Alnylam Pharmaceuticals

Role Description The Senior Manager, Document Management – Patient Services will be responsible for establishing, leading, and continuously improving a centralized document management function that supports all patient services operations. This role ensures that all patient services and operational documentation, including SOPs, job aids, workflows, regulatory artifacts, training materials, and vendor documentation, is accurate, compliant, standardized, and readily accessible. The role will also support alignment between controlled documentation and Patient Services training to promote consistency, readiness, and effective execution across teams. This role will play a critical part in ensuring that document management is fully integrated with the organization’s CRM platform, enabling seamless alignment between system-driven workflows and controlled documentation to support compliance, user adoption, and operational accuracy. Remote role with travel to Cambridge, MA as necessary. Responsibilities - Develop and implement an enterprise-wide document management strategy for Patient Services. - Oversee end-to-end document processes including: - Creation and review workflows and job-aids, alongside training. - Version control and change management. - Annual or periodic review cycles. - Implement standardized naming conventions, metadata tagging, document linkages, and structured repositories. - Evaluate and manage document management systems (e.g., Veeva, SharePoint). - Partner with CRM system owners to integrate document management practices into CRM workflows and repositories. - Drive adoption of standardized documentation management practices across teams. - Advisor on documentation initiatives and serves as the Business Process Owner for Document Management. - Identify and implement process improvements related to document management and training. - Design scalable training materials, including Standard Operating Procedures (SOPs), call guides, CRM guides to support tactical implementation and updates. - Assist in the development, maintenance, and deployment of Patient Services training content to ensure materials align with controlled documents, operational workflows, and compliance requirements. - Partner with IT and CRM product teams to embed document controls and references within the CRM workflows. - Work cross-functionally with commercial training operations, compliance, IT, and HUB teams to ensure consistent process execution across multiple therapeutic areas. - Maintain synchronization between document updates and CRM process changes to ensure consistency and compliance. Qualifications - 6-8+ years of experience in pharmaceutical, biotech, or healthcare environments. - Bachelor’s degree from an accredited university. - Experience in Patient Services, Operations, Training, and Quality/Compliance. - Experience with regulated document systems (e.g., Veeva Vault, Track Wise, SharePoint governance). - Proficiency in Microsoft Office Suite, including advanced PowerPoint skills, Word, and Excel. - Strong knowledge of documentation standards and regulations related to documentation. - Proven experience building or managing document management systems/processes. - Demonstrated experience integrating CRM systems with SharePoint to enable document sharing and workflow alignment. - Proven ability to train and support patient services team members across multiple functions. Requirements - U.S. Pay Range: $131,800.00 - $178,300.00. - This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Benefits - Comprehensive benefits including medical, dental, and vision coverage. - Life and disability insurance. - Lifestyle reimbursement program. - Flexible spending and health savings accounts. - 401(k) with a generous company match. - Paid time off, wellness days, holidays, and two company-wide recharge breaks. - Generous family resources and leave.

Role Description The Manager, US Meetings Management plays a key role in the planning, execution, and continuous improvement of meetings and events in support of business and brand objectives. This role partners closely with cross-functional stakeholders to deliver high-quality, compliant programs while driving operational consistency and efficiency across the meetings management function. The Manager is responsible for end-to-end program execution, budget management, and vendor coordination, ensuring seamless delivery and a strong stakeholder experience. This individual contributes to process improvements, supports best practice implementation, and helps drive alignment across teams. Key Responsibilities - Partner with Stakeholders and Program Leads to define meeting and event objectives, ensuring alignment on goals, expectations, and deliverables. - Lead end-to-end planning and execution of meetings, events, and congresses, ensuring high-quality delivery and a seamless attendee experience. - Develop and manage program budgets, including tracking, forecasting, and reconciliation, ensuring adherence to financial guidelines. - Support hotel and venue sourcing, contract