Managed Service Providers. The ideal candidate must balance the role of a Business Partner for strategic support and Project Management for tactical implementations. They must also provide Production Support for refinements and retirements, ensuring seamless transitions and optimal performance of our business applications. You will drive a business-first ethos in all you do, working in partnership with various NewAmsterdam team members to achieve our goals. Key Responsibilities - Business Partnership: - Act as a strategic partner to Corporate Functions, understanding their needs and aligning IT solutions to support business objectives. - Develop and maintain strong relationships with key stakeholders to ensure alignment and support for Business initiatives. - Provide guidance and support to business units on the effective use of applications and technology. - Identify opportunities for process improvements and automation within Finance, Legal and HR applications. - Stay updated on industry trends and best practices to ensure our applications remain cutting-edge. - Project and Application Management: - Oversee the management and support of Finance, Legal and HR applications, including Concur, ADP, and Workday. - Be the IT Lead for the future ERP implementation, from selection to production and beyond. - Manage the transition from Paycom to Coupa. - Work with Finance on the support of Business Central, Paycom, and LinkSquared. - Be hands on in all applications, be the IT system owner and be comfortable going into the details on implementations, integrations and enhancements. - Address and resolve user issues, focusing on the right things at the right times for NAP. - Project Management: - Act as the project manager for all application implementations and retirements. - Develop and maintain project plans, timelines, and budgets. - Coordinate with stakeholders to ensure project goals are met on time and budget. - Vendor Management: - Manage relationships with application vendors, ensuring optimal performance and support. - Negotiate contracts and service level agreements to ensure cost-effective solutions. - Team Collaboration: - Work closely with the SVP, IT to align application strategies with company goals. - Collaborate with IT security to ensure applications meet security and compliance standards. - Coordinate with the EUS Managed Service provider for ServiceDesk, depot services, and Security Operations Center support. Qualifications - Bachelor’s degree in Information Technology, Business Administration, or a related field. - 15+ years of IT application management within Pharmaceuticals, with 5+ years focused on Finance, Legal and HR systems. - Proven experience with Workday, Concur, ADP, and Coupa. - Experience running an ERP implementation. - Strong project management skills, with a track record of successful implementations. - Excellent communication and collaboration skills. - Ability to work in a fast-paced, dynamic environment. - Experience in multiple areas of IT/Pharma and agile enough to jump in wherever needed. Benefits - Competitive base salary. - Annual bonus and long-term incentives. - Comprehensive benefits package, including health insurance, dental and vision coverage, term life and disability coverage, and retirement plans.

Role Description The Manager, Finance, is responsible for supporting the financial management of the G&A functions and providing FP&A support across CMC, R&D, and clinical trial accruals. This role will partner closely with business leaders to deliver financial insights, forecasting, reporting, and operational support to drive strategic decision-making and business performance. Location: Remote/ East coast Reports to: Sr. Director, Finance Key Responsibilities - FP&A: - Lead financial planning, analysis, forecasting, and reporting activities for G&A functions. - Support FP&A activities for CMC and R&D functions. - Manage large budgets, ensuring cost-effective operations and maximizing financial performance. - Contribute to the development of financial strategies to support clinical objectives and company growth. - Support for Business Leaders: - Partner with Business Leaders and Finance team to provide financial insights and support decision-making. - Collaborate on strategic initiatives and long-term planning for the function. - Prepare and present financial reports, forecasts, and analyses. - Accounting and Compliance: - Support Quarter Close activities for CMC and Clinical Studies accrual. - Ensure accurate and timely accounting for all transactions. - Maintain compliance with all relevant financial regulations and industry standards. - Forecasting and Budgeting: - Support the development of annual budgets, quarterly forecasts and long-term financial plans. - Monitor financial performance against budgets and forecasts, identifying variances and recommending corrective actions. - Provide financial modelling and scenario analysis to support strategic decision-making. - Systems and Technical Skills: - Utilize strong technical and analytical skills to enhance financial reporting and planning processes. - Develop and maintain complex financial models and reporting tools using Microsoft. - Prepare clear, concise, and impactful presentations in Microsoft PowerPoint for senior management and business leaders. - Experience with Adaptive Planning or similar FP&A systems is a plus. - Support continuous improvement of financial systems, reporting automation, and data integrity. - Culture: - Support a culture of continuous improvement, professional development, and collaboration. - Foster strong communication and alignment between Finance and business functions. Qualifications - Bachelor's degree in Finance, Accounting, or a related field; MBA or CPA is a plus. - Minimum of 4-6 years of finance experience, with biotechnology or pharmaceutical industry experience preferred. - Experience managing large budgets. - Advanced Microsoft Office skills, particularly Excel and PowerPoint. - Experience with Adaptive Planning or similar FP&A/planning systems is a plus. - Ability to work on a cross-functional basis to ensure achievement of functional goals and alignment with corporate objectives. - Strong analytical, strategic thinking, and problem-solving skills. - Excellent communication and interpersonal skills, with the ability to influence and collaborate at all levels. - Proficiency in financial software and ERP systems. Benefits - Competitive base salary. - Annual bonus and long-term incentives. - Comprehensive benefits package, including health insurance, dental and vision coverage, term life and disability coverage, and retirement plans. Company Description NewAmsterdam Pharma is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information, or any other basis protected by federal, state or local law.

