• Define and execute the overall clinical quality strategy and direction of the organization • Lead the design and execution of all clinical training and quality oversight for data abstraction • Serve as subject matter expert for risk-adjustment and HEDIS • Responsible for training all internal staff, partners, and vendors internationally • Responsible for execution of all Joint Quality Audit processes • Collaborate with Innovation team for new market capabilities • Maintain compliance with Inovalon's policies, procedures, and mission statement

• In collaboration with the Head of Clinical Development, provide strategic and medical leadership for the bezuclastinib clinical development program in GIST • Provide clinical and medical support to life cycle management activities in GIST as needed • Collaborate with commercial and medical affairs colleagues to support launch activities for bezuclastinib in GIST • Provide primary medical monitor responsibilities, including oversight of trial subject safety and clinical data review and interpretation for the Peak clinical trial • Design, prepare and initiate study protocols and other required documentation in compliance with project plans, federal regulations, good clinical practice (GCP) and good medical practice • Work collaboratively with matrix team members in trial execution and oversight • Provide support to the clinical trial study team to manage safety, site education, protocol-related and eligibility questions • Provide medical oversight and input into clinical trial documents including but not limited to the study protocol, informed consent form (ICF), statistical analysis plan (SAP), case report form (CRF), clinical study report (CSR) • Provide medical and scientific input into other documents including but not limited to the investigators’ brochure, regulatory filings and submissions, abstracts, manuscripts and publications, clinical study reports • Collaborate with the regulatory team to develop briefing documents and other regulatory documents in support of submissions • Interact with clinical trial sites, external clinical experts, contract research organizations (CROs) and regulatory agencies • Support investigator meetings, steering committee meetings, data monitoring committee reviews as the study physician • Assist with regulatory submissions by answering protocol-related questions from regulatory authorities, ethics committees and institutional review boards (IRBs) • Develop a deep understanding of the clinical and competitive environment and work with the asset team to develop the target product profile

• Provide strategic input to guide creation of clinically relevant educational content and ensure effective use of clinical data to reach strategic brand objectives • Independent scientific content development including analysis and interpretation of clinical data across a wide range of project types • Conduct literature searches, proactively monitor competitive landscape and perform competitive analyses • Establish strong relationships with clients and proactively seek to contribute and collaborate in client meetings • Partner with internal teams to create compelling peer-to-peer educational content and engagement projects for healthcare professionals, including slide decks, KOL video, digital and print media • Establish close partnership with copy, art and digital teams to create interactive, engaging programs utilizing scientific storytelling techniques and unique data visualization • Collaborate to create and communicate Intouch’s POV and recommendations with clients • Play key role on team to educate team members on disease state, clinical trials, treatments and competition • Support submissions for client medical/regulatory approval processes and partners with all teams to incorporate client and regulatory feedback • Demonstrate a commitment to diversity, equity, and inclusion through continuous development, modeling inclusive behaviors, and proactively managing bias. • All other duties as assigned

• Provides clinical development and medical leadership/oversight of clinical programs to ensure timely delivery of clinical deliverables. • Ensures clinical programs support patient safety and provides oversight of patient safety in clinical studies. • As the primary medical expert for assigned study(ies), they are the first point of contact internally and externally for questions regarding the study (e.g. eligibility, enrollment; safety and patient management). Monitors study progress to ensure proper study conduct and adherence to the protocol, leads data review, evaluation, and analyses with support from the cross functional team. Takes a key role in the authoring of critical study documents (e.g., CSR, IB, protocol synopsis). • Contributes to the analysis and interpretation of data generated internally or externally and present study updates, interim results, and final headline data to senior management as required. • Provides medical input and contributes to the clinical development sections of regulatory documents such as IND, CIOMS, DSUR, Dossiers, and contributing to responses to regulatory agencies regarding questions about complex clinical development issues (e.g., safety or efficacy). • Contributes to the cross functional development of clinical development plans (CDPs) that integrate pre-clinical, early clinical findings and data sciences approaches - working to ensure cross-functional alignment on an ongoing basis throughout the phases of clinical development. • Collaborates with teams on the development of translational and precision phenotyping strategies and contributes to the design of scientifically rigorous clinical development studies and programs utilizing a data biopsy signature/precision phenotype approach. Ensures that teams appreciate the clinical relevance and applicability of the approaches considered. • Identifies and engages with external Key Opinion Leaders to address scientific and medical questions relevant to the program. • Helps identify global study sites and foster relationships with study investigators. • Ensures that Serious Adverse Events are properly reported. • Implements clinical R&D policies, SOPs, and related directives. • As required, supports any needed due diligence of potential in-licensing drug candidates and/or technologies and present recommendations to leadership.