review, and negotiations to ensure alignment with program objectives and budget. - Oversee all logistical components of program delivery, including vendor management, speaker coordination, audio-visual production, technology tools (e.g., Cvent), and onsite execution. - Ensure compliance with all legal, regulatory, and corporate requirements, including Sunshine Act reporting and HCP engagement guidelines. - Drive cross-functional collaboration (e.g., Marketing, Medical, Legal, Compliance, Finance, Travel, and Communications) to ensure seamless execution and alignment throughout the program lifecycle. - Lead planning meetings, manage timelines, and hold stakeholders accountable to key milestones and deliverables. - Manage meeting documentation and approval processes, ensuring all required materials and agreements are completed accurately and on time. - Build and maintain strong stakeholder and vendor relationships to support program success. - Identify and support process improvement initiatives, contributing to the development and enhancement of SOPs and best practices. - Support administrative and operational tasks, including purchase requisitions, change orders, and sponsorship coordination. - Perform additional responsibilities as needed, contributing to team priorities and overall program success. Qualifications - Bachelor’s degree required. - 5+ years of experience in meetings and events management, with biotech/pharmaceutical industry experience preferred. - Hands-on experience with meetings management tools and technology (e.g., Cvent required). - Strong financial acumen with experience managing program budgets. - Excellent organizational and project management skills, with the ability to manage multiple priorities effectively. - Strong verbal and written communication skills, with the ability to collaborate across cross-functional teams and engage with stakeholders. - Proven ability to work in a fast-paced environment and deliver high-quality results under tight timelines. - High level of professionalism and commitment to delivering exceptional service. - Knowledge of Sunshine Act reporting requirements and pharmaceutical industry guidelines related to HCP engagement and hospitality compliance. - Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint). - Ability to travel and provide onsite support for meetings and events as needed. Requirements - U.S. Pay Range: $113,900.00 - $154,100.00 - This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Benefits - Comprehensive benefits including medical, dental, and vision coverage. - Life and disability insurance. - Lifestyle reimbursement program. - Flexible spending and health savings accounts. - 401(k) with a generous company match. - Paid time off, wellness days, holidays, and two company-wide recharge breaks. - Generous family resources and leave.

Role Description Reporting to the Field Reimbursement Director, Lead, the Field Reimbursement Director will optimize access to Alnylam products in his/her region by understanding and addressing reimbursement and patient access challenges. This position requires a professional who can leverage his/her technical expertise and experience to deliver educational, reimbursement in-service programs to all sites of care (Medical Doctors Office, Alternative Infusion Centers, Hospital Outpatient Department, etc.) and manage access and reimbursement issues by initiating as well as leading action plans to resolve these issues. A key component of this role is the ability to establish and deepen customer relationships through quality interactions with access and reimbursement focused external stakeholders at targeted strategic accounts. As such, extensive knowledge of ‘buy and bill’ products and prior experience with high-touch, specialty products is essential. The Field Reimbursement Team will be a critical component of the commercial strategy and work in close coordination with: - National Account Leads (NALs) - Health Systems Directors (HSDs) - Regional Account Leads (RALs) - Site of Care Directors - Patient Services - Broader Reimbursement team - Sales The successful candidate must be passionate about science and deeply motivated by the quest of delivering value to patients with the long-term success of the company in mind. He/she will work collaboratively with both internal and external stakeholders to build tactical plans to execute strategic imperatives. Qualifications - Bachelor’s degree required - 10+ years prior pharma/biotech experience - 5+ years of field reimbursement experience in “buy and bill” preferably in rare disease, oncology, specialty products and/or infusions/injectables - Established relationships with Medicare Administrative Contractors (MACs) highly preferred - Strong knowledge of the US payer landscape - Deep understanding of both medical benefit and pharmacy benefit across payer types (Medicare, Medicaid, commercial, VA/DoD, etc.) and sites of care (Hospital Outpatient Department, free standing centers and home infusion) - Proven ability to identify key access and reimbursement barriers to treatment and design