• Responsible for managing the Quality Control tasks and reports into the NAP Quality Team. • Review CMO QC laboratory operations, ensuring compliance with regulations such as FDA, EMA, Health Canada, and Rest of Work regulatory requirements as well as Global regulatory and ICH guidelines. • Support analytical development in a quality role; ensuring data integrity; creating, reviewing and approving technical documents (such as stability reports, method validation and method verification protocols and reports and final analytical release data). • Analyze data and metrics relate to quality control to identify trends, patterns, and areas for improvement. • Establish and maintain relationships with suppliers and vendors to ensure compliance with quality control standards. • May be a subject matter expert for regulatory submissions and inspections related to Quality Control tasks and data.

Job Description: Position Overview: The Associate Director, Financial Planning and Analysis is responsible for supporting the financial management for the Clinical Division. Reports to Sr Director, FP&A Key Responsibilities: FP&A - Oversee the financial planning, analysis, and reporting for Clinical Division. - Manage large budgets, ensuring cost-effective operations and maximizing financial performance. - Contribute to the development of financial strategies to support clinical objectives and company growth. Support to Business Leaders: - Partner with Business Leaders, and Finance team to provide financial insights and support decision-making. - Collaborate on strategic initiatives and long-term planning for the function - Prepare and present financial reports, forecasts, and analyses. Accounting and Compliance: - Manage Quarterly Close for R&D Operations including Clinical Studies - Ensure accurate and timely accounting for all transactions. - Maintain compliance with all relevant financial regulations and industry standards. Forecasting and Budgeting: - Support the development of annual budgets, quarterly forecasts, and long-term financial plans. - Monitor financial performance against budgets and forecasts, identifying variances and recommending corrective actions. - Provide financial modelling and scenario analysis to support strategic decision-making. Operational Efficiency: - Analyze business processes and workflows to identify opportunities for cost reduction and efficiency improvements. - Partner with leaders to implement best practices and drive operational excellence. - Monitor key performance indicators (KPIs) and metrics to assess financial and operational performance. Culture - Support a culture of continuous improvement, professional development, and collaboration. - Ensure effective communication and alignment between finance and clinical Qualifications: - Bachelor's degree in Finance, Accounting, or a related field; MBA or CPA is a plus - Minimum of 4-6 years of finance experience, with at least 2 years in a within biotechnology or pharmaceutical industry supporting clinical teams. - Experience managing large budgets and accruals. - Knowledge and understanding of the biotechnology industry, and forecasting in late-stage clinical trials. - Ability to work on cross-functional basis to ensure achievement of functional goals and alignment with corporate objectives. - Exceptional analytical, strategic thinking, and problem-solving skills. - Excellent communication and interpersonal skills, with the ability to influence and collaborate at all levels. - Proficiency in financial software and ERP systems. Salary and Benefits: We offer a competitive base salary, annual bonus, and long-term incentives. In addition, we provide a comprehensive benefits package, including health insurance, dental and vision coverage, term life and disability coverage, and retirement plans. NewAmsterdam Pharma is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information, or any other basis protected by federal, state or local law.

