Role Description Reporting to the VP, US Patient Services, the Senior Director, National Patient Field Teams Lead is a senior leader responsible for setting strategy and overseeing all patient field-facing teams within US Patient Services, including the Case Management (Alnylam Assist™) and Patient Education Liaison (PEL) organizations. This individual will lead through two Director-level direct reports — the Director, National Case Manager Lead and the Director, National PEL Lead — and will be accountable for the integrated strategy, performance, and patient/provider experience delivered by these teams across Alnylam’s portfolio (including ONPATTRO, AMVUTTRA, GIVLAARI, and OXLUMO). This leader will serve as a unifying voice for patient field operations — driving operational excellence in case management, reimbursement, and financial assistance while also setting the strategic direction for patient/caregiver education across hATTR amyloidosis, acute hepatic porphyria (AHP), and primary hyperoxaluria (PH1). The role works in close coordination with Field Sales, Field Reimbursement, Marketing, Medical Affairs, and Patient Advocacy, and others to deliver a seamless, end-to-end patient and provider experience. Responsibilities - Strategic Leadership & Vision - Define and execute the integrated strategy for all patient field-facing teams, ensuring alignment with US Patient Services priorities and broader Alnylam commercial strategy. - Serve as the single accountable leader for the end-to-end patient field experience — from education and disease awareness through reimbursement, treatment initiation, and continuity of care. - Partner with the VP, US Patient Services on long-range planning, organizational design, and resource allocation across the combined field organization. - Actively contribute to annual business/brand planning with Marketing and senior leadership. - People Leadership & Team Development - Lead, coach, and develop two Director-level direct reports; create a unified leadership cadence across Case Management and PEL teams. - Build, retain, and inspire a high-performing, diverse organization of reimbursement professionals, regional managers, and nurse educators. - Drive talent strategy, succession planning, and ongoing development across both functions. - Foster a culture of collaboration, accountability, and patient-centricity across the combined organization. - Operational Excellence (Case Management) - Provide executive oversight of day-to-day Patient Services Case Management operations, ensuring compliance with SOPs and adherence to service quality standards. - Oversee program performance metrics, KPIs, and customer satisfaction tracking; identify trends and direct corrective action. - Ensure compliant ownership of patient services collateral (program correspondence with patients and HCPs) through Legal/Regulatory review processes. - Sponsor evaluation and adoption of new technologies and process improvements that drive efficiency and improve patient/provider experience. - Oversee management of external Patient Services vendor partners. - Field Education Strategy (PEL) - Set strategy and oversee tactical planning for the PEL team in delivering disease, inheritance, diagnostic, and product education to patients, caregivers, families, and community groups. - Champion key strategic partnerships with relevant societies and conferences to support insight generation, educational outreach, and external collaboration. - Ensure regional PEL workplans align with national priorities and integrate seamlessly with Case Management activity. - Sustain disease, diagnostic, and product expertise across the team through continued education and engagement at relevant symposia. - Cross-Functional Partnership - Partner closely with Field Sales, Field Reimbursement, Patient Services Hub, Marketing, Medical Affairs, Advocacy, and Channel Operations to ensure an aligned, seamless field experience. - Represent the integrated patient field organization on enterprise cross-functional teams and at senior leadership forums. - Collaborate with Legal, Regulatory, and Compliance partners to ensure all initiatives are developed and executed compliantly. - Serve as a voice of patients and their families within Alnylam, ensuring their needs shape decision-making. - Financial & Performance Management - Own the combined budget for patient field-facing teams and participate in overall Patient Services budget management. - Develop and report on integrated KPIs and dashboards spanning case management and patient education performance. - Present program updates, insights, and recommendations to senior management with clear rationale and financial impact. Qualifications - BS/BA degree required; advanced degree (MBA, MSN, MPH, or equivalent) preferred. RN or clinical/medical background is a strong plus given oversight of nurse educator teams. - 12+ years of progressive experience in the pharmaceutical/biotech industry, including roles spanning Patient Services, Reimbursement, Field Education, Distribution, and/or Product Marketing. - 7+ years of leadership experience managing highly effective cross-functional and/or field-based teams, including experience leading other people leaders (managing managers/directors). - Demonstrated expertise across both US patient access/reimbursement operations and field-based patient education or nursing programs. - Deep knowledge of the US payer coverage and reimbursement environment, CMS policies pertaining to access services, and pharmaceutical channel dynamics. - Knowledge of HIPAA, HITECH, and other regulations governing patient information. - Experience supporting and providing education to patients and family members affected by rare genetic diseases or other chronic illnesses strongly preferred. - Proven track record of building and managing high-performing patient support and/or field teams, and working effectively with external partners and vendors. - Strategic thinker with strong executive presence and ability to influence senior leaders and cross-functional partners without authority. - Exceptional interpersonal, communication, and storytelling skills; ability to translate scientific and operational information into clear, actionable insight. - Compassionate leader with the ability to navigate difficult conversations and model patient-centric decision-making. - Quality-driven, with strong attention to detail, sense of urgency, and accountability for execution. - Skilled at leading through change, simplifying complexity, and adapting in a fast-paced, high-energy environment. - Ability to travel up to 25% as necessary to support field teams, attend conferences, and engage cross-functional partners. Benefits - Comprehensive medical, dental, and vision coverage. - Life and disability insurance. - Lifestyle reimbursement program. - Flexible spending and health savings accounts. - 401(k) with a generous company match. - Paid time off, wellness days, holidays, and two company-wide recharge breaks. - Generous family resources and leave.

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