effective resolution plans - Exceptional professional communication, interpersonal and problem-solving skills necessary to interact with decision makers (CFO and other C-suite level stakeholders) - Demonstrated ability to lead without authority in a highly collaborative matrix and fast-paced environment - Self-starter who is enthusiastic about rare disease and Alnylam’s core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people - Ability to travel up to 50% - Must reside in geography with reasonable proximity to a mid-size or larger airport Requirements - Optimizes access to the full Alnylam portfolio of products by ensuring that provider accounts understand access and reimbursement dynamics - Proactively identifies trends impacting barriers to access or reimbursement and creates solutions - Works with internal stakeholders and providers to support treatment pathways for patients - Proactively engages with key stakeholders in accounts, including Intake/Authorization teams, billing compliance, Finance executives (Revenue Cycle, Revenue Integrity), Infusion Center management and decision-makers and key Pharmacy Stakeholders - Responsible for identifying, addressing and resolving outstanding claim payment issues - Provides guidance to case managers on case-specific complex PA/Appeal issues - Collaborates with case managers on treatment site finding for the specialty business when there are no site of care options available in the treatment directory - Provides case-specific PA/Appeal support and site of care options for the rare business - Maintains relationships with Medicare Administrative Contractors (MACs) to optimize coverage for Alnylam therapies and monitors Local Coverage Determinations (LCDs) and National Coverage Determinations (NCDs) - Works with Public Policy & Government Relations team on engagement strategies and tactics regarding MACs or local policy changes as well as state-level public policy initiatives - Utilizes reporting dashboards to track critical metrics and key performance indicators (KPIs) - Ensures compliance with all corporate and industry policies in collaboration with Alnylam Legal, Regulatory and Compliance Benefits - Comprehensive benefits including medical, dental, and vision coverage - Life and disability insurance - Lifestyle reimbursement program - Flexible spending and health savings accounts - 401(k) with a generous company match - Paid time off, wellness days, holidays, and two company-wide recharge breaks - Generous family resources and leave

Role Description The Senior Director, Cardiology serves as the U.S. medical and scientific subject matter expert (SME) for ATTR amyloidosis and related cardiology disease states. This highly visible role blends scientific expertise, external leadership, and strategic influence across the cardiology landscape. - Approximately 60% of the role is externally facing, engaging Tier 1 cardiologists, centers of excellence, and key professional societies to elevate scientific exchange and partnership. - The remaining 40% focuses on internal collaboration—providing SME input into KOL strategy, evidence generation, medical education, and patient advocacy initiatives, as well as serving as a senior trainer and strategic advisor for field medical teams. Key Responsibilities - External Leadership & Scientific Engagement (≈ 60%) - Serve as the lead U.S. cardiology expert within Medical Affairs, representing Alnylam across Tier 1 KOLs, amyloidosis centers, and national cardiology societies (AHA, ACC, HFSA). - Lead executive-level scientific discussions to advance disease awareness, diagnostics, and treatment optimization. - Build and sustain deep, trust-based relationships with key external experts to inform strategy and identify collaboration opportunities. - Represent Alnylam Medical Affairs at major scientific meetings, symposia, and advisory boards. - Partner with field medical leadership to shape KOL mapping, segmentation, and engagement strategy, ensuring alignment and execution excellence. - Generate actionable scientific and clinical insights from external engagements and ensure integration into broader U.S. Medical Affairs insight and strategy processes. - Operate as a senior individual contributor, leading scientific strategy and cross-functional partnerships without formal people-management responsibilities. - Internal Strategy, Evidence & Field Enablement (≈ 40%) - Act as the cardiology SME contributing to U.S. medical strategy, evidence generation priorities, and the broader scientific platform for ATTR. - Provide SME input into cross-functional initiatives, collaborating closely with Clinical Development, HEOR, Payer Medical, and Patient Advocacy. - Support evidence generation and ISR strategies, including protocol input, data interpretation, and scientific dissemination. - Deliver advanced cardiology and amyloidosis training for field medical teams to elevate scientific capabilities and ensure consistency in engagement. - Ensure alignment of insights, field strategy, and scientific priorities across the Medical Affairs organization. - Uphold the