Role Description The Regulatory Labeling Director will lead the strategic development of global labeling on one or more marketed products. This role will be responsible for the development and maintenance of global product labeling across a therapeutic area. This will include: - Target labeling profiles (TLP) - Company core datasheets (CCDS) - Local labeling (prescribing information, patient information) for major markets This role will be accountable for specific labeling business processes. Key Duties and Responsibilities - Ensures compliance with labeling governance requirements and associated business processes. - Leads label working groups (LWG) and represents labeling at product-specific global regulatory teams and senior labeling governance meetings: Label Review Group (LRG) and Executive Label Review Group (ELRG). - Plans and leads development and maintenance of global product labeling for one or more products, including CCDS and regional labeling (Prescribing Information [PI], Patient Information [PIL], Instructions For Use [IFU]) for select markets (e.g., US, EU, GB, CA). - Leads labeling strategy with expert ability to advise stakeholders of regulatory labeling requirements and provide oversight of health authority interactions (responses to questions, negotiations, and inspections) regarding all aspects of labeling. - Conducts research related to labeling precedent, regulations, policies, and other topics as necessary to properly advise on potential labeling impacts, strategies, or outcomes. - May lead one or more therapeutic areas and be responsible for the strategic development and lifecycle management of labeling for that/those area(s), including TLPs. Knowledge and Skills - Experience leading labeling development and regulator negotiation activities for an initial marketing application or major indication expansion. - Ability to synthesize complex concepts and actions into simple and clear messaging; communicating at all levels of the organization, from specialized experts to executive management. - Specialized depth of knowledge regarding labeling requirements globally, including development and life-cycle management of CCDS and of global regulatory authorities, including the FDA, EMA, and may include other authorities such as Health Canada, TGA. - Advanced ability to develop, use, and apply knowledge of frameworks specific to regulatory labeling, and to use this information to support regulatory responsibilities that align with business objectives. - Advanced ability to plan, prioritize, lead, and execute individual work, teamwork, and projects related to regulatory labeling in a systematic and efficient manner. - Strong attention to detail with a quality-driven mindset. - Strong understanding of the compliance and operational requirements for labeling. - Demonstrates the ability to effectively adopt and leverage emerging technologies, including structured content management for labeling, AI-driven tools, and eLabeling technologies. - Maintains a continuous learning mindset to strengthen Regulatory Labeling decision-making and operational efficiency. - Proactively remains up to date on advances in technology, AI, automation, competitive intelligence and changes in the Regulatory environment. Education and Experience - Bachelor’s degree - Typically requires 10 years of experience in regulatory affairs in the area of global labeling or related discipline, or the equivalent combination of education and experience. Pay Range $185,600 - $278,400 Disclosure Statement The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. Benefits At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations: - Medical, dental and vision benefits - Generous paid time off (including a week-long company shutdown in the Summer and the Winter) - Educational assistance programs including student loan repayment - A generous commuting subsidy - Matching charitable donations - 401(k) and so much more Flex Designation Remote-Eligible Flex Eligibility Status In this Remote-Eligible role, you can choose to be designated as: - Remote: work remotely five days per week and come into the office on occasion – you’re always welcome on-site; - Hybrid: work remotely up to two days per week; - On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

• Collaborate closely with R&D, Commercial, Access, and Corporate Communications to shape pipeline and portfolio strategies, ensuring alignment of medical plans with portfolio objectives. • Serve as the key medical representative on clinical development teams and study execution teams, providing scientific and medical expertise to support cross-functional deliverables such as early development strategy, trial designs, and recruitment. • Accountable for developing the integrated medical evidence plan for early pipeline assets- including therapeutic and diagnostic agents. • Oversee medical communication strategy and pull through in publications, congress planning, advisory boards, and KOL engagement. • Provide medical leadership across the medical matrix team, including medical positioning, field medical engagement, and external education. • Engage with key external thought leaders, medical organizations, and patient advocacy groups to inform strategy and uphold scientific credibility. • Mentor and develop medical staff within a matrixed environment. • Leverage AI to drive program, portfolio, or functional performance through prioritization and scaled adoption.

