• Provides scientific and technical support for health-related research, programs, and initiatives • Analyzes and interprets scientific data, supporting research and program activities • Prepares technical documentation, and collaborates with project teams and stakeholders to meet program objectives while ensuring compliance with applicable federal requirements

• Evaluates DePuy Synthes medical device products and materials for biological safety per international medical device regulations and standards, GLP (Good Laboratory Practice) guidelines and internal procedures. • Designs, initiates, coordinates, and interprets laboratory investigations for biocompatibility and toxicology studies for MD materials and products. • Applies technical expertise to solve biocompatibility problems related to the ISO 10993 standards and regulatory authority requirements for product safety. • Liaises with internal and cross-functional team members to review existing product documentation and coordinates, together with more senior staff, biocompatibility test strategies to ensure appropriate planning and execution of required testing and completion of relevant deliverables. • Reviews, interprets, and summarizes testing data and ensures appropriate documentation and coordination of central documentation procedures required for risk assessment report completion. • Interacts closely with and provides technical guidance and expertise to internal stakeholders (e.g., R&D, Clinical Affairs, Regulatory Affairs, Manufacturing, Quality Engineering, and Supplier Management). • Can support regulatory/notified body requests as part of Audits and File/Product submissions/Reviews in applicable markets. • Maintains effective communication of business-related issues or opportunities to next management level and if necessary, SMEs, via proper communication methods and/or tools. • Identifies and evaluates potential risks and drives resolution with team members, peers, PMO and management. • Participates in continuous improvement activities and actively participates in shaping processes and procedures. • Responsible for communicating business related issues or opportunities to next management level. • Responsible for following all Company guidelines related to Health, Safety and Environmental practices as applicable. • For those who supervise or manage a staff, responsible for ensuring that subordinates follow all Company guidelines related to Health, Safety and Environmental practices and that all resources needed to do so are available and in good condition, if applicable. • Responsible for ensuring personal and Company compliance with all Federal, State, local and Company regulations, policies, and procedures. • Performs other duties assigned as needed.

• RWE and Bioinformatics Analysis: Lead large-scale genomics data analysis, specifically in Chronic Kidney Disease (CKD), to extract actionable insights. • Predictive Analytics & Modeling: Develop and implement robust predictive models to forecast clinical trends and outcomes using RWE and genomics data. • Data Visualization and Communication: Create and implement innovative data visualization strategies to effectively communicate complex genomic analysis results. • Project Leadership: Own and manage genomics projects from initial concept through to final delivery, ensuring all initiatives are completed efficiently (on time and within budget). • Cross-Functional Partnership: Collaborate closely with Sales, R&D, Data Science, Business Development, Medical Affairs, and Engineering. • Data Stewardship: Facilitate the integration of genomics data with diverse data types to enrich analyses. • Reporting and Publication: Prepare detailed reports and manuscripts for publication. • Innovation and Development: Maintain current knowledge of the latest developments in genomics and bioinformatics and propose new methods for analysis.

• Senior Medical Affairs Scientists (Field) are experienced medical-scientific experts in the indication area of ATTR-CM (transthyretin amyloid cardiomyopathy) and with the drug tafamidis. • They provide external stakeholders and networks with the available medical-scientific knowledge. • Responsible for establishing and maintaining medical-scientific relationships with clinical and scientific experts in cardiology. • They also support relevant network structures and medical-scientific projects. • Senior Medical Affairs Scientists (Field) initiate and lead internal projects, contribute their medical-scientific expertise and specific experience, and support colleagues and other Medical Affairs Scientists in the ATTR-CM indication and in relation to tafamidis across functional boundaries.