highest standards of scientific integrity, compliance, and ethical governance across all medical activities. Key Deliverables & Success Indicators - Strong and sustained relationships with national cardiology leaders and centers of excellence. - Measurable impact on disease education, diagnostic awareness, and scientific engagement. - Integration of cardiology insights into medical strategy, evidence planning, and cross-functional initiatives. - Enhanced scientific capabilities and quality of field medical interactions. - Prominent presence and influence at key cardiology congresses and professional forums. - Full adherence to medical governance and compliance standards. Qualifications - MD or DO, Board-Certified Cardiologist required (Advanced Heart Failure or Amyloidosis specialization strongly preferred). - 8–10+ years of combined clinical and medical affairs experience, with ≥3 years in an industry medical or strategy role. - Deep understanding of the U.S. cardiology and rare disease landscape. - Demonstrated success in engaging Tier 1 KOLs and external thought leaders at the national level. - Strong cross-functional collaboration skills and ability to influence without authority. - Exceptional communication, executive presence, and data storytelling skills. - Ability to operate effectively in a fast-paced, high-accountability environment. Requirements - #LI-JB1 - #LI-Remote Benefits - Comprehensive benefits including medical, dental, and vision coverage. - Life and disability insurance. - Lifestyle reimbursement program. - Flexible spending and health savings accounts. - 401(k) with a generous company match. - Paid time off, wellness days, holidays, and two company-wide recharge breaks. - Generous family resources and leave. U.S. Pay Range $284,000.00 - $384,200.00. The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Role Description The Key Account Manager (KAM) is a field‑based commercial role responsible for strategically driving the commercial objectives of selected Alnylam products within an assigned territory in Spain. The role has a strong focus on developing and executing territory‑specific key account plans, in close cross‑functional collaboration with Medical Affairs, Marketing, Market Access, and other field‑based colleagues, to support optimized patient identification, referral, and care pathways. The KAM builds trusted partnerships with key stakeholders, ensures consistent and compliant execution of country strategy, and acts as a local ambassador for Alnylam’s RNAi platform, always operating in line with applicable legal, regulatory, and ethical standards. Qualifications - University degree in a relevant field (e.g., life sciences, health, business, or equivalent experience). - Minimum 5 years’ experience in specialty care sales and/or Key Account Management within the pharmaceutical or biotechnology industry. - Strong business acumen with the ability to think strategically and add value within complex healthcare environments. - Proven ability to build long‑term, trust‑based relationships with healthcare professionals. - Excellent communication, influencing, and stakeholder‑management skills. - Strong organizational and planning skills, with the ability to manage multiple priorities. - Willingness and ability to travel regularly within the assigned territory (including overnight travel); valid driver’s license required. - Fluency in English (written and spoken) is preferred. Requirements - Present a positive image of the company and develop awareness about RNAi platform to relevant customer groups. - Develop and execute territory‑specific strategic account plans aligned with overall product and country strategy. - Build and maintain strong, professional relationships with key healthcare stakeholders and decision‑makers. - Drive product adoption and market penetration through consistent, high‑quality engagement and communication. - Analyze territory dynamics to identify and develop relevant centers for diagnosis and treatment. - Support patient identification, diagnosis, and referral pathways through effective network management. - Collaborate closely with Medical Affairs, Marketing, Market Access, and other internal partners to ensure coordinated execution. - Organize and support local meetings, educational initiatives, and events in partnership with internal teams. - Represent Alnylam at local and national meetings, congresses, and professional events. - Ensure accurate, timely reporting and maintain high‑quality CRM data. - Conduct all activities in accordance with company policies, industry codes, and local laws and regulations. Company Description Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by “interfering” with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. Our culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people. These values influence how we work and the business decisions we make. Alnylam is extremely proud to have been recognized as one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and the UK – among others. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential.