Role Description Enterprise is hiring an Assistant Director, Strategy Measurement to lead the translation of Enterprise’s strategic direction and priorities into a practical, people‑centered measurement approach. This role serves as a bridge between organizational priorities, impact measurement design, and analytics implementation, working within an established enterprise reporting and business intelligence environment alongside active governance structures and external advisory partners. The Data Analytics and Reporting (DAR) team at Enterprise helps more efficiently and effectively achieve our mission by driving the organization’s data strategy, analyzing and reporting on organizational performance, and partnering with other IT departments to strengthen our internal data systems. Responsibilities - Partner with Tech and Data leaders and internal stakeholders to define and lead implementation of Enterprise’s measurement framework, translating priorities and strategies into clear, people-centered performance measures. - Own the development and ongoing refinement of enterprise-level metrics, methodologies, and data collection standards that enable consistent tracking of progress against Enterprise priorities across divisions. - Lead prioritization and sequencing of measurement roadmap for data and analytics teams to ensure alignment with organizational goals and efficient use of resources. - Engage Enterprise leaders and drive adoption of new measurement practices and processes that align with organization-wide standards. - Partner with program, operations, and functional leaders to phase new measurement approaches and metrics into existing dashboards and reporting processes. - Partner with Data Governance leaders to define organization-wide terms and measures—clarifying purpose, ownership, and appropriate use consistent with Enterprise's data governance framework. - Lead the design and development of data visualization tools and reports that demonstrate progress on Enterprise's strategic priorities, working in partnership with the Business Intelligence team to operationalize. - Support data-related organizational change by developing adoption guides, stakeholder communications, and training materials that articulate how measurement supports Enterprise's mission, values, and long-term direction. - Lead enterprise-level analysis of performance and impact data to surface insights about what is working, identify evidence for program scaling, provide intelligence to management and executive teams, and contribute to continuous organizational learning. - Adhere to Enterprise's data privacy framework and governance standards, perform quality assurance reviews, and maintain thorough project documentation consistent with departmental and regulatory requirements. Qualifications - 7+ years of professional experience in strategy implementation, impact measurement, analytics, program management, consulting, or related fields (Master’s degree may substitute for a portion of experience). - Demonstrated experience translating organizational priorities or strategy into measurable outcomes and implementation plans. - Experience working across technical and non-technical teams, with the ability to translate leadership priorities into analytics requirements. - Strong facilitation and stakeholder engagement skills. - Excellent written and verbal communication skills for senior and executive audiences. - Strong organizational and project management skills. - Adaptable and collaborative, with experience working with diverse, multi-functional teams, virtually or in-person. - Excellent critical thinking and creative problem-solving. - Excellent organizational and time management skills; ability to work on multiple projects simultaneously. - Familiarity with issues in community development, housing policy, urban economics, demographics and/or real estate development. - Curiosity, desire for self-improvement, passion for social equity, and excitement about sharing new skills and knowledge. Requirements - Proven experience in performance reporting, strategy measurement, housing and community development. - Strong teamwork and communication skills. - Excited about learning and problem-solving. - Passion for social justice. Benefits - Comprehensive total rewards package including annual performance bonuses and generous paid leave programs. - Dental, health, and vision care plans, as well as family-building benefits such as adoption and surrogacy support. - Flexible work arrangements to promote work-life balance. - Health advocacy, Employee Assistance Program (EAP), and mental health benefits. - Financial education, wellness programs, and auto-enrollment in the company’s 401(k) plan with employer matching contributions. - Access to learning and development opportunities, including tuition reimbursement for job-related courses and certifications.

Role Description The Network Strategy Analyst will be responsible for maintaining supply chain modeling to support the growth strategy of the Ross distribution and transportation network. Develop, maintain, and progressively improve the Company’s dataset supporting supply chain activities related to: - New distribution centers - Retro-fitting and scaling existing facilities - Transportation optimizations - Other capabilities to improve the supply chain Responsible for supply chain modeling and analytics, by gathering relevant data, completing accurate, detailed analyses, and summarizing findings. Qualifications - Minimum of 2-3 years of progressive experience in supply chain consulting, distribution or transportation reporting roles or related experience - Experience with distribution center operations, network optimization, or strategic planning a plus - Requires high level of confidentiality - Must be advanced/expert with the Microsoft Office suite (Excel, Word, PowerPoint) - A detail-oriented professional, who is thorough and circumspect in planning and reporting - A keen analytical thinker, able to work through and present logistical and financial based analyses - Strong written and verbal communication skills, to present analysis and optimization results - A high energy, self-motivated individual, who can be successful in a fast-paced environment Requirements - Managing weekly/monthly reporting to monitor capacity required within the supply chain, and to identify trends impacting future capacity - Completing the analytics/modeling to support ongoing strategic planning of the processing and storage functions - Working with Transportation to provide analyses, network and route optimization, and other Transportation modeling - Manage large datasets through advanced Excel, Access, or other data analysis tool - Working with DC Engineering organization to define capacities by processing area and function - Collaboration with other functional areas including DC Finance/Supply Chain Production Planning, DC Operations, Merchandising, Planning and Allocation, Finance, and Stores Physical Requirements/ADA - No unusual physical requirements; requires no heavy lifting - Nearly all work is performed in a comfortable indoor facility - Job frequently requires sitting, handling objects with hands - Job occasionally requires standing, walking, reaching, talking, hearing, and lifting up to 10 pounds - Vision requirements: Ability to see information in print and/or electronically Supervisory Responsibilities - None Disclaimer This job description is a summary of the primary duties and responsibilities of the job and position. It is not intended to be a comprehensive or all-inclusive listing of duties and responsibilities. Contents are subject to change at management’s discretion. Ross is an equal employment opportunity employer. We consider individuals for employment or promotion according to their skills, abilities and experience. We believe that it is an essential part of the Company’s overall commitment to attract, hire and develop a strong, talented and diverse workforce. Ross is committed to complying with all applicable laws prohibiting discrimination based on race, color, religious creed, age, national origin, ancestry, physical, mental or developmental disability, sex (which includes pregnancy, childbirth, breastfeeding and medical conditions related to pregnancy, childbirth or breastfeeding), veteran status, military status, marital or registered domestic partnership status, medical condition (including cancer or genetic characteristics), genetic information, gender, gender identity, gender expression, sexual orientation, as well as any other category protected by federal, state or local laws.