Job Description: NewAmsterdam is an innovative biotech company with the experience and expertise to deliver across its ambitious clinical, regulatory, and commercial goals. Our robust scientific approach focuses on advancing a new era of life-saving treatments for lipid-related diseases. Our vision is that people at risk for heart disease can take control of their health and live longer, fuller lives. Our team is led by a world-class team of industry veterans and key opinion leaders, including some of the world’s preeminent cardiometabolic experts and we foster a passionate, supportive culture that is backed by a high level of integrity and inclusivity. The Vice President, FP&A is a senior management position reporting to the Chief Financial Officer. The VP is an innovative and a strategic thinker with a proven ability to use data and financial models to drive insights, and adept at managing ambiguity and multiple priorities. This position requires a finance professional with a high level of integrity, a customer-focused approach, and the ability to build collaborative relationships to achieve the company's financial and corporate goals. Key Responsibilities: - Provide strategic financial guidance and analysis to support decision-making processes within the organization - Lead the preparation of analyses and presentations that ensure strategic messages are effectively and appropriately communicated to members of the senior leadership, board members and other stakeholders as appropriate - Partner with the senior leadership to evaluate strategic initiatives, investment opportunities, and business development activities through financial modeling and analysis - Develop processes that enhance senior leader financial stewardship that supports the company’s transition to commercialization - Collaborate with Finance colleagues ensuring alignment of timely and accurate financial statements - Design and oversee financial and operational metrics to drive decision-making across the company - Create management tools and variance analyses to provide insights into business performance - Establish and monitor key performance indicators (KPIs) to track business performance and drive operational improvements - Oversee cash flow forecasting, GTN, working capital optimization, and liquidity analysis to support the company's financial health and growth objectives Requirements: - BS/BA in Accounting, Finance, or related field; MBA strongly preferred - 15+ years of progressive finance leadership experience, with a focus on FP&A, within life sciences, pharmaceutical or biotech - Finance leadership experience at a biotech and/ or pharma who has commercialized a product is required - Proven leadership experience, including the ability to mentor and develop team members - Demonstrated success working with cross-functional partners (Commercial, CMC, Clinical, etc.) to understand the key levers and when appropriate to implement changes to positively impact the business - Strong analytical skills and proficiency in financial modeling, forecasting techniques, and variance analysis - Ability to foresee opportunities, anticipate challenges, develop financial strategy, and implement plans to evaluate and optimize business results - Excellent communication and interpersonal skills, with the ability to effectively communicate across all levels of the organization - cross-functional teams, senior leaders and board members - Strategic mindset with the ability to translate financial analysis into actionable insights and recommendations - Ability to proactively work with cross-functional leaders to build new capabilities and processes and support organizational growth and change management - High level of initiative; organized, driven and self-motivated; ability to roll up sleeves and work with team - Ability to work in a continuously changing business environment, comfortable working in ambiguity - Remote position with travel required. Travel is expected to NAP office in PA on a regular basis NewAmsterdam Pharma is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information, or any other basis protected by federal, state or local law. Salary and Benefits: We offer a competitive base salary, annual bonus, and long-term incentives. In addition, we provide a comprehensive benefits package, including health insurance, dental and vision coverage, term life and disability coverage, and retirement plans. NewAmsterdam Pharma is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information, or any other basis protected by federal, state or local law.

Job Description: NewAmsterdam is an innovative biotech company with experience and expertise to deliver across its ambitious clinical, regulatory, and commercial goals. Our robust scientific approach focuses on advancing a new era of life-saving treatments for lipid-related disorders. Over the last decade it has become apparent that one of the major risk factors for Alzheimer’s disease, Apolipoprotein E4, is closely associated with lipid dysregulation in the brain. Based on published data from a pre-specified analysis in our phase III BROADWAY trial evaluating Alzheimer’s disease biomarkers in patients with ASCVD, including patients with at lese one ApoE4 allele, we are excited to initiate a Alzheimer’s Disease clinical program. We are looking to recruit an Executive Medical Director, Alzheimer’s Disease to strengthen our team, which is led by a world-class team of industry veterans and key opinion leaders, including some of the world’s preeminent cardiometabolic experts. The Executive Medical Director, Alzheimer’s Disease will lead the design, monitoring, data analysis, and interpretation of the Company’s clinical trials in Alzheimer’s Disease. As such, the Executive Medical Director, Alzheimer’s Disease is a critically important and visible member of the clinical development team. The Executive Medical Director, Alzheimer’s Disease position is a remote position based in either the United States or the Netherlands and will report to the Chief Development Officer. Key Responsibilities - Lead the formulation and implementation of the Clinical Development Plan while taking into consideration the strategic objectives - For clinical trials: - Protocol design: lead the clinical trial design to ensure the design support the strategic objectives. - Work with CRO medical monitors and sites to review and respond to site queries related to protocols, such as eligibility criteria, adverse event questions, drug administration, etc. - Support the PV department in oversight of the medical & safety monitoring conducted by the CRO - Ensure successful completion of trial-related documents (including clinical trial protocols, investigator brochures, medical monitoring plans, site training materials, clinical study reports, health authority responses, standard operating procedures, etc.) with cross-functional team members - Support site and subject retention - Analyze, evaluate, interpret, and report clinical data - Contribute to drafting and reviewing of clinical documents, manuscripts, presentations, and regulatory submissions - Provide clinical science related leadership to study teams - Contribute to ad-board meetings, executive committee meetings - Responsible for high quality collaboration with external stakeholders, including thought leaders, clinical investigators, regulatory agencies, contract research organizations (CROs), and academic institutions, to exchange information, address study-related issues, and facilitate effective communication and collaboration throughout the clinical trial lifecycle. - Contribute to regulatory strategy and development of sections of the IB - Maintain up-to-date knowledge of relevant science, medical information, good clinical practices, and regulatory guidance - Collaborate with—and serve as a clinical research resource for—cross-functional colleagues (e.g. in clinical operations, statistics, regulatory affairs, medical affairs, health economics outcomes research, commercial, finance) to optimize product development - Contribute to (and may be asked to represent the clinical development department in) corporate strategic and organizational initiatives - Assist in portfolio management and commercial activities as needed - Adhere to rigorous ethical standards - Travel as required both domestically and internationally for scientific meetings Requirements - M.D. degree: Completion of ACGME-accredited residency and fellowship strongly preferred - Board-certified required, with specialty in Neurology - Physician licensure in at least one state strongly preferred if based in US - At least 8-10 years of industry experience (other relevant experience e.g. post-graduate experience in the clinical and/or academic realms may also be considered on a case-by-case basis, minimum of 5 years in clinical trial design and execution) - Thorough knowledge of clinical trials design, processes and GCP and ICH guidelines. - Working knowledge of US FDA and EMEA AD related regulations and guidelines. - Ability to perform literature research, analyze and author clinical trial publications Robust analytical skills to analyze and interpret clinical trial data, evaluate study outcomes, and generate scientific evidence supporting product development, regulatory submissions, and evidence-based decision-making. - Comfortable in communicating and interacting with investigators, KOLs, and advisors. - Multi-task while remaining organized and attentive to detail - High work ethic, a trustworthy and collaborative team player - Demonstrate sound judgement in terms of handling complex, confidential, and regulated information - Ability to travel approximately 20-25% Salary and Benefits: We offer a competitive base salary, annual bonus, and long-term incentives. In addition, we provide a comprehensive benefits package, including health insurance, dental and vision coverage, term life and disability coverage, and retirement plans. NewAmsterdam Pharma is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information, or any other basis protected by federal, state or local law.

Job Description: The Associate Director of Pharmacovigilance (PV) supports the daily management and execution of pharmacovigilance operations, ensuring compliance with regulatory requirements, PV agreements, and internal SOPs. This role supports medical review and review of medical coding, vendor management, SOP development, safety responsibilities for the clinical operations, document reviews etc. This role contributes to the oversight of drug safety activities, supports cross-functional safety initiatives, and helps maintain inspection readiness across the PV function This position reports to the VP of Pharmacovigilance. Key Responsibilities: Leadership and Operational Support: - Support development and execution of PV strategy, goals, and departmental objectives. - Coordinate with external vendors and partners to support PV activities and ensure adherence to management plans and contracts. - Provide guidance to PV team members, including case managers and safety scientists, helping ensure high‑quality work output. - Assist in developing, implementing, and maintaining PV processes, SOPs, and quality standards in alignment with global regulations (ICH, FDA, EMA). Safety Data Management: - Support oversight of adverse event (AE) collection, review, and reporting from clinical trials and post‑marketing surveillance. - Participate in the medical review process for ICSRs, as appropriate. - Contribute to signal detection activities and support investigations into potential safety concerns. - Coordinate cross‑functional and vendor-supported preparation of periodic safety reports (PSURs, DSURs). - Assist in analysis of safety data to support benefit‑risk assessments, signal evaluations, REMS activities, and periodic reporting. - Support identification and management of safety database vendors. Risk Management: - Assist in development and maintenance of Risk Management Plans (RMPs). - Support risk assessments and implementation of mitigation strategies. - Collaborate with clinical development, medical affairs, and regulatory teams to ensure safety considerations are incorporated into development and commercialization plans. - Support QA with medical and safety‑related assessments for product complaints. - Contribute to SOP development and updates. Regulatory Compliance: - Support PV readiness for regulatory inspections, ensuring documentation and processes are maintained. - Assist in responding to regulatory inquiries and preparing required safety documentation. - Stay informed on evolving global PV regulations and best practices. Cross‑Functional Collaboration: - Collaborate with clinical operations, medical affairs, quality assurance, and other internal stakeholders. - Represent the PV function on internal teams as needed. Required Skills and Experience: - Advanced degree in medicine, pharmacy, nursing, or related scientific field preferred. - Minimum of 6–8 years of experience in drug safety operations (case management, signal detection, risk management, regulatory reporting). - Experience working with external vendors/CROs required. - Experience in cardiovascular disease and post‑marketing PV activities preferred. - Strong communication, collaboration, and organizational skills. - Proficiency with safety database systems and PV software tools. Salary and Benefits: We offer a competitive base salary, annual bonus, and long-term incentives. In addition, we provide a comprehensive benefits package, including health insurance, dental and vision coverage, term life and disability coverage, and retirement plans. NewAmsterdam Pharma is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information, or any other basis protected by federal, state or local law.