Role Description The Associate Director, Field Systems & Technology enables field teams to effectively execute by ensuring field‑facing systems—primarily CRM and related tools—are intuitive, aligned to field workflows, and clearly understood. Reporting to the Director of Field Enablement, this role focuses on adoption, usability, and field readiness, while also serving as the enablement lead for defining business requirements and CRM enhancements. This role translates field needs into well‑defined system requirements and translates system changes back into simple, actionable guidance for field leaders and frontline teams. Key Responsibilities - Field Enablement & Adoption - Serve as the enablement owner for field-facing systems, ensuring tools support how the field works. - Enable field leaders and frontline teams to understand what systems do, how to use them, and why they matter. - Develop and deliver enablement assets (job aids, walkthroughs, FAQs, training content) tied to system usage. - Support system rollouts and updates with a strong emphasis on change management, clarity, and adoption. - Act as a trusted point of contact for field leaders on system usage, data visibility, and workflow questions. - Partner with the Training team to help accelerate the learning of field representatives to improve their business acumen and territory planning skills. - Business Requirements & CRM Enhancements - Translate field needs, execution challenges, and enablement priorities into clear business requirements. - Partner with Field leaders, Analytics, and IT to define CRM and system enhancement requirements. - Create and maintain requirement documentation (user stories, use cases, acceptance criteria) grounded in field workflows. - Participate in solution design reviews to ensure enhancements are field‑friendly and enablement‑ready. - Support UAT from a field enablement perspective, validating usability and clarity. - Lead a cross-functional team to establish governance related to Veeva Platforms including Veeva CRM. - Field Workflow & Tool Alignment - Ensure CRM and related tools align with call planning, account management, targeting, and execution workflows. - Identify friction points where systems create confusion or slow execution, and recommend improvements. - Help standardize best practices for how tools are used across the field. - Reinforce consistent usage through enablement and leadership alignment rather than enforcement. - Data Translation & Field Communication - Translate system data, logic, and outputs into plain‑language explanations for field audiences. - Help field leaders understand how data is generated, where it lives, and how to use it effectively. - Support leadership communications related to system changes and data interpretation. - Cross‑Functional Partnership - Partner closely with the Director of Field Enablement to align systems work to enablement priorities. - Collaborate with IT, field leaders, Analytics, Compliance, and vendors to deliver field‑ready solutions. - Represent the voice of the field in system planning and prioritization discussions. - Provide input into broader field enablement initiatives tied to execution effectiveness. Qualifications - 8+ years of experience in Field Enablement, Sales Operations, Commercial Operations, or Systems Enablement. - Experience defining business requirements for CRM or field tool enhancements. - Strong ability to translate between field needs, system functionality, and technical partners. - Experience supporting field leaders and frontline teams in a distributed sales organization. - Excellent communication, facilitation, and change‑management skills. Preferred Qualifications - Experience with CRM platforms (e.g., Veeva CRM or similar). - Experience in life sciences, healthcare, or complex B2B field environments. - Familiarity with call planning, targeting, or territory workflows. - Experience partnering with IT without being embedded in IT. U.S. Pay Range $174,300.00 - $235,700.00. The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Benefits - Comprehensive benefits including medical, dental, and vision coverage. - Life and disability insurance. - Lifestyle reimbursement program. - Flexible spending and health savings accounts. - 401(k) with a generous company match. - Paid time off, wellness days, holidays, and two company-wide recharge breaks. - Generous family resources and leave.

Overview The Strategic Account Lead (SAL) role leads strategic engagement and contracting with target key accounts in order to drive growth, revenue, and joint value creation for Alnylam and the customer by enabling and optimizing access to Alnylam products and driving innovation for patients and health care providers. Key Responsibilities The Strategic Account Lead (SAL) will provide innovative, influential account engagement to shape and deliver the strategy for Alnylam Strategic Accounts in order to achieve access, create value and deliver profitable growth for Alnylam. - Lead the development and execution of the comprehensive account strategy for target accounts to bring the best of Alnylam to the customer and to maximize profitability, revenue growth and market share for Alnylam - - Analyze and synthesize information from multiple sources to identify and prioritize business opportunities across the account by applying relevant frameworks and analytical methods - Work with the Alnylam Leadership Team to co-develop and agree on strategies, programs objectives and KPIs for target regional accounts aligned with organizational and brand priorities and the wider business strategy - Support the account team with the prioritization of solutions, programs and specific pull-through tactics to ensure sustainable growth and mutual value creation - Anticipate likely market and customer developments, identify third party influence factors and shape the account strategy accordingly - Partner with target healthcare systems and organized customers to foster innovation in care through the adoption of Alnylam’s products - - Engage senior level stakeholders to influence policies, decisions and perceptions to enable patients to effectively navigate the treatment journey and ensure appropriate use of Alnylam products - Facilitate the introduction of new products and indications with institutional stakeholders by ensuring adequate budget allocation at the strategic account level - Leverage a range of strategies and tactics to maximize the level and quality of access for Alnylam products - Identify programs to partner with the Organized Customer to enhance the system of care and clinical decision making - Provide insights, education and information about scientific, clinical and technological innovation - Facilitate strategic partnership with account stakeholders to create mutual value for Alnylam and customers and deliver strategic goals - - Identify and maintain strong relationships with senior business stakeholders (Chief, VP, Director) in target accounts to support access for Alnylam’s products across the company portfolio - Strengthen the perception of Alnylam as a strategic partner by sharing insights and information to support patient identification and improving the delivery of care by establishing treatment pathways and protocols - Provide clear direction to other field teams to identify and prioritize stakeholders within their target accounts - Negotiate, review and agree contracts, incorporating solutions to strengthen partnerships with strategic account stakeholders - Collaborate with other functional and business leaders to ensure adequate Voice of the Customer to inform strategic planning across all stakeholders and channels - Support the delivery of account goals for National accounts, working closely with the Strategic Accounts Team - - Support the execution and pull through of contracting and initiatives with national organized customers to ensure value maximization - Measure, report and communicate value delivered for national organized customers in order to strengthen customer partnership - Share insights gathered through customer engagement Qualifications - - Bachelor’s degree, emphasis in Accounting, Marketing, Business Administration or equivalent work experience in business management, ideally complemented by an MBA - Minimum 7 years of experience in B2B selling in a life sciences environment - Previous account management experience with health systems and/or hospitals/ IDNs - High level of confidence and capability to understand and communicate complex scientific concepts to a range of stakeholders, plus executive presence and communication skills to engage with a C-Suite audience - Expertise and understanding of dynamic market access value models such as value-based propositions and budget impact and cost effectiveness models, etc - Strong interpersonal skills including written and oral communication skills, ability to synthesize data, interpret and translate into compelling and clear commercial strategies and plans - Demonstrated ability to successfully mobilize a cross-functional team, including interpersonal skills to foster collaboration and succeed in a highly matrixed environment by leading without direct authority - Understanding of the IDN environment, including coverage and reimbursement, pricing and contracting, formulary management and health technology assessment - Strong analytical skills and ability to think critically, challenge conclusions and underlying assumptions - Ability to synthesize multi-source information (qualitative and quantitative) to develop strategic plans - Knowledge of value based healthcare and outcome based models - Executive presence and the ability to interact and negotiate with C-suite customers - Highly proficient in Microsoft; Excel, Word, and PowerPoint Additional Preferred Experience - - Master’s degree: Master of Business Administration (MBA) preferred - Active membership of relevant pharmaceutical associations would be beneficial #LI-ST1 #LI-Remote U.S. Pay Range $204,000.00 - $276,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Overview The Strategic Account Lead (SAL) role leads strategic engagement and contracting with target key accounts in order to drive growth, revenue, and joint value creation for Alnylam and the customer by enabling and optimizing access to Alnylam products and driving innovation for patients and health care providers. Key Responsibilities The Strategic Account Lead (SAL) will provide innovative, influential account engagement to shape and deliver the strategy for Alnylam Strategic Accounts in order to achieve access, create value and deliver profitable growth for Alnylam. - Lead the development and execution of the comprehensive account strategy for target accounts to bring the best of Alnylam to the customer and to maximize profitability, revenue growth and market share for Alnylam - - Analyze and synthesize information from multiple sources to identify and prioritize business opportunities across the account by applying relevant frameworks and analytical methods - Work with the Alnylam Leadership Team to co-develop and agree on strategies, programs objectives and KPIs for target regional accounts aligned with organizational and brand priorities and the wider business strategy - Support the account team with the prioritization of solutions, programs and specific pull-through tactics to ensure sustainable growth and mutual value creation - Anticipate likely market and customer developments, identify third party influence factors and shape the account strategy accordingly - Partner with target healthcare systems and organized customers to foster innovation in care through the adoption of Alnylam’s products - - Engage senior level stakeholders to influence policies, decisions and perceptions to enable patients to effectively navigate the treatment journey and ensure appropriate use of Alnylam products - Facilitate the introduction of new products and indications with institutional stakeholders by ensuring adequate budget allocation at the strategic account level - Leverage a range of strategies and tactics to maximize the level and quality of access for Alnylam products - Identify programs to partner with the Organized Customer to enhance the system of care and clinical decision making - Provide insights, education and information about scientific, clinical and technological innovation - Facilitate strategic partnership with account stakeholders to create mutual value for Alnylam and customers and deliver strategic goals - - Identify and maintain strong relationships with senior business stakeholders (Chief, VP, Director) in target accounts to support access for Alnylam’s products across the company portfolio - Strengthen the perception of Alnylam as a strategic partner by sharing insights and information to support patient identification and improving the delivery of care by establishing treatment pathways and protocols - Provide clear direction to other field teams to identify and prioritize stakeholders within their target accounts - Negotiate, review and agree contracts, incorporating solutions to strengthen partnerships with strategic account stakeholders - Collaborate with other functional and business leaders to ensure adequate Voice of the Customer to inform strategic planning across all stakeholders and channels - Support the delivery of account goals for National accounts, working closely with the Strategic Accounts Team - - Support the execution and pull through of contracting and initiatives with national organized customers to ensure value maximization - Measure, report and communicate value delivered for national organized customers in order to strengthen customer partnership - Share insights gathered through customer engagement Qualifications - - Bachelor’s degree, emphasis in Accounting, Marketing, Business Administration or equivalent work experience in business management, ideally complemented by an MBA - Minimum 7 years of experience in B2B selling in a life sciences environment - Previous account management experience with health systems and/or hospitals/ IDNs - High level of confidence and capability to understand and communicate complex scientific concepts to a range of stakeholders, plus executive presence and communication skills to engage with a C-Suite audience - Expertise and understanding of dynamic market access value models such as value-based propositions and budget impact and cost effectiveness models, etc - Strong interpersonal skills including written and oral communication skills, ability to synthesize data, interpret and translate into compelling and clear commercial strategies and plans - Demonstrated ability to successfully mobilize a cross-functional team, including interpersonal skills to foster collaboration and succeed in a highly matrixed environment by leading without direct authority - Understanding of the IDN environment, including coverage and reimbursement, pricing and contracting, formulary management and health technology assessment - Strong analytical skills and ability to think critically, challenge conclusions and underlying assumptions - Ability to synthesize multi-source information (qualitative and quantitative) to develop strategic plans - Knowledge of value based healthcare and outcome based models - Executive presence and the ability to interact and negotiate with C-suite customers - Highly proficient in Microsoft; Excel, Word, and PowerPoint Additional Preferred Experience - - Master’s degree: Master of Business Administration (MBA) preferred - Active membership of relevant pharmaceutical associations would be beneficial #LI-ST1 #LI-Remote U.S. Pay Range $204,000.00 - $276,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Overview: Reporting to the Senior Director, Access and Reimbursement, the National Director, Site of Care will optimize access to Alnylam products through the development of strategic engagement tactics and opportunities with key Alternate Site of Care accounts. This role leads a team of Strategic Account Leads who are assigned account management initiatives and strategies. This position requires a professional who can leverage their technical expertise and experience to meet Alnylam’s site of care strategy goals that builds the capacity to support patient access to our therapies and supports an enhanced experience for patients and health care providers. A key component of this role is the ability to establish the strategy, build the processes and identify opportunities that allow the site of care team to deepen customer relationships and manage the agreed upon deliverables at targeted strategic accounts. As such, extensive knowledge of ‘buy and bill’ products and prior experience with high-touch, specialty products is essential. The successful candidate must be passionate about science and deeply motivated by the quest of delivering seamless patient access to our therapies with the long-term success of the company in mind. They will work collaboratively with both internal and external stakeholders to execute strategic imperatives. Key Responsibilities: - Work with the Senior Director and Market Access Leadership to establish the comprehensive account strategy for key accounts, informed by insights from internal and external stakeholders, to bring the best of Alnylam to the customer - Strong partnership with internal legal and contracting partners to evaluate strategies and opportunities and in supporting the execution of individual agreements. - Collaborate with Commercial Leadership (Sales, Marketing, Market Access, Distribution and Operations) colleagues to ensure adequate Voice of the Customer in addition to own insights to influence strategic planning across stakeholders that encourages innovation and improves service delivery - Work with the Senior Director to identify program objectives, identify future targets and KPIs for target accounts that are aligned with organizational and customer priorities - Analyze and synthesize information from multiple sources to identify and prioritize business opportunities and potential risk across the accounts by applying relevant frameworks and analytical methods - Lead the execution of the comprehensive account strategy across the Strategic Account Lead team with Key Accounts - Works closely with internal Alnylam partners to identify enhancements for engagement with key accounts (Ways of Working) across Alnylam, key conference identification, updated language in RFPs and MSAs and resource gaps to fulfill for the team to effectively engage and execute on strategic initiatives. - Anticipate and communicate likely or transpiring market and customer developments, identify third party influence factors and shape the account engagement strategy accordingly - Coach the team in creating and fostering strong relationships and perception of Alnylam as a strategic partner with senior business stakeholders (C- and D-Suite) in target accounts, including PE-backed groups, to deliver on strategic goals for Alnylam’s products across the company portfolio - Ensure consistent, best-in-class site of care strategic account management practices across all customer engagements - Negotiate, manage and pull-through agreements that incorporate solutions to strengthen partnerships between Alnylam and strategic accounts - Manage the individual responsibility for and oversee the team’s ongoing contractual agreements and relationships with strategic accounts to strengthen partnerships and unlock new business opportunities - Lead the team in the Development, execution and oversee quarterly business reviews, strategic planning sessions, and long-term roadmap development with key accounts Qualifications: - Bachelor’s degree required, emphasis in business management; Master’s degree preferred - Minimum 10 years’ of experience in the life sciences environment - Minimum 5 years’ previous account management experience with health systems or alternate sites of care C- and D-Suite or payors - Experience leading a team of account managers - High level of confidence, exceptional written and oral communication skills and executive presence required to engage with a C-Suite audience - Strong knowledge of the US payer landscape, value-based care and outcome-based models - Demonstrated ability to successfully mobilize cross-functional partners, including interpersonal skills to foster collaboration and succeed by leading without direct authority - Deep understanding of both medical benefit and pharmacy benefit - Strong analytical skills, able to synthesize multi-source information for strategic planning and ability to think critically, challenge conclusions and underlying assumptions - Self-starter who is enthusiastic about rare disease and Alnylam’s core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people - Highly proficient in Microsoft Office Suite - Ability to travel up to 50% - Should live near a mid-sized to major airport #LI-ST1 #LI-Remote U.S. Pay Range $204,000.00 - $276,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

The Director, Health Informatics leads the strategy development and execution of health information technology (HIT) capabilities that enable Alnylam engagement with healthcare systems and providers. This role partners with U.S. health systems to help harness EHR capabilities and digital solutions to advance care delivery and improve patient outcome for rare disease patients across Alnylam’s portfolio. Key Responsibilities - Conduct workflow and technology assessments in collaboration with health systems to identify digital HIT solutions (e.g., EHR-embedded tools) to improve care pathways and outcomes across the patient journey. - Develop and lead integration of digital HIT solutions (including but not limited to diagnostic, referrals, and disease management workflow) and other educational resources to support patient identification, diagnosis and treatment workflows, and outcomes tracking within U.S. health systems. - Collaborate with Strategic Accounts, Market Access, Patient Services, Medical Affairs, and other cross-functional field teams to integrate informatics capabilities into account planning, health systems strategies, launch planning and lifecycle management. - Identify and develop strategic collaborations with HIT vendors, digital health partners, and ecosystem stakeholders where appropriate. - Support population health and data‑driven initiatives aligned to Alnylam portfolio strategy and therapeutic priorities. Qualifications - Bachelor’s degree required in life sciences, healthcare, business, health information systems or related field; Advanced degree (MBA, MPH, MS or similar) preferred - 8-10+ years of biopharma experience in health informatics; Prior experience working within health systems preferred - Deep understanding of U.S. health system environments - Strong acumen in U.S. healthcare compliance guidelines, laws, and practices - Track record of designing and implementing innovative solutions within U.S. health systems through open collaboration with cross-functional stakeholders - Flexibility to travel to Alnylam HQ and/or customers (at least 20%) Key Competencies - Strategic thinking and structured problem solving - Executive presence with strong communications and presentation skills - Cross‑functional collaboration - Comfort operating in evolving, ambiguous environments - Deep understanding of EHR platforms (Epic, Cerner, etc.) - Proficiency in Microsoft Office (Excel, Word, and PowerPoint, etc.) U.S. Pay Range $201,500.00 - $